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All Journal Jurnal Ilmiah Keperawatan (Scientific Journal of Nursing) Journal of Midwifery and Nursing Abdimas Universal Jurnal Keperawatan dan Kesehatan Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal EduHealth Jurnal Indragiri Penelitian Multidisiplin Unram Journal of Community Service (UJCS) Journal of Applied Nursing and Health Jurnal Keperawatan 'Aisyiyah JIPM: Jurnal Indragiri Penelitian Multidisiplin TRIMAS: Jurnal Inovasi dan Pengabdian Kepada Masyarakat IKHLAS: Jurnal Pengabdian Dosen dan Mahasiswa Jurnal Pengabdian Masyarakat Bangsa Sahabat Sosial: Jurnal Pengabdian Masyarakat Barongko : Jurnal Ilmu Kesehatan Jurnal Kajian dan Penelitian Umum International Journal of Health Sciences Nursing Applied Journal Jurnal Pengabdian Masyarakat dan Riset Pendidikan Jurnal Lentera Kesehatan Masyarakat (JLKM) Buletin Pos dan Telekomunikasi Smart Dedication: Jurnal Pengabdian Masyarakat Jurnal Siti Rufaidah Jurnal Riset Keperawatan dan Kesehatan Research Psychologie, Orientation et Conseil
Sri Ariyanti
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Effect of Henderson’s Need Theory–Based Nursing Care on Medication Adherence among Patients with Tuberculosis: A Quasi-Experimental Study Wahyuni, Tri; Jiu, Cau Kim; Ariyanti, Sri
Journal of Applied Nursing and Health Vol. 8 No. 1 (2026): Journal of Applied Nursing and Health
Publisher : Chakra Brahmanda Lentera Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55018/janh.v8i1.525

Abstract

Background: Medication adherence remains a major challenge in tuberculosis (TB) management, particularly in low- and middle-income countries where socioeconomic and health system barriers affect treatment continuity. Although educational and psychosocial interventions have shown benefits, the application of structured nursing theories in TB care is still limited. This study aimed to examine the effect of Henderson-based nursing care on medication adherence among TB patients Methods: This quasi-experimental study with a pretest–posttest control group design followed the TREND reporting guideline. A purposive sampling procedure was conducted by screening outpatient TB registries and applying predefined inclusion and exclusion criteria, resulting in 60 eligible participants (intervention n = 30; control n = 30). The independent variable was nursing care based on Henderson’s fourteen fundamental needs, while the dependent variable was medication adherence. Adherence was measured using a validated Medication Adherence Scale (Cronbach’s α = 0.87). Before parametric testing, assumptions of normality and homogeneity of variance were examined. Paired and independent t-tests were performed, and ANCOVA was used to control for age, education level, and treatment duration. Effect size (Cohen’s d) and 95% confidence intervals (CI) were calculated. Results: Baseline characteristics were comparable between groups (p > 0.05). In the intervention group, mean adherence scores increased from 68.7 ± 8.9 to 88.3 ± 6.4 (mean difference = 19.6; 95% CI: 16.1–23.1; p < 0.001), representing a large effect size (Cohen’s d = 2.52). The control group showed no significant improvement (mean difference = 2.4; p = 0.27). The adjusted mean difference between groups at posttest was 16.8 points (p < 0.001). Additionally, the proportion of patients classified as having high adherence increased substantially in the intervention group compared to the control group. ANCOVA confirmed a significant intervention effect (F = 64.82; p < 0.001), independent of demographic covariates. Conclusion: Henderson’s Need Theory–based nursing care significantly improves medication adherence among TB patients and demonstrates a large clinical effect. Integrating structured, theory-driven nursing interventions into routine TB services may strengthen adherence-focused care, enhance patient independence, and contribute to improved treatment completion rates in resource-limited settings.
Co-Authors Abdullah Abdullah Airin Putri Aprilia Aisyah Sapitri Almumtahanah, Almumtahanah Amelyadi, Amelyadi Aminuyati Anggeraeni, Anggeraeni Annisa Rahmawati Arfah, Andi Armatella Makdalena Arnes Yuli Vandika Aryadi, Anggi Auliya Apriyanti Awaliah, Nur Rahmah Awangga Febian Surya Admaja Ayu Diana Meilantika Ayu Romantika B. Tamas Arbania Efendi Bhakti, Wida Kuswida Budi Agus Purwanto cahyono, didik Caswita Caswita Cau Kim Jiu Devi Novianti, Devi Diah Yuniarti Djaswadi Dasuki Doan Perdana Dwi Ariani, Desti Dwi Nurfajriyah Dwi Rahayu, Indah Elsyana Fadhilah Elva Nur Setyani Erin Sastrini, Yovita Erlando, Zeri Fahreza, Hafidz Irman Farhan Pramudia Febriyanti, Adinda Gita Fitriani Gusti Nadhif Khalil Farras Halmar, Halbina Famung Hapis, Hapis Hidayah hidayah Hidayah, Hidayah Hoda, Ferdinandus Suban Indri Erwhani Irwan Hadi Islaeli, Islaeli Januardi Jie, Lie Jixiong, Cai Juniarsi, Tya K, Hairuddin Kaharuddin, Riski Muhammad Akbar Kalista Islami Putri Kardiatun, Tutur Kawuryan, Uji Khairillah, Yuyun Nisaul Kuswida Bhakti, Wida Lestari Makmuriana Lidia Hastuti Lucky Amanda Luhur Pidekso Arif Lukita, Yenni M. Agus Jabir M. Coesamin Mardiyani, Ridha Masdarwati, Masdarwati Minduri, Cinta Mirna Husnanida Mora, Mora Muhammad Abizar Al Gifari Muhammad Yusron Maulana El-Yunusi Mulat, Trimaya Cahya Nabila Nabila Natila Chantika Soedirman Ningsih, Warti Nur Siti Aisyah Nursinah, A. Pannyiwi, Rahmat Pella, Yosin Herloheti Pertiwi, Gracia Herni Pramudia, Farhan Putri, Kalista Islami Putri, Nur Ahlam Nadia R Siti Rukayah RACHMAT RAMLI Radiah Ilham Rahmat Rahmat Randika, Rendi Rasyid, Djusmadi Rikayati Rina, Maria Feri Rizki Andita Noviar Rosida Rosida Safira, Annisa Safrina Ramadhani Santoso Sapnita, Sapnita Sima, Yenny Sipahutar, Pongky Siti Masdah SITI SAODAH Sufiana Sukartina Surtikanti SURTIKANTI SURTIKANTI Surtikanti Surtikanti Sutikanti SUTRISNO Sutrisno, Sutrisno Syifa Putri Ramadhanti Tri Wahyuni tri wahyuni Tutur Kardiatun Tyara Bella Safira Usman Usman Wahyuni, Ria Wien Fitrian R. Wuriani, Wuriani Yogi Alfianto Yulis, Dian Meiliani Yuniar Fadila Yunita Kristina