Article Per Year (5 Year)
p-Index From 2021 - 2026
5.454
P-Index
This Author published in this journals
All Journal BIOTROPIA - The Southeast Asian Journal of Tropical Biology Prosiding Seminas Competitive Advantage Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Prosiding Seminar Nasional Sains Dan Teknologi Fakultas Teknik Indonesian Journal of Mathematics and Natural Sciences Biota Jurnal Pendidikan Biologi Indonesia Biology, Medicine, & Natural Product Chemistry Bioeksperimen: Jurnal Penelitian Biologi Jurnal Penelitian LPPM (Lembaga Penelitian dan Pengabdian kepada Masyarakat) IKIP PGRI MADIUN Jurnal Florea Biodidaktika : Jurnal Biologi dan Pembelajarannya DIDAKTIKA BIOLOGI: Jurnal Penelitian Pendidikan Biologi Jurnal Pendidikan Biologi Jurnal SOLMA Journal of Islamic Medicine Jurnal Biolokus: Jurnal Penelitian Pendidikan Biologi dan Biologi Premiere Educandum: Jurnal Pendidikan Dasar dan Pembelajaran Bio-Lectura International Journal of Community Service Learning International Conference on Mathematics and Science Education of Universitas Pendidikan Indonesia JPM PAMBUDI Dedication : Jurnal Pengabdian Masyarakat DIDAKTIKA : Jurnal Kependidikan BIO-EDU: Jurnal Pendidikan Biologi Community Development Journal: Jurnal Pengabdian Masyarakat Sains dan Matematika Belantika Pendidikan Jurnal Pengabdian UNDIKMA Bioscientist : Jurnal Ilmiah Biologi Jurnal Pengabdian kepada Masyarakat Berkala Penelitian Hayati Life Science Pharmademica: Jurnal Kefarmasian dan Gizi Plyometric : Jurnal Sains dan Pendidikan Keolahragaan Literasi: Jurnal Pengabdian Masyarakat dan Inovasi Dedication : Jurnal Pengabdian Masyarakat JPM Pambudi Edubiotik : Jurnal Pendidikan, Biologi dan Terapan Proceeding of International Conference on Biology Education, Natural Science, and Technology Biodiversitas Journal of Biological Diversity
Cicilia Novi Primiani
Universitas PGRI Madiun
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

Published : 61 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 61 Documents
Search

 3   4   5   6   7 
Penggunaan Polivinil Pirolidon (PVP) sebagai Bahan Pengikat pada Formula Granul: Literatur Review Safitri, Rusiana Yulia; Bhagawan, Weka Sidha; Primiani, Cicilia Novi Primiani
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 4 No 1 (2024): April - September
Publisher : LPPM-KI - POLTEKKES PIM (Formerly AKAFARMA-AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54445/pharmademica.v4i1.56

Abstract

Granule preparations are lumps of small particles that are uneven in shape and become single, larger particles. The process of making granule preparations uses a technique, namely granulation. In the granulation process, a binder is needed to unite the powder particles into a granule preparation. The binder material that is often used is polyvinyl pyrrolidone (PVP). The use of PVP is able to produce an optimal granule preparation that meets the requirements. This research reviews the use of PVP as a binding agent in making granule preparations. This research method uses a literature study method in the form of primary references in the form of national journals from the last 10 years searched in the Google Scholar, PubMed, and ScienceDirect databases. Search for this data source using the keywords Use of PVP as a binding agent in granule preparations. The results and conclusions of the research show that the use of PVP as a binding agent in granular preparations can produce preparations that meet the requirements.
The effect of genitri (Elaeocarpus ganitrus) in leukocytes profile of wistar rats as a prospective immunomodulatory agent Primiani, Cicilia Novi; Pujiati, Pujiati; Bhagawan, Weka Sidha; Waris, Waris; Krisnamurti, Gabriella Chandrakirana
Jurnal Biolokus : Jurnal Penelitian Pendidikan Biologi dan Biologi Vol 8, No 1 (2025): June
Publisher : Universitas Islam Negeri Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30821/biolokus.v8i1.3987

Abstract

Immunomodulator is an agent to activate and modulate the immune response. It is one of the approaches to prevent chronic disease and maintain homeostasis. Recently,  plant phytochemicals have been developed as prospective immunomodulatory agents. Genitri (Elaeocarpus ganitrus), a local plant cultivated in Indonesia, exhibited various biological properties and potential as an immunomodulatory agent. This study aims to identify the potency of genitri as immunomodulatory agent through leukocyte profiling. Genitri leaf (P1), seed (P2), and fruit (P3) were prepared as powder and administered to male wistar rats weighted 250-300 g twith six replications for 28 days. The total leukocytes were  counted and leukocytes were being  profiled following the treatment with genitri powder then  compared with control treatment (P0). The immunomodulatory activity of genitri was shown by the increased leukocytes count following treatment. Based on data from the treatment group (P2), genitri seeds were able to increase leukocytes by 10595.83 cells/µl. The highest total leukocytes were found in treatment P2 with total leukocytes 10595.83 cells/µl. Based on the leukocyte profile, lymphocytes and monocytes were found to be the highest in all treatments. Treatment with genitri was able to stimulate an increase in lymphocytes and monocytes. An increase in total leukocytes given genitri is an indication of an increased immune response.
Profile of flavonoid bioactive compounds in moringa leaves (Moringa oleifera) as phytoestrogens Primiani, Cicilia Novi; Pujiati , Pujiati; Prayitno, Trio Ageng; Setiawan, Mohammad Arfi; Rivera, Alice Tonido
Edubiotik : Jurnal Pendidikan, Biologi dan Terapan Vol. 10 No. 01 (2025): Edubiotik : Jurnal Pendidikan, Biologi dan Terapan
Publisher : Biology Education Department, Universitas Insan Budi Utomo, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33503/ebio.v10i01.1446

Abstract

Moringa oleifera with the local name moringa, is widely used for health, as a medicinal plant. However, its potential as a natural estrogenic is not yet known. The study aimed to analyse and identify flavonoid compounds of moringa leaves and to analyse the estrogenic potential of moringa leaves on 17β-estradiol levels of female rats. Research with an experimental approach includes: 1) Metabolite profiling of moringa leaf extract using 95% methanol solvent, with stages including extract dilution, protein precipitation, and extract purification with SPE. Extract purification using solid phase extraction using C18 Sep-Pak; 2) Induction to 4-5 months female Wistar rats, 240 - 280 g, 24 heads, grouped into 3 treatment groups, namely control (P0), administration of 17β-estradiol (P1) and administration of 1.5 ml moringa leaf feeling water (P2), treatment for 25 days. Data collection techniques include LCMS chromatogram data and data on 17β-estradiol levels taken from rat tail veins. Descriptive data analysis techniques include: 1) Chromatogram result data of flavonoid compound groups and 2) Data on 17β-estradiol levels using ELIZA on day 26. The conclusion of the results showed that the flavonoid compounds of moringa leaves were 29 compounds, including isoflavone and coumestan groups. Giving moringa leaf juice can increase 17β-estradiol levels in rats by 524.346 mg/dl.
Peningkatan Mutu Produk Jamu Home Industry pada Kelompok Jamu Gendong Desa Karangrejo Kabupaten Magetan di Masa Pandemi Covid-19 Cicilia Novi Primiani; Pujiati Pujiati; Mohammad Arfi Setiawan
Jurnal Pengabdian UNDIKMA Vol. 2 No. 2 (2021): November
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v2i2.4128

Abstract

The purpose of this community service activity is to improve the quality of jamu gendong products at the home industry of jamu gendong in Karangrejo village, Magetan Regency. The method of service is carried out by training, including procedures for pre-survey activities, surveys, socialization, training, and evaluation. The target of the service activity is the women of the jamu gendong group. The evaluation results showed an increase in participant understanding of 56% about the technique of selecting rhizomes for herbal medicine, an increase in participant understanding of 44% about equipment selection techniques for herbal medicine, an increase in participant understanding of 72% about the hygienic process of making herbal medicine, an increase in participant understanding of 66% about the hygienic packaging process of herbal medicine. The results of monitoring and evaluation showed that 100% of participants were satisfied in participating in the activities, 100% of participants took an active role in participating in the training, 100% of participants were enthusiastic in participating in the activities.
Pemberdayaan Kelompok PKK Melalui Pelatihan Pembuatan Batik Jumputan Pewarna Alam sebagai Ciri Khas Desa Mojorejo Kabupaten Madiun Cicilia Novi Primiani; Rafaella Chandraseta Megananda; Pujiati Pujiati
Jurnal Pengabdian UNDIKMA Vol. 3 No. 3 (2022): November
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v3i3.5538

Abstract

The purpose of this community service is to empower the Family Welfare Empowerment (PKK) group by developing the creativity of natural dye batik products in order that they can become the typical batik of Mojorejo Village, Madiun Regency. The method of implementing the service activity is through the stages: 1) observation, 2) counseling, 3) training, and 4) evaluation. The target of service activity is the PKK group. The data collection technique used a questionnaire and an observation rubric. Descriptive data analysis is based on achievement indicators. Based on the questionnaire analysis, it was found that the creativity of the trainees increased by 40%. The motivation of the trainees increased by 70%. The understanding of the training participants about the process of making natural dyed batik increased by 90%. The conclusion of the service activity is that training on making Jumputan batik using natural dyes can increase the creativity of batik production, which is typical of Mojorejo Village, Madiun Regency.
Edukasi Gizi Seimbang dan Penyakit Degeneratif bagi Lansia Desa Kenongrejo Kabupaten Madiun Lukas Susanto; Andri Wahyu Utomo; Puri Ratna Kartini; Roy Putra; Desi Kusumawati; Mohammad Arfi Setiawan; Cicilia Novi Primiani
Jurnal Pengabdian UNDIKMA Vol. 4 No. 3 (2023): August
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v4i3.8343

Abstract

This service aims to increase the knowledge of the elderly in Kenongrejo Village regarding balanced nutrition and degenerative diseases. The method of implementing this service was socialization and mentoring. The evaluation instrument for this activity was the help of an evaluation rubric which was then analyzed descriptively. The results of this service showed that the knowledge of the elderly regarding food menu arrangements for the elderly increased by 45%; participants' understanding of various degenerative diseases that occurred in the elderly increased by 30%; awareness of the importance of routine health control for the elderly increased by 42%; participants' motivation in participating in outreach/counseling increased 30%; and implementation of socialization/counseling programs increased 100%. Based on the service activities that had been carried out, socialization and mentoring activities were going well and could provide changes in behavior patterns for the elderly in Kenongrejo Village.
Analysis of Misconceptions on Reproductive System Material in Class XI IPS 2 Students of SMA Negeri 6 Madiun Rahmawati, Jevi Milda; Nurcahyo, Ima Agung; Primiani, Cicilia Novi
Proceeding of International Conference on Biology Education, Natural Science, and Technology 2023: Proceeding of International Conference on Biology Education, Natural Science, and Technology
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Conceptual understanding forms the basis of an important component in mastering higher-order thinking skills. This ideal condition is not in accordance with the fact that there are still many students who experience misconceptions. This study aims to determine the level of misconceptions that occur in students of class XI IPS 2 SMA Negeri 6 Madiun. The research method used in this study is descriptive-quantitative with survey techniques. The sample used was 34 students. The results of this study were that 64.7% of students did not understand the process of birth or gestation, 61.8% did not understand the stages of embryo development, 58.8% did not understand the stages of the ovarian cycle, 67.6% experienced misconceptions about the types of material contraception, 52.9% had misconceptions about reproductive system disorders sub-material, 48.5% had misconceptions about oogenesis stages sub-material, 41.2% understood reproductive system disorders sub-material, 38.2% understood spermatogenesis stages sub-material (38.2%), and 38.2% understood the benefits of breastfeeding for mothers and babies.
Manuscript Writing Guidelines: Analysis of Creative thinking skills profile of Senior High school students in Madiun City on Biotechnology topic Nurdiana, Herning; Nurcahyo, Ima Agung; Primiani, Cicilia Novi
Proceeding of International Conference on Biology Education, Natural Science, and Technology 2023: Proceeding of International Conference on Biology Education, Natural Science, and Technology
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Currently, the world of education has returned to normal after the outbreak of Covid-19. The newest curriculum implemented in Indonesia is the independent curriculum. One of the important competencies trained in the independence curriculum is creative thinking skills. Creative thinking skills are important for long-term success because they help see problems and situations from different perspectives to solve problems. The purpose of this study was to analyze the profile of students' creative thinking skills in biotechnology material. This research is a descriptive research with a written test method that includes creative thinking skills. The subjects of this study were 35 students of SMAN 6 Madiun who were selected using a purposive sampling technique. The results obtained show that the percentage of achievement of creative thinking skills as measured using 4 aspects of adaptive creative thinking skills according to Torrance and Guildford namely fluency 60%, flexibility 44,64%, originality 40,36%, and elaboration 57,85%.
Development of Circulation System E-Dioclass to Foster Critical Reasoning and Cognitive Learning Outcomes Farida Nuraini; Mimien Henie Irawati Al-Muhdhar; Zainudin Hassan; Murni Sapta Sari; Deny Setiawan; Cicilia Novi Primiani; Wachidatul Linda Yuhanna; Feni Tin Faizah
DIDAKTIKA Vol 20 No 01 (2026): DIDAKTIKA : JURNAL KEPENDIDIKAN
Publisher : Fakultas Tarbiyah Institut Agama Islam Negeri (IAIN) Bone

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30863/didaktika.v20i01.9979

Abstract

Critical reasoning skills are still relatively low among students and have a significant impact on cognitive learning outcomes. This study aims to produce E-Dioclass learning media on the PBLPOE model of circulatory system material integrated with SDGs number 3 to develop critical reasoning dimensions and cognitive learning outcomes of phase F students that are valid and practical. The research model used is the Lee & Owens development model with five stages, namely analysis, design, development, implementation, and evaluation. The analysis stage aims to identify the needs of teachers and students. The design stage aims to design E-Dioclass media. The development stage is to realize the design in the form of a storyboard to become a prototype. The implementation stage is to apply the media in four meetings. The evaluation stage is to determine the effectiveness of the media. E-Dioclass media is a Google Classroom-assisted media that can be accessed online through electronic devices. The results of E-Dioclass media validation by media experts, material experts, and biology education practitioners obtained an average score of 95.7%. The results of the practicality test obtained a score of 81.6%. Therefore, E-Dioclass media is declared valid, practical.
IN SILICO STUDY OF JATI (Tectona grandis) LEAF CONSTITUENTS AS TRADITIONAL WOUND CARE Gabriella Chandrakirana Krisnamurti; Anak Agung Sagung Alit Sukmaningsih; Cicilia Novi Primiani
BIOTROPIA Vol. 32 No. 3 (2025): BIOTROPIA Vol. 32 No. 3 December 2025
Publisher : SEAMEO BIOTROP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11598/btb.2025.32.3.2456

Abstract

HIGHLIGHTS- T. grandis leaf methanolic extract contains 82 compounds, with 17 being predominant.- Epigallocatechin 3-O cinnamate, epigallocatechin 3-O-p-coumarate, and tectograndinol predicted as the potential bioactive compounds in wound healing- Molecular docking suggests inhibitory activities against NF-κB, MMP-2, and MMP-9, and stimulatory activity against EGFR-1 that comparable to commercial drugs. ABSTRACTWound-healing process involves a physiological cascade to restore skin integrity, which includes inflammatory response, cell proliferation, and tissue reconstruction. Prolonged inflammation in wound-healing process may lead to a chronic wound stage. Proper wound care is needed to prevent wound-caused mortality. Several studies showed the potential of T. grandis leaf in wound-healing process. However, the bioactive compounds and the molecular mechanism of T. grandis leaf remains unknown. This study aimed to identify bioactive compounds and biological activity contained in T. grandis leaf extract as well as analyze its molecular mechanism in wound-healing process by conducting in silico study using NF-κB, MMP-2, MMP-9, and EGFR-1. Bioactive compounds of T. grandis leaf extract were identified with LC-MS. Three potential compounds, epigallocatechin 3-O cinnamate, epigallocatechin 3-O-p-coumarate, and tectograndinol, were selected based on the Pa score screening with the PASS prediction. Drug-likeness and pharmacokinetics properties of the selected compounds were virtually identified by SwissADME and Protox. The interactions of T. grandis bioactive compounds toward NF-κB, MMP-2, MMP-9, and EGFR-1 were compared to those of curcumin, phenytoin, and nitrofurazone as control. Molecular docking to identify the protein-ligand interaction was performed by Autodock Vina integrated in PyRx v.0.8. Among 82 bioactive compounds detected in the LC-MS analysis, epigallocatechin 3-O-cinnamate, epigallocatechin 3-O-p coumarate, and tectograndinol exhibited anti-inflammatory, antioxidant, free radical scavenger, and MMP-9 inhibitor activities. According to Lipinski’s rule of five, bioactive compounds are possible to be administered as medication. Molecular docking showed that bioactive compounds potentially bound to the active sites of NF-κB, MMP-2, and MMP-9, resulting in proteins inhibition. This study suggested that the wound-healing mechanism of T. grandis bioactive compounds were driven by EGFR-1 stimulation indicated by the ability of bioactive compounds to interact with EGFR-1 in similar manner to those of nitrofurazone. We concluded that bioactive compounds of T. grandis leaf extract has significant potential to be used as traditional wound treatment and therapy. These compounds demonstrated wound-healing activity in silico by interacting with the key molecular targets, including NF-κB, MMP-2, MMP-9, and EGFR-1.
Co-Authors . Waris ., Pujiati Anak Agung Sagung Alit Sukmaningsih Andhita Bagas Rizki Febrianto Andri Wahyu Utomo ANI SULISTYARSI Anindhita, Mentari Nabila Anjarwati, Ardiana Ayu Darmadi Darmadi Darmadi Deny Setiawan Desi Kusumawati Desi Kusumawati Desi Kusumawati Desi Kusumawati, Desi Devina Luthfitasari Dewi Ratih Tirto Sari Diana Citra Septiyani Dwi Rosita Sari Egista Dinka Endang Tri Handayani Eni Nur Fadilah Eni Nur Fadilah, Eni Nur Faradilla Ardheane Gustin Farida Nuraini Farizha Irmawati Farizha Irmawati, Farizha Feni Tin Faizah Gabriella Chandrakirana Krisnamurti Gabriella Chandrakirana Krisnamurti Ghon Lisdiantoro Hartini Hartini Heni Pujiastuti Ima Agung Nurcahyo Ismarisa, Ahilam J Handika Jeffry Handhika Khasanah, Qurul Khasanah Krisnamurti, Gabriella Chandrakirana Laili Nailul Farich Lukas Susanto Lukitasari, Marheny Lukitasari M Lukitasari mahda mumtahanah Mahda Mumtahanah Marheny Lukitasari Mimien Henie Irawati Mohammad Amin Mohammad Arfi Setiawan Mohammad Arfi Setiawan Murni Sapta Sari N K Dewi Nasrul Rofiah H Nasrul Rofiah Hidayati Nurcahyo, Ima Agung Nurdiana, Herning Nurul Kusuma Dewi Pinkan Amita Tri Prasasti Pipit Irmanasari, Pipit Pujiati Pujiati , Pujiati Pujiati Pujiati Puri Ratna Kartini R Hasan R. Bekti Kiswardianta, R. Bekti Rafaella Chandraseta Megananda Rahmawati, Jevi Milda Ramdhani, Alfina Widya Rima Wulan Safitri Rivera, Alice Tonido Rohmania, Elly Roy Putra Safitri, Rusiana Yulia Salsabila, Sintiya Oktavia Sanusi Sanusi Sanusi Sanusi Sari, Dewi Eka Sembiring, Rinawati Siti Marhamatul Sofia Nur Afifah Sudarmiani Sudarmiani Sudarmiani Sudarmiani Sulistyaningrum, Puspa Indah Suproborini, Arum Sutiman B. Sumitro Titin Kuntum Mandalawati TRI RAHAYU Trio Ageng Prayitno Umie Lestari Utomo, Andri Wahyu W Murtafiah W Widiyanto Wachidatul Linda Yuhanna Waris Waris, Waris Wasilatul Murtafiah Weka Sidha Bhagawan Widyawati, Emma Zahroatul Khoirotil Umath, Syamsiyatuz Zahroatul Khoirotil Umath Zainudin Hassan