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All Journal Jurnal Ekonomi, Bisnis dan Kewirausahaan (JEBIK) Media Penelitian dan Pengembangan Kesehatan e-Journal Pustaka Kesehatan Jurnal Anestesi Perioperatif Journal of Agromedicine and Medical Sciences Global Medical and Health Communication JURNAL PENGABDIAN KEPADA MASYARAKAT JEES (Journal of English Educators Society) Terampil : Jurnal Pendidikan dan Pembelajaran Dasar Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Langkawi: Journal of The Association for Arabic and English NurseLine Journal Journal of Islamic Medicine Al-sihah: The Public Health Science Journal Child Education Journal SCAFFOLDING: Jurnal Pendidikan Islam dan Multikulturalisme Medika Kartika : Jurnal Kedokteran dan Kesehatan Journal of English Language and Pedagogy AL-ADABIYA: Jurnal Kebudayaan dan Keagamaan Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Mitra Mahajana: Jurnal Pengabdian Masyarakat Journal of Social Research Jurnal Pengabdian Pada Masyarakat Indonesia (JPPMI) Asketik: Jurnal Agama dan Perubahan Sosial Journal of Quality Assurance in Islamic Education (JQAIE) e_Jurnal Ilmiah Riset Akuntansi E-JRM Conference Proceedings International Conference on Education Innovation and Social Science Subservire: Jurnal Pengabdian kepada Masyarakat Jurnal Akuntansi Keuangan Dan Perpajakan Jurnal Pendidikan Progresif Menulis: Jurnal Penelitian Nusantara
Erfan Efendi
Fakultas Kedokteran, Universitas Jember Jln. Kalimantan 37, Jember 68121
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : e-Journal Pustaka Kesehatan

 1 
Pengaruh Induksi Racun Ubur-Ubur (Physalia utriculus) terhadap Fungsi Oksigenasi dari Eritrosit pada Mencit Jantan Vita Alfiatul Hasanah; Al Munawir; Erfan Efendi
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Jellyfish is one of the animals that is responsible for poisoning in human. The poisoning jellyfish commonly found is Physalia utriculus. Jellyfish poison is potential to cause hemolysis on blood. The purpose of this study was to determine the influence of jellyfish (Physalia utriculus) poisoning induction toward the oxygenation function of the male mice erythrocytes. The method was true experimental design with post test only control group design. Eight male mice were devided into two groups: control and treatment groups with a dose of jellyfish poison 30 mg/kgBW. The observation was conducted by using a pulse oxymeter. The result showed average level of oxygen saturation in the control group minute 0; 15; 30; 60; 120; 240; 480; 720; 1440 were 55%; 54%; 63,75%; 70%; 65,25%; 67,5%; 65,75%; 72%; 55%, respectively. While in the treatment group were 61,25%; 62,75%; 59,75%; 58,5%; 51,75%; 58%; 57%; 75,75%; 47%, respectively. The statistical bivariate correlation test has a correlation coefficient value (r) 0,383. The significance value is (p) 0,309 (p>0,05). The conclusions of this study was jellyfish (Physalia utriculus) poisoning induction has no significant effect toward the change of oxygenation function of the male mice erythrocytes. Keywords: jellyfish, jellyfish poison (Physalia utriculus), erythrocytes, oxygen saturation
Perbandingan Komplikasi Malunion pada Pasien Fraktur Humerus Pasca Terapi Operatif dan Non-Operatif di RS Bina Sehat Djaya Mario Eri Surya Alfonsus; Muhamad Hasan; Erfan Efendi
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Humerus fracture is a quite common fracture. Fracture of diaphyseal humerus is 1,2 % of all cases of fracture. The treatment of humeral shaft fracture can use 2 different approaches, operative treatment and conservative treatment. This research aimed to compare the complication of malunion in patients with operative and conservative treatment. This was an observational analytic study on patients at the Bina Sehat Hospital. Samples were divided into 2 groups, operative and non-operative. Both groups were examined by measuring the lenght of the humerus after fracture comparing with its contralateral, the ability of the internal rotation, the ability of the external rotation, and angulation inspection. Statistical test showed a difference humerus shortening between 2 groups reached 0.873 cm. The difference between 2 groups on the ability of internal rotation reached 11.4710. The difference between 2 groups on ability of external rotation reached 16.608o. And the result for angulation assessment also showed significant difference between 2 groups. In conclutson, there was a significant difference in complications of malunion between operative and non-operative groups.   Keywords: humerus fracture, operative treatment, non operative treatment, comparative malunion
Analisis In Vivo Aktivitas Antihipertensi dari Protein Biji Melinjo (Gnetum gnemon) Terhidrolisis Yeni Tri Puspitaningrum; Erfan Efendi; Tri Agus Siswoyo
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Hypertension is a serious health problem and requires a good handling. An alternative treatment for hypertension is required due to the treatment of hypertension took a long period of time causing unwanted side effects. Melinjo seed hydrolyzed-proteins have an ACE-inhibitor activity, an antihypertensive effect. This study aimed to determine the antihypertensive effects of melinjo seed hydrolyzed-proteins in hypertensive rats. Wistar rats induced with prednisone 1,5 mg/kg body weight and 2% NaCl for 7 days and then treated. There were 7 groups: a normal group K, a group K(-) which is a hypertensive rats without treatment, a group K(+) which is hypertensive rats with captopril 2,5 mg/kg body weight on day 8th, and four treatment groups P1, P2, P3, and P4 which are hypertensive rats with melinjo seed hydrolyzed-proteins with a dose of 5, 10, 20, and 30 mg/kg body weight on day 8th, respectively. Blood pressure was measured before and after treatment every 1 hour for 5 hours. The results showed that melinjo seed (Gnetum gnemon) hydrolyzed-proteins can decrease blood pressure in hypertensive rats.   Keywords: Antihypertensive, Gnetum gnemon, Hydrolized-Protein, Blood Pressure
Efek Penambahan Vitamin C terhadap Aktivitas Klindamisin dalam Menghambat Pertumbuhan Streptococcus pneumoniae secara In Vitro Bagus Dwi Kurniawan; Dini Agustina; Erfan Efendi
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.9744

Abstract

Pneumonia is one of the lower respiratory tract infection involving respiratory bronchioles and alveoli that mostly caused by Streptococcus pneumoniae.Clindamycin is one of the drug of choice for pneumoniae. This drugs inhibits the growth of S. pneumoniae by producing ROS (Reactive Oxygen Species). Recent study has shown that vitamin C could generate ROS leading to DNA-damage on bacteria. The aims of this study was to know the possible benefit effect of adding vitamin C towards clindamycin inhibition activity against the growth of S. pneumoniae in vitro. This research was conducted by using 7 groups which consist of negative control (aquades), positive control (clindamycin), and test group 1 until 5 that given the combination of clindamycin and vitamin C as follows 2,5 mg/ml; 5 mg/ml; 10 mg/ml; 20 mg/ml; and 40 mg/ml. The inhibition effect of growing S. pneumoniae shown by the inhibition zone diameter. The average of inhibition zone on negative control, positive control, and test group were 5; 24,12; 24,62; 26,08; 27,58; 28,74; and 29,76 mm. These result show a significant correlation based on Pearson test (the coefficient correlation’s result is +0,910). The logarithmic regression revealed the minimal concentration of vitamin C was 1,767 mg/ml. It can be concluded that vitamin C increased the activity of clindamycin by inhibiting the growth of S.pneumoniae in vitro. Keywords: Streptococcus pneumoniae, ROS, Clindamycin, Vitamin C
Pengaruh Ekstrak Albumin Ikan Gabus (Chana striata) terhadap Kadar IFN-γ Pasien Tuberkulosis Paru dengan Pengobatan Fase Intensif (The Effect of Albumin Snakehead Fish (Chana striata) Extract on IFN-Y of Pulmonary Tuberculosis Patients during Intens Henggar Allest Pratama; Erfan Efendi; Rini Riyanti
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Pulmonary tuberculosis is a respiratory infection disease caused by Mycobacterium tuberculosis infection in lung tissue. Mycobacterium tuberculosis could inhibit macrophage activation by inducing an increase of SOCS1 which can inhibit IFN-γ signaling process. Meanwhile, IFN-γ production continues as long as Mycobacterium tuberculosis still exist, so the IFN-γ levels stay high. This study aimed to investigate the effect of albumin snakehead fish (Chana striata) extract to decrease IFN-γ level. The study design was a quasy experimental design. The study subject was 24 tuberculosis patients during intensive phase medication, were divided into 2 groups. Experimental group was given 1500 mg/day albumin snakehead fish (Chana striata) extract while control group was placebo for 30 days. This study showed that albumin snakehead fish (Chana striata) extraxt can decrease significanly IFN-γ levels in the experimental group (p=0.006) but not statistically signicant if compared with the decrease of control group (p=0.061). It can be concluded that albumin snakehead fish (Chana striata) extract in dose of 1500 mg/day had not able to decrease IFN-γ levels of pulmonary tuberculosis patients during intensive phase medication yet.   Keywords: tuberculosis, albumin, snakehead fish, IFN-γ
Pengaruh Induksi Toksin Ubur-ubur (Physalia physalis) terhadap Gambaran Histopatologi Paru-paru Tikus Wistar Sayyidah Auliany Aminy; Al Munawir; Erfan Efendi
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Physalia physalis adalah salah satu jenis ubur-ubur beracun yang dapat menimbulkan dyspnea setelah tersengat. Hal ini menunjukkan adanya efek pneumotoxic toksin Physalia physalis. Penelitian ini bertujuan untuk mengetahui efek pneumotoxic protein toksin ubur-ubur Physalia physalis secara in vivo pada tikus Wistar. Penelitian menggunakan sampel tikus galur Wistar jantan dengan berat rata-rata 150 gram dengan 1 kelompok kontrol (K) dan 3 kelompok perlakuan (P), masing-masing kelompok terdiri atas 6 ekor tikus. Kelompok K diinjeksi dengan larutan PZ; P1, P2 dan P3 masing-masing diinjeksi protein toksin ubur-ubur Physalia physalis dengan dosis 10 mg/KgBB, 20 mg/KgBB dan 30 mg/KgBB. Setelah 6 jam organ paru-paru tikus diambil dan direndam dengan formalin 10% dan dilakukan pembuatan preparat histologi, kemudian dilakukan pengamatan secara mikroskopik dan ditentukan tingkat perubahan histopatologi paru-paru dengan menggunakan skor. Hasil penelitian menunjukkan terjadinya perubahan histopatologi pada paru-paru tikus Wistar berupa infiltrasi sel radang, edema paru, degenerasi dan apoptosis sel-sel penyusun paru. Hasil uji statistik Kruskal-wallis menunjukkan data memiliki perbedaan signifikan (p=0,001). Terdapat perbedaan yang signifikan pada perubahan histologi paru-paru antara kelompok K dengan P1, P2 dan P3. Dapat disimpulkan bahwa toksin ubur-ubur Physalia physalis mempengaruhi gambaran histopatologi paru-paru tikus Wistar.   Kata kunci: Toksin, ubur-ubur, Physalia physalis, Histopatologi, paru- paru.
Co-Authors Ababil, Ressy Yulia Abdul Hamid Aly Abdussyakir Z, Muhammad Ain Yuanita Insani Aishyah, Cholifatul Al Munawir Al’ Azhmi, Arumdhani Aldila Ersaputri Amara, Rosalina Dwi Ana Nihayah Anggrayny, Devrynda Bela Anisa Putri Anisah Rifqotul Istiqomah Anjani Putri Retnaninggalih Anjani Putri Retnaninggalih, Anjani Putri Arifah, Naila Zanubah Arifin, Muhammad Fiqih Syamsul Arista Fauzi Kartika Sari Asnawan, A Astuti, Fitria Afdiyanti Ati, Nurani Damei Azmi Ilmagfiroh Bagus Dwi Kurniawan Bagus Hermansyah Baharudin Rachman Basalamah, Muhammad Ridwan Bintang, Muhammad Farrel Ravidinata Masoga Binti Novita Sari Brilliant Givya Ariansari Budi Eko Soetjipto Chofifah, Cindy Nur Damayanti, Lutfi Desie Dwi Wisudanti Dharmawan, Alif Dharmawan, Dion Krismashogi Dina Helianti Dini Agustina Dion Krismashogi Dharmawan Dita Diana Parti Djaya Mario Eri Surya Alfonsus Dwicahyandari, Winie Septhia Dwita Aryadina Rachmawati Dwiyani Sudaryanti Ekvan Danang Setya Pramudito ENNY SUSWATI Erlin Waridatul Chusna Erma Sulistyaningsih Fadli, Ach. Marzuki Faifatur R, M. Kurma Nur Farid, Mohtazul Febriana, Anita Fitria, Nabila Soviatul Fuad Adi Prasetyo Guntoro, Danang Hairrudin Hairrudin Hariyanto, Eka Harun Alrasyid Hendri Kurniawan, Hendri Henggar Allest Pratama Hutama, Dilyan Ardi Ifadatul Soimah Ika Rahmawati Sutejo Ike Anita, Ike Ita Athia Kahfi Karunia Ilahi Karisma, Yunita Khoirunisa, Dita Dieni Kiky Martha Ariesaka Kiptiyah, Khoirotul Kurnia Anisya Maharani Laila Safira Lisdiana Lisdiana M. Ali Shodikin Mardhiyyah Nurul Hasanah Maslichah, Maslichah MOCH. TAUFIK Moh. Zuinurroziqin Monika Roosyidah Mudzakir Taufiqurrahman Muhamad Hasan Muhammad Ahsanul Imam Munadiyas Silmi Octiyani Najimatul Badi’ah Nastiti Bekti Utami Ni'mah, Dzurriyyatun Nissa, Uswatul Tirania Choirul Nufus, Zakiyatun Nur Diana Nurfahimi, Yudriani Nurhalisa, Siti Nurhayati, Nina Sutrisno Yanti Nurul Hikmah NURUL QOMARIYAH Pradipta, Parahita Purnawan, I Kadek Putri, Ayu Mei Lisa Putri, Berliana Imandari Putri, Deby Septiani Putri, Mileinia Sukoco Putri, Weni Anita Rachmadan, Suci Rahman, Zainor Ramadhan, Firman Aulia Ratnasari, Khurin'in Rayyan, Muhammad Isra Rafidin Rika Selvita Berliana Rini Puji Astuti Rini Riyanti Rosita Dewi Rozzaq, Abd Rumastika, Nindya Shinta Safi’in, Mohammad Safitri, Athiyah Naura Safitri, Sabilla Tian Salsabila, Jihan Rambu Samsul Arifin Sari, Yusnita Putri Sayyidah Auliany Aminy Septyawati, Ratna Sheilla Rachmania, Sheilla Shofiyatul Hasanah Sholihah, Mar'atus Sintia, Iska Sisdayani, Alfina Galuh Hannie Sonia, Selva Fersa Srinin, Wathanan Sugiyanta Sugiyanta Susanti, Diva Dwi Sutikno, Totalenesya Reforrent Sutrisno, Nina Totalenesya Reforrent Sutikno Tri Agus Siswoyo Tsauri, Muhammad Shofyan Ubaidillah, M. Faruq Ubaidillah, Sofwan Roif Via Afkarina Vita Alfiatul Hasanah Wahyuning Ati Ashari Wardatun Nafiah Wildan Khisbullah Suhma Wiratama, Aryasena Reyhan Wiwien Sugih Utami Yeni Tri Puspitaningrum Yudha Nurdian Yulianah, Septa Yunita Armiyanti Zahrah Febianti Zulaikha Rizqina Rahmawati Zulfatun Naimah Zulmida, Emma Sukma