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All Journal Jurnal Bios Logos Indonesian Journal of Medicine Jurnal Ilmu Kefarmasian Indonesia Multidiciplinary Output Research for Actual and International Issue (Morfai Journal) Jurnal Pengabdian Pada Masyarakat METHABDI Majalah Ilmiah METHODA Jurnal Kedokteran Methodist
Endy Juli Anto
Universitas Methodist Indonesia
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Pelatihan Penanganan Cardiac Arrest (Henti Jantung) dengan Menggunakan Metode Bantuan Hidup Dasar (BHD) Bagi Pengemudi Ojek Online Se Kota Medan Siahaan, Dwi Lunarta D. S.; Sinatra, Jadeny; Nazma, Diani; Lubis, Andriamuri P.; Tanjung, Qodri F.; Sitepu, John Frans; Hamdi, Tasrif; Hamdani, Irfan; Chalil, M. Jalaluddin A.; Yunafri, Andri; Irina, Sinta; Zainumi, Cut M.; Fadinie, Wulan; Silaen, Ester L. R.; Simbolon, Boyke M.; Siahaan, Jekson M.; Lim, Hadyanto; Anto, Endy Juli; Tobing, Paul S. M. L.; Rimbun, Surjadi; Hutasoit, Eka Samuel P.; Tambunan, Ronald T. H.; Tarigan, Juliyanti; Stephanie S., Kezia; Natalie S., Karen
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 4 No 2 (2024): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol4No2.pp188-193

Abstract

Cardiac Arrest is the leading cause of death in the world including Indonesia, which can occur anytime and anywhere. The causes vary, ranging from fatigue, and underlying health conditions, to traffic accidents. Basic Life Support (BLS) is the initial step that can be taken to restore respiratory and circulatory function in individuals experiencing respiratory or cardiac arrest. It is important for online motorcycle taxi drivers to possess these skills, as they often spend time on the road and interact with various people in different situations. Perhimpunan Dokter Spesialis Anesthesiology dan Terapi Intensif (PERDATIN) North Sumatra Branch concluded a series of Kursus Penyegar dan Penambah Ilmu Anestesia (KPPIA) by providing basic life support training to 521 public transport or online motorcycle taxi drivers in the city of Medan on September 29, 2024. Held at the Gedung Serba Guna of the North Sumatra Provincial Government, the participants were divided into 52 groups guided directly by anesthesiologist specialists as instructors. By providing this education and training, they can be better prepared to face emergency situations on the road, thereby enhancing safety and service for passengers
HUBUNGAN GAMBARAN CT-SCAN PARU DENGAN KADAR LIMFOSIT DAN NEUTROFIL PADA PASIEN SARS-COV-2 PADA PERIODE JUNI, JULI, DAN AGUSTUS TAHUN 2021 DI RUMAH SAKIT UMUM VINA ESTETICA MEDAN Tampubolon, Benny; Anto, Endy Juli; Girsang, Elizabeth
Jurnal Kedokteran Methodist Vol. 15 No. 2 (2022): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

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Abstract

Background : Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of Coronavirus that is transmitted to humans that attacks the respiratory system and manifests as inflammation of the lung parenchyma. CT-Scan can be used as an alternative diagnostic measure to find out the radiological picture of COVID-19 patients. Neutrophils are present in many acute respiratory distress syndrome (ARDS)-associated lung diseases, as influenza virus and SARS-CoV-1 infection. Neutrophil activation and degranulation occur in SARS infection. The immune response that occurs in COVID-19 patients with severe clinical trials can be found in lower lymphocyte counts. Decreases in helper T cells, suppressor T cells, and regulatory T cells are found in patients with COVID-19, with higher levels of T helper and regulatory T cells. low in severe cases. Research Objectives: To find out whether there is a relationship between CT-Scan Lung images and Lymphocyte and Neutrophil Levels in SARS-CoV-2 Patients, Research Methods: The type of research carried out is observational analytic measurement, with a cross sectional design the researcher makes observations or measurements of variables at certain times. Results: The frequency distribution on CT-Scan images of the lungs of SARS-CoV-2 patients was found to be the most GGO accompanied by infiltrates with a frequency of 22 people (38.6%) and the frequency distribution of Lymphocyte and Neutrophil levels in SARS-CoV-2 patients. The highest number of lymphocytes in patients with SARS-CoV-2 was normal with a frequency of 27 people (47.4%) and Neutrophil levels increased with a frequency of 24 people (42.1%). In the analysis there was a significant relationship between CT-Scan images of the lungs and lymphocyte levels, p-values = 0.013 and in Neutrophils with CT-Scan images of lungs of SARS-CoV-2 patients, there was no significant relationship with p-values = 0.092 Conclusion:There is a relationship between the CT-Scan images of the lungs of SARS-CoV-2 patients and the levels of lymphocytes and there is no relationship between the CT-Scan images of the lungs of SARS-CoV-2 patients and the levels of neutrophils in the body.
Hubungan gambaran CT-Scan paru dengan kadar monosit dan laju endap darah pada pasien SARS-COV-2. Novianti, Wulan; Anto, Endy Juli; B. Hutagalung , Sanggam
Jurnal Kedokteran Methodist Vol. 15 No. 2 (2022): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

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Abstract

Background : Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of Coronavirus that is transmitted to humans that attacks the respiratory system and manifests as inflammation of the lung parenchyma. CT Scan can be used as an alternative diagnostic measure to find out the radiological picture of COVID19 patients. monocytes/macrophages can serve as reservoirs which, consequently, will serve as vectors of virus spread to other tissues, but this has not been proven in SARS-CoV-2. Inflammation is an important body mechanism to protect itself from foreign objects. During this process, cells release various proinflammatory cytotoxins, including active-phase proteins such as CRP (C-Reactive Protein) and fibrinogen. Then, the increase in fibrinogen levels further becomes a factor that increases the ESR. Research Objectives: To determine whether there is a relationship between CTScan Lung images and Monocyte Levels and ESR in SARS-CoV-2 patients. Research Methods: The type of research carried out is observational analytic measurement, with a cross sectional design the researcher makes observations or measurements of variables at certain times. Research results: the frequency distribution on CT-SCAN images of the lungs of SARS-CoV-2 patients was found to be the most GGO with a frequency of 22 people (38.6%) and the frequency distribution of monocyte and ESR levels in SARS-CoV2 patients obtained the highest levels of monocytes. in patients with SARS-CoV-2 is normal with a frequency of 35 people (61.4%) and the ESR level is normal with a frequency of 44 people (77.2%). In the analysis, there was a significant relationship between pulmonary CT-SCAN images on monocyte levels and ESR in patients with SARS-CoV-2 p-values = 0.022 and 0.003, and had a simultaneous and partial effect. Conclusion: there is a relationship between CT-SCAN images of the lungs of SARSCoV-2 patients and the levels of monocytes and ESR in the body.
Setetes Darah, Sejuta Kasih dan Harapan: Kegiatan Donor Darah Sukarela oleh Lions Club Medan Angkasa untuk Meningkatkan Ketersediaan Stok Darah di Medan Anto, Endy Juli; Tim Lions Club Medan Angkasa; Tambunan, Ronald T. H.; Manullang, Frengky S.; Tiji, Wijaya Taufik; Fauzi, Tengku M.; Sinatra, Jadeny; Jamnasi, Juli; Siahaan, Jekson Martiar
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 5 No 1 (2025): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

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Abstract

Blood donation is a critical healthcare activity that saves millions of lives worldwide. This community service activity aimed to increase blood stock availability and raise awareness about voluntary blood donation through Lions Club Medan Angkasa's initiative "Setetes Darah, Sejuta Kasih dan Harapan" (A Drop of Blood, Million Love and Hope). The blood donation drive was conducted on November 26, 2023, at Manhattan Times Square 3rd floor, Medan. The activity included health screening, blood collection, and educational sessions about the importance of regular blood donation. A total of 150 voluntary donors participated in the event, successfully collecting 135 bags of blood (340cc each) after medical screening. The results showed high community participation and awareness about the importance of blood donation. This initiative demonstrates the effectiveness of community-based organizations in supporting healthcare systems and promoting voluntary blood donation culture in society.
Bakti Sosial Operasi Katarak dalam Meningkatkan Fungsi Penglihatan dan Produktivitas Masyarakat Kurang Mampu di Tebing Tinggi Sucipto, Sucipto; Anto, Endy Juli; Ronald T. H. Tambunan; Frengky S. Manullang; Widjaya Taufik Tiji; Tengku M. Fauzi; Jadeny Sinatra; Juli Jamnasi; Jekson Martiar Siahaan
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 5 No 2 (2025): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

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Abstract

Cataract is the leading cause of blindness worldwide and a major public health challenge, particularly among underserved populations in Indonesia. This community service activity aimed to restore vision and improve quality of life for underprivileged cataract patients through free cataract surgery provided by Lions Club Medan Angkasa and Lions Club Tebing Tinggi Royal in collaboration with Tebing Tinggi Police Department and Bhayangkara Hospital. The surgical camp was conducted on Sunday, April 27, 2025, at RS Bhayangkara Tebing Tinggi, in commemoration of the 79th Bhayangkara Anniversary. The activity included pre-operative screening, phacoemulsification cataract surgery, pterygium excision, and post-operative care. A total of 79 patients participated: 73 cataract cases and 6 pterygium cases. All surgeries were performed successfully by experienced ophthalmologists using modern surgical techniques. Post-operative evaluation showed significant visual improvement in 98% of patients. This initiative demonstrates the effectiveness of multi-sector collaboration in addressing preventable blindness and highlights the crucial role of community-based organizations in supporting healthcare access for marginalized populations.
Bakti Sosial Operasi Katarak dalam Meningkatkan Fungsi Penglihatan dan Produktivitas Masyarakat Kurang Mampu di Tebing Tinggi Sucipto, Sucipto; Anto, Endy Juli; Ronald T. H. Tambunan; Frengky S. Manullang; Widjaya Taufik Tiji; Tengku M. Fauzi; Jadeny Sinatra; Juli Jamnasi; Jekson Martiar Siahaan
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 5 No 2 (2025): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol5No2.pp170-178

Abstract

Cataracts are the leading cause of blindness worldwide and a major public health challenge, particularly among underserved populations in Indonesia. This community service activity aimed to restore vision and improve quality of life for underprivileged cataract patients through free cataract surgery provided by Lions Club Medan Angkasa and Lions Club Tebing Tinggi Royal in collaboration with Tebing Tinggi Police Department and Bhayangkara Hospital. The surgical camp was conducted on Sunday, April 27, 2025, at RS Bhayangkara Tebing Tinggi, in commemoration of the 79th Bhayangkara Anniversary. The activity included preoperative screening, phacoemulsification cataract surgery, pterygium excision, and postoperative care. A total of 79 patients participated: 73 cataract cases and 6 pterygium cases. Experienced ophthalmologists successfully performed all surgeries using modern surgical techniques. Post-operative evaluation showed significant visual improvement in 98% of patients. This initiative demonstrates the effectiveness of multi-sector collaboration in addressing preventable blindness and highlights the crucial role of community-based organizations in supporting healthcare access for marginalized populations.
Anti-inflammatory and Insulin-sensitizing Effects of Combined Pandanus amaryllifolius and Syzygium polyanthum Extracts in HFD-STZ Induced Diabetic Rats Meilinda, Selvia; Lim, Hadyanto; Anto, Endy Juli; Siahaan, Jekson M; Tarigan, Menang B
JURNAL BIOS LOGOS Vol. 16 No. 1 (2026): JURNAL BIOS LOGOS
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jbl.v16i1.66731

Abstract

Type 2 Diabetes Mellitus (T2DM) is a global health crisis characterized by insulin resistance and pancreatic -cell failure, largely driven by chronic low-grade inflammation. Elevated pro-inflammatory markers, particularly TNF- and IL-6, disrupt insulin signaling. While conventional oral hypoglycemics are effective, their long-term use is often hindered by adverse effects. Pandanus amaryllifolius and Syzygium polyanthum are polyphenol-rich medicinal plants with significant antioxidant potential. This study evaluates the in vivo efficacy of a combined ethanolic extract of these plants in reducing TNF-, IL-6, and HOMA-IR levels, alongside in silico validation of their bioactive compounds. An experimental posttest-only control group design was employed using HFD-STZ-induced male Wistar rats. Key parameters included blood glucose, HOMA-IR, inflammatory cytokines, and pancreatic histopathology. Molecular docking was conducted to analyze the interaction between bioactive compounds and glucose metabolism receptors. The combined extracts significantly suppressed systemic inflammation, marked by a substantial reduction in TNF- and IL-6. This correlated with improved insulin sensitivity and lower HOMA-IR values. Histopathologically, the 200 mg/kg BW dose showed the most significant recovery of the islets of Langerhans. In silico analysis confirmed that flavonoids like quercetin exhibit strong binding affinities to target proteins. The combination of P. amaryllifolius and S. polyanthum acts as a potent anti-inflammatory and insulin sensitizer, offering a promising adjuvant therapy for T2DM management.
ANTI-MELANOGENIC PROPERTIES OF CELERY LEAF EXTRACT IN HYPERPIGMENTATION INDUCED BY AZIDOTHYMIDINE Dearni Damanik; Jekson M. Siahaan; Endy Juli Anto; Syafruddin Ilyas; Hadyanto L
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 6 No. 3 (2026): Multidiciplinary Output Research For Actual and International Issue
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.20682914

Abstract

The purpose of this study is to examine the impact of ethanolic extract form Celery leaves (Apium graveolens L.) on hyperpigmented Wistar rats (Rattus norvegicus sp.) induced by Azidothymidine (AZT). Celery leaves are known to contain bioactive compounds which may serve as potent anti-inflammatory and antioxidant agents. About 30 male Wistar rats were divided into five groups, including a positive control, a negative control, and groups treated with various doses (1%, 3% and 5%) of celery leaf extract. The study examined inflammation indicators such as MDA, TNF-α, and IL-6. Celery leaf extract significantly (P<0.001) reduced MDA, TNF-α, and IL-6 levels in rats, demonstrating its capacity to attenuate inflammation and oxidative stress produced by AZT. With the increase in celery leaf extract concentration from 1% to 5%, MDA, IL-6 and TNF-α levels decreased from 42.083 ± 3.49 to 28.277 ± 10.27 nmol/ml, 14.588 ± 3.38 to 4.539 ± 1.40 nmol/ml and 667.614 ± 143.41 to 326.920 ± 62.72 nmol/ml respectively. Histopathological examinations demonstrated improvements in skin tissues damaged by inflammation. The results indicate that an ethanol extract of celery leaves has the potential to be an efficient anti-inflammatory drug, notably in lowering AZT-induced inflammation and hyperpigmentation. Further research is required to explore its clinical applicability in controlling inflammatory diseases in human.
Co-Authors Agnes Imelda Manurung Alex M. Lumbanraja Alexander P. Marpaung Anjany, Larasaty Ardinata, Dedi - B. Hutagalung , Sanggam Caroline Koswara Chalil, M. Jalaluddin A. Dearni Damanik Depari, A. A. Diani Nazma Dina Keumala Sari Dwi L. D. S. Siahaan Efbertias Sitorus Elizabeth Septianur Girsang Evirosa J. Simanjuntak Fadinie, Wulan Faskanita M. Nadapdap Fauzi, Tengku M. Fauzi, Tengku Muhammad Frengky S. Manullang Frengky S. Manullang Gani, Endang Haryanti Girsang, Elizabeth Girsang, Elizabeth Septianur Hadyanto L Hadyanto Lim Hakim, Enggrek Pelita Hamdi, Tasrif Helmida Gultom Hutapea, Kenal P. Hutasoit, Eka Samuel P Hutasoit, Eka Samuel P Hutasoit, Eka Samuel P. Ilyas, Syaffrudin Inda M. Sinaga Irfan Hamdani, Irfan Irina, Sinta Ivonne R. V. O Situmeang Ivonne Ruth Vitamaya Oishi Situmeang Jadeny Sinatra Jadeny Sinatra Jeffrey Jekson M. Siahaan Jerry Tobing Jimmy Jimmy Jones Simatupang Juli Jamnasi Juli Jamnasi Juliyanti Juliyanti Kembaren, Alfri Yoganta S. Laura P. S. Tambunan Lubis, Andriamuri P. Maludin Panjaitan Manik, Widya Dayanti Feronika Manullang, Frengky S. Manullang, Frenky Sorimuda Meilinda, Selvia Momot, Estela Salomina Nababan, Manaor Bismar Posman Natalie S., Karen Novianti, Wulan Noviyanti, Berliana Noviyanti, Berliana Novrina Situmorang Panataria, Lince Romauli Panjaitan, Bintang Andika Pasaribu, Sumihar Pratiwi, Ade Dwi Putri Chairani Eyanoer, Putri Chairani Ria Oktavia Rimbun, Surjadi Ronald T. H. Tambunan SARAGIH, MEYLIN KRISTINA Sari, Dina Keumala Sembiring, Budi Darmanta Sembiring, Mikael Siahaan, Dwi Lunarta D. S. Siahaan, Jekson M Siahaan, Jekson Martiar Sihaloho, Kerin Repaskatri Sihaloho, Lovian Nauli Sihombing, Parsaoran Sijabat, Kesia Silaen, Ester L. R. Silalahi, Veraci Silangit, Thomas Silitonga, Hendrika A Silitonga, Hendrika A Silitonga, Hendrika Adriana Silitonga, Hendrika Andriana Simanjuntak, Evirosa J. Simanjuntak, Harry C Simanjuntak, Harry C Simanjuntak, Jeremia Simanjuntak, Pantas Simatupang, Aditia Erick Cantona Simbolon, Boyke M. Sinaga, Inda M. Sinatra, Jadeny Sirait, Kilian Sitepu, John Frans Siti Normi, Siti Sitompul, Michael Sabatino Sitorus, Ragnar Oktavianus Situmeang, Ivonne Ruth Vitamaya Oishi Situmorang, Novrina Stephanie S., Kezia Sucipto Sucipto Syafruddin Ilyas Tambunan, Ronald T. H. Tambunan, Ronald Tunggul Hotmarojahan Tampubolon, Benny Tanjung, Qodri F. Tarigan, Juliyanti Tarigan, Menang B Tarigan, Menang Bastanta Tengku M. Fauzi Thomas Silangit Tiji, Widjaya Taufik Tiji, Wijaya Taufik Tim Lions Club Medan Angkasa Tobing, Paul S. M. L. Vivian Vivian Widjaya Taufik Tiji Widjaya Taufik Tiji Wijaya, Mega YUNAFRI, ANDRI Zainumi, Cut M.