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All Journal International Journal of Public Health Science (IJPHS) Jurnal Gizi dan Pangan JURNAL GIZI INDONESIA Journal of Nutrition College Jurnal Kesehatan Masyarakat Journal of Biomedicine and Translational Research Indonesian Journal of Human Nutrition agriTECH Mutiara Medika: Jurnal Kedokteran dan Kesehatan Jurnal Media Gizi Indonesia (MGI) Warta IHP (Warta Industri Hasil Pertanian) Medical Laboratory Technology Journal GIZI INDONESIA Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Syntax Literate: Jurnal Ilmiah Indonesia Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology AcTion: Aceh Nutrition Journal Jurnal Gizi Klinik Indonesia Jurnal Aplikasi Teknologi Pangan Amerta Nutrition Canrea Journal: Food Technology, Nutritions, and Culinary Journal JURNAL GIZI DAN KESEHATAN Journal of Telenursing (JOTING) Jurnal Aisyah : Jurnal Ilmu Kesehatan Indonesian Journal of Global Health research Journal SAGO Gizi dan Kesehatan Berita Kedokteran Masyarakat Poltekita: Jurnal Ilmu Kesehatan JSSF : Journal of Sport Science and Fitness
Anjani, Gemala
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Poltekita: Jurnal Ilmu Kesehatan

 1 
Effect of Leunca Fruit (Solanum nigrum L.) on Oxidative Stress in rats fed a High Fat High Sucrose Diet Nurdin, Nurhanifah Muthmainnah; Muis, Siti Fatimah; Anjani, Gemala; Noer, Etika Ratna; Ayustaningwarno, Fitriyono
Poltekita: Jurnal Ilmu Kesehatan Vol. 18 No. 3 (2024)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v18i3.3818

Abstract

Decreased levels of superoxide dismutase (SOD) and increased levels of malondialdehyde (MDA) are markers of oxidative stress and indicate obesity. Leunca fruit (Solanum Nigrum L) is a plant that contains antioxidants that can reduce the level of oxidative stress in obesity. The purpose of this study was to determine the effect of leunca fruit administration on SOD and MDA levels in obese rats. This type of research is true experimental with a post-test-only research design where 30 male Sprague Dawley rats were divided into five groups consisting of 2 control groups K(-) and K(+) and three treatment groups (P1, P2, P3). Groups K+, P1, P2, and P3 were fed a high-fat and sucrose diet (21% lard, 34% sucrose). The K (-) control group is a group of healthy rats that only receive standard feed without being given leunca fruit. Group K (+) is a group of obese rats without leunca fruit. Leunca fruit was given for six weeks at a dose of 0.8g (P1), 1.6g (P2), and 2.4g (P3). Serum SOD levels were measured by ELISA method and MDA levels were measured by TBARS method. Statistical analysis using One Way Anova test. Administration of leunca fruit with graded doses can significantly increase SOD activity p=0.000 (p<0.05) and can significantly reduce MDA levels in obese rats in each treatment group p=0.000 (p<0.05). Leunca fruit with a dose of 2.4g/BB rat is the most effective dose to increase SOD levels and reduce MDA levels. The limitation of this study that there is no weighing of the remaining rat feed at each meal, so that the percentage of rat intake is was unknown.
Co-Authors Abyyudha, Dany Adriyan Pramono Agustina, Ayu Widiawati Ahmad Syauqy Ahmad Syauqy Ahmad Syauqy Ahmad Zulfa Juniarto Aleda Florince Oyay Amin Husni Anang M Legowo Anggray Duvita W Anggriany, Nissa Ani Margawati Ariani Ariani Ayu Rahadiyanti Ayu, Azzahra Mutiara Ayustaningwarno , Fitriyono Binar Panunggal Bintang, Francisca Natalia Christanto, Monica Lemuela Denny Nugroho Sugianto Deny Yudi Fitranti Dewi Marfu'ah Kurniawati Diana Nur Afifah Diana Nur Afifah, Diana Nur Dwi Ratna Sari Edward Kurnia Setiawan Limijadi Edward Kurnia Setiawan Limijadi, Edward Kurnia Setiawan Ekowati Chasanah Endang Mahati Endang Mahati Endang Mahati Endang Sri Lestari Endang Sri Lestari Endang Yuli Purwani, Endang Yuli Enny Probosari Etika Ratna Noer Faizah Fulyani Fatih Az Zahra Fitriyono Ayustaningwarno Fulyani, Faizah Furkaniaty, Annisa Galuh Dwi Astuti Gunawan, Sekar Ayu Putri Hardhono Susanto Hartanti Sandi Wijayanti Hastuti, Vivilia Niken Hunaefi, Dase Indrastati, Nandia Indriyanti, Risa Ivena Claresta Jaeri, Santoso Jalasena, Rizka Akbar Juwita, Riza Iska Kis Djamiatun Kusmiyati Tjahjono Kusmiyati Tjahjono Lili Nor Indah Sari Lubis, Syahrani Aulia MADE ASTAWAN Mambaya, Helvi Desi Masruroh, Zulfatul Maulana, Reza Achmad Miftahul Adnan Millah, Shoffyyatul Mira Dian Naufalina Mohammad Sulchan Mohammad Zen Rahfiludin Muchlis Achsan Udji Sofro Muchlis Achsan. Udji Sufro Mumpuni, Ocka Febrian Muniroh, Muflihatul Nafisah Nafisah Nafisah Nani Maharani Nani Maharani Nareswara, Anastu Regita Ninik Rustanti Ninik Rustanti Ninik Rustanti Nur Afifah, Diana Nur Faizah Nurdin, Nurhanifah Muthmainnah Nurhidayati, Lisa Rosyida Nurmasari Widyastuti Nuryanto Nuryanto Pramesti, Yuli Prasetyo, Dwi Yanuar Budi Pristina Adi Rachmawati Putri, Sylvia Rahmi Putut Har Riyadi Rachma Purwanti Rafika, Muhana Rahayu, Gita Riski Rahmawati, Irma Sarita Rahmawati, Siti Irma Randenia, Nabila Ratna Ratna Rena Budiyatri Resti, Nina Retnaningsih Retnaningsih Rimadhani Ulfa Rohmatul Ummah S Fatimah Muis Setyawati, Amalia Rani Shauma, Claradhita Ayu Sherlin Regina Jami Siti Fatimah Muis Siti Fatimah-Muis Siti Fatimah-Muis Sofro, Muchlis AU Sumardi Widodo Suwito, Maria Rebecca Sylvia Rahmi Putri Tasya Safira Meliasari Teddy Wahyu Nugroho, Teddy Wahyu Tiffany Nisa Arviyani Tri Winarni Agustini Triyanto, Bagaskara Putra Untari Utama, Affini Nurratri Utami, Wahyu Widyasari Velicia, Velicia Welresna Juliatri Putri Rupiasa Widya, Fiona Christina Zhu, Fan