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All Journal Buletin Veteriner Udayana Buletin Udayana Mengabdi Jurnal Veteriner Indonesia Medicus Veterinus Jurnal Pengembangan Kota Jurnal Medik Veteriner Martabe : Jurnal Pengabdian Kepada Masyarakat Majalah Farmasetika Jurnal Gema Ngabdi Advances in Tropical Biodiversity and Environmental Sciences Nusantara Science and Technology Proceedings Jurnal Pengabdian Kepada Masyarakat Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Journal of Veterinary and Animal Sciences Jurnal Medika Veterinaria
I Made Merdana
Laboratorium Farmakologi Dan Farmasi Veteriner, Universitas Udayana
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Evaluation of Acute Dermal Toxicity of Hibiscus Leaves as Simplicial Ointment on Albino Rats Saputra, Made Gede Adi Surya; Sudira, I Wayan; Samsuri, Samsuri; Merdana, I Made; Dharmayudha, Anak Agung Gde Oka; Sudisma, I Gusti Ngurah
Jurnal Medik Veteriner Vol. 6 No. 2 (2023): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss2.2023.216-229

Abstract

Hibiscus is a plant that has been shown to contain substances that may be used as sunscreen to protect the skin from UV radiation. In terms of their potential as sunscreens, flavonoids, tannins, and quinone chemicals are crucial because they are antioxidants that can reduce the negative effects of UV radiation and boost photoprotective activity. This study aimed to investigate the acute dermal toxicity potential of hibiscus leaves simplicial ointment 40% on female albino rats. The evaluation method refered to The OECD Guideline for Testing of Chemicals – No. Test: 402, Acute Dermal Toxicity-Fixed Doses Procedure. Based on the Globally Harmonized System compared to this study reported that acute dermal median lethal dose (LD50) was > 2000 mg/kg. It can be concluded that hibiscus leaves simplicial ointment 40% has safe to apply topically and doesn't produce acute skin toxicity.
Sebaceous Adenoma in a Geriatric Poodle Dog: A Case Report Winaya, Ida Bagus Oka; Adi, Anak Agung Ayu Mirah; Sudimartini, Luh Made; Merdana, I Made; Sudipa, Putu Henrywaesa; Pemayun, I Gusti Agung Gde Putra; Sewoyo, Palagan Senopati
Jurnal Medik Veteriner Vol. 7 No. 2 (2024): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol7.iss2.2024.413-419

Abstract

A 14-year-old black male Poodle was brought to the Animal Teaching Hospital, Udayana University by its owner with clinical signs of frequent licking of its left front paw. Upon examination, red bumps were observed on the left front leg, accompanied by small, round black spots scattered on the dorsal side of the body. Additionally, black nodules were present on the lower eyelids and hind limbs. Surgical intervention was undertaken to excise the tumor mass, with the animal under anesthesia induced by ketamine at 5 mg/kg BW intravenously. The reddish nodule was excised by performing an elliptical incision at the base of tumor. Postoperatively, the animal received an antibacterial injection comprising ceftriaxone and tazobactam at 25 mg/kg BW intramuscularly and antiseptic wound dressing for supportive care. Microscopic examination revealed neoplastic cells arranged into lobules of varying sizes and shapes within the tumor mass. These lobules consisted of differentiated sebocytes and basaloid cells. At the periphery of the neoplastic lobules, the basaloid cells displayed several layers and exhibited invasion with moderate anisocytosis. The mitotic index was no more than ten cells in one field of view. Based on these histopathological features, the tumor was confirmed to be a sebaceous adenoma. After a 10-month follow-up period, there were no signs of tumor recurrence observed.
Evaluasi Salep Simplisia Daun Kembang Sepatu yang Memiliki Potensi Terhadap Pertumbuhan Rambut Arinata, I Ketut Teguh; Sudira, I Wayan; Samsuri, Samsuri; Merdana, I Made; Dharmayudha, Anak Agung Gde Oka
Majalah Farmasetika Vol 10, No 2 (2025)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v10i2.59421

Abstract

Berbagai studi mengenai potensi kembang sepatu sebagai tanaman obat yang memiliki pengaruh terhadap pertumbuhan rambut telah dilaporkan. Pada penelitian ini dibuat formulasi sediaan topikal yaitu salep dari simplisia daun kembang sepatu dengan bahan dasar hidrokarbon. Pengujian dilakukan untuk melihat kualitas fisik dari sediaan. Oleh karena itu, penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi simplisia terhadap perolehan kualitas salep yang baik serta melihat potensi pembuatan salep menggunakan bahan dasar simplisia daun kembang sepatu. Simplisia daun kembang sepatu dicampur dengan bahan dasar salep hidrokarbon yaitu vaselin alba sehingga membentuk formulasi dengan konsentrasi simplisia yang bervariasi. Pengujian yang dilakukan meliputi uji organoleptik, uji homogenitas, uji pH, uji daya sebar, uji daya lekat, dan cycling test. Hasil penelitian menunjukkan tidak ada perubahan secara organoleptik, tidak homogen, pH 6 yang sesuai dengan pH kulit, daya sebar di bawa standar menyebabkan konsistensi padat, tiga dari empat formulasi lolos standar daya lekat, dan hasil cycling test menunjukkan semua formulasi stabil pada proses penyimpanan. Berdasarkan hasil penelitian dapat disimpulkan konsentrasi simplisia daun kembang sepatu berpengaruh terhadap kualitas salep. Namun, sediaan salep tersebut belum memenuhi standar homogenitas dan daya sebar.
Pemberdayaan Masyarakat Untuk Pemanfaatan Bambu sebagai Perkuatan Lereng di Desa Guntur Macan Kecamatan Gunung Sari Lombok Barat Mahmud, Fathmah; Hariyadi, Hariyadi; Merdana, Merdana; Ngudiyono, Ngudiyono; Kencanawati, Ni Nyoman; Ali, Ahmad Muhammad
Jurnal Gema Ngabdi Vol. 7 No. 1 (2025): JURNAL GEMA NGABDI
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jgn.v7i1.550

Abstract

Guntur Macan Village is a hilly area located in the Gunung Sari sub-district, West Lombok Regency. The sandy hill soil, characterized by a significant slope, lacks cohesion, making the area prone to landslides, especially during heavy rainfall, flooding, or tectonic earthquakes. Landslides are further exacerbated by soil cracks filled with water, either from rain or other sources, which reduce the safety factor compared to soil without cracks. The closer the cracks are to the sliding surface, the more the safety factor decreases. In Guntur Macan Village and the surrounding areas of Gunung Sari sub-district, bamboo is widely planted. Bamboo, being cost-effective and environmentally friendly, can be utilized as a retaining structure to mitigate landslides. This Community Empowerment Program (PKM) commenced with a location survey conducted two weeks before implementation, followed by a two-day execution phase. On the first day, educational sessions were provided, covering topics such as bamboo cutting, preservation, and the construction of bamboo retaining walls. On the second day, bamboo retaining walls were built on residential land in Guntur Macan Village. Through this PKM activity, the residents of Guntur Macan are now capable of constructing bamboo retaining walls to prevent landslides.
PROGRAM DESA TANGGUH COVID-19 DI DESA PIKAT KABUPATEN KLUNGKUNG PROVINSI BALI Ani, Luh Seri; Arya Utami, Ni Wayan; Sri Darmayani, IGA; Merdana, I Made; Ari Mogi, I Komang
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 7 (2022): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v5i7.2364-2371

Abstract

The Covid-19 pandemic caused health problems in various countries including Indonesia. Various efforts have been made as a strategy to prevent the transmission of Covid-19 including the implementation of restriction on community activity to reduce mobility, implementing health protocols, namely wearing masks, social distancing, washing hands, tests, search, follow-up, and vaccinations.  The Covid-19 resilient village program was organized to raise public awareness about covid-19 infections and how to maintain physical and mental health. The Covid-19 resilient village program was implemented in Pikat Village, Klungkung Regency, Bali Province. The activity took place in July-August 2021. The target of the activity is the entire community in Pikat Village. The activity was carried out by a combination method online and offline in related the Covid-19 pandemic situation and the implementation of restrictions on activities for all communities including in Pikat Village. The Covid-19 resilient village program consists of 5 activities, namely Covid-19 contact trackers, mask waste processing education, mental health education, benefits education as an immunity-enhancing material, distribution of masks and handsanitizers for the community. This activity runs smoothly and provides benefits for the community so that it needs to be maintained the continuity of activities to educate the community in accordance with needs.
Co-Authors Adri Yana Rambu Anawenju Afrizal Choirul Umam Agustina, I Putu Sudana Ali, Ahmad Muhammad Alviana Rizqiyah Utami Anak Agung Ayu Mirah Adi Anak Agung Gde Arjana Anak Agung Gde Arjana Anak Agung Gde Oka Dharmayudha Anak Agung Sagung Kendran Anastasia Bhala Ari Mogi, I Komang Arinata, I Ketut Teguh Ayu Prawitasari Citra Pratama Bina Ichsantya Darmawan, I Wayan Eka Dini Hilary Manullang Diyasa, I Gede Susrama Mas Domingas Pereira DWI SURYANTO Elsa Hidayati Elti Febilani Febrina Cicilia Br Ginting, Febrina Cicilia Firdaus, Ihsanul Franky Samuel Milenyano Chandra Fuady Muslih Gde Jasmara Muda Gea, Octo Berkat Gede Iwan Setiabudi Gede Yuda Darmadi Putra Genta Dhamara Adam Putranto Gusti Agung Rama Wiratama Putra Hariyadi, Hariyadi Hartati, Ruth Dwi Hendrawan, I Wayan Dika Wahyu I Dewa Made Nurja Sadhi I Gusti Agung Gede Putra Pemayun I Gusti Ayu Sri Darmayani I Gusti Ketut Suarjana I Gusti Ngurah Sudisma I Gusti Putu Tovan Mahottama I GustiKetut Suarjana I Kadek Ariyuda Prasetya I Kadek Parnayasa I Ketut Berata I Ketut Berata I Ketut Suada I Ketut Suada I Komang Ari Mogi I Komang Ari Mogi I Made Damriyasa I Made Dira Swantara I Made Dodi Gunawan I Made Dwinata I Made Kardena I Made Oka Riawan I Made Robi I NYOMAN ADI SURATMA I Nyoman Sarsana I Nyoman Suartha I Nyoman Sulabda I Nyoman Sulabda I Putu Agus Hendra Wibawa I Putu Agus Santika Putra I Putu Dwi Komala Putra I Putu Mangku Mariasa I Wayan Sudira I Wayan Wirata Ida Ayu Pasti Apsari Ida Bagus Komang Ardana Ida Bagus Made Oka Ida Bagus Oka Winaya Ika Hartini Hutasoit, Ika Hartini Iwan Harjono Utama Jihadulhaq, Jihadulhaq Kadek Febriana Marta Putra Kadek Teguh Wirasastra Ketut Budiasa Kusuma, Putu Winatha Luh Ani Luh Gde Sri Surya Heryani Luh Made Sudimartini Luh Seri Ani Made Gede Adi Surya Saputra Mahardika, I Gusti Bagus Mahmud, Fathmah Monica Lewinsky Ngudiyono Ngudiyono Ni Kadek Eka Widiadnyani Ni Luh Eka Setiasih Ni Luh Watiniasih Ni Nyoman Kencanawati Ni Wayan Arya Utami, Ni Wayan Arya Ningsih, Adriati NYOMAN DITA PAHANG PUTRA, NYOMAN Nyoman Sumiati Pradipta Hendra Setiawan, Pradipta Hendra Putera, I Gusti Ngurah Dwipayana Putra, I Dewa Agung Made Wihanjana Putra, I Made Arya Udyana Putra, Putu Adi Guna Purwaka Putri, Ayu Chitra Adhitya Putu Devi Jayanti Putu Henrywaesa Sudipa Putu Suastika Rama Adi Putra, Rama Adi Sampurno, Ilham Ade Widya Samsuri , Samsuri Samsuri Samsuri Samsuri Samsuri Samsuri Samsuri Samsuri Saputra, I Dewa Ketut Ari Setyawati, Luh Gede Sewoyo, Palagan Senopati Sis wanto Siswanto, Riefqy Tepu Sri Darmayani, IGA ST Kholifah Nor Azizati Suci Nur Qurani Teja, Putu Tessa Hariys Septianda Theresia Ene Ujan, Katarina Kewa Yoga Eka Prasetyo Yoga Pratama Mambela Sarungallo