Heri Setiyo Bekti
Department Of Medical Laboratory Technology, Politeknik Kesehatan Kemenkes Denpasar, Denpasar, Bali, Indonesia And Center Of Excelence In Science And Technology, Polytechnic Of Health Denpasar, Bali, Indonesia

Published : 43 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST

Daya Hambat Ekstrak Daun Sirih dan Daun Legundi Terhadap Pertumbuhan Bakteri Staphylococcus aureus Ida Bagus Oka Suyasa; Heri Setiyo Bekti; Luh Putu Rinawati; Luh Putu Laksmi; Putu Diah Wahyuni; Desak Gede Dwi Agustini; Aprilia Rakhmawati
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 5, No 1 (2022): The Journal Of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v5i1.11015

Abstract

Staphylococcus aureus is one of the causes of infectious disease, ranging from mild to severe infections such as meningitis. The drug that is often used is the penicillin class of antibiotics. Apart from chemical antibiotics, natural antibacterial compunds from plants can be also used as an alternative treatment for this infection. Such as green betel (Piper betle L.) and legundi (Vitex trifolia L.). The ethanol extract of betel leaf has antibacterial activity against Staphylococcus aureus. The phytochemical content in legundi leaf is also able to inhibit the growth of Staphylococcus aureus. The ethanol extract of betel leaf and legundi is made through a maceration process. The extract concentrations used in this study were 20%, 30%, and 40%. The inhibition test of Staphylococcus aureus using the disc method. From the results of this study, the active substances found in betel leaf were flavonoids, tannins, and phenols, while in legundi were found flavonoids, tannins and phenols, and quinones. In total, the mean inhibition zone in this study ranged from 7.87mm to 17.33mm where legundi leaf extract was in the moderate category, betel and combination extract were classified as strong. There was a difference in the diameter of the inhibition zone of betel and legundi extract at a concentration 20% with 40%. In the combination extract there is a difference in the concentration of 20% with 40% and 30% with 40%. An antimicrobial compound can be said to synergize if a mixture of two or more antimicrobial compounds is able to provide an effect of each compounds. In this study, it has seen that the mean of the combination is higher than the mean of legundi leaf extract. Meanwhile, the mean of betel leaf extract is still greater than the combination extract.
Co-Authors Ade Dharmawan Agus Sri Lestari Amany, Hana Amirah ANDI UDIN SARANSI Anniwati, Leonita Aprilia Rakhmawati Aprilia Rakhmawati Aprilia Rakhmawati Aprilia Rakhmawati Arjani, Ida Ayu Made Sri Artawa, I Made Budi Arwati, Ketut Lilik Ayu Sukma Wedha Kristyanti Burhannuddin Burhanuddin, Burhannuddin Cok Dewi Widhya Hana Sundari Cok Dewi Widhya Hana Sundari Cok Dewi Widhya HS Cok Dewi Widhya HS Cokorda Dewi Widhya Hana Sundari Desak Gede Dwi Agustini Desak Made Lestari Dewi Dewa Ayu Niti Rahayu Putri Dewi, Ni Km Ayu Kusuma Dewi, Ni Nyoman Astika Dewi, Pande Putu Ayu Patria Dharmawaiswari, Anak Agung Ayu Ratih Dharmawati, I Gst Agung Ayu Farsida, Farsida Fusvita Merdekawati Ganjar Noviar Grace Monica Purwani Ruth Haribaik, Anastaysia Annisa Hasfika, Essydhea Husna, Ismalia I Gusti Agung Ayu Dharmawati I Gusti Agung Ayu Dharmawati I Gusti Agung Dewi Sarihati I Gusti Agung Dewi Sarihati I Gusti Agung Dewi Sarihati I Gusti Ayu Made Wulan Diantari I Gusti Ayu Sri Dhyanaputri I Gusti Ayu Sri Dhyanaputri I Gusti Ngurah Teja Pratama I Made Krishna Paramartha I Made Suarjana I Made Suarjana I Made Yogi Hardiyanta I Nyoman Jirna I Wayan Karta I Wayan Karta Ida Ayu Krisna Dwipayanti Ida Ayu Sri Arjani Ida Bagus Nyoman Putra Dwija Ida Bagus Oka Suyasa Ida Bagus Oka Suyasa Indriyani Indriyani Jannah Sofy Yanty Kadek Ika Surya Cahyani Kosasih, Audia Nizhma Nabila Kurniawan, Surya Bayu Luh Ade Wilan Krisna Luh Ade Wilankrisna Luh Putu Laksmi Mahastuti, Shri Ayu Purnami Mardhia Mardhia Marpaung, Nurasi Lidya E. Mastra , Nyoman Merdekawati, Fusvita Mochamad Choirul Hadi Ni Kadek Wahyu Diana Sari Ni Komang Erny Astiti Ni Komang Juniawati Ni Komang Omik Trianita Udiana Ni Komang Sri Narayanthi Ni Nyoman Astika Dewi Ni Putu Ditya Prabandari Dewi Ni Putu Ditya Prabandari Dewi Ni Putu Intan Maha Ayu Diyanti Ni Putu Lisa Anjani Ni Putu Yulia Rahma Dewi Ni Wayan Rika Kumara Dewi Noviar, Ganjar Nur Habibah Nur Habibah Nyoman Mastra Posmaningsih, Dewa Ayu Agustini Pradnya Yasa, Ni Putu Candra Dewi Prianggandanni, Made Ayu Vita Purwani Ruth, Grace Monica Putu Amrita Paramahita Putu Diah Wahyuni Rakhmawati, Aprilia Rike Syahniar Rinawati, Luh Putu Rindi, Oktavelendi Dhaneta Graha Rofi'ah, Lisa Khofidatur Ruspawan, I Dewa Made Savitri, Ni Putu Ayu Dani Sofi Yanty, Jannah Sudiadnyana, I Wayan Surya Bayu Kurniawan Suwarriana, I Nyoman Astra Suyasa, Ida Bagus Oka Tedja, I Gusti Ayu Wiradari Wikantari, Ni Made Ayu Kerti Wilankrisna, Luh Ade Yanty, Jannah Sofy