Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Jurnal Biomedika dan Kesehatan

The Perbedaan Jumlah Blast pada Hitung Manual dengan Alat Hematologi Siemens Advia 2120i Mario, Mario; PB, Notopuro
Jurnal Biomedika dan Kesehatan Vol 6 No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.186-195

Abstract

Background The development of sophisticated automated blood-cell analyzers caused the proportion of bloodcount samples requiring a manual different count to diminish steadily. Blood smear remains a crucial diagnostic aid in determining the type of leukemia by the appearance and blast numbers in blood smear. Siemens ADVIA 2120i has a parameter of blast cell percentage. This study was undertaken to determine the difference in blast number between manual count and Siemens ADVIA 2120i automatic hematology analyzer. Methods This was an analytical observational study with a cross-sectional design. Thirty samples (22 peripheral blood and eight bone marrow) detected blast numbers from Siemens ADVIA 2120i were examined. Samples were collected from November 2015 to August 2016. A manual count was performed on each sample using a blood smear and bone marrow evaluation. Results Twenty-three cases of AML and 7 cases of ALL were found. Blast percentage from the manual count was between 0 to 95% (Mean 28.5%); from Advia 2120i was between 0.1 to 99% (Mean 16.2%). There was a significant difference in conformity results from blast number between manual count and Siemens ADVIA 2120i with p<0.05. Discussion The difference in blast numbers between manual count and Siemens ADVIA 2120i could be caused by: (1) in manual count, determining blast cells is based on cytoplasm characteristics, granules, nuclear cells, nuclear chromatin, and nucleoli. (2) in ADVIA 2120i, determining blast cell is based on complexity and resistance from BASO reagent. Conclusion Blast numbers were significantly different between manual count and Siemens ADVIA 2120i.
Suspek Atresia Bilier Dengan Infeksi Cytomegalovirus dan Malaria : Infeksi Menular Lewat Transfusi Darah? Mario, Mario; Mashabi, Yasmine; Hairunisa , Nany
Jurnal Biomedika dan Kesehatan Vol 7 No 2 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.237-244

Abstract

Introduction: Blood transfusion can cause infectious complications through transfusion of microbes present in asymptomatic donor blood and/or contamination of stored blood products such as Hepatitis B, Hepatitis C, HIV, syphilis, malaria, Cytomegalovirus (CMV) infection. The risk of infection increases with the amount of blood products transfused.  Case presentation: A 5-month-old boy who had never been to malaria endemic area with jaundice and abdominal enlargement since two months ago, fever since one month ago, and icteric sclera. Data from laboratory results shows anemia, leukocytosis, hyperbilirubinemia, elevated liver enzyme, positive IgM and IgG anti-CMV. Blood smear evaluation:  Trophozoite and ring forms of malaria parasites. Abdominal USG: Type-I Biliary atresia, Choledochal cyst, splenomegaly, ascites, and right pleural effusion. Discussion: An acute Transfusion-transmitted CMV infection in high-risk patients can have severe complications such as billiary atresia, myocarditis, retinitis, encephalitis, or encephalopathy. Leucodepleted blood products for transfusion can reduce the risk of infection. Thick and thin blood smears which is the gold standard for diagnosing malaria, cannot be used for donor screening. Asymptomatic malaria infections may remain undetected. Conclusion: Blood transfusion screening for infectious diseases is still very limited for Hepatitis B, Hepatitis C, Syphilis, and HIV. It is necessary to think about blood transfusion screening for other infectious diseases, such as CMV and malaria, especially in endemic areas, to prevent the occurrence of transfusion-transmitted infection.
Co-Authors A.A. Ketut Agung Cahyawan W Adharamadinka, Muhammad Agung Danur Widyaputra, I Gusti Ahdi, Muhammad Aufil Ahmad Rusdi Aldrino, Aldrino Alvina Alvina Amirullah -, Amirullah Amsal, Bahrul Ananda, Ahmad Rafi Hanif Andi Aco Agus, Andi Aco Anggar Erdhina Adi Anggaraksa Wiprahutama, Farrel Anniza K, Nur Alia Ariandi, Syafina Zaskia Ariq, Muhammad Aris Rahmansyah Avidy, Robbyan Banuaji, Salsabil Zharfa Bayuaji, Lalu Drasca Binekas, Nauval Boni Pahlanop Lapanporo Bustam, Bustam Defritama, Rafly Dwi Rahadianto, Irfan Falatehan, Falatehan Fauziyyah, Fakhirah Ferina, Mutiara Fida Oktavia, Alya Hadian Satria Utama Hairunisa , Nany Handini, Delvi Poppy Hani Dewi Ariessanti Hanifa Humaira, Amanda Hara Wikrama, Anak Agung Gde Hargiani, Fransisca Xaveria Haris, Andi Muhammad Arif HASNAWI HARIS, HASNAWI Idrus, Idham Irwansyah Ilmy, Miftahul Imran Siswadi, Imran Irawan, Musfira Putri Irfan Dwi Rahadianto Ismail, Ashari Jumadi Jumadi Jusnawati, Jusnawati Kalandaraputra Keswani, Heykhal Khalipty Shauma, Nakita Khayyira, Salsabila Winra Laksmi Maharani Lie Tanu Merijanti, Lie Tanu Mandra, Mohammad Ahsan S. Mashabi, Yasmine Muh Nasrullah, Muh Muhammad Aksha Wahda Muhammad Guntur, Muhammad Novalisa, Yoan Melliana Nurwijayanti Kusumaningrum Okolie, Ugo Chuks PB, Notopuro Permadi, Jibril Satrio Pratama, Muhammad Rifki Primadi, Albert Yudi Primahana, Gian Pusparini Pusparini Putra Wansa, Rafif Rajendra Putri Manik, Angelina Qatrunnada, Sekardilla Nur Aisyah Rahandito, Irfan Dwi Rahim, Hariashari Rahman, Luthfi Nur Ras, Atma Riri Amandaria Riska Damayanti, Riska Rizky Prima, Sylvia Rully Ayu Nirmalasari, Rully Ayu Rully Sumarlin Saifuddin Saifuddin Salwia, Salwia Samatha, Felisca Satrio, Annisa Salsabilla Azharia Sihombing, Stephanie Jessie Margaret Siraj, Muhammad Luthfi Suedi, Reski Sunaniah Surjadi, Lily Marliany Tampubolon, Naomi Oktavia Tiara Radinska Deanda Ulfa Utami Mappe Usman, Musrayani Utami, Ayu Puspita Jurnalis Wachyu, Kyra Labiqa Wibisono Prayitno, Baihaqi Yohanes, Jonathan