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Relationships between Smoking, Age, Body Mass Index, and Abstinence with DNA Fragmentation Index in Male Infertile Patients Ediningtyas, Atifa Nadira; Laqif, Abdurahman; Melinawati, Eriana; Respati, Supriyadi Hari
Journal of Maternal and Child Health Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (34.653 KB) | DOI: 10.26911/thejmch.2022.07.04.04

Abstract

Background: Low birth weight (LBW) is defined as a newborn baby weighing less than 2500 grams. Low birth weight is a serious condition in developing countries. The impact of cigarette smoke on pregnant women who are exposed to cigarette smoke is at a higher risk of complications, such as miscarriage, premature birth, or babies born with low weight. This study aims to analyze the relationship between exposure to secondhand smoke and low birth weight. Subjects and Method: This research is a systematic review and meta-analysis by systematically reviewing primary articles from Pubmed, Google Scholar, Scient Direct and Springerlink by selecting articles published in 2012-2022. The articles searched using PICO were P: Pregnant women, I: exposed to cigarette smoke, C: not exposed to cigarette smoke, O: low birth weight. Keywords "Exposure to smoking pregnant women" OR "Expectant mother" OR "Pregnancy women" OR "Exposed to cigarettes" OR "Secondhand smoke exposure" OR "Cigarette smoke expo- sure" AND "Low birth weight" OR "Low weight babies" AND “Case control” AND “Adjusted odds ratio”. Articles used PRISMA flow diagrams and analyzed using Review Manager 5.3. Results: There were nine articles analyzed consisting of Nepal, Morocco, Ethiopia, Sierra Leone, India, Indonesia and China. Meta-analysis showed that cigarette smoke exposure increased the risk of low birth weight and was statistically significant (aOR = 2.19; 95% CI = 1.58 to 3.03; p < 0.001). Conclusion: Exposure to cigarette smoke increases the risk of weight gain in LBW infants by 2.19 times compared to not exposed to cigarette smoke. Keywords: exposure to cigarette smoke, low birth weight, meta-analysis. Correspondence:Winei Handriani. Master’s Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Jawa Tengah. Email: wineihandriani02@gmail.com. Mobile: 083150000253.
The success rate of intrauterine insemination in sperm preparation swim-up method at room temperature compared to the incubator temperature Eriana Melinawati; Uki Retno Budihastuti; Mulyoto Pangestu; Teguh Prakosa; Affi Angelia Ratnasari; Abdurahman Laqif; Darto; Cahyono Hadi; Lunardhi Susanto; Metanolia Sukmawati; Rakano Kautsar Dwiyana; Alfi Marita Tristiarti; Abida Zuhra Jatiningtyas
Majalah Obstetri & Ginekologi Vol. 31 No. 1 (2023): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V31I12023.11-16

Abstract

HIGHLIGHTS There were no significant differences in TMSC, sperm motility, sperm morphology, and DFI in sperm preparation using the swim-up method at 27°C and 37°C. However, this study provided an overview of the average improvement of DFI at 27°C compared to 37°C. There was no significant difference in the pregnancy rate of IUI in sperm preparation using the swim-up method at 27°C and 37°C.   ABSTRACT Objective: This study aimed to determine the effect of temperature during sperm preparation on total sperm motile count (TMSC), sperm motility, sperm morphology, DNA fragmentation index (DFI), and pregnancy rate. Materials and Methods: A quasi-experimental laboratory study with pre- and post-test control group was conducted at Sekar Fertility Clinic, Dr. Moewardi General Hospital, Surakarta, Indonesia. A total of 20 sperm samples from infertile patients were prepared using the swim-up method at 27°C (group 1) and 37°C (group 2). TMSC, motility, morphology, and DFI examinations were performed. In addition, IUI was performed to confirm pregnancy rate. Sperm DNA fragmentation was determined using Sperm Chromatin Dispersion/SpermFunc DNAf test. Sperm DNA fragmentation was characterized by a halo <30% of the volume of the sperm head. Results: Group 1 had mean TMSC of 13.77 ± 9.30, while group 2 had 14.82 ± 8.82; p=0.218. Group 1 had a motility value 82.25+12.77 and group 2 had 82.55 ± 11.69; p=0.968. The morphological value for group 1 was 11.25 ± 5.15 and group 2 was 11.6 ± 5.34; p=0.626. The mean DFI for group 1 was 17.79 ± 10.88 and group 2 was 18.18 ± 12.95; p=0.765. Pregnancy rate in group 1 was 10% and group 2 was 20%; p=1.000. Conclusion: There were no significant differences in TMSC, sperm motility, sperm morphology, DFI, and pregnancy rate in sperm preparation using the swim-up method at 27°C and 37°C.
Perbedaan Kecemasan dan Kualitas Hidup Wanita Menopause di Wilayah Rural dan Urban Alfi Marita Tristiarti; Uki Retno Budihastuti; Eriana Melinawati; Abdurahman Laqif
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 9 No. 3 (2022): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v9i3.304

Abstract

Menopause merupakan proses alamiah pada wanita terkait dengan penuaan. Proses tersebut berdampak terhadap turunnyakualitas hidup atau Quality of Life (QoL) para wanita menopause akibat beragam gejala baik fisik maupun kejiwaankhususnya peningkatan kecemasan. Kecemasan saat menopause dipengaruhi oleh banyak hal seperti ada tidaknyasindrom menopause, tingkat pengetahuan dan wilayah demografi. Penilitian ini bertujuan untuk mengetahui perbedaanderajat kualitas hidup dan tingkat kecemasan pada wanita menopause di wilayah rural dan urban. Penelitian inimenggunakan desain penelitian observasional analitik dengan pendekatan cross-sectional yang dilakukan di wilayah rural(pedesaan) dan urban (perkotaan). Besar sampel adalah 100 wanita menopause yang tinggal di wilayah rural dan 100wanita menopause bertempat tinggal di wilayah urban yang dipilih melalui fix disease sampling. Pengambilan data padapenelitian ini menggunakan alat bantu kuesioner yang telah diuji validitas dan reliabilitasnya. Uji statistik yang digunakanuji Chi-Square. Penelitian menunjukkan bahwa tidak terdapat perbedaan antara tingkat kecemasan antara wanitamenopause di wilayah rural dengan urban dengan nilai signifikansi p = 0,561. Penelitian menunjukkan tidak terdapatperbedaan derajat kualitas hidup antara wanita menopause rural dengan wanita menopause urban, baik pada domainOccupational QoL ( p = 0,544), Health QoL (p = 0,670), Sexual QoL (p = 0,247), dan Emotional QoL (p = 0,753).Hasil penelitian menunjukkan bahwa tidak terdapat perbedaan tingkat kecemasan dan kualitas hidup pada wanitamenopause yang bertempat tinggal di rural dengan wanita menopause yang bertempat tinggal di urban.
Seminar Tatalaksana Infertilitas dan Sistem Rujukan: IIDI Sebagai Pilar Penyuluhan Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Darto; Anggraeni, Asih; Wijayanti, Agung Sari; Hafiizha, Attahira Amalia
Jurnal Abdidas Vol. 5 No. 4 (2024): August, Pages 301 - 449
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v5i4.964

Abstract

Informasi mengenai infertilitas serta tatalaksana dan sistem rujukan merupakan komponen penting dalam pengobatan infertilitas. Ketidakadekuatannya dapat mempengaruhi pasangan dalam menjalankan perawatan. Tujuan dari seminar ini adalah untuk meningkatkan wawasan masyarakat umum mengenai berbagai prosedur tatalaksana infertilitas seperti bedah laparoskopi, histeroskopi, prosedur inseminasi buatan, dan sistem rujukan infertilitas. Seminar dilakukan secara luring bekerja sama dengan organisasi IIDI sebagai jembatan informasi. Tingkat pengetahuan peserta dinilai berdasarkan nilai pre-test dan post-test. Peserta diberikan pre-test sebelum seminar dan post-test setelahnya. Fokus seminar mencakup bedah laparoskopi dan histeroskopi, prosedur inseminasi buatan intrauterin, hingga sistem rujukan infertilitas secara umum. Hasil pre-test dan post-test dianalisis menggunakan uji normalitas Kolmogorov-Smirnov dan uji Wilcoxon. Hasil dari Uji Wilcoxon menunjukkan peningkatan signifikan pada nilai post-test dibanding pre-test (p<0.001). Sebanyak 63 (56.7%) partisipan mengalami peningkatan nilai post-test, 47 (42.3%) partisipan memiliki nilai yang tetap, dan hanya 1 (1%) partisipan mengalami penurunan nilai. Kesimpulan: terdapat perbedaan signifikan antara nilai pre-test dan post-test, menunjukkan bahwa partisipan dapat memahami penjelasan yang diberikan oleh pembicara. Seminar ini terbukti sebagai sarana yang efektif untuk meningkatkan pengetahuan mengenai tatalaksana infertilitas.
Edukasi Skrining COVID-19 pada Program Teknologi Reproduksi Berbantu di Era Pandemi COVID-19 Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; Darto, Darto; Ratnasari, Affi Angelia; Anggraeni, Asih
Jurnal Pengabdian Masyarakat: Darma Bakti Teuku Umar Vol 5, No 2 (2023): Juli-Desember
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/baktiku.v5i2.7064

Abstract

In the era of the coronavirus disease 2019 (COVID-19) pandemic, COVID-19 screening education is essential for the general public, especially for those who undergo assisted reproductive technology (ART) programs. Understanding the preventive measures and precautions of COVID-19 during the treatment process is necessary. Health care staff must also understand the importance of proper COVID-19 screening and control measures. This educational activity is in the form of a YouTube live streaming program that can be followed by the general public, including infertile couples who want to know about infertility, examination procedures, COVID-19 screening guidelines, and the TRB program. Education about COVID-19 screening can minimize stigma and enhance public confidence in the screening procedures. The results of this educational delivery make the general public, especially couples who will undergo the ART program, ready and have the ability to undergo COVID-19 testing, services, and screening. In addition, by providing education and implementing effective screening, we can work together to combat the COVID-19 pandemic and ensure that people receive quality and safe health services.
Kolaborasi Tenaga Medis dan Masyarakat dalam Mendukung Layanan Infertilitas Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; ., Darto; Ratnasari, Affi Angelia; Anggraeni, Asih; Wijayanti, Agung Sari
Jurnal Abdidas Vol. 5 No. 6 (2024): Desember
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v5i6.1066

Abstract

Kolaborasi antara tenaga medis dan masyarakat memiliki peran penting dalam mendukung penanganan infertilitas, sebuah kondisi yang sering menyebabkan kecemasan, stres, dan dampak negatif lainnya pada kesehatan mental. Tenaga medis berperan dalam diagnosis, perencanaan pengobatan, dan mendukung pasien mencapai tujuan mereka untuk memiliki anak, sementara masyarakat dapat memberikan dukungan emosional yang membantu mengurangi isolasi dan depresi pasien. Kegiatan pengabdian ini berfokus pada edukasi dan pemberdayaan tenaga medis serta masyarakat untuk meningkatkan pemahaman dan kapasitas mereka dalam mendukung individu dengan infertilitas. Evaluasi menggunakan pre-test dan post-test menunjukkan bahwa 25% peserta mengalami peningkatan pengetahuan setelah kegiatan, sementara 72% telah memiliki pemahaman yang memadai sebelumnya. Hasil ini menggambarkan efektivitas program dalam meningkatkan pemahaman terkait infertilitas. Selain itu, kegiatan ini berhasil menyebarkan informasi akurat dan memerangi mitos yang beredar di komunitas, sehingga meningkatkan kesadaran dan mengurangi stigma terhadap individu dengan infertilitas. Kesimpulannya, program ini efektif dalam meningkatkan dukungan sosial dan kapasitas tenaga medis untuk memberikan perawatan holistik yang lebih baik bagi pasien infertilitas, serta berkontribusi pada pengurangan dampak psikologis dan sosial yang dialami pasien.
Unraveling Of Urinary Disorders to Adenomyosis and Dysmenorrhea darto, darto; Anggraeni, Asih; Ngudi Insan Ksyatria, Yudhistira; Alifa, Rosita; Farras Wahdan, Arib; Retno Budihastuti, Uki; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; Angelia Ratnasari, Affi
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 1 January 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i1.2203

Abstract

Objective : This study aims to explore the relationship between micturition disorders and adenomyosis and dysmenorrhea and provide insight into the factors associated with the severity of LUTS symptoms in these conditions. Methods : This study was a descriptive qualitative study. We retrospectively collected medical record data from the Obstetrics Gynecology Outpatient Ward of Dr. Moewardi Surakarta General Hospital in the period January 2021 to May 2023. The results of this study analyzed using Pearson correlation analysis if normally distributed and using Mann-Whitney if not normally distributed, thus, statistically analyzed. Results: There is a significant relationship between adenomyosis and dysmenorrhea on urinary disorders (p value of 0.016) where urinary disorders are found to be more severe in adenomyosis patients with dysmenorrhea. Conclusion : Lower urinary tract symptoms are common in symptomatic adenomyosis patients and greatly affect the patient's quality of life. Dysmenorrhea can be a potential risk factor that increases the occurrence of moderate to severe LUTS. Keywords: adenomyosis; dysmenorrhea; urinary disturbance.
Hyaluronic Acid for Sperm Selection in Patients Undergoing IVF with Teratozoospermia : a Bibliographic Analysis Zacky Arda, Mohammad; Melinawati, Eriana; Pertiwi, Kartika
GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh Vol. 4 No. 4 (2025): GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh - Agustus 20
Publisher : Program Studi Kedokteran Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/jkkmm.v4i4.23902

Abstract

Sperm selection technique and Assisted Reproductive Technology (ART) often overlook patients with teratozoospermia, who are more likely to have Deoxyribonucleic Acid (DNA) fragmentation in their sperm, leading to reduced fertilization rates, poor embryo quality, and lower implantation rates during In Vitro Fertilization (IVF). Hyaluronic Acid (HA) binding sperm offers enhanced outcome in ART. This study aimed to obtain information from global scientific research related to HA and sperm selection during In Vitro Fertlization (IVF) procedure by identifying key research trends, influential studies, and emerging themes through bibliometric analysis. The Scopus database was employed to search articles published with keywords “HA,” “teratozoospermia,” and “IVF.” VOSviewer was used to visually represent the bibliometric data, revealing trends in research related to HA for IVF procedure in patients with teratozoospermia. There were 150 articles identified, of which terms like “fragmentation”, “teratozoospermia”, and “sperm abnormalities” are the highlight emerging topics to understand male infertility. Through the years, newer methodologies and techniques in sperm analysis and fertility treatments research had evolved, while research in HA and IVF had increased significantly in many publications and institutions. In conclusion, this bibliometric mapping study has identified key themes and emerging trends, including the critical roles of sperm morphology, motility, and selection in IVF. The growing interest in the relationship between HA and sperm selection techniques highlights the need for ongoing research into HA's application in sperm selection, particularly regarding DNA fragmentation and its effects on fertilization and embryo quality to improve reproductive outcomes.
Edukasi Menopause Sehat bersama Ikatan Istri Dokter Indonesia (IIDI) Menuju Kehidupan Berkualitas Budihastuti, Uki Retno; Melinawati, Eriana; Laqif, Abdurahman; Anggraeni, Asih; Ratnasari, Affi Angelia
Jurnal Pengabdian Masyarakat: Darma Bakti Teuku Umar Vol 7, No 1 (2025): Januari-Juni
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/baktiku.v7i1.13032

Abstract

Menopause is a natural phase that every woman must experience, but it is often accompanied by various physical and emotional complaints that can interfere with daily life and reduce the quality of life. The lack of understanding and access to information makes most women unprepared to face this phase. The purpose of community service activities is to increase the knowledge and awareness of women aged 40 years or older about the concept of healthy menopause. The activity was carried out in a hybrid manner at the Auditorium of the Faculty of Medicine, Sebelas Maret University, involving obstetrics and gynecology specialists, health workers, and members of the IIDI Solo Branch. The implementation method includes counseling, interactive discussions, and evaluation through a pretest and a posttest. The results of the activity showed an increase in the average knowledge score of participants from 82.43 to 85.59, accompanied by an increase in awareness of the importance of early detection and handling of menopausal complaints. These findings confirm that sustainable education is an effective strategy to improve the quality of life of women in the lead-up to old age, in line with the goals of SDG 3, which emphasizes the importance of ensuring healthy lives and well-being for all ages.
Peningkatan Kesadaran dan Deteksi Dini Kanker Serviks dan Kanker Payudara melalui Edukasi dan Skrining bagi Tenaga Kesehatan dan Masyarakat Budihastuti, Uki Retno; Melinawati, Eriana; Priyanto, Heru; Ratnasari, Affi Angelia; Susilawati, Tri Nugraha; Prastyoningsih, Aris; Septiana, Yesika Cahya; Mufidah, Amatullah
Jurnal Abdidas Vol. 6 No. 4 (2025): Agustus 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v6i4.1171

Abstract

Kanker serviks dan kanker payudara merupakan dua jenis kanker yang paling umum menyerang wanita di seluruh dunia. Kanker serviks disebabkan oleh infeksi human papillomavirus (HPV), sedangkan kanker payudara disebabkan oleh pertumbuhan sel abnormal pada jaringan payudara. Deteksi dini dan pengobatan yang tepat dapat meningkatkan kemungkinan kesembuhan dan mengurangi angka kematian. Oleh karena itu, edukasi dan deteksi dini kanker serviks dan kanker payudara sangat penting untuk meningkatkan kesadaran dan kesehatan masyarakat. Dalam pengabdian masyarakat ini, kami melakukan edukasi dan deteksi dini kanker serviks dan kanker payudara pada tenaga kesehatan dan masyarakat wanita yang berdomisili di area Solo Raya. Hasilnya menunjukkan bahwa edukasi dan deteksi dini dapat mengingatkan kembali kesadaran dan pengetahuan masyarakat tentang kanker serviks dan kanker payudara, serta meningkatkan kemungkinan deteksi dini dan pengobatan yang tepat.
Co-Authors ., Darto Abd. Rasyid Syamsuri Abdurahman Laqif Abdurahman Laqif Abida Zuhra Jatiningtyas Alfi Marita Tristiarti Alfi Marita Tristiarti Alfi Marita Tristiarti Alifa, Rosita Amira Masiah Syahvira Andreas Peter Sitorus Andreas Peter Sitorus Angelia Ratnasari, Affi Anggraeni, Asih Annang Giri Moelyo Asih Anggraeni Besar, Dwi Sakti Berlian Cahyono Hadi Darto Darto Darto - Darto - Darto Darto Dewi Kartika DJ Anwar Dwi Septiadi Badri Dyah Ratna Budiani Ediningtyas, Atifa Nadira Elita Rahmi Eric Edwin Yuliantara Fahsan, Fatmiyanti Farras Wahdan, Arib Hadi, Cahyono Hafiizha, Attahira Amalia Hanifah Karim Hapsari Nur Primastuti Hapsari Nur Primastuti Hermawan Udiyanto Heru Priyanto Heru Priyanto Ida Nurwati Jatiningtyas, Abida Zuhra Kartika Pertiwi Ksatriya, Yudhistya Ngudi Insan Laqif, Abdurahman Laqif, Abdurrahman Lukman Aryoseto Lukman Aryoseto Lunardhi Susanto Marbun, Yohan Pamuji Mashuri, Yusuf Ari Metanolia Sukmawati Mufidah, Amatullah Mulyoto Pangestu Ngudi Insan Ksyatria, Yudhistira Nutria Widya Purna Anggraini Nuur, Aliffudin Octavia, Dhamayanti Eka Prastyoningsih, Aris Prisasanti, Dympna Prameilita Raden Rara Pandhan Budi Larasati Rakano Kautsar Dwiyana Rantasari, Affi Angelia Ratnasari, Affi Angelia Regita, Immanuela Maria Saputra, Ricky Bernadi Sari, Arum Dessy Rahma Septiana, Yesika Cahya Sri Sulistyowati Sri Sulistyowati Supriyadi Hari Respati Supriyadi Hari Respati Tanti Arianti Teguh Prakosa, Teguh Tri Nugraha Susilawati Uki Retno Budihastuti Vicky Eko N.H Vicky Eko N.H Wasyanto, Trisulo Wesliaprilius, Todung Antony Wijayanti, Agung Sari WISNU PRABOWO Yulyanti, Yulyanti Zacky Arda, Mohammad