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All Journal HAYATI Journal of Biosciences Agrikultura Biotika: Jurnal Ilmiah Biologi Indonesian Journal of Applied Sciences Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Biotropika Quagga Bioeksperimen: Jurnal Penelitian Biologi Pro-Life Jurnal Biodjati Bioma : Jurnal Biologi Indonesia Biosaintifika: Journal of Biology & Biology Education Jurnal Riset Akuakultur Jurnal Kreativitas PKM Manuju : Malahayati Nursing Journal Indonesian Journal of Limnology Manilkara: Journal of Bioscience Journal of Fisheries & Marine
Desak Made Malini
Departemen Biologi, Fakultas Matematika Dan Ilmu Pengerahuan Alam, Universitas Padjadjaran
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Treatment of PLGA Nanoparticles Ointment-Ethanol Extract of Archidendron pauciflorum in the Wound Healing in Diabetic Mice Malini, Desak Made; Kuntana, Yasmi Purnamasari; Madihah, Madihah; Furqon, Wildanul; Hermawan, Wawan
Jurnal Biodjati Vol 5 No 2 (2020): November
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v5i2.9256

Abstract

Diabetic wounds lead to severe tissue damage and are diffi-cult to cure. Jengkol (Archidendron pauciflorum) is a plant commonly used by local Indonesian communities to treat diabetic wounds. The efficiency of herbal medicine still has a deficiency of its ability to reach the target organs, therefore nanotechnology is applied in the hope that all drug concentrations can reach the target organs successfully. This study aimed to evaluate the effectiveness of PLGA nanoparticle ointment-ethanol extract jengkol fruit peel (EEJFP) to accelerate the wound healing process in the skin of streptozotocin-induced diabetic mice. The research method used was experimental with a completely randomized design using six treatments and four replications. Diabe-tes was induced by intraperitoneal injection of streptozotocin 180 mg/ kg BW. Mice with a blood glucose level of ≥150 mg/dL were used for diabetic mice models. The incision wound created at the dorsolateral region of shaven skin at ±1 cm2 using sterile scissors. The treatments given were vaseline for Control Negative (CN) and Control Positive (CP), Betadine ointment (PB), 10% EEJFP ointment (P1), 5% PLGA nanoparticle ointment-EEJFP (P2), and 2.5% PLGA nanoparticle ointment-EEJFP (P3). The results showed that the administration of PLGA nanoparticles ointment-EEJFP with a concentration of 5% PLGA nanoparticle ointment-EEJFP (P2) resulted in the shortest wound length on day 3, 7 and 14; narrower granulation tissue; a larger number of blood capillaries; and denser collagen fibers (α <0.05) compared to CP and PB treatments. The administration of PLGA nanoparticle ointment-EEJFP with a concentration of 5% was the most effective concentration in accelerating wound healing in the skin of diabetic mice. 
The analysis of natural forage of blue swimming crab (Portunus pelagicus Linnaeus, 1758) on the east coast of Pangandaran, West Java Sofia Dorothy; Malini, Desak Made
Bioma Vol. 20 No. 1 (2024): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/Bioma20(1).2

Abstract

Continuous use of blue swimming crab (Portunus pelagicus) without any control can cause population decline which leads to damage to the stability of the marine ecosystem, especially in East Coast Pangandaran, therefore cultivation is needed. In aquaculture, it is necessary to provide the right feed by knowing its natural diet. This study aimed to determine the natural diet of blue swimming crabs. The method used was descriptive analysis. The parameters observed were carapace width, gastric weight, the composition of natural diet. The relationship between the carapace width and gastric weight was analyzed by simple regression while the main type of natural diet was known by calculating the percentage of food composition. The relationship between carapace width and gastric weight was positive. Based on the composition found in crab gastric, there were 5 types of natural foods consisting of crustaceans (28.35%), meat (25.37%), mollusk (18.65%), fish (15.67%), and undefined material (UM) (4.47%). It is revealed that crabs are carnivores and scavengers, pose significant relationship between their size and gut content weight. It was also found that the composition of female crab feed was generally higher than that of males.
Co-Authors . SUNARDI Adam Robisalmi, Adam Adnin Laila Amalia Shalihah Andi Perdana Anggraeni, Fajar ANNISA JOVIANI ASTARI Artati, Diah Asep Sopian Asep Sopian Azalea Putri Bisri Mustofa Camellia Panatarani Damanhuri, Joni Haryadi Dea Rahman Khairunnisa Dita Aprila Khoirunnisa Dwi Rahmi Dzikrina Syahidah Dzikrina Syahidah, Dzikrina Elsa Dwi Fauzany Emay Maulani Emilie Nuraida Erawan Fajar Anggraeni Fajar Anggraeni Fajar Anggraeni Firda Mohammad Firdous Fitri Kamilawati Furqon, Wildanul Hary Krettiawan Hikmat Kasmara I Made Joni Iin Supartinah Ikhsan Khasani Ikhsan Khasani Imron Imron Imron Imron Imron Imron, Imron Indriani Sasmita Johan Iskandar Johan Iskandar Joko Kusmoro Joko Kusmoro Joko Kusmoro Joni Haryadi Damanhuri Kabul Fadilah Kamilawati, Fitri Kartiawati Alipin Kartiawati Alipn KEUKEU KANIAWATI Keukeu Kaniawati Rosada Khairul Syahputra Khairul Syahputra, Khairul Listiyowati, Nunuk Madihah Madihah Melanie Melanie Melanie Melanie, Melanie Mia Miranti Rustama Miranti Ariyani Muliani, Reni Muliani, Reni Nadia Istiqomah Nana Media Nia Rossiana Nining Ratningsih Nurullia Fitriani Nurullia Fitriani Octaviani, Regita Perdana, Andi Permana, Andre Dian Putri, Deviana Aulia Rani Maharani Reni Muliani Resty Agustin Ruly Budiono Sairandri Dyah Harjanti Sairandri Dyah Harjanti, Sairandri Dyah Sofia Dorothy SRI WULANDARI sunardi sunardi Supartinah, Iin Syifa Yolanda Teguh Husodo Tia Setiawati Tri Dewi K. P Tri Dewi Kusumaningrum Pribadi Tri Mayanti Virita Rossa Pratiwi Vita Novianti Wahyu Pamungkas Wawan Hermawan Wawan Hermawan Wawan Hermawan Wildanul Furqon Yasmi Purnamasari Kuntana