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All Journal International Journal of Public Health Science (IJPHS) Jurnal Gizi dan Pangan Saintek Perikanan : Indonesian Journal of Fisheries Science and Technology JURNAL GIZI INDONESIA Journal of Nutrition College Jurnal Kesehatan Masyarakat Journal of Biomedicine and Translational Research Indonesian Journal of Human Nutrition agriTECH Mutiara Medika: Jurnal Kedokteran dan Kesehatan Jurnal Media Gizi Indonesia (MGI) Warta IHP (Warta Industri Hasil Pertanian) Medical Laboratory Technology Journal GIZI INDONESIA Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Syntax Literate: Jurnal Ilmiah Indonesia Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology AcTion: Aceh Nutrition Journal Jurnal Gizi Klinik Indonesia Indonesian Food Science and TechnologyJournal Jurnal Aplikasi Teknologi Pangan Amerta Nutrition Canrea Journal: Food Technology, Nutritions, and Culinary Journal JURNAL GIZI DAN KESEHATAN Journal of Telenursing (JOTING) Jurnal Aisyah : Jurnal Ilmu Kesehatan Indonesian Journal of Global Health research Journal SAGO Gizi dan Kesehatan Berita Kedokteran Masyarakat Poltekita: Jurnal Ilmu Kesehatan JSSF : Journal of Sport Science and Fitness Jurnal Medika Indonesia
Anjani, Gemala
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Journal : JURNAL GIZI INDONESIA

 1 
Tepung ulat sagu (Rhyinchophorus ferrugineus) imunomodulator Nitric Oxide (NO) sirkulasi mencit terapi antimalaria standar Ariani, Ariani; Anjani, Gemala; Sofro, Muchlis Achsan Udji; Djamiatun, Kis
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 6, No 2 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (447.96 KB) | DOI: 10.14710/jgi.6.2.131-138

Abstract

Background : Sago worm flour (Rhyinchophorus ferrugineus)is a coconut beetle larvae that is processed into flour.This flour contains antioxidants as well as arginine, both of which play a role in modulating oxidative stress including NO involved in immunopathology of cerebral malaria.Objectives : To prove the immunomodulator role of sago worm flour in decreasing circulation  NO level at mice  who received standard antimalarial therapy  Dihydroartemisinin Piperaquine (DHP)Methods : This study was randomized control group post test only design by using 23 Swiss mice which divided into 5 group consist of : K(-) normal mice; K(+) inoculated woth Plasmodium berghei ANKA (PbA); X1 received DHP; X2 received sago worm flour; X3 received both of sago worm flour and DHP. All treatment groups X1,X2 and X3 were inoculated by PbA before treatmen were given. Serum circulation NO level was assessed by ELISA. statistical analysis used was One Way ANOVA followed by Bonferroni post hoc test.Results : The mean  NO level in K(-), K(+), X1, X2, and X3 were 1.008 μmol/mL, K(+) 1.338 μmol/mL; while at treatment X1 1.143 μmol/mL, X2 1.410 μmol/mL, dan X3 0.886 μmol/mL. One way ANOVA showed that they were significantly different (p=0.001). Bonferroni post hoc test of X2 was  proportional to K(+) (p=1.000), whole had NO level lower than either K(+)(p=0.009) or X2 (p=0.002). Conclusion : The immunomodulatory effects of sago worm flour (Rhyinchophorus ferrugineus) reduced circulating NO levels in standard antimalarial therapy recipients.
Effect of Moringa (Moringa oleifera) Leaf Flour Supplementation on Total Antioxidant Content of Sprague Dawley Rat Serum Given High-Fat Diet Sherlin Regina Jami; Siti Fatimah-Muis; Ahmad Syauqy; Kusmiyati Tjahjono; Gemala Anjani
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 10, No 2 (2022): Juni
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.10.2.141-149

Abstract

Background: Moringa oleifera leaf is high in quercetin which can be a source of exogenous antioxidants. Together with endogenous antioxidants, both the antioxidants will be able to counteract oxidative stress conditions.Objectives: To analyze the effect of Moringa leaves flour supplementation on Total Antioxidants Content (TAC) of Sprague Dawley (SD) rat serum given a high-fat diet (HFD). Materials and Methods: A randomized control group post-test design was used on 24 SD rats which were divided into 4 groups, namely healthy control (K1), HFD (K2), supplementation with Moringa leaf flour at a dose of 100 mg/100 g BW/day (K3), and a dose of 200 mg/100 g BW/day (K4). After 28 days of supplementation, serum TAC was analyzed using the ELISA method. Data analysis used Paired-T Test, One Way ANOVA, and Post-Hoc Bonferroni follow-up test.Results: The results showed that the TAC of groups K1, K2, K3, and K4 respectively were 4.806 ± 0.239, 1.323 ± 0.292, 4.020 ± 0.239, and 5.123 ± 0.695. There was a significant difference in serum TAC (p=0.000) between supplementation groups. Significant differences in serum TAC were also found in the supplementation group compared to the HFD control group.Conclusion: Moringa leaves flour supplementation for 28 days at a dose of 200 mg/100 g BW/day increases serum total antioxidant content higher than at a dose of 100 mg/100 g BW/day.
The sociodemographic factors on food insecurity among household living in disaster-prone area in Central Java, Indonesia Hastuti, Vivilia Niken; Afifah, Diana Nur; Sugianto, Denny Nugroho; Anjani, Gemala; Noer, Etika Ratna
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 12, No 2 (2024): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.12.2.136-142

Abstract

Background: Demak, as a disaster-prone coastal area in Central Java, faces issues such as malnutrition and food insecurity due to the impacts of climate change. As a result of coastal disasters, vulnerable people in coastal areas often experience loss of livelihoods, limited access to nutritious food, and increased risk of malnutrition.Objective: The study aimed to analyze the association between household food security and household demographic factors in Central Java’s coastal areas.Materials and Methods: A cross-sectional study was conducted on 138 households living in the coastal area of Demak by simple random sampling. The socio-demographic characteristics were conducted by interviewing the mother/child caregiver. The degree of household food security (HFS) was obtained using the Household Food Security Survey Module (HFSSM) Questionnaire. Descriptive statistics and Chi-square were used for statistical analysis.Results: Based on HFS status, 49.3% of respondents were food secure, 26.1% were food insecure without hunger, 20.3% were food insecure with moderate hunger, and 4.3% were food insecure with severe hunger. There was significant correlation between father’s educational level, mother’s educational level, and monthly household income per month on the HFS status (p<0.05).Conclusion: Sociodemographic factors associated with household food security status were father's and mother's education and monthly household income (p<0.05). The potential negative impact of household food insecurity on the nutritional status of family members needs to be studied further, especially vulnerable age groups such as toddlers and mothers in the household.
Effect of leunca (Solanum nigrum) on inflammatory status in rats induced by high-fat and high-sucrose diet Gunawan, Sekar Ayu Putri; Muis, Siti Fatimah; Anjani, Gemala; Noer, Etika Ratna; Ayustaningwarno, Fitriyono
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 2 (2025): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.2.99-104

Abstract

Background: Consumption of foods that are high in calories over a long period of time is a cause of obesity and can increase proinflammatory cytokines. Leunca fruit contains various phytochemicals that act as anti-inflammatory, antioxidant, and antiobesity but not many people utilize leunca fruit as daily food.Objective: To analyze the effect of leunca fruit on TNF-α and IL-6 levels in rats induced by high fat and sucrose diet (HFSD).Methods: The research design was Randomized Post Test Only Control Group Design. The sample was 30 male Sparague Dawley rats and divided into 5 groups, namely group K1 which was given standard feed, group K2 which was induced by HFSD, group P1 which was induced by HFSD and leunca 0.8g/200gBW, group P2 which was induced by HFSD and leunca 1.6g/200gBW, and group P3 which was induced by HFSD and leunca 2.4g/200gBW. The research was conducted at the Nutrition Laboratory of the Center for Food and Nutrition Studies of Gadjah Mada University (PSPG PAU UGM) Yogyakarta in January-March 2024. Testing TNF-α and IL-6 levels through rat blood serum using the ELISA method. Data were analyzed by ANOVA and Post Hoc test.Results: There was a significant difference in TNF-α and IL-6 levels between experimental groups (p=0.00). The levels of TNF-α and IL-6 in the P1, P2, and P3 groups that received HFSD + leunca were lower than in the K2 group that received HFSD only.Conclusion: Leunca fruit can reduce proinflammatory cytokine levels (TNF-α and IL-6) in HFSD-induced rats.
Liprotide-encapsulated vitamin D3 modulates circulated PTH levels and improved bone microstructure Shauma, Claradhita Ayu; Fulyani, Faizah; Pramono, Adriyan; Mahati, Endang; Putri, Sylvia Rahmi; Maulana, Reza Achmad; Anjani, Gemala
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 12, No 1 (2023): December
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.12.1.44-52

Abstract

Background: vitamin D (25(OH)D) is a fat-soluble vitamin that is unstable in the gastrointestinal environment and has low bioavailability. A protein-lipid complex (liprotide) can be used as a shell to increase vitamin D stability and bioavailability. Liprotide can also serve as a delivery system for transporting vitamin D to its intended site. Little attention has been paid to utilizing liprotide as a delivery system for vitamin D and evaluating its functional activity.Objective: to investigate the effect of liprotide-encapsulated vitamin D3 on PTH levels and bone microstructure in vitamin D and calcium (VD-Ca) deficient rats.Materials and Methods: an overall of 24 Wistar rats had been divided into four groups, a normal control group (K), a VD-Ca group without treatment (K-), a VD-Ca group with 180 IU/200 gBW/day free vitamin D3 (FVD3), and a VD-Ca group with 180 IU/200 gBW/day liprotide-encapsulated vitamin D3 (LVD3). Before and after 28 days of vitamin D intervention, blood samples were taken and analysed for serum PTH levels. The microstructure of the bone was analyzed using the Scanning Electron Microscope (SEM).Results: the VD-Ca rats supplemented with vitamin D3 (FVD3 and LVD3) had a significant decrease in serum PTH levels (p<0.001) and improved bone microstructure (p<0.05) compared to the (K-) group. The reduction of PTH in the LVD3 group was higher compared to the FVD3 group. The bone microstructure between the FVD3 and LVD3 groups is significantly different, as seen in the Ct.Wi parameter, with the LVD3 group having a higher Ct.Wi than the FVD3 group.Conclusion: liprotide-encapsulated vitamin D3 improves the serum PTH level and bone microstructure in a rat model of vitamin D and calcium deficiency.
Co-Authors Abyyudha, Dany Adriyan Pramono Agustina, Ayu Widiawati Ahmad Syauqy Ahmad Syauqy Ahmad Syauqy Ahmad Zulfa Juniarto Al-Baari, Ahmad Ni’matullah Aleda Florince Oyay Amin Husni Anang M Legowo Anggray Duvita W Anggriany, Nissa Ani Margawati Ariani Ariani Ayu Rahadiyanti Ayu, Azzahra Mutiara Ayustaningwarno , Fitriyono Binar Panunggal Bintang, Francisca Natalia Christanto, Monica Lemuela Denny Nugroho Sugianto Deny Yudi Fitranti Dewi Marfu'ah Kurniawati Diana Nur Afifah Diana Nur Afifah, Diana Nur Dwi Ratna Sari Edarni Zebua Edward Kurnia Setiawan Limijadi Edward Kurnia Setiawan Limijadi, Edward Kurnia Setiawan Ekowati Chasanah Endang Mahati Endang Mahati Endang Mahati Endang Sri Lestari Endang Sri Lestari Endang Yuli Purwani, Endang Yuli Enny Probosari Etika Ratna Noer Faizah Fulyani Fatih Az Zahra Fitriyono Ayustaningwarno Fulyani, Faizah Furkaniaty, Annisa Galuh Dwi Astuti Gunawan, Sekar Ayu Putri Hardhono Susanto Hartanti Sandi Wijayanti Hastuti, Vivilia Niken Hunaefi, Dase Indrastati, Nandia Indriyanti, Risa Ivena Claresta Jaeri, Santoso Jalasena, Rizka Akbar Jaswir, Irwandi Juwita, Riza Iska Kis Djamiatun Kusmiyati Tjahjono Kusmiyati Tjahjono Lili Nor Indah Sari Lubis, Syahrani Aulia MADE ASTAWAN Mambaya, Helvi Desi Maria Mexitalia Masruroh, Zulfatul Maulana, Reza Achmad Miftahul Adnan Millah, Shoffyyatul Mira Dian Naufalina Mohammad Sulchan Mohammad Zen Rahfiludin Muchlis Achsan Udji Sofro Muchlis Achsan. Udji Sufro Mumpuni, Ocka Febrian Muniroh, Muflihatul Nafisah Nafisah Nafisah Nani Maharani Nani Maharani Nareswara, Anastu Regita Ninik Rustanti Ninik Rustanti Ninik Rustanti Nur Afifah, Diana Nur Faizah Nurdin, Nurhanifah Muthmainnah Nurhidayati, Lisa Rosyida Nurmasari Widyastuti Nuryanto Nuryanto Pramesti, Yuli Prasetyo, Dwi Yanuar Budi Pristina Adi Rachmawati Putri, Sylvia Rahmi Putut Har Riyadi Rachma Purwanti Rafika, Muhana Rahayu, Gita Riski Rahmawati, Irma Sarita Rahmawati, Siti Irma Randenia, Nabila Ratna Ratna Rena Budiyatri Resti, Nina Retnaningsih Retnaningsih Rimadhani Ulfa Rohmatul Ummah S Fatimah Muis Septiani Septiani Setyawati, Amalia Rani Shauma, Claradhita Ayu Sherlin Regina Jami Siti Fatimah Muis Siti Fatimah Muis Siti Fatimah-Muis Siti Fatimah-Muis Sofro, Muchlis AU Sumardi Widodo Suwito, Maria Rebecca Sylvia Rahmi Putri Tasya Safira Meliasari Teddy Wahyu Nugroho, Teddy Wahyu Tiffany Nisa Arviyani Tri Winarni Agustini Triyanto, Bagaskara Putra Untari Utama, Affini Nurratri Utami, Wahyu Widyasari Velicia, Velicia Welresna Juliatri Putri Rupiasa Widya, Fiona Christina Zhu, Fan