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All Journal Jurnal Bios Logos Indonesian Journal of Medicine Jurnal Ilmu Kefarmasian Indonesia Jurnal Ners Multidiciplinary Output Research for Actual and International Issue (Morfai Journal) Jurnal Pengabdian Pada Masyarakat METHABDI Majalah Ilmiah METHODA Jurnal Kefarmasian Indonesia Cermin Dunia Kedokteran Jurnal Kedokteran Methodist Indonesian Journal of Global Health Research
Endy Juli Anto
Universitas Methodist Indonesia
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Edukasi Kesehatan Prostat untuk Meningkatkan Kesadaran Deteksi Dini pada Jemaat GMI Manna Helvetia Medan Anto, Endy Juli; Siahaan, Jekson Martiar; Fauzi, Tengku M.; Normi, Siti; Panjaitan, Maludin; Hutapea, Kenal P.; Panataria, Lince Romauli; Simanjuntak, Pantas; Sihombing, Parsaoran; Saragih, Meylin Kristina; Manurung, Agnes Imelda; Sitorus, Efbertias; Sitorus, Ragnar Oktavianus; Simatupang, Jones T.; Nababan, Manaor Bismar Posman; Simatupang, Aditia Erick Cantona; Sirait, Kilian; Silalahi, Veraci
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 4 No 2 (2024): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol4No2.pp215-218

Abstract

Prostate disease is a significant health concern affecting men, particularly those over 35 years old. This community service activity aimed to increase knowledge and awareness about prostate disease among the congregation of GMI Manna Helvetia Medan through health education. The methods included educational presentations, motivational sessions, and question-and-answer discussions. The activity was attended by 45 participants aged 35-70 years. Results showed improved participant understanding of prostate disease symptoms, risk factors, and the importance of early detection. About 70% of participants committed to undergo prostate examination within the next 6 months. The educational approach through church community proved effective in delivering sensitive health information and raising awareness about the importance of regular check-ups.
Pelatihan Penanganan Cardiac Arrest (Henti Jantung) dengan Menggunakan Metode Bantuan Hidup Dasar (BHD) Bagi Pengemudi Ojek Online Se Kota Medan Siahaan, Dwi Lunarta D. S.; Sinatra, Jadeny; Nazma, Diani; Lubis, Andriamuri P.; Tanjung, Qodri F.; Sitepu, John Frans; Hamdi, Tasrif; Hamdani, Irfan; Chalil, M. Jalaluddin A.; Yunafri, Andri; Irina, Sinta; Zainumi, Cut M.; Fadinie, Wulan; Silaen, Ester L. R.; Simbolon, Boyke M.; Siahaan, Jekson M.; Lim, Hadyanto; Anto, Endy Juli; Tobing, Paul S. M. L.; Rimbun, Surjadi; Hutasoit, Eka Samuel P.; Tambunan, Ronald T. H.; Tarigan, Juliyanti; Stephanie S., Kezia; Natalie S., Karen
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 4 No 2 (2024): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol4No2.pp188-193

Abstract

Cardiac Arrest is the leading cause of death in the world including Indonesia, which can occur anytime and anywhere. The causes vary, ranging from fatigue, and underlying health conditions, to traffic accidents. Basic Life Support (BLS) is the initial step that can be taken to restore respiratory and circulatory function in individuals experiencing respiratory or cardiac arrest. It is important for online motorcycle taxi drivers to possess these skills, as they often spend time on the road and interact with various people in different situations. Perhimpunan Dokter Spesialis Anesthesiology dan Terapi Intensif (PERDATIN) North Sumatra Branch concluded a series of Kursus Penyegar dan Penambah Ilmu Anestesia (KPPIA) by providing basic life support training to 521 public transport or online motorcycle taxi drivers in the city of Medan on September 29, 2024. Held at the Gedung Serba Guna of the North Sumatra Provincial Government, the participants were divided into 52 groups guided directly by anesthesiologist specialists as instructors. By providing this education and training, they can be better prepared to face emergency situations on the road, thereby enhancing safety and service for passengers
Manfaat Citicoline pada Tata Laksana Stroke Iskemik Juli Anto, Endy; Siahaan, Jekson Martiar; Eyanoer, Putri Chairani
Cermin Dunia Kedokteran Vol 51 No 5 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i5.1056

Abstract

Background: Stroke is the third most common disease after heart disease and cancer and the main cause of disability worldwide. The most common type of stroke, which accounts for around 85%-87% of cases, is ischemic stroke (IS). This report is to examine the benefits of citicoline for IS patients. Case: A 63-year-old male was admitted with a diagnosis of IS and electrolyte disturbances. General treatment is semi-Fowler’s position, oxygen, and maintaining fluid and nutritional intake. Specific management is RL infusion 20 gtt/minute, candesartan 1x16 mg, clopidogrel 1x75 mg, omeprazole 40 mg/24 h intravenous (IV), and citicoline 500 mg/12 h IV. The patient showed clinical improvement. Method: Articles in PubMed, Cochrane, and Google Scholar in February-April 2022 were searched to find relevant studies to be evaluated with inclusion and exclusion criteria. The full text was obtained and critically reviewed with the evidence-based medicine guidelines. The results are limited to systematic reviews and meta-analyses. Results: Five studies were deemed valid, important, and applicable. However, the quality of these studies varies. Conclusion: All studies show that citicoline use could potentially improve clinical outcomes in IS patients.
HUBUNGAN GAMBARAN CT-SCAN PARU DENGAN KADAR LIMFOSIT DAN NEUTROFIL PADA PASIEN SARS-COV-2 PADA PERIODE JUNI, JULI, DAN AGUSTUS TAHUN 2021 DI RUMAH SAKIT UMUM VINA ESTETICA MEDAN Tampubolon, Benny; Anto, Endy Juli; Girsang, Elizabeth
Jurnal Kedokteran Methodist Vol. 15 No. 2 (2022): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

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Abstract

Background : Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of Coronavirus that is transmitted to humans that attacks the respiratory system and manifests as inflammation of the lung parenchyma. CT-Scan can be used as an alternative diagnostic measure to find out the radiological picture of COVID-19 patients. Neutrophils are present in many acute respiratory distress syndrome (ARDS)-associated lung diseases, as influenza virus and SARS-CoV-1 infection. Neutrophil activation and degranulation occur in SARS infection. The immune response that occurs in COVID-19 patients with severe clinical trials can be found in lower lymphocyte counts. Decreases in helper T cells, suppressor T cells, and regulatory T cells are found in patients with COVID-19, with higher levels of T helper and regulatory T cells. low in severe cases. Research Objectives: To find out whether there is a relationship between CT-Scan Lung images and Lymphocyte and Neutrophil Levels in SARS-CoV-2 Patients, Research Methods: The type of research carried out is observational analytic measurement, with a cross sectional design the researcher makes observations or measurements of variables at certain times. Results: The frequency distribution on CT-Scan images of the lungs of SARS-CoV-2 patients was found to be the most GGO accompanied by infiltrates with a frequency of 22 people (38.6%) and the frequency distribution of Lymphocyte and Neutrophil levels in SARS-CoV-2 patients. The highest number of lymphocytes in patients with SARS-CoV-2 was normal with a frequency of 27 people (47.4%) and Neutrophil levels increased with a frequency of 24 people (42.1%). In the analysis there was a significant relationship between CT-Scan images of the lungs and lymphocyte levels, p-values = 0.013 and in Neutrophils with CT-Scan images of lungs of SARS-CoV-2 patients, there was no significant relationship with p-values = 0.092 Conclusion:There is a relationship between the CT-Scan images of the lungs of SARS-CoV-2 patients and the levels of lymphocytes and there is no relationship between the CT-Scan images of the lungs of SARS-CoV-2 patients and the levels of neutrophils in the body.
Hubungan gambaran CT-Scan paru dengan kadar monosit dan laju endap darah pada pasien SARS-COV-2. Novianti, Wulan; Anto, Endy Juli; B. Hutagalung , Sanggam
Jurnal Kedokteran Methodist Vol. 15 No. 2 (2022): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

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Abstract

Background : Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of Coronavirus that is transmitted to humans that attacks the respiratory system and manifests as inflammation of the lung parenchyma. CT Scan can be used as an alternative diagnostic measure to find out the radiological picture of COVID19 patients. monocytes/macrophages can serve as reservoirs which, consequently, will serve as vectors of virus spread to other tissues, but this has not been proven in SARS-CoV-2. Inflammation is an important body mechanism to protect itself from foreign objects. During this process, cells release various proinflammatory cytotoxins, including active-phase proteins such as CRP (C-Reactive Protein) and fibrinogen. Then, the increase in fibrinogen levels further becomes a factor that increases the ESR. Research Objectives: To determine whether there is a relationship between CTScan Lung images and Monocyte Levels and ESR in SARS-CoV-2 patients. Research Methods: The type of research carried out is observational analytic measurement, with a cross sectional design the researcher makes observations or measurements of variables at certain times. Research results: the frequency distribution on CT-SCAN images of the lungs of SARS-CoV-2 patients was found to be the most GGO with a frequency of 22 people (38.6%) and the frequency distribution of monocyte and ESR levels in SARS-CoV2 patients obtained the highest levels of monocytes. in patients with SARS-CoV-2 is normal with a frequency of 35 people (61.4%) and the ESR level is normal with a frequency of 44 people (77.2%). In the analysis, there was a significant relationship between pulmonary CT-SCAN images on monocyte levels and ESR in patients with SARS-CoV-2 p-values = 0.022 and 0.003, and had a simultaneous and partial effect. Conclusion: there is a relationship between CT-SCAN images of the lungs of SARSCoV-2 patients and the levels of monocytes and ESR in the body.
A Case of Complete Recovery From Recurrent Bell’s Palsy After Peripheral Blood Stem Cell Transplantation : A Case of Complete Recovery From Recurrent Bell’s Palsy After Peripheral Blood Stem Cell Transplantation lim, hadyanto; Hutasoit, Eka Samuel P; Endy Juli Anto
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

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Abstract

Background Recurrent Bell’s palsy is a rare condition that can affect the ipsilateral or contralateral to the affected side of the primary attack. There is still no consensus on treatment guidelines for recurrent Bell’s palsy. Therefore, we report a case of idiopathic recurrent contralateral facial palsy treated with autologous peripheral blood stem cell (PBSC) transplantation. Case Presentation A 72-year-old man presented with the sudden onset of right facial weakness, which was contralateral to the affected side of the first episode of facial palsy. The weakness had progressed with difficulty in closing the right eye, drooling the water from the right side of the mouth, and chewing impairment which was consistent with House Brackmann grade IV or moderately severe facial nerve grading system. He had exposure to cold stimulation, and a history of hypertension. He was given G-CSF 10 ug/kg/day for 5 days to mobilize stem cells, followed by apheresis on the 5th day. He did not receive acupuncture treatment. He had a complete recovery in 3 weeks with House Brackmann grade I or normal function of facial nerve. Conclusion Peripheral blood stem cell transplantation had a beneficial effect on the complete recovery of this recurrent Bell’s palsy and provides a treatment strategy in patients with unilateral facial palsy.
Setetes Darah, Sejuta Kasih dan Harapan: Kegiatan Donor Darah Sukarela oleh Lions Club Medan Angkasa untuk Meningkatkan Ketersediaan Stok Darah di Medan Anto, Endy Juli; Tim Lions Club Medan Angkasa; Tambunan, Ronald T. H.; Manullang, Frengky S.; Tiji, Wijaya Taufik; Fauzi, Tengku M.; Sinatra, Jadeny; Jamnasi, Juli; Siahaan, Jekson Martiar
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 5 No 1 (2025): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

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Abstract

Blood donation is a critical healthcare activity that saves millions of lives worldwide. This community service activity aimed to increase blood stock availability and raise awareness about voluntary blood donation through Lions Club Medan Angkasa's initiative "Setetes Darah, Sejuta Kasih dan Harapan" (A Drop of Blood, Million Love and Hope). The blood donation drive was conducted on November 26, 2023, at Manhattan Times Square 3rd floor, Medan. The activity included health screening, blood collection, and educational sessions about the importance of regular blood donation. A total of 150 voluntary donors participated in the event, successfully collecting 135 bags of blood (340cc each) after medical screening. The results showed high community participation and awareness about the importance of blood donation. This initiative demonstrates the effectiveness of community-based organizations in supporting healthcare systems and promoting voluntary blood donation culture in society.
Bakti Sosial Operasi Katarak dalam Meningkatkan Fungsi Penglihatan dan Produktivitas Masyarakat Kurang Mampu di Tebing Tinggi Sucipto, Sucipto; Anto, Endy Juli; Ronald T. H. Tambunan; Frengky S. Manullang; Widjaya Taufik Tiji; Tengku M. Fauzi; Jadeny Sinatra; Juli Jamnasi; Jekson Martiar Siahaan
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 5 No 2 (2025): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

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Abstract

Cataract is the leading cause of blindness worldwide and a major public health challenge, particularly among underserved populations in Indonesia. This community service activity aimed to restore vision and improve quality of life for underprivileged cataract patients through free cataract surgery provided by Lions Club Medan Angkasa and Lions Club Tebing Tinggi Royal in collaboration with Tebing Tinggi Police Department and Bhayangkara Hospital. The surgical camp was conducted on Sunday, April 27, 2025, at RS Bhayangkara Tebing Tinggi, in commemoration of the 79th Bhayangkara Anniversary. The activity included pre-operative screening, phacoemulsification cataract surgery, pterygium excision, and post-operative care. A total of 79 patients participated: 73 cataract cases and 6 pterygium cases. All surgeries were performed successfully by experienced ophthalmologists using modern surgical techniques. Post-operative evaluation showed significant visual improvement in 98% of patients. This initiative demonstrates the effectiveness of multi-sector collaboration in addressing preventable blindness and highlights the crucial role of community-based organizations in supporting healthcare access for marginalized populations.
Peran Lutein dan Zeaxanthin dalam Formulasi AREDS 2: Mekanisme Protektif dan Implementasi Klinis pada Age-Related Macular Degeneration: Tinjauan Pustaka Endy Juli Anto; Rusli, Kenvin
Cermin Dunia Kedokteran Vol 53 No 04 (2026): April 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i04.2134

Abstract

Lutein and zeaxanthin are carotenoids that serve as key components in the Age-Related Eye Disease Study 2 (AREDS 2) formulation, replacing beta-carotene from the original formulation due to safety concerns. These carotenoids exhibit dual protective mechanisms as blue light filters and antioxidants within the macula. This literature review aims to analyze the specific roles of lutein and zeaxanthin in AREDS 2, their molecular protective mechanisms, and their optimal clinical implementation in age-related macular degeneration (AMD). Literature searches were conducted through PubMed, Cochrane Library, and Google Scholar using the keywords "lutein", "zeaxanthin", "AREDS 2","macular pigment", and "photoprotection". Lutein and zeaxanthin selectively accumulate in the macula, forming macular pigment optical density (MPOD), which functions as blue light filter (400–500 nm) and free radical scavenger. Supplementation with lutein 10 mg and zeaxanthin 2 mg in AREDS 2 has been proven to increase MPOD and reduce the risk of age-related macular degeneration (AMD) progression by 10%–26%. Clinical implementation requires baseline MPOD evaluation, individualized response monitoring, and dose optimization based on nutritional status and patient-specific risk factors.
Anti-inflammatory and Insulin-sensitizing Effects of Combined Pandanus amaryllifolius and Syzygium polyanthum Extracts in HFD-STZ Induced Diabetic Rats Meilinda, Selvia; Lim, Hadyanto; Anto, Endy Juli; Siahaan, Jekson M; Tarigan, Menang B
JURNAL BIOS LOGOS Vol. 16 No. 1 (2026): JURNAL BIOS LOGOS
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jbl.v16i1.66731

Abstract

Type 2 Diabetes Mellitus (T2DM) is a global health crisis characterized by insulin resistance and pancreatic -cell failure, largely driven by chronic low-grade inflammation. Elevated pro-inflammatory markers, particularly TNF- and IL-6, disrupt insulin signaling. While conventional oral hypoglycemics are effective, their long-term use is often hindered by adverse effects. Pandanus amaryllifolius and Syzygium polyanthum are polyphenol-rich medicinal plants with significant antioxidant potential. This study evaluates the in vivo efficacy of a combined ethanolic extract of these plants in reducing TNF-, IL-6, and HOMA-IR levels, alongside in silico validation of their bioactive compounds. An experimental posttest-only control group design was employed using HFD-STZ-induced male Wistar rats. Key parameters included blood glucose, HOMA-IR, inflammatory cytokines, and pancreatic histopathology. Molecular docking was conducted to analyze the interaction between bioactive compounds and glucose metabolism receptors. The combined extracts significantly suppressed systemic inflammation, marked by a substantial reduction in TNF- and IL-6. This correlated with improved insulin sensitivity and lower HOMA-IR values. Histopathologically, the 200 mg/kg BW dose showed the most significant recovery of the islets of Langerhans. In silico analysis confirmed that flavonoids like quercetin exhibit strong binding affinities to target proteins. The combination of P. amaryllifolius and S. polyanthum acts as a potent anti-inflammatory and insulin sensitizer, offering a promising adjuvant therapy for T2DM management.
Co-Authors Agnes Imelda Manurung Alex M. Lumbanraja Alexander P. Marpaung Anjany, Larasaty Ardinata, Dedi - Atta Celine Nouli Saruksuk B. Hutagalung , Sanggam Binarwan Halim Binarwan Halim Caroline Koswara Chalil, M. Jalaluddin A. Dearni Damanik Depari, A. A. Diani Nazma Dina Keumala Sari Dina R. Purba Dwi L. D. S. Siahaan Dwi Lunarta Doderina Siahaan Efbertias Sitorus Eka Samuel P Hutasoit Elizabeth Septianur Girsang Enney Evirosa J. Simanjuntak Fadinie, Wulan Faskanita M. Nadapdap Fauzi, Tengku M. Fauzi, Tengku Muhammad Frengky S. Manullang Frengky S. Manullang Gani, Endang Haryanti Girsang, Elizabeth Girsang, Elizabeth Septianur Grace Stefani Christanto Hadyanto L Hadyanto Lim Hakim, Enggrek Pelita Hamdi, Tasrif Helmida Gultom Hutapea, Kenal P. Hutasoit, Eka Samuel P Hutasoit, Eka Samuel P Hutasoit, Eka Samuel P. Ilyas, Syaffrudin Inda M. Sinaga Irene Ruminta Tua Damanik Irfan Hamdani, Irfan Irina, Sinta Ivonne R. V. O Situmeang Ivonne Ruth Vitamaya Oishi Situmeang Jadeny Sinarta Jadeny Sinatra Jadeny Sinatra Jeffrey Jerry Tobing Jimmy Jimmy Jones Simatupang Juli Jamnasi Juli Jamnasi Juli Jamnasi Juliyanti Juliyanti Kembaren, Alfri Yoganta S. Laura P. S. Tambunan Lubis, Andriamuri P. Maludin Panjaitan Manik, Widya Dayanti Feronika Manullang, Frengky S. Manullang, Frenky Sorimuda Mei Jayanti Siregar Meilinda, Selvia Melissa Angie Mira Mustika Momot, Estela Salomina Nababan, Manaor Bismar Posman Natalie S., Karen Novianti, Wulan Noviyanti, Berliana Noviyanti, Berliana Novrina Situmorang Panataria, Lince Romauli Panjaitan, Bintang Andika Pasaribu, Sumihar Pratiwi, Ade Dwi Putri Chairani Eyanoer Putri Chairani Eyanoer, Putri Chairani Ragnar Octavianus Sitorus Ratih Praseti Yanti Ratna Mega Sary Ria Oktavia Rimbun, Surjadi Ronald T. H. Tambunan Ronald T. H. Tambunan Ronald T. H. Tambunan, Rusli, Kenvin SARAGIH, MEYLIN KRISTINA Sari, Dina Keumala Sembiring, Budi Darmanta Sembiring, Mikael Siahaan, Jekson Martiar Sihaloho, Kerin Repaskatri Sihaloho, Lovian Nauli Sihombing, Parsaoran Sijabat, Kesia Silaen, Ester L. R. Silalahi, Veraci Silangit, Thomas Silitonga, Hendrika A Silitonga, Hendrika A Silitonga, Hendrika Adriana Silitonga, Hendrika Andriana Simanjuntak, Evirosa J. Simanjuntak, Harry C Simanjuntak, Harry C Simanjuntak, Jeremia Simanjuntak, Pantas Simatupang, Aditia Erick Cantona Simbolon, Boyke M. Sinaga, Inda M. Sinatra, Jadeny Sirait, Kilian Sitepu, John Frans Siti Normi Sitompul, Michael Sabatino Situmeang, Ivonne Ruth Vitamaya Oishi Stephanie S., Kezia Steven Tjendra Sucipto Sucipto Sucipto Sucipto Syafruddin Ilyas Syafruddin Ilyas Syafruddin Ilyas Tambunan, Ronald T. H. Tambunan, Ronald Tunggul Hotmarojahan Tampubolon, Benny Tanjung, Qodri F. Tarigan, Juliyanti Tarigan, Menang B Tarigan, Menang Bastanta Tengku M. Fauzi Tengku M. Fauzi Thomas Silangit Tiara Larasati Tiji, Widjaya Taufik Tim Lions Club Medan Angkasa Tim Lions Club Medan Angkasa Tobing, Paul S. M. L. Vivian Vivian Widjaya Taufik Tiji Widjaya Taufik Tiji Wijaya Taufik Tiji Wijaya, Mega YUNAFRI, ANDRI Zainumi, Cut M.