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All Journal HAYATI Journal of Biosciences METAMORFOSA Journal of Biological Sciences Jurnal Veteriner Jurnal Biologi Udayana Agrikultura Biotika: Jurnal Ilmiah Biologi Indonesian Journal of Applied Sciences Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Biotropika Quagga Bioeksperimen: Jurnal Penelitian Biologi Pro-Life Jurnal Biodjati Bioma : Jurnal Biologi Indonesia Biosaintifika: Journal of Biology & Biology Education Jurnal Riset Akuakultur Jurnal Kreativitas PKM Indonesian Journal of Limnology Manilkara: Journal of Bioscience Journal of Fisheries & Marine
Desak Made Malini
Departemen Biologi, Fakultas Matematika Dan Ilmu Pengetahuan, Universitas Padjadjaran
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Histological Structure of Male Wistar Rats’ Stomach Fed with Yam Tuber Flour Supplementation Permana, Andre Dian; Kuntana, Yasmi Purnamasari; Malini, Desak Made
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 8, No 3 (2023): October 2023
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v8i3.7166

Abstract

A residential rat might harm human health because it acts as a disease reservoir. It has been many efforts to control this rate using synthetic rodenticide. Nevertheless, synthetic rodenticides broke the environment and made rats resistant. Yam (Dioscorea hispida) tube application on rat’s bite could solve the problem. This study evaluated the histology of male Wistar rats (Rattus norvegicus) fed with bite block supplemented with different yam tuber flour concertation to control residential rat populations. Five different treatments were applied with five replications. The treatments were negative control and brodifacoum 0.005% (positive control), 30%, 50%, and 70% of yam tuber flour. The results show that yam tuber supplementation caused damage to male Wistar rat stomachs, as indicated by mucosal erosion and the presence of inflammatory cells. The statistical test indicated that stomach damage significantly differed among treatments, with the severest damages caused by 50% yam tuber supplementation. It could be concluded that the rat’s bite containing yam tuber flour caused stomach damage, and the feed bite containing 70% yam tuber flour was the most effective. This result proved that yam tuber has good potential as a natural rodenticide to control residential rat populations.
Hematological Profile and Spleen Histology Improvement in Diabetic Rats Treated with PLGA Nanoparticles-Ethanol Extract of Jengkol (Archidendron pauciflorum) Fruit Peel Malini, Desak Made
Biotropika: Journal of Tropical Biology Vol. 10 No. 3 (2022)
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.biotropika.2022.010.03.01

Abstract

Jengkol (Archidendron pauciflorum) fruit peel-ethanol extract (JFP) contains several chemical compounds that act as antioxidant agents and are considered to have the potential to treat chronic disorders such as diabetes mellitus. Plant extract is generally applied in polylactic-co-glycolic acid (PLGA) nanoparticles due to its efficiency in entering the target organs. This study aims to investigate the effect of PLGA nanoparticles-ethanol extract of jengkol fruit peel (PLGA nanoparticle-JFP) on improving the hematological profile and the spleen histology of streptozotocin-induced diabetic rats. The treatment group was divided into six groups: (1) control group, (2) streptozotocin control (STZ); (3) 10 mg/kg BW of glibenclamide (GLB); (4) 770 mg/kg BW of jengkol fruit peel-ethanol extract (JFP1); (5) 110 mg/kg BW of JFP (JFP2); and (6) 770 mg/kg BW PLGA nanoparticle-JFP (PLGA-JFP). PLGA-JFP group showed a significant increase in erythrocytes and leukocytes counts (7.73x106 ± 0.02 cell/mm3 and 9.68x103 ± 3.0 cell/mm3 respectively), a decrease in lymphocytes and neutrophils percentage (66.5%±0.5% and 28±1.4% respectively) compared to the STZ group, and no significant difference in monocyte, eosinophils, and basophils percentage within groups. On the spleen histology, the white pulp diameter and the red pulp area showed significantly smaller (168.31±10.69μm and 8,01.28± 480.33 μm2 respectively) compared to the STZ group. Almost all parameters showed no significant difference compared to the GLB group but are significantly different from the control group. The administration of PLGA nanoparticle-JFP was proven to reverse hematological parameters and improve the spleen histology but has not yet reversed the diabetic rats’ condition back to normal.
KONSUMSI OKSIGEN IKAN PELAGIS DI MUARA SEGARA ANAK, TAMAN NASIONAL ALAS PURWO Malini, Desak Made; Muliani, Reni
Bioeksperimen: Jurnal Penelitian Biologi Vol 2, No 2: September 2016
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v2i2.2489

Abstract

Taman Nasional Alas Purwo (TNAP) merupakan salah satu protected area yang ditetapkan sebagai kawasan untuk melestarikan keanekaragaman hayati dan ekosistem. Untuk mencapai tujuan tersebut maka perlu diadakan monitoring tentang kondisi dari kawasan tersebut, yaitu dengan cara mengamati biota perairan seperti ikan pelagis yang habitatnyadi sungai Segara Anak. Kelangsungan hidup ikan ditentukan oleh kondisi lingkungan dan kemampuan ikan untuk menggunakan oksigen dari lingkungannya. Tujuan dari penelitian ini adalah untuk mengetahui jumlah konsumsi oksigen ikan pelagis yang hidup di muara Segara Anak TNAP. Metode yang digunakan adalah observasi. Parameter yang diukur adalah konsumsi O2, kondisi fisik dan kimia dari habitat ikan. Hasil penelitian menunjukkan terdapat 4 jenis ikan pelagis dengan masing-masing konsumsi O2 sebagai berikut Scatophagus argus (0,15 mg/l /h), Toxotes jaculatrix (0,052 mg/l/h), Nectamia fusca (0,052mg/l/h) dan Ambassis macracanthus (0,095 mg/l/h). Tingkat konsumsi oksigen tertinggi ditunjukkan oleh S. argus. Hasil pengukuran parameter fisik dan kimia air adalah sebagai berikut: suhu 28oC, salinitas 33,3%; pH 8; dan oksigen terlarut 5 mg/l, sedangkan suhu udara 30,67oC. Tingkat konsumsi oksigen ikan tergantung pada jenis spesies, ukuran, dan kondisi fisik air.
Treatment of PLGA Nanoparticles Ointment-Ethanol Extract of Archidendron pauciflorum in the Wound Healing in Diabetic Mice Malini, Desak Made; Kuntana, Yasmi Purnamasari; Madihah, Madihah; Furqon, Wildanul; Hermawan, Wawan
Jurnal Biodjati Vol 5 No 2 (2020): November
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v5i2.9256

Abstract

Diabetic wounds lead to severe tissue damage and are diffi-cult to cure. Jengkol (Archidendron pauciflorum) is a plant commonly used by local Indonesian communities to treat diabetic wounds. The efficiency of herbal medicine still has a deficiency of its ability to reach the target organs, therefore nanotechnology is applied in the hope that all drug concentrations can reach the target organs successfully. This study aimed to evaluate the effectiveness of PLGA nanoparticle ointment-ethanol extract jengkol fruit peel (EEJFP) to accelerate the wound healing process in the skin of streptozotocin-induced diabetic mice. The research method used was experimental with a completely randomized design using six treatments and four replications. Diabe-tes was induced by intraperitoneal injection of streptozotocin 180 mg/ kg BW. Mice with a blood glucose level of ≥150 mg/dL were used for diabetic mice models. The incision wound created at the dorsolateral region of shaven skin at ±1 cm2 using sterile scissors. The treatments given were vaseline for Control Negative (CN) and Control Positive (CP), Betadine ointment (PB), 10% EEJFP ointment (P1), 5% PLGA nanoparticle ointment-EEJFP (P2), and 2.5% PLGA nanoparticle ointment-EEJFP (P3). The results showed that the administration of PLGA nanoparticles ointment-EEJFP with a concentration of 5% PLGA nanoparticle ointment-EEJFP (P2) resulted in the shortest wound length on day 3, 7 and 14; narrower granulation tissue; a larger number of blood capillaries; and denser collagen fibers (α <0.05) compared to CP and PB treatments. The administration of PLGA nanoparticle ointment-EEJFP with a concentration of 5% was the most effective concentration in accelerating wound healing in the skin of diabetic mice. 
The analysis of natural forage of blue swimming crab (Portunus pelagicus Linnaeus, 1758) on the east coast of Pangandaran, West Java Sofia Dorothy; Malini, Desak Made
Bioma Vol. 20 No. 1 (2024): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/Bioma20(1).2

Abstract

Continuous use of blue swimming crab (Portunus pelagicus) without any control can cause population decline which leads to damage to the stability of the marine ecosystem, especially in East Coast Pangandaran, therefore cultivation is needed. In aquaculture, it is necessary to provide the right feed by knowing its natural diet. This study aimed to determine the natural diet of blue swimming crabs. The method used was descriptive analysis. The parameters observed were carapace width, gastric weight, the composition of natural diet. The relationship between the carapace width and gastric weight was analyzed by simple regression while the main type of natural diet was known by calculating the percentage of food composition. The relationship between carapace width and gastric weight was positive. Based on the composition found in crab gastric, there were 5 types of natural foods consisting of crustaceans (28.35%), meat (25.37%), mollusk (18.65%), fish (15.67%), and undefined material (UM) (4.47%). It is revealed that crabs are carnivores and scavengers, pose significant relationship between their size and gut content weight. It was also found that the composition of female crab feed was generally higher than that of males.
Co-Authors . SUNARDI Adam Robisalmi, Adam Adnin Laila Amalia Shalihah Andi Perdana Anggraeni, Fajar ANNISA JOVIANI ASTARI Artati, Diah Asep Sopian Azalea Putri Bisri Mustofa Camellia Panatarani Damanhuri, Joni Haryadi Dea Rahman Khairunnisa Dita Aprila Khoirunnisa Dwi Rahmi Dzikrina Syahidah, Dzikrina Elsa Dwi Fauzany Emay Maulani Emilie Nuraida Erawan Fajar Anggraeni Fajar Anggraeni Firda Mohammad Firdous Furqon, Wildanul Hary Krettiawan Hikmat Kasmara I Made Joni Iin Supartinah Ikhsan Khasani Imron Imron Imron Imron, Imron Indriani Sasmita Johan Iskandar Joko Kusmoro Joko Kusmoro Kabul Fadilah Kamilawati, Fitri Kartiawati Alipin KEUKEU KANIAWATI Keukeu Kaniawati Rosada Khairul Syahputra, Khairul Kuntana, Yasmi Purnamasari Listiyowati, Nunuk Madihah Madihah Madihah Madihah Madihah Madihah Madihah Madihah Madihah Madihah Madihah Madihah, Madihah Melanie Melanie Melanie Melanie, Melanie Mia Miranti Rustama Miranti Ariyani Muliani, Reni Muliani, Reni Nadia Istiqomah Nana Media Nia Rossiana Nining Ratningsih Nining Ratningsih Nining Ratningsih Nining Ratningsih Nurullia Fitriani Octaviani, Regita Perdana, Andi Permana, Andre Dian Putri, Deviana Aulia Rani Maharani Reni Muliani Resty Agustin Ruly Budiono Sairandri Dyah Harjanti, Sairandri Dyah Sofia Dorothy SRI WULANDARI sunardi sunardi Supartinah, Iin Syifa Yolanda TEGUH HUSODO TEGUH HUSODO Tia Setiawati Tia Setiawati Tia Setiawati Tri Dewi K. P Tri Dewi Kusumaningrum Pribadi Tri Mayanti Virita Rossa Pratiwi Vita Novianti Wahyu Pamungkas Wawan Hermawan Wawan Hermawan Wawan Hermawan Wawan Hermawan Wawan Hermawan Wildanul Furqon Yasmi Purnamasari Kuntana