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Pemanfaatan Ekstrak Kulit Buah Naga (Hylocereus polyrhizus) Sebagai Bahan Aktif Pembuatan Sabun Cair Alami Januarti, Melinda; Husni, Patihul; Christiningtyas Eryani, Mikhania
JURNAL FARMASI GALENIKA Vol 11 No 3 (2024): Jurnal Farmasi Galenika Vol 11 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v11i3.358

Abstract

Nowadays, many people are paying attention to the benefits of natural soap because it is believed to be gentler on the skin and environmentally friendly. This research aims to determine the formulation of natural liquid soap with the addition of dragon fruit peel extract that is effective and meets the requirements. The method used is an experimental method by formulating a natural liquid soap containing 0.5% dragon fruit peel extract as the active ingredient and adding cocamid-DEA as a foam stabilizer in variations of 1%, 3%, and 5%. The tests conducted include organoleptic tests, pH tests, foam height tests, viscosity tests, and skin condition tests. Research shows that the natural liquid soap produced has characteristics of a reddish-purple color, a distinctive scent, and varying consistency depending on the concentration of cocamid-DEA added, where F3 has the highest viscosity at 528.9 mPa, F2 at 525.7 mPa, and F1 at 428.9 mPa. From the pH testing results, F1 has a pH of 8, while F2 and F3 have a pH of 9. In the foam height test, all formulas met the soap foam height requirement of 1.3-22 cm. The first formulation of natural liquid soap with the addition of dragon fruit peel extract as an active ingredient, based on organoleptic tests, pH tests, viscosity, and foam height tests, produced the best results and met the requirements.
Penyuluhan Interaktif Tentang Pubertas dan Kesehatan Reproduksi Remaja bagi Siswa SMP Negeri 14 Jember Eryani, Mikhania Christiningtyas; Winarti, Lina; Wardhani, Firdha Aprilia
Jurnal Pengabdian UNDIKMA Vol. 5 No. 4 (2024): November
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v5i4.12879

Abstract

This community service activity aims to increase the knowledge of students of SMP Negeri 14 Jember regarding puberty and reproductive health in order to realize healthy adolescents for Indonesia Emas 2045. The method used in this activity is the interactive counseling method. The evaluation instrument for this community service is a questionnaire and is analyzed descriptively qualitatively and quantitatively. The results of the community service show that there is an increase in student knowledge which initially had a score of 41.4 before the counseling to 84.1 after the counseling. So that the increase in participant scores after the community service process was carried out was 42.7 or 103%. Through this community service activity, adolescents at SMP Negeri 14 Jember increased their knowledge, especially regarding puberty and reproductive health.
Formulasi Dan Evaluasi Sifat Fisik Pasta Ekstrak Binahong (Anredera cordifolia (Ten) Steenis) Dan Cangkang Telur Ayam Dengan CMC Na Sebagai Pengikat Eryani, Mikhania Christiningtyas; Aditama , Agnis Pondineka Ria
Journal of Agropharmacy Vol. 1 No. 2 (2024)
Publisher : Faculty of Pharmacy, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/joa.v1i2.1265

Abstract

Binahong (Anredera cordifolia (Ten) Steenis) is a natural ingredient that can prevent tooth decay due to plaque. The purpose of this study was to formulate and evaluate the physical properties of binahong extract paste and chicken egg shells with various concentrations of CMC Na as a binder. The paste was formulated with various concentrations of CMC Na, namely 1.5% (F1), 2% (F2) and 2.5% (F3). The physical properties of the paste studied included organoleptic, homogeneity, pH, viscosity, spreadability and foam height. The results showed that variations in the concentration of CMC Na affected the organoleptic physical properties of color, viscosity and foam height of the paste. However, variations in the concentration of CMC Na had no effect on the pH and spreadability of the paste.
Formulasi Dan Evaluasi Sifat Fisik Blush On Powder Ekstrak Buah Tomat (Solanum lycopersicum L.) Sebagai Pewarna Alami Eryani, Mikhania Christiningtyas; Syuhuriah, Ainin; Azizah, Siti Nur; Husni, Patihul
Journal of Agropharmacy Vol. 2 No. 1 (2025)
Publisher : Faculty of Pharmacy, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Blush on is a cosmetic product that is used to provide color or add aesthetics to facial makeup. Tomato fruit (Solanum lycopersicum L.) contains red carotenoid pigments which can be used as natural dyes. This research aims to formulate and evaluate the physical properties of blush on tomato fruit extract with concentrations of 3% (F1),5% (F2) and 7% (F3). The results of organoleptic research showed that F1 was light orange, F2 was bright orange and F3 was bright orange. The entire formula smells of rosae, has a smooth and homogeneous texture. The pH value of the entire formula is 6.0. Evaluation of spreadability shows that the entire formula adheres after 5 applications. The conclusion of this research is that tomato fruit extract has an effect on the physical properties of blush on powder, namely organoleptic odor and color. However, it has no effect on organoleptic texture, pH, homogeneity and spreadability
Optimasi Moringa Gum dan Hidroksi Propil Metil Selulosa dalam Sediaan Mucoadhesive Buccal Film Diltiazem Hidroklorida Sari, Lusia Oktora Ruma Kumala; Hanif, Mohammad Ainul Fakhruddin; Irawan, Eka Deddy; Winarti, Lina; Barikah, Kuni Zu’aimah; Rosyidi, Viddy Agustian; Eryani, Mikhania Christiningtyas; Febryanto, Hery Diar
Journal of Agropharmacy Vol. 2 No. 1 (2025)
Publisher : Faculty of Pharmacy, University of Jember

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Abstract

Moringa gum is a natural polymer obtained from Moringa oleifera plant and has been used as a stabilizer, binder, disintegrant, and controlled release matrix. Moringa gum has a polyuronide group, which can potentially be a mucoadhesive agent. This study used moringa gum as a mucoadhesive agent in diltiazem HCl mucoadhesive buccal film. This research aimed to determine the effect of the combination of moringa gum and HPMC on surface pH, swelling index, and in-vitro mucoadhesive residence time. Mucoadhesive buccal films were evaluated for weight and thickness uniformity, folding resistance, drug content, surface pH, swelling index, in-vitro mucoadhesive residence time, and characterization in the form of FTIR and release studies. All formulations met the tests of uniformity of weight and thickness, folding resistance, and drug content. The results showed FB as the optimum formula with a surface pH of 5.803±0.101, a swelling index of 7.031±0.134, and a residence time of 505.67±4.51 minutes. FTIR showed no interaction, and the release study showed 82.197±1.178% release at 480 minutes. In conclusion, a combination of moringa gum and HPMC mucoadhesive buccal film has been successfully prepared with moringa gum as a mucoadhesive agent that increases the residence time.
Formulasi Dan Evaluasi Fisik Lipstik Dari Ekstrak Kulit Umbi Bit (Beta vulgaris L.) Eryani, Mikhania Christiningtyas; Aditama, Agnis Pondineka Ria; Husni, Patihul; Permatasari, Lina Putri
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.417

Abstract

Lipstick is a cosmetic used to add color to the lips. Natural dyes that can be used as a lipstick component are beet (Beta vulgaris L.) skin extract. The skin of beet contains betacyanin which can give color to the lips. This study aims to determine the effect of varying concentrations of beet skin extract on the physical properties of lipstick. There are 3 lipstick formulas used with a 1% (F1), 2% (F2), and 3% (F3) concentration of beet skin extract. The research results show that F1 is pink, F2 is red, and F3 is dark red. The entire formula has even spreadability. The pH values of F1, F2, and F3 are 4.9±0.173, 5±0.3, and 5.3±0, respectively. The melting points of F1, F2, and F3 are 50.66±1.15°C, 52.66±1.15°C, and 53.66±0.58°C, respectively. The conclusion of this study is that variations in the concentration of beet extract affect the color, pH, and melting point of lipstick but do not affect the spreadability of lipstick.
Pengembangan Sediaan Losio Ekstrak Buah Naga Putih Husni, Patihul; Budianto, Muhamad Oke; Baitariza, Ardian; Eryani, Mikhania Christiningtyas; Febryanto, Hery Diar; Januarti, Melinda
JURNAL FARMASI GALENIKA Vol 12 No 3 (2025): Jurnal Farmasi Galenika Volume 12 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i3.419

Abstract

White dragon fruit (Hylocereus undatus) is a tropical fruit from a type of cactus plant that contains various powerful antioxidants. The purpose of this study was to obtain the best lotion formula containing extract of white dragon fruit based on physical evaluation. Three lotion formulas (F1, F2, F3) containing 7,5% white dragon fruit extract were prepared in this study. Physical assessment of the lotion preparation included organoleptic tests, homogeneity, pH determination, and viscosity evaluation. The results showed that the preparation was in the form of a liquid and homogeneous lotion with a white color and a rose odor. The pH of the preparation was around 5.2-6.5 with a viscosity between 1200-1800 cps. F3 is the best lotion formula based on physical evaluation during four weeks of storage with a composition of 7.5% white dragon fruit extract, 1% glycerin, 0.05% triethanolamine, 3% liquid paraffin, 0,3% methyl paraben, 2% dimethicone, 2% stearyl alcohol, 1.5% glycerol monostearate, 3% virgin coconut oil, 0.1% disodium edetate, 3% cetyl alcohol, 0.2% titanium dioxide, parfum qs, and aquadest ad 100%.
Health education method to improve anemia prevention knowledge in adolescents Adelia Firandi; Ika Norcahyanti; Mikhania Christiningtyas Eryani
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol. 10 No. 2 (2025): May 2025
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v10i2.15446

Abstract

Based on data from Riskesdas, the highest prevalence of anemia occurs in pregnant women (48.9 percent and adolescent girls aged 15-24 years (32 percent. Adolescent girls are a high-risk group for anemia due to blood loss during menstruation and the possibility of micronutrient deficiencies. Other identified causes include improper eating patterns and low adherence to consuming iron supplementation tablets (IST). To increase public knowledge about anemia, education is needed, one of which can be conducted through outreach in schools. This counseling aims to determine the students' level of understanding regarding anemia, which can subsequently enhance their knowledge and compliance with iron tablet consumption. The counseling was conducted at SMP Negeri 14 Jember on February 25, 2025, and attended by 32 student council members. The material was delivered through a PowerPoint presentation, leaflets, and games. Evaluation was conducted using a comparison of pre-test and post-test results to measure changes in students' knowledge about anemia. The results show an increase in knowledge among 71.88 percent of students, and from the statistical test results using the paired T-test, a significant result was obtained p<0.05. Based on this, educational activities aimed at preventing anemia using a counseling approach can enhance adolescents' understanding of anemia.
Optimization of Hydrolyzed Pumpkin (Cucurbita Moschata) Starch as Natural Superdisintegrant in Promethazine HCl Sublingual Tablets Winarti, Lina; Asrofi, Muhammad; Lubis, Maralodia Almira; Lestari, Tirtawati Putri; Sari, Lusia Oktora Ruma Kumala; Irawan, Eka Deddy; Febryanto, Hery Diar; Afthoni, Muhammad Hilmi; Eryani, Mikhania Christiningtyas
Science and Technology Indonesia Vol. 11 No. 2 (2026): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2026.11.2.502-514

Abstract

Acid hydrolysis of pumpkin starch is a feasible strategy for developing novel pharmaceutical excipients, particularly natural superdisintegrants for sublingual and orally disintegrating tablet formulations. Given the requirement for extremely rapid tablet disintegration in sublingual dosage forms, selecting an efficient disintegrant is a critical formulation parameter. However, native pumpkin starch exhibits limited disintegration efficiency and generally requires high concentrations, which may adversely affect tablet hardness and friability. This study aimed to optimize the acid hydrolysis process of pumpkin starch and to evaluate the performance of the optimized hydrolyzed starch as a natural superdisintegrant in Promethazine HCl sublingual tablets. A factorial design was used to examine the impact of varying hydrolysis durations (3-9 days) and hydrochloric acid concentration (5-9%) on the physicochemical characteristics of the modified starch. The optimized hydrolyzed starch demonstrated a near-neutral pH (5.17 ± 0.03), acceptable moisture content (LOD 10.20 ± 0.44%), and excellent flow properties, as indicated by a low angle of repose (23.96°) and Carr’s index (9.99%). Scanning electron microscopy revealed increased surface irregularity and porosity, while FTIR analysis indicated enhanced exposure of hydroxyl groups, consistent with partial depolymerization of the starch polymer. The amylose content increased to 35.17%, accompanied by improved water uptake and swelling capacity. The effective pore radius (25.03 ± 0.35 µm) and swelling index (70.25 ± 0.57) were markedly higher than those of native pumpkin starch (12.27 µm and 44.30 ± 0.85, respectively), although slightly lower than crospovidone (27.65 µm and 99.97 ± 0.13). Incorporation of the hydrolyzed starch into Promethazine HCl sublingual tablets resulted in formulations with adequate mechanical strength (hardness 3.35 ± 0.05 kg), low friability (0.53 ± 0.04%), rapid disintegration (49.18 ± 0.75 s), and high drug release (96.79 ± 0.13%). These performances were comparable to those of crospovidone and superior to formulations containing native pumpkin starch. The improved tablet characteristics were primarily attributed to enhanced porosity and swelling capacity induced by acid hydrolysis. Overall, optimized hydrolyzed pumpkin starch demonstrates considerable potential as a sustainable, biodegradable, and cost-effective natural superdisintegrant for fast-disintegrating pharmaceutical tablet formulations.
EVALUASI SIFAT FISIK SEDIAAN SHAMPO EKSTRAK DAUN KATUK (Sauropus androgynus (L) Merr) DENGAN BERBAGAI VARIASI VISCOSITY AGENT Rashati, Dewi; Eryani, Mikhania Christiningtyas
Jurnal Riset Kefarmasian Indonesia Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v1i1.6

Abstract

Sauropus androgynus (L) Merr leaf in Indonesia called katuk have strong antioxidant activity with IC50 80,01 ppm. The aims of this research is want to know physical properties of katuk leaf shampo which is formulated in various formulas. In this research katuk was formulated in shampoo with viscocity agent (HPMC, sodium CMC and Carbopol) in various concentration. The result showed that all shampoo formulas had low jasmine smell, but had different in form and colour. Shampoo viscocity increased with increased viscocity agent. The highest viscocity showed by F7 with 0,5% carbopol concentration. pH test showed that the shampoo with HPMC and sodium CMC had pH value 6. pH value of shampoo with carbopol was 5. All of pH formulas meet the requirement of SNI standard. Statistical result showed that the physical properties of foam high, viscocity and pH all formulas had significant difference.
Co-Authors AA Sudharmawan, AA Adelia Firandi Adi Prayitno Adifa, Wildan Hanifatul Aditama, Agnis Agnis Pondineka Ria Aditama Amaliyah Nurul Hidayah Ameliana, Lidya Anies Rohman anies Rohman Dwijayanti Ardian Baitariza, Ardian Asa Falahi Asa Falahi Asa Falahi Asa Falahi Ayuk Lestari Ayuning Trias, Diah Azizah Azizah Azizah Azizah Azizah, Fatiya Balqis, Aura Inzalna Barikah, Kuni Zu’aimah Budianto, Muhamad Oke Budipratiwi Wisudyaningsih Choiroh, Afifahtul Claudia Fortunata, Florensia Grace Denok Risky Ayu Paramita Dewi Isadiartuti Dewi Rashati Dewi Rashati Dewi Riskha Nurmalasari Dinar Rizqika Fauza Dyan Maulani Eka Deddy Irawan Eka Yulia Agustin Erika Herawati, Irma Fachry Abda El Rahman Faisal Akhmal Muslikh Hadi Barru Hakam Fajar Siddiq Hadisoebroto, Ginayanti Hanif, Mohammad Ainul Fakhruddin Helmy Yusuf Hery Diar Febryanto Hery Febrianto Ika Norcahyanti Januarti, Melinda Judy Handojo, Kukuh Kukuh Judy Handojo Kuni Barikah Kusumawardani, Arine Giovani Lestari, Tirtawati Putri Lina Winarti Lubis, Maralodia Almira Lusia Oktora Ruma Kumala Sari Mardani, Alya Eka Dhyra Mayang Kusuma Dewi Melinda Januarti Muhammad Asrofi, Muhammad Muthi'atul, Bannan Muzayanah, Arifatul Nina Wijiani Nina Wijiani Ningsih, Anita Dwi Rahayu Noer Layla Fitri Ani Norisca Aliza Putriana Nur Patihul Patihul Husni Permatasari, Lina Putri perwita, tista rashati Dewi Rashati, Dewi Rina Haryani Rini Silviya Risma Khoiro Safitri Ryad Alati Safitri, Manzil Saleh Wikarsa Sari, Lusia Siti Nur Azizah Siti Nur Azizah, Siti Nur Siti Rohmah Fadilah Soemirtapura, Yeyet Cahyati Suryaningsih, Farida Syuhuriah, Ainin Tanfidz Alishlah, Tanfidz Tasya, Pradiva Julias Tryani Sutisna Putri, Sussy Uswatul Hasanah Viddy Agustian Rosyidi Wahyuni, Ela Wardhani, Firdha Aprillia Yeyet Cahyati Soemirtapura Yudi Wicaksono Zulvania, Clarissa Najwa