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Agrijanti, Agrijanti
Poltekkes Kemenkes Mataram, Mataram, Nusa Tenggara Barat
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Effect of Patients Taking Amlodipine on Urea Levels Nurhidayati, Nurhidayati; Inayati, Nurul; Agrijanti, Agrijanti
Eduvest - Journal of Universal Studies Vol. 4 No. 7 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i7.1613

Abstract

Background: Hypertension is a condition when blood pressure increases or is often referred to as a “silent killer” because signs and sympotoms occur, usually causing headaches, nosebleeds, irreguler heartbead, fan buzzing in the ears, hypertension is a disease that is often found among elderly. Research Purposes: To determine the effect of patients taking amlodipine on urea levels. Research Methodos: Analytic observational research with cross sectional research design. Used 24 sampels of hypertension who consumend the drug amlodipine and analyzed the data using a non parametric test. Result: The mean results of examining urea levels in patients taking amlodipine were 31,61. Conclusion: There wa a significant effect of patients taking the drug amlodipine on urea levels according to adherence in taking the a p value of 0,003 (p<0,05). The results of blood pressure meansurements of patients taking the drug averaged 145 mg/dl.
PENGGUNAAN SONGGAK SUKU SASAK UNTUK MENURUNKAN KADAR GULA DARAH PENDERITA DIABETES MELLITUS DI KELURAHAN DASAN CERMEN, KOTA MATARAM Kusuma Dewi, Lale Budi; Khusuma, Ari; Agrijanti, Agrijanti; Wulandari, Ayu Nurislami
Jurnal Pengabdian Masyarakat Sasambo Vol. 5 No. 2 (2024): Mei
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jpms.v5i2.1502

Abstract

Data dari profil Puskesmas Babakan, tingkat obesitas penduduk, dari 3.824 yang diperiksa, ditemukan 1.053 orang (27%) diantaranya dinyatakan obesitas. Sebanyak 90-95% kasus diabetes adalah DM tipe 2, yang sebagian besar dapat dicegah karena disebabkan oleh gaya hidup yang tidak sehat.  Tujuan pengabdian ini sebagai upaya membantu mengendalikan kadar gula darah penderita hiperglikemia dengan ramuan tradisional suku sasak, Songgak. Sebanyak 45 masyarakat yang hadir dalam kegiatan sosialisasi diperiksa kadar gukosa darahnya, sebanyak 14 orang memiliki kadar gula darah sewaktu ≥200mg/dl. Songgak disosialisasikan dan disampaikan hasil penelitian tentang manfaat songgak untuk menurunkan kadar glukosa darah. Setelah konsumsi songgak selama dua  minggu, terjadi penurunan kadar glukosa darah sewaktu pada 21 peserta. Masyarakat paham pentingnya menjaga pola hidup dan pentingnya pemeriksaan glukosa darah secara berkala bagi penderita DM. Data profile of the Babakan Health Center, the obesity level of the population, of the 3,824 examined, 1,053 people (27%) were found to be obese. As many as 90-95% of diabetes cases are type 2 DM, most of which can be prevented because they are caused by an unhealthy lifestyle. The purpose of this service is as an effort to help control blood sugar levels of hyperglycemia sufferers with the traditional ingredients of the Sasak tribe, Songgak. As many as 45 people who attended the socialization activity had their blood glucose levels checked, as many as 14 people had blood sugar levels when ≥200mg/dl. Songgak was socialized and presented the results of research on the benefits of Songgak for lowering blood glucose levels. After consuming Songgak for two weeks, there was a temporary decrease in blood glucose levels in 21 participants. The community understands the importance of maintaining a lifestyle and the importance of regular blood glucose checks for people with DM.
The Effect of Roasting Methods of Ingredients The Songgak Tribe Sasak Herbal on Active Compounds Using Gas Chromatography Mas Spectroscopy (Gc-Ms) Analysis) Agrijanti, Agrijanti; Kusuma Dewi, Lale Budi; Khusuma, Ari; Wardoyo, Eustachius Hagni
Jurnal Kesehatan Prima Vol. 18 No. 2 (2024): AUGUST
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkp.v18i2.1540

Abstract

Songgak is a concoction of the Sasak tribe of Lombok in West Nusa Tenggara. It consists of coffee mixed with groundwood, cloves, black pepper, coriander, and nutmeg. The original recipe involves roasting the spices before mixing them with coffee, namely using a frying pan over a stove. The roasting process is carried out without controlling the temperature and roasting time, so the roasted ingredients need to be standardized(Dewi et  al., 2021). GCMS is a tool used to analyze compounds in samples using chemical separation methods, mainly chromatography. The compounds in the mixture are separated in a chromatographic column. The separation mechanism between several compounds occurs due to differences in the solubility values of each in the moving solvent and differences in the absorption of each of the competing compounds into the stationary phase (Gross, 2017). In this research, variations will be carried out on spices, namely T1 original treatment of roasting spices over fire for 8 minutes, T2 drying spices in sunlight, T3 oven for 5 minutes, T5 oven for 5 minutes, T4 oven for 15 minutes and T5 oven for 15 minutes. In the T4 treatment, namely oven for 10 minutes, the results of the analysis of the substance content with the most types, namely 20 types, were obtained. The active anti-microbial compound found in all treatments was Hexadecanoic acid, 2-hydroxy-1-(h)(C19 H38 O4) BM:330, which helps inhibit the growth of cancer cells. (National Library Medicine, n.d.). Octadecanoic acid (CAS) Stear (C18 H34 O2) BM:282 Anti-inflammatory, Antiandrogenic Cancer prevention, Hypocholesterolemia Dermatigenic, 5-Alpha reductase inhibitor, Anemiagenic, Insecticide (Natarajan et al., 2019) and Tetradecanoic acid (CAS) Myris (C14 H28 O2) BM:228 as anti-inflammatory and anti-nociceptive. 
Odds Ratio of Increase in Hemoglobin Level Associated with Consumption of Songgak Coffee in Patients with Pulmonary TB Dewi, Lale Budi Kusuma; Hartuti, Sri; Getas, I Wayan; Agrijanti, Agrijanti; Tatontos, Erlin Yustin; Wiadnya, Ida Bagus Rai; Zaetun, Siti; Khusuma, Ari
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Pulmonary TB cases in Indonesia are the second highest in the world. The incidence of Anemia in pulmonary TB patients can be as high as 90%. Anemia can lead to poor outcomes in the recovery of pulmonary TB. Songgak coffee is a coffee with a mixture of spices that is commonly consumed by the people of Central Lombok to make the body healthy and increase vitality, including pulmonary TB patients. Songgak coffee is made from 7 types of spices mixed with coffee. The results of previous research show that Songgak coffee has quite good antioxidant content and is an immunostimulant. Antioxidants may increase Hemoglobin levels. This was a case-control study. A total of 26 new pulmonary TB patients were divided into 2 groups. Group A received songgak coffee as an additional anti-TB drug, while group B received anti-TB drug therapy alone. Hemoglobin levels in groups A and B were measured before drug administration and 14 days after treatment. The data collected were nominal data, reported as increasing and non-increasing. A total of 12 out of 13 patients in group A had an increase in Hemoglobin, while only 1 person in group B had an increase in Hemoglobin. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who consume songgak is 12. The odds ratio value for increasing Hemoglobin in pulmonary TB patients taking songgak is 12. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who take Songgak is 12 times higher than in pulmonary TB patients who do not take Songgak.
Optimalisasi Tepung Talas Mbote (Xanthosoma Sagittifolium) Sebagai Media Alternatif Pertumbuhan Jamur Aspergillus Sp dan Candida Albicans azwa rafiza; Rohmi; Erna Kristinawati; Agrijanti
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 2 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i2.224

Abstract

Latar Belakang: Jamur patogen seperti Aspergillus sp. dan Candida albicans menyebabkan infeksi seperti aspergillosis dan kandidiasis, terutama pada individu imunokompromais. Media kultur standar PDA mahal, sehingga diperlukan alternatif lokal seperti tepung talas mbote yang kaya karbohidrat (41%), protein (15%), lemak (1,4%), mineral, dan vitamin. Talas mbote berpotensi sebagai substrat nutrisi untuk pertumbuhan jamur karena kandungan gizinya yang mendukung metabolisme karbon. Tujuan Penelitian: Penelitian bertujuan mengoptimalkan berbagai formula tepung talas mbote (4 gr, 3,5 gr, 3 gr, 2 gr, 1 gr) sebagai media alternatif pertumbuhan Aspergillus sp. dan Candida albicans dibandingkan PDA. Analisis dilakukan untuk membandingkan diameter koloni Aspergillus sp. dan jumlah koloni Candida albicans pada media tersebut. Metode Penelitian: Penelitian pre-eksperimental dilakukan di Laboratorium Mikrobiologi TLM Poltekkes Kemenkes Mataram pada Desember 2024-Januari 2025 dengan 4 perlakuan formula tepung talas mbote. Inokulasi jamur diinkubasi 3x24 jam pada suhu optimal, dianalisis secara deskriptif melalui pengukuran diameter koloni Aspergillus sp. dan hitung koloni Candida albicans. Hasil Penelitian: Pada Aspergillus sp., formula 4 gr menghasilkan diameter koloni terbesar 23 mm (rata-rata 51,5 mm), melebihi PDA (rata-rata 49 mm); formula 3,5 gr 22 mm. Pada Candida albicans, formula 4 gr tumbuh 25 koloni (rata-rata 55,5), lebih tinggi dari PDA (rata-rata 42); formula 3,5 gr 24 koloni. Semua formula menunjukkan pertumbuhan optimal, didukung enzim amilase yang menguraikan karbohidrat menjadi glukosa. Kesimpulan: Tepung talas mbote Xanthosoma sagittifolium efektif sebagai media alternatif optimal untuk pertumbuhan Aspergillus sp. dan Candida albicans, terutama formula 4 gr dan 3,5 gr yang sebanding atau melebihi PDA. Media ini ekonomis dan nutrisi lengkap, cocok untuk laboratorium dengan keterbatasan sumber daya.
Pengaruh Jenis Pengobatan terhadap Kadar Gula Darah 2 Jam Post Prandial pada Pasien Diabetes Melitus Tipe-2 Jasmine Chairunnisa; Agrijanti; Ari Khusuma; Pancawati Ariami
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 2 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

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Abstract

ABSTRACT Latar Belakang: Diabetes Melitus Tipe 2 disebabkan oleh gangguan sekresi atau fungsi insulin yang menyebabkan akumulasi glukosa dalam darah, sehingga merusak organ seperti jantung, pembuluh darah, mata, ginjal, dan saraf. Prevalensi diabetes di Indonesia meningkat signifikan, dengan 19,5 juta penderita pada 2021 menurut IDF, termasuk 64.544 kasus di Nusa Tenggara Barat pada 2023. Pengukuran gula darah 2 jam post prandial penting untuk menilai efektivitas pengobatan dalam mengontrol glukosa pasca makan. Tujuan Penelitian: Penelitian bertujuan mengetahui pengaruh pengobatan metformin, glibenklamid, dan kombinasi metformin-glibenklamid terhadap kadar gula darah 2 jam post prandial pada pasien Diabetes Melitus Tipe 2. Selain itu, menganalisis mekanisme kerja obatobatan tersebut dalam menurunkan glukosa darah untuk meningkatkan pengendalian glikemik. Metode Penelitian: Penelitian analitik observasional potong lintang menggunakan data sekunder dari 96 rekam medis pasien DM Tipe 2 di RSUD Patut Patuh Patju periode JanuariDesember 2024, dengan sampel purposive (32 metformin, 32 glibenklamid, 32 kombinasi). Analisis dilakukan dengan uji nonparametrik Kruskal-Wallis setelah uji normalitas KolmogorovSmirnov. Hasil Penelitian: Rerata gula darah puasa dan 2 jam post prandial sebelum pengobatan: metformin (157 dan 151 mg/dL), glibenklamid (154 dan 150 mg/dL), kombinasi (189 dan 162 mg/dL), menunjukkan penurunan kadar gula darah pada ketiga kelompok. Uji Kruskal-Wallis menghasilkan p=0,081 (puasa) dan p=0,886 (2 jam post prandial), tidak ada perbedaan signifikan antar pengobatan (p>0,05). Kombinasi metformin-glibenklamid memberikan penurunan rerata terbaik (selisih 27 mg/dL). Kesimpulan: Ketiga jenis pengobatan menurunkan kadar gula darah 2 jam post prandial pada pasien DM Tipe 2, dengan kombinasi metformin-glibenklamid paling optimal meskipun tidak signifikan secara statistik. Pengendalian glikemik lebih baik pada terapi kombinasi, dipengaruhi faktor seperti pola makan dan kepatuhan pasien.
Co-Authors Aeni Halawiya Alfiah Novianty Anisa Prisilia Prisilia Ari Khusuma azwa rafiza Baiq Lilis Septiana Cahayaningrum, Aryani Dewi, Lale Budi Kusuma Dwi Melbaow Aisyiah Putri Erlin Yustin Tatontos Erna Kristinawati Erna Kristinawati Eustachius Hagni Wardoyo Fadhilah Rizkiyah Febriza Marta Utami Fihiruddin, Fihiruddin Getas, I Wayan I Made Wahyu Waisnawa I Wayan Getas I Wayan Getas Imanta Alifia Octavira Intan Suryawatie Yomo, Meidiana Jasmine Chairunnisa Lalu Srigede Lalu Srigede Lalu Srigede, Lalu Lina Sundayani Meidiana Intan Suryawatie Yomo Muhammad Luthfi Ni Komang Ari Santi Widyastini Nispahayati Nispahayati Nova Ramdhani, Iid Nirmala Novianty, Alfiah Nurhidayati Nurhidayati Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Octavira, Imanta Alifia Pancawati Ariami Permatasari, Lina Putriawati Putriawati Putriawati, Putriawati RAI WIADNYA, IDA BAGUS Rohmi Rohmi Rohmi Rohmi Rohmi Rohmi Rohmi Rohmi, Rohmi Siti Karyani Siti Zaetun Siti Zaetun Siti Zaetun Siti Zaetun, Siti Sri Hartuti Sudirman Halla Sufina Zikria Putri Supriyanti, Ispi Thomas Tandi Manu Vivi Oktapia Wahyuni, Leni Waisnawa, I Made Wahyu Widyastini, Ni Komang Ari Santi Wulandari, Ayu Nurislami Yudha Anggit Jiwantoro Yuliana Tri Risky Yunan Jiwintarum Zahira, Jauhara Rana