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All Journal The Journal of Pure and Applied Chemistry Research Journal of Islamic Pharmacy Public Health of Indonesia Industria: Jurnal Teknologi dan Manajemen Agroindustri Jurnal Penelitian Pendidikan IPA (JPPIPA) AcTion: Aceh Nutrition Journal SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan JPSCR : Journal of Pharmaceutical Science and Clinical Research Poltekita : Jurnal Ilmu Kesehatan Majalah Farmasetika JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Ilmiah Jophus: Journal of Pharmacy UMUS Miracle Journal Of Public Health (MJPH) Humanism : Jurnal Pengabdian Masyarakat Jurnal Ilmiah Kesehatan (JIKA) Proceedings Series on Health & Medical Sciences Jurnal Gizi Masyarakat Indonesia (The Journal of Indonesian Community Nutrition) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Mandiri Pharmaceutical Reports Pharmacology And Pharmacy Scientific Journals (PAPS Journals) Indonesian Health Journal MULTIPLE: Journal of Global and Multidisciplinary CERATA Jurnal Medicare Jurnal Sains dan Kesehatan
Saparuddin Latu
Department Of Pharmacy, Pharmacy Faculty, Megarezky University, Jl. Antang Raya No. 43 Makassar, South Sulawesi, Indonesia 90234
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Journal : CERATA

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The Antibacterial Activity Test of Methanol and N-Hexane Fractions of Yellow Pumpkin Fruit Extract (Cucurbita moschata Duch) Against Escherichia coli and Staphylococcus aureus Suleman, Abdul Wahid; Saparuddin Latu; Sriyanty Sadsyam; Safaruddin; Pradila
CERATA Jurnal Ilmu Farmasi Vol 16 No 1 (2025): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v16i1.1370

Abstract

Infectious diseases are still a major health problem in several countries, especially in developing countries. The medication used to treat bacterial infections is obtained by utilizing herbal plants obtained from natural ingredients. Pumpkin fruit extract (Cucurbita moschata) contains flavonoids. tannins, saponins, and alkaloids Pumpkin fruit is effective as an antidiabetic, an antihypertensive, an antitumor, an antibacterial, and an antioxidant. This study aims to determine the antibacterial activity of the methanol and n-hexane fractions of yellow pumpkin (Cucurbita moschata) fruit extract and at what concentration the methanol and n-hexane fractions of yellow pumpkin (Cucurbita moschata) fruit extract can have antibacterial activity against Escherichia coli and Staphylococcus aureus. This research uses laboratory-experimental research methods. Antibacterial testing in this research involved sterilization, making test solutions, and testing. The results of the antibacterial test on the inhibition zone of the methanol fraction of pumpkin fruit against Escherichia coli and Staphylococcus aureus bacteria at concentrations of 20%, 30%, and 40% were in the strong category, while the n-hexane fraction had an inhibition zone in the weak category for Escherichia coli and Staphylococcus aureus bacteria. Conclusion: The methanol and n-hexane fractions have antibacterial activity against Escherichia coli and Staphylococcus aureus, and the concentrations with antibacterial activity are 20%, 30%, and 40%.
Co-Authors Abdul Wahid Suleman Aditya Yudistira Agus Susanto Aisyah Nur Sapriati Aisyah Nur Saptriati Amir, Arfenti Andi Irdawati Andi Muh Yagkin P Andi Muh Yagkin Padjalangi A Andi Muh. Yaqkin P Andi Muhammad Yaqkin Andi Muhammad Yaqkin Padjalangi Asjur, Asti Vebriyanti Asnah Marzuki Aziz, Yuliana Bahar, Muhammad Yusuf Bambang, Ayu Wulansari Baso, Bachtiar Dewi Marhaeni Diah Herawati Firdaus Firdaus Firman, Imran Fitrianingsih, Julia Gaffar, Herry Darsim Gajali, Nurdila Haerawati Idris Haerawati Idris, Haerawati Hasmar, Wahyu Nuraini Hasnany, Hasnany Herman, Sriyana Hilmiati Wahid Ikhsan, Mifta Khaerti Imrawati Jalal, Jalal Jangga Jangga, Jangga Junita, Nurfitria K, Aswanto M Fais Satrianegara Ma'ruf, Irham Mahmudah, Rifa’atul Mamat Pratama, Mamat Mansur Mansur Mansur - Mansur Mansur Mansur Marthen Arie Marwan, Ummi Kalsum Muammar Fawwaz Muhammad Basir Muhammad Basir Muhammad Idris Patarai Muhammad Rifai Musdar, Tamzil Azizi Musliani, Musliani Musnur, Aldha Irjayanti Mustamin Mustarin, Rahmah Nia Putri Citra Ningsih, Nining Ade Nur Afni Ponseng Nurhikmah Nurkamilah, Andi Nurul Inayah Nurwijayanti Obed Rame Padjalangi, Andi Muh Yagkin Padjalangi, Andi Muhammad Yaqkin Pakinde, Ayisti Pasinggi, Adinda Sari Patarai, Muhammad Idris Pradila Putri, Hardyanti Eka R. Rusli Rahayu, Rita Rahmaniah, Rahmaniah Rahmatia Rifa’atul Mahmudah Rika Handayani Risnah Rosdiana Rosdiana Rosdiana Rosdiana Rusli Safaruddin Santi, Elvira Saputro, Syaifullah Satrianegara, Faiz Siti Helmyati Sri Wulan Rini Sriyanty Sadsyam Supardi, Nurjannah Surya Syarifuddin Syahruddin, Akmal Novrian Syamsidar Syamsuriyati, Syamsuriyati Tamira Tansy Timbuleng Wattimena, Jans Goldman Yagkin Padjalangi, Andi Muh Yaqkin-P, Andi Muh. Yulianti Yulis, Dian Meiliani Yunaldi Yunaldi Yuri Pratiwi Utami Zainuddin