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All Journal Jurnal Biosains Pascasarjana Jurnal Penelitian Kesehatan Suara Forikes Jurnal Kesehatan Prima Indonesian Journal of Global Health research Medicra (Journal of Medical Laboratory Science/Technology) Anakes: Jurnal Ilmiah Analis Kesehatan JURNAL BIOSHELL Jurnal Pengabdian Masyarakat (ABDIRA) Jurnal EduHealth Jurnal Kesehatan Kolaborasi Jurnal Pengabdian Masyarakat Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Jurnal Pengabdian Masyarakat Waradin Jurnal Kesehatan Amanah Jurnal Pengabdian kepada Masyarakat Innovative: Journal Of Social Science Research Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Faedah: Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia Jurnal Pengabdian Masyarakat Kesehatan Terkini
Anas Fadli Wijaya
Universitas Dr. Soebandi
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Pemeriksaan Kesehatan Dan Edukasi Kesehatan Masyarakat Desa Kamal Dalam Upaya Mengontrol Kadar Gula Darah Aggustin, Ayu Tri; Wijaya, Anas Fadli; Muflihah, Ahdiah Imroatul; Hidayati, Sholihatil
PRAXIS: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 3 (2024): PRAXIS
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47776/praxis.v2i3.943

Abstract

This community service activity is a form of effort to support the government program "Healthy Communities that are Independent and Just. The target subjects for partners in this community service activity are the people in Kamal Village, Arjasa District, and Jember Regency. Preliminary studies have been carried out and show that the incidence rate in the village is very high. Thus, health checks and health promotion in an effort to control blood sugar levels through the use of natural germplasm are very necessary. The health checks that will be carried out include random blood sugar checks (GDS). The education provided can include understanding the causes, signs and symptoms, risk factors, and types of healthy nutrition to prevent and control complications of diabetes mellitus. Early screening can be done by carrying out laboratory examinations in the community. After the examination, it was discovered that some people experienced hyperglycemia and some experienced hypoglycemia. Through this activity, the public can understand the material presented and can find out their health status so that early prevention can be carried out.
The Relationship between HbA1c and Glucosuria in Diabetes Mellitus (DM) Patients: Hubungan HbA1c dengan glukosuria Pada Penderita Diabetes Mellitus (DM) Nurjanah, Mutia Hariani; Wijaya, Anas Fadli; Meri, Meri; Tilarso, Dara Pranidya; Siswidiani, Maya Diva
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1727

Abstract

Diabetes mellitus is a condition of abnormalities in blood glucose metabolism that can cause various macroangiopathy complications such as disorders of the peripheral blood vessels, heart blood vessels, cerebral blood vessels as well as microangipathic complications such as diabetic retinopathy disorders, nephropathy and neuropathy. HbA1c describes the level of sugar in the blood for the last 3 months. Glucose is not found in normal urine because it is reabsorbed back into the blood vessels by renal filtration. The aim of this study was to determine the relationship between HbA1c levels and glucosuria in people with diabetes mellitus. The design of this study is a cross-sectional approach to DM patients. The sampling technique used was purposive sampling. Data analysis was carried out by means of Spearman's rank correlation test. Results Correlation analysis showed that there was a significant relationship between HbA1c levels and glucosuria in DM patients p-value 0.005 with a coefficient value of 0.597. The conclusion from this study is that there is a significant relationship with a strong correlation strength and a positive correlation direction for DM sufferers.
Skrining Status Kadar Gula Darah dan Kolestrol Total Sebagai Upaya Untuk Mencegah Penyakit Meta-Inflamasi Anas Fadli Wijaya; Rian Anggia Destiawan; Ahdiah Imroatul Muflihah
Faedah : Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia Vol. 1 No. 1 (2023): Februari : Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia
Publisher : FKIP, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/faedah.v1i1.41

Abstract

Indonesia merupakan salah satu negara dengan tingkat kematian tertinggi akibat penyakit tidak menular yang disebabkan oleh penyakit terkait metainflamasi terutama untuk penyakit diabetes melitus, hipertensi dan jantung koroner. Kontributor utama terjadinya penyakit tidak menular terkait metainflamasi adalah pola hidup yang tidak sehat seperti kebiasaan pola makan dengan konsumsi lemak dan glukosa berlebih, aktivitas fisik yang kurang, stres, dan pencemaran lingkungan. Masyarakat dengan resiko tinggi tentunya memerlukan skrining dini dan pengetahuan yang memadai tentang penyakit terkait metainflamasi. Skrining dan peningkatan pengetahuan tersebut dapat dilakukan oleh tenaga laboratorium dengan pemeriksaan laboratorium dan penyuluhan kesehatan. Tujuan pengabdian masayarakat ini adalah untuk skrining dini serta peningkatan pengetahuan untuk mencegah penyakit terkait meta-inflamasi. Metode pelaksanaan pengabdian masyarakat ini terdiri dari tiga tahap yaitu tahap persiapan, pelaksaanaan, dan evaluasi. Pada tahap pelaksanaan dilakukan pemeriksaan kadar gula darah sewaktu dan kolestrol total serta edukasi terkait penyakit meta-inflamasi. Hasil pengabdian masyarakat, masyarakat telah memperoleh status kesehatan melalui pemeriksaan laboratorium serta pengetahuan yang baik tentang penyakit meta-inflamasi.
Edukasi Kesehatan Pengaruh Kualitas Tidur Terhadap Kadar Hb dan Imunitas Tubuh Pada Remaja Anas Fadli Wijaya; Rian Anggia Destiawan; Pratikah Verdianti
Jurnal Pengabdian Masyarakat Waradin Vol. 1 No. 3 (2021): September : Jurnal Pengabdian Masyarakat Waradin
Publisher : Sekolah Tinggi Ilmu Ekonomi Pariwisata Indonesia Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/wrd.v1i3.299

Abstract

Sleep quality is a state lived by an individual to produce freshness and fitness after waking up. If a person's sleep quality is poor it will cause a decrease in the body's immune system and Hb levels which causes the individual to feel easily tired, sleepy and susceptible to disease. Adolescents are identified as a population at high risk of experiencing sleep problems which disrupt sleep quality. Accumulated work and lifestyle are one of the factors causing poor sleep patterns in adolescents which makes it easier for them to experience sleep disturbances. Adolescents with high risk certainly need adequate knowledge regarding the importance of maintaining quality sleep related to the body's immune system and Hb levels. Increased knowledge and examination can be carried out by laboratory personnel with health counseling and laboratory tests. The purpose of this community service is to increase the knowledge of adolescents to maintain good quality sleep so that Hb levels and body immunity are maintained. This community service implementation method consists of three stages, namely the preparation, implementation, and evaluation stages. At the implementation stage, an examination of Hb levels and counting the number of types of leukocytes was carried out as well as education related to the effect of sleep quality on Hb levels and the body's immune system. As a result of community service, adolescents have obtained health status through laboratory tests and good knowledge about the effect of sleep quality on Hb levels and body immunity.
Uji Potensi Senyawa Bioaktif Ekstrak Antosianin Jagung Ungu sebagai Inhibitor Cyclin-Dependent Protein Kinase 6 (CDK6) Ayu Tri Agustin; Anas Fadli Wijaya
Jurnal Kesehatan Amanah Vol. 7 No. 2 (2023): Oktober: Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v7i2.758

Abstract

Cancer is characterized by uncontrolled cell proliferation. The upregulation and activation of the Cyclin-Dependent Protein Kinase 6 (CDK6) signaling pathway can induce unregulated breast cancer cell proliferation. Therefore, CDK6 inhibition continues to be developed as a potential target for drug design and development to treat breast cancer. This study aims to predict the biofunction of anthocyanin compounds from purple corn extract as inhibitors of Cyclin-Dependent Protein Kinase 6 (CDK6) using an in silico approach. The research methods included data mining, ligand and receptor preparation, molecular docking, docking visualization, and data analysis. Our results indicate that six compounds from purple corn extract (cyanidin, cyanidin 3-glucoside, pelargonidin-3-glucoside, pelargonidin, peonidin, and peonidin-3-glucoside) can bind to CDK6 at the C-terminal and N-terminal domains. The binding pattern suggests that cyanidin, cyanidin 3-glucoside, pelargonidin-3-glucoside, pelargonidin, peonidin, and peonidin-3-glucoside interact with CDK6 residues in the same manner as Palbociclib (control). This finding indicates that compounds from purple corn have the potential to act as competitive CDK6 inhibitors. Peonidin-3-glucoside exhibited the lowest binding energy of -282.5 kcal/mol, approaching that of Palbociclib (-329.4 kcal/mol).
Uji Potensi Senyawa Bioaktif Ekstrak Antosianin Jagung Ungu sebagai Inhibitor Cyclin-Dependent Protein Kinase 6 (CDK6) Ayu Tri Agustin; Anas Fadli Wijaya
Jurnal Kesehatan Amanah Vol. 8 No. 2 (2024): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v8i2.761

Abstract

Cancer is characterized by uncontrolled cell proliferation. The upregulation and activation of the Cyclin-Dependent Protein Kinase 6 (CDK6) signaling pathway can induce unregulated breast cancer cell proliferation. Therefore, CDK6 inhibition continues to be developed as a potential target for drug design and development to treat breast cancer. This study aims to predict the biofunction of anthocyanin compounds from purple corn extract as inhibitors of Cyclin-Dependent Protein Kinase 6 (CDK6) using an in silico approach. The research methods included data mining, ligand and receptor preparation, molecular docking, docking visualization, and data analysis. Our results indicate that six compounds from purple corn extract (cyanidin, cyanidin 3-glucoside, pelargonidin-3-glucoside, pelargonidin, peonidin, and peonidin-3-glucoside) can bind to CDK6 at the C-terminal and N-terminal domains. The binding pattern suggests that cyanidin, cyanidin 3-glucoside, pelargonidin-3-glucoside, pelargonidin, peonidin, and peonidin-3-glucoside interact with CDK6 residues in the same manner as Palbociclib (control). This finding indicates that compounds from purple corn have the potential to act as competitive CDK6 inhibitors. Peonidin-3-glucoside exhibited the lowest binding energy of -282.5 kcal/mol, approaching that of Palbociclib (-329.4 kcal/mol).
Aktivitas Madu Trigona (Trigona sp) Terhadap Gambaran Infiltrasi Sel Radang di Dermis pada Tikus (Rattus novergicus) dengan Model Luka Bakar Rian Anggia Destiawan; Anas Fadli Wijaya; Ahdiah Imroatul Muflihah
Jurnal Penelitian Kesehatan SUARA FORIKES 2022
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf13nk342

Abstract

Burns are caused by chemicals, hot liquids and fires. Burns cause skin tissue necrosis, thus removing cell components including heat shock protein (HSP), monosodium urate, high-mobility group box protein 1 (HMGB1), extracellular ATP, and mitochondrial DNA including nucleic acids which are referred to as Damage Associated Molecules. Patterns (DAMPS). DAMPS cause increased infiltration of inflammatory cells into tissues. The purpose of this study was to determine the activity of trigona honey (Trigona sp) based on inflammatory cell infiltration in rats (Rattus novergicus) with the burn model. The research method was to group into 5 groups, including KN (negative control), K-1 (burns + placebo), K-2 (burns + silver sulfadiazine), K-3 (burns + 50% trigona honey), and K-4 (burns + 100% trigona honey), then stained with Hematoxylin Eosin (HE) to see the presence of inflammatory cell infiltration. Statistical analysis using the Kruskal Wallis and Mann-Whitney tests. Microscopically (inflammatory cell infiltration score) it showed that the KN group had a score of 0, group K-1 had a score of 4, group K-2 had a score of 2, groups K-3 and K-4 had a score of 4 and 2. statistically, there was no difference between groups. The conclusion of this study is that 100% trigona honey can reduce inflammatory cell infiltration in the dermis area of skin that has experienced burns.Keywords: burns, trigona honey, silver sulvadiazine ABSTRAK Luka bakar disebabkan oleh bahan kimia, cairan panas, dan kebakaran. Luka bakar menyebabkan nekrosis jaringan kulit, sehingga mengeluarkan komponen-komponen sel diantaranya heat shock protein (HSP), monosodium urate, high-mobility group box protein 1 (HMGB1), ekstraseluler ATP, dan DNA mitokondria termasuk asam nukleat yang disebut sebagai Damage Associated Molecullar Pattern (DAMPS). DAMPS menyebabkan peningkatan infiltrasi sel radang ke dalam jaringan. Tujuan penelitian ini adalah mengetahui aktivitas madu trigona (Trigona sp) berdasarkan infiltrasi sel radang pada tikus (Rattus novergicus) dengan model luka bakar. Metode penelitian ini adalah melakukan pengelompokan menjadi 5 kelompok, di antaranya KN (kontrol negatif), K-1 (Luka bakar + placebo), K-2 (Luka bakar + silver sulfadiazine), K-3 (Luka bakar + madu trigona 50%), dan K-4 (Luka bakar + madu trigona 100%), kemudian dilakukan pewarnaan Hematoksilin Eosin (HE) untuk melihat adanya infiltrasi sel radang. Analisa statistik menggunakan uji Kruskal Wallis dan Mann-Whitney. Secara mikroskopis (skor infiltrasi sel radang) menunjukkan bahwa pada kelompok KN nilai skoringnya 0, kelompok K-1 nilai skoringnya 4, kelompok K-2 nilai skoringnya 2, pada kelompok K-3 dan K-4 nilai skoringnya 4 dan 2. Namun secara statistik, tidak terjadi perbedaan antar kelompok. Kesimpulan dari penelitian ini adalah bahwa madu trigona 100% dapat menurunkan infiltrasi sel radang di daerah dermis pada kulit yang mengalami luka bakar.Kata kunci: luka bakar, madu trigona, silver sulvadiazine
Implementasi Program Edukasi Cuci Tangan Berbasis Permainan untuk Meningkatkan Perilaku Pencegahan Demam Tifoid pada Anak Sekolah SDN 1 Dono Tulungagung Nurjanah, Mutia Hariani; Fuzianingsih, Eka Novia; Kumalasari, Nurul Chamidah; Sulastri, Sulastri; Martha, Rahma Diyan; Wijaya, Anas Fadli; Widayanti, Sindi Dwi
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 5, No 3 (2025): Abdira, Juli
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v5i3.751

Abstract

Typhoid fever remains a public health issue in Indonesia, especially among elementary school children who are vulnerable due to poor hygiene habits, particularly not washing hands. Traditional education methods often fail to change children's behavior, so more engaging and interactive approaches are needed. This activity aimed to improve handwashing behavior through educational games. A quasi-experimental method with a pretest-posttest control group design was used. The intervention involved 40 students from SDN 1 Dono, Tulungagung, using games like hygiene-themed snakes and ladders and handwashing step cards. Evaluation was conducted through pretest and posttest assessments and group discussions with teachers. Results showed a significant improvement in the intervention group from 70% (poor category) to 83% (good category), with a p-value of 0.000. In contrast, the control group showed no significant change (p = 0.213). Educational games proved effective in improving students’ handwashing behavior and can be a preventive strategy against typhoid fever in schools.
Sosialisasi Peningkatan Gerakan 1 Rumah 1 Jumatik Untuk Pengendalian Demam Berdarah Dengue Mufidah, Hartalina; Agustin, Ayu Tri; Wijaya, Anas Fadli; Muflihah, Ahdiah Imroatul
Kolaborasi: Jurnal Pengabdian Masyarakat Vol 5 No 3 (2025): Kolaborasi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/kolaborasi.v5i3.511

Abstract

Introduction: Dengue Hemorrhagic Fever remains a significant health problem in Jember Regency. Jember Regency is among the top three districts with the highest dengue cases in East Java, reporting 781 cases, alongside Malang Regency was 1,224 cases and Ngawi Regency was 673 cases. It situation may be attributed to the lack of public awareness about maintaining a mosquito-free environment and the suboptimal implementation of the "1 House 1 Mosquito Monitor" (G1R1J). Kamal Village is one of the areas with environmental conditions conducive to mosquito breeding and the spread of Dengue Hemorrhagic Fever. Socializing the "1 House 1 Mosquito Monitor" is crucial to increasing public knowledge about the causes of Dengue Hemorrhagic Fever and the importance of Jumantik's role. Objective: The purpose of this service was promote the "1 House 1 Mosquito Monitor" and conduct screening IgM/IgG in Duplang Hamlet, Kamal Village, Arjasa District, Jember Regency Method: This public service was conducted by by socializing the definition of dengue disease, symptoms, prevention and the 1 House 1 Mosquito Monitor using leaflet. Then it was followed by IgG and IgM assay using Rapid test. The number of residents who participated was 16 people. Result: Socialization of One House One Mosquito Monitor were 3M Plus Dengue Prevention (Drain, Cover, Bury), control the mosquito breeding, and Larvacide applications. The IgG and IgM test results showed negative Conclusion: This community service was the successful socialization of the "1 House 1 Mosquito Monitor". None of them had been exposed to the dengue virus.
Peningkatan Pengetahuan Masyarakat Tentang Golongan Darah Melalui Sosialisasi dan Pemeriksaan di Dusun Duplang Jember: Enhancing Community Knowledge on Blood Types Through Socialization and Screening In Dusun Duplang Jember Wijaya, Anas Fadli; Agustin, Ayu Tri; Mufidah, Hartalina; Purwanto, Sigit; Humairoh, Riska Tsamarah; Elnaja, Dinar Anisa; Hayati, Farhatul; Purwanti, Ananda Kamila Nurcahya
Jurnal Pengabdian Kepada Masyarakat: Kesehatan Vol. 5 No. 2 (2025): Juli
Publisher : Sekolah Tinggi Ilmu Kesehatan Notokusumo Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstrak: Golongan darah A,B,O, dan AB dan rhesus merupakan salah satu pewarisan genetik. Pengetahuan tentang jenis golongan darah yang dimiliki sangat krusial untuk mengetahui kompatibilitas golongan darah. Hal ini berperan penting ketika suatu individu mengalami kecelakaan dan terkena penyakit tertentu sehingga membutuhkan transfusi darah dalam waktu singkat. Pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan tentang pentingnya mengetahui golongan darah melalui sosialisasi dan pemeriksaan golongan darah A,B,O, dan AB. Pengabdian kepada Masyarakat ini dilaksanakan di Dusun Duplang, Desa Kamal, Kecamatan Arjasa, Kabupaten Jember. Metode yang digunakan meliputi penyuluhan menggunakan leaflet dan poster dan pre-test dan post-test. Kemudian dilanjutkan dengan pemeriksaan golongan darah A,B,O, dan AB menggunakan slide test dari warga masyarakat yang hadir Hasil menunjukkan bahwa mayoritas responden memiliki golongan darah B dan O. Sosialisasi terbukti efektif dalam meningkatkan kesadaran masyarakat sebesar 75,9% tentang pentingnya pengetahuan tentang golongan darah untuk kesiapan dalam keadaan darurat.   Abstract: Blood types A, B, O, and AB and rhesus are one of the genetic inheritances. Knowledge of the type of blood type was crucial to determine blood type compatibility. It plays an important role when an individual has an accident and is affected by certain diseases that require blood transfusions in a short time. The purpose of this service was increase knowledge about the importance of knowing blood types through socialization and examination of blood types A, B, O, and AB. This public service was conducted at Duplang Hamlet, Kamal Village, Arjasa District, Jember Regency with the participation of 16 respondents. This public service was conducted by socializing using leaflets and posters and pre-test and post-test. Then it was followed by blood type assay A, B, O, and AB using slide tests from public respondence who attended. The results showed that the majority of respondents had blood types B and O. Socialization proved effective in increasing public awareness in 75,9% of the importance of knowledge about blood types for emergency preparedness.
Co-Authors Ade Sucipto Aggustin, Ayu Tri Agustin, Ayu Tri AHDIAH IMROATUL MUFLIHAH Alisa Alfiya Makki Arif Santoso Azizah, Laila Camelia Nur Elnaja, Dinar Anisa Fuzianingsih, Eka Novia Hanifiyah, Fitroh Hayati, Farhatul Hidayati, Larantika Hidayati, Sholihatil Holifah, Siti Nur Humairoh, Riska Tsamarah Ikhsan, Ahmad Mufti Kamaliyah, Indy Kumalasari, Nurul Chamidah Laila Camelia Laila Camelia Nur Azizah Laksono, Eko Budi Lenny Yulia Widia Sari Leny Yulia Widia M Syaifuddin M. Elyas Arif Budiman Makki, Alisa Alfiya Maruni Wiwin Diarti Meri, Meri Mufidah, Hartalina Mutia Hariani Nurjanah Mutiurrohman, Achmad Ni Ketut Yuliana Sari Nosa Ika Cahyariza Nosa Ika Cahyariza Nurjanah, Mutia Hariani Pratikah Verdianti Purwanti, Ananda Kamila Nurcahya Putri, Diva Amalia Queen Nurul Sufi Rahma Diyan Martha Rahmawati, Ayu Sintya Citra Rahmawati, Septyana Eka RIAN ANGGIA DESTIAWAN Rian Anggia Destiawan Romaidha, Iqlila Rossa, Handita Emilia Safitri, Yunita Diyah Sholihatil Hidayati Sigit Purwanto Siswidiani, Maya Diva Siti Maimunah Sofia Soleha, Nurmaidatus sufi, Queen Nurul Sulastri Sulastri Tilarso, Dara Pranidya Urip Urip Wafa, Muhammad Ali Widayanti, Sindi Dwi Widia, Leny Yulia Yunan Jiwintarum