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Formulasi Emulgel Gamma Oryzanol dengan Menggunakan Carbopol sebagai Gelling Agent Dahlizar, Sabrina; Nurkhasanah, Nurkhasanah; Betha, Ofa Suzanti; Anggraeni, Yuni
JSFK (Jurnal Sains Farmasi & Klinis) Vol 9 No 2 (2022): J Sains Farm Klin 9(2), Agustus 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.2.129-137.2022

Abstract

Gamma-oryzanol merupakan senyawa antioksidan alami yang diperoleh dari minyak dedak padi atau yang lebih dikenal dengan rice bran oil (RBO). Gamma-oryzanol diketahui dapat melindungi kulit dari radiasi ultraviolet dan meningkatkan kelembaban kulit, sehingga dapat dimanfaatkan sebagai antikerut dan pelembab kulit di bidang kosmetik. Terdapat dua komponen penting yang menentukan sifat fisik emulgel, yaitu emulgator dan gelling agent. Penelitian ini bertujuan untuk membandingkan pengaruh variasi konsentrasi polimer karbopol 940 sebagai gelling agent terhadap sifat fisik emulgel gamma-oryzanol. Konsentrasi karbopol 940 yang digunakan dalam formulasi adalah 0,5% (pada F1), 0,75% (pada F2) dan 1 % (pada F3). Evaluasi sifat dan stabilitas fisik sediaan emulgel dilakukan terhadap beberapa parameter uji, yaitu pengamatan organoleptis, pengukuran diameter globul rata-rata, penentuan pH, penentuan sifat alir dan kekentalan, uji daya sebar dan uji sentrifugasi. Evaluasi stabilitas fisik sediaan emulgel dilakukan dengan menggunakan metode penyimpanan pada suhu 4oC, 26±2oC dan 40oC, uji cycling test dan uji sentrifugasi. Hasil penelitian menunjukkan bahwa variasi konsentrasi karbopol 940 berpengaruh terhadap sifat dan stabilitas fisik sediaan. Peningkatan konsentrasi karbopol 940 menyebabkan terjadinya peningkatan viskositas emulgel dan ukuran diameter globul rata-rata, serta  penurunan daya sebar. Uji stabilitas fisik menunjukkan ketiga formula sediaan emulgel gamma-oryzanol mengalami perubahan nilai parameter uji yang tidak bermakna pada sifat organoleptis. Berdasarkan hasil uji sentrifugasi, emulgel yang mengandung Carbopol 0,75% (F2) memiliki stabilitas fisik terbaik. 
Comparative analysis of macronutrient, vitamin, and mineral intake between stunted and non-stunted children in cirebon Pandanwangi, Siti; Akrom, Akrom; Nurkhasanah, Nurkhasanah; Zuniarto, Ahmad Azrul
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 2 (2025): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.2.162-169

Abstract

Background: The food consumed by children greatly affects how they will live in the future. The amount of nutrition that enters a child's body affects their health and intelligence. Macronutrients, vitamins and minerals are vital components in the body for the processes of growth and development, endurance, and other important functions. Low nutritional intake in children will cause them to experience growth failure, resulting in stunting.Objectives: This study was to compare the intake of macronutrients (protein, fat, and carbohydrate), vitamins (A, E, B1, B2, B6, C, folate), and minerals (sodium, potassium, magnesium, calcium, phosphorus, iron, and zinc) between stunted and non-stunted childrenMaterials and Methods: This study used a cross-sectional design. The population of the study was toddlers living in the Tegalwangi area, a sample of 100 children, ages 2 to 5, who were willing to sign a consent form as research subjects was split into 50 stunting and 50 non-stunting children. The time for the study began in January-May 2023. Data was collected using the 3x24 hour nutritional recall questionnaire method, followed by converting nutritional intake through the Nutrisurvey softwareResults: Nutritional intake for stunted children, shows that there are 12 intake criteria below the nutritional adequacy rate, while 5 intake criteria meet the standard. While for children who are not stunted, 12 criteria meet and 5 criteria do not meet the nutritional adequacy standard.Conclusion: Analysis of differences in the intake of the two groups found that there were no significant differences in the intake of macronutrients (carbohydrates), vitamins (E, B2) and minerals (sodium, potassium, calcium and phosphorum) with p>0.05, and significant differences in the intake of macronutrients (protein, fat). vitamins (A, B1, B6, C, folate), and minerals (magnesium, iron, zinc) with p<0.05. 
PENDAMPINGAN SKRINING KESEHATAN DAN EDUKASI PEMANFAATAN TANAMAN OBAT DALAM PENCEGAHAN PENYAKIT DEGENERATIF PADA MASYARAKAT KAMPUNG BATU 14, PUCHONG, SELANGOR MALAYSIA Saputri, Ginanjar Zukhruf; Nurkhasanah, Nurkhasanah; Jailani, Muhammad Taufiq Bin Mohd; Aprilia, Kartini; Nada, Rafa; Ahmad, Nur; Ahmad, Aunillah; Adiba, Thoriq
Jurnal Abdi Insani Vol 12 No 6 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i6.2622

Abstract

Prevalensi penyakit tidak menular (PTM) masih menjadi permasalahan kesehatan baik di Indonesia dan Malaysia, khususnya di Kampung Batu 14, Puchong, Selangor, Malaysia. Beberapa permasalahan diantaranya (1) tingginya penyakit degeneratif (diabetes melitus dan kolesterol); (2) pola penggunaan obat di masyarakat dengan kombinasi pengobatan modern dan tradisional; (3) terbatasnya pemanfaatan tanaman obat secara mandiri di masyarakat. Berdasarkan hal tersebut, pengabdian kepada masyarakat Internasional diajukan bertujuan untuk melakukan “Pendampingan skrining kesehatan dan edukasi pemanfaatan tanaman obat dalam pencegahan penyakit degeneratif”. Kegiatan PKM Internasional bermitra dengan PCI IMM Malaysia dengan sasaran Masyarakat Batu 14 Puchong, Selangor, Malaysia. Metode pelaksanaan melalui penyampaian materi secara langsung (penyuluhan/edukasi), skrining kadar gula darah dan kolesterol, serta simulasi praktek pengolahan tanaman obat. Kegiatan PKM dilakukan dalam dua sesi, sesi ke-1 pada volunteer kesehatan (anggota PCI IMM Malaysia berjumlah 11 orang), dan sesi ke-2 pada mitra sasaran warga Kampung Batu 14, Puchong, Selangor, Malaysia (berjumlah 20 orang). Pengukuran tingkat pengetahuan peserta dilakukan melalui kuesioner pretes dan postest. Hasil skrining kesehatan menunjukkan mayoritas peserta memiliki rerata tekanan darah=128.53/83,03 mmHg; kadar gula darah=6,31 mmol/L; kadar kolesterol=3,79 mmol/L. Keseluruhan rerata hasil skrining baik pada kedua kelompok menunjukkan pada rentang normal. Tingkat pengetahuan warga Kampung Batu 14 meningkat setelah mendapatkan edukasi kesehatan, yaitu 60% kategori pengetahuan tinggi, dan 40% kategori pengetahuan sedang. Kesimpulan dari kegiatan PKM menunjukkan bahwa Pendampingan Skirining dan Edukasi Pemanfaatan Tanaman Obat mampu meningkatkan pengetahuan pencegahan penyakit degeneratif baik pada volunteer kesehatan maupun warga Kampung Batu 14, Puchong Selangor, Malaysia.
Antioxidant Effects of Temulawak and Black Cumin Honey in Stunted Children: A Study in Cirebon Siti Pandawangi TW; Akrom, Akrom; Nurkhasanah, Nurkhasanah; Ahmad Azrul Zuniarto
Journal of Public Health and Pharmacy Vol. 5 No. 2 (2025): July 2025
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v5i2.5950

Abstract

Introduction: The imbalance between the production of free radicals and the antioxidant defense system in the body will cause the body to experience oxidative stress. This can be caused by chronic malnutrition. In children, this condition causes growth and development failure called stunting. Honey, temulawak and black cumin are herbs with high antioxidant content, formulated in one preparation to test its effectiveness. The purpose of the study was to determine specific descriptions experienced by stunted children and to test the antioxidant effectiveness of preparation temulawak-black cumin honey. Methods: The research method used was quasi-experimental, pre-post design, the research time starts from January-May 2023. The population of Stunting children in the Tegalwangi locus area, Cirebon Regency, the selected samples or subjects are children aged 24-60 months who meet the inclusion criteria. The subjects were divided into 2 groups, namely the treatment group that received the test preparation for 4 months and the control group without the provision of the test preparation. Blood sampling was carried out simultaneously or simultaneously at the village hall with the help of trained analysts. The antioxidant parameters superoxide dismutase, catalase, glutathione peroxidase and free radical parameters Nitric oxide and malondialdehyde. The data obtained will be analysed using an independent t-test. Results: The results of the study on 50 stunted children showed low levels of Superoxide Dismutase, Catalase, Glutathione peroxidase, and free radical parameters Nitric oxide and Malondialdehyde were obtained high. This means that stunted children experience oxidative stress. There was significant antioxidant effectiveness with increased levels of SOD and Catalase in the treatment group (P<0.05), a decrease in NO and MDA in the treatment group (P<0.05) compared to the control group. Conclusion: Temulawak-black cumin honey preparation has activity to reduce oxidative stress in stunted children in Cirebon.
Analisis Implikasi Konsep Sistem Among Dan Trikon Pendidikan Ki Hajar Dewantara di Madrasah Ibtidaiyah Dianingsig, Dianingsih; Nurkhasanah, Nurkhasanah; Anisah, Retnani; Harni, Harni; Soedjono, Soedjono
Jurnal Inovatif Manajemen Pendidikan Islam Vol. 3 No. 2 (2024): July
Publisher : UII Darullughah Waddawah Pasuruan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38073/jimpi.v3i2.1661

Abstract

This research is motivated by the inconsistency between the curriculum used, namely the independent curriculum, and the practice in the field that is not student-centered. In addition, there is a lack of filters in responding to foreign cultures that enter through technology. The purpose of this study is to analyze the implications of the application of the concept of system among KHD Education in the learning process and the implications of the application of the concept of the theory of KHD Education in the use of technology in learning at MIN 1 Rembang. The research method used is a qualitative descriptive method. In this study, the subjects are teachers at MIN 1 Rembang. Data collection techniques were obtained from documentation, observation, and interviews. Data analysis techniques go through the stages of data collection, data reduction, data presentation, and conclusion. Based on the results of the study, it was obtained that the application of the concept of among system Ki Hajar Dewantara in MIN 1 Rembang was carried out based on the kinship and independence of students which helped students to learn and develop their abilities. Then the application of the concept of Trikon theory is carried out based on three principles, namely continuity, convergence, and concentricity.
Climate Change Disclosure in the Indonesian Banking Industry: a Case Study Of Jtrust Bank, Shinhan Bank, and Ok Bank (2020–2024) Nurkhasanah, Nurkhasanah; Meiden, Carmel
Asian Journal of Social and Humanities Vol. 3 No. 12 (2025): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v3i12.614

Abstract

Climate change has become a significant global issue and is increasingly gaining attention in the financial sector, including the banking industry. This study analyzes the level of climate change disclosure by three foreign banks in Indonesia JTrust Bank, Shinhan Bank, and OK Bank with a focus on the implementation of the Task Force on Climate-related Financial Disclosures (TCFD) framework, which covers four pillars: Governance, Strategy, Risk Management, and Metrics and Targets. Using a content analysis method of the Adequacy and Accuracy of Reporting indexes for the 2020–2024 period, both quantitative and qualitative assessments were conducted to evaluate the consistency and depth of disclosures. The results show that JTrust Bank has the highest level of disclosure, followed by Shinhan Bank and OK Bank. These differences are influenced by internal preparedness, strategic commitment to sustainability, and the regulatory policies of their home countries. This study emphasizes the importance of integrating climate issues into banks' governance and business strategies, and it is expected to provide both academic and practical contributions to encourage climate disclosure transparency in line with international standards
EFEK EKSTRAK ETANOL KELOPAK ROSELLA (Hibiscus sabdariffa L.) TERHADAP SEKRESI NITRIT OXIDA (NO) MAKROFAG PERITONEUM TIKUS YANGDIINDUKSI 7,12-dimethylbenz(α)antracene (DMBA) Nurkhasanah, Nurkhasanah; Zulkarmen, Lovrina Rahmi
Media Farmasi: Jurnal Ilmu Farmasi Vol. 11 No. 2: September 2014
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v11i2.1875

Abstract

Sistem imun merupakan sistem perlindungan tubuh terhadap penyakit. Senyawa DMBA dilaporkan memiliki efek imunosupresif. Tujuan penelitian ini untuk mengetahui efek ekstrak etanol kelopak rosella terhadap sekresi Nitrit Oxide makrofag tikus SD yang diinduksi DMBA. Tikus jantan galur SD sebanyak 25 ekor dibagi menjadi 5 kelompok, masing-masing kelompok terdiri dari 5 ekor tikus, kelompok I (normal) yang hanya diberi makan dan minum saja, kelompok II diberi DMBA 15 mg/tikus dan kelompok III, IV, V sebagai kelompok perlakuan yaitu diberi ekstrak etanol kelopak rosella dengan dosis 10 mg/kgBB, 50 mg/kgBB dan 100 mg/kgBB per oral. Setelah diberikan perlakuan, 5 ekor tikus pada masing-masing kelompok dibedah dan uji sekresi NO makrofag. Sekresi NO dilakukan dengan metode Griess assay. Data yang diperoleh dianalisis dengan uji Kolmogorof Smirnov, kemudian dilanjutkan dengan uji ANOVA dan uji post hoc LSD untuk melihat kelompok mana saja yang menunjukkan perbedaan yang bermakna. Dari penelitian yang dilakukan diperoleh hasil bahwa terjadi pada kelompok DMBA terjadi penurunan sekresi NO dibandingkan normal. Perlakuan ekstrak rosella meningkatkan sekresi NO setelah perlakuan DMBA. Dosis ekstrak etanol kelopak rosella yang paling efektif dalam meningkatkan sekresi NO makrofag yaitu pada dosis 50 mg/kgBB.   
Public perception of halal medicine certification Utami, Zhazha Zetira; Nurkhasanah, Nurkhasanah
Journal of Halal Science and Research Vol. 2 No. 2 (2021): September
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (724.185 KB) | DOI: 10.12928/jhsr.v2i2.3176

Abstract

The trend of the halal industry has increased, both in the world and in Indonesia. The development of halal industry trend has developed in all fields, one of which is halal certification of drugs. Drug products are now also a special concern in the halal product category because, in terms of treatment, society demands that the health products used must be of high quality and halal. The purpose of the study was to find out how the public's perception of halal drug certification and whether there was a relationship between the level of knowledge and the perception of drug halal certification. This type of research is an analytic observational research survey section with a cross-sectional approach. Obtained 102 respondents, then the data were analyzed using the SPSS application, both univariate and bivariate analysis. The results showed that the level of knowledge was moderate (63.7%), the level of perception was good (64.7%) and the level of behavior was good (64.7%). Knowledge has a linear relationship (sig value 0.168 > 0.05) significantly (f value 1.557 < 2.20) to respondents' perceptions of halal certification of drugs, and perceptions of drug halal certification also have a linear relationship (sig value 0.119 > 0, 05) significantly (f value 1.805 < 2.31) on the respondent's drug consumption behavior. Public perception of drug halal certification is good (64.7%) and the better the level of knowledge, the better the perception of drug halal certification (significantly linear).
PELATIHAN PENGOLAHAN DAGING KELAPA MENJADI (VIRGIN COCONUT OIL) SEBAGAI UPAYA EKONOMI KREATIF DESA LABUAN Nuranisa, Nuranisa; Nurkhasanah, Nurkhasanah; Amiruddin, Muhammad; Kurniawan, Arie; Hamzah Karim, Siti Aminah; Lengkong, Siti Nur Asyura; Tokay, Anwar
Jurnal Pengabdian Kompetitif Vol. 4 No. 2 (2025): Inovasi Teknologi dan Digital untuk Pemberdayaan UMKM dan Desa Mandiri
Publisher : Komunitas Manajemen Kompetitif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35446/pengabdiankompetif.v4i2.2463

Abstract

Penjualan hasil panen kelapa kepada tengkulak menyebabkan pemanfaatan buah kelapa yang tidak efesien dalam proses pengolahan menjadi produk, sehingga pengolahan buah kelapa menjadi produk masih kurang. Inovasi pembuatan Virgin Coconut Oil adalah salah satu bentuk pengolahan hasil pascapanen yang dapat dimanfaatkan sebagai produk Kesehatan yang dapat digunakan oleh Masyarakat. Program pengabdian ini bertujuan untuk meningkatkan pengetahuan dan keterampilan Masyarakat Desa Labuan dalam kegiatan pelatihan pembuatan VCO dari daging kelapa sebagai ekonomi kreatif masyarakat. Metode yang digunakan dalam kegiatan ini meliputi pelatihan kepada masyarakat dengan menyajikan materi dan praktek langsung dalam memanfaatkan sumber daya alam lokal sebagai produk olahan hasil panen. Evaluasi akan dilakukan dalam bentuk pre-test Untuk mengetahui pemahaman awal mereka tentang pengolahan hasil panen. Keberlanjutan program dilakukan dengan pengamatan hasil fermentasi Virgin Coconut Oil selam 3 sampai 5 hari. Hasil yang diharapkan dari kegiatan ini adalah meningkatnya pemahaman Masyarakat mengenai pengolahan buah kelapa dan keterampilan dalam memanfaatkan sumber daya alam lokal yang dapat dijual sebagai produk ekonomi kreatif masyarakat. Kata Kunci : Kelapa, Virgin Coconut Oil, Desa Labuan
Green School Management in State High School Nurkhasanah, Nurkhasanah; Wuryandini, Endang; Sudana, I Made
Scaffolding: Jurnal Pendidikan Islam dan Multikulturalisme Vol. 7 No. 3 (2025): Pendidikan Islam dan Multikulturalisme
Publisher : Institut Agama Islam Sunan Giri (INSURI) Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/scaffolding.v7i3.8215

Abstract

This study analyzes the management of the green school program at Bandar 1 State Senior High School, Batang Regency, with a focus on planning, implementation, and supervision. A qualitative phenomenological method was used to explore the experiences of the school community. The research was conducted directly by the researcher through observation, face-to-face interviews with informants, and documentation of green school activities and administration. The data obtained were collected for data filtering to become concise and focused data, data presentation in the form of narrative text, and ended with conclusions and verification (Miles and Huberman, 2019). The results of the study show 1) Planning is carried out at the beginning of the school year by involving the school community including the preparation and/or adjustment of the school's vision and mission, preparing the Education Unit Curriculum (KSP) and the School Budget Activity Plan (RKAS); 2) The implementation of green schools includes a) school policies that support environmental care such as socializing the school's vision and mission through social media, managing organic and inorganic waste, managing water and electricity wisely, and innovating environmentally friendly behavior; b) Implementation of environmentally friendly curriculum through planning and implementation of environmental-based learning, habituation of clean and healthy living, extracurricular activities that care about the environment in the form of ENVIRO and honey bees; c) Implementation of environmentally friendly supporting facilities is realized in the form of providing cleanliness facilities and environmental management such as the provision of clean water, separate trash bins, sanitation management, school forests and gardens, green open spaces and gazebos for learning; d) Implementation of participatory-based activities in the form of involvement of all school residents in cleanliness programs, management of school gardens, involvement in various environmental actions and support from parties outside the school such as the Environmental Agency (DLH) and the Agriculture Agency; 3) Supervision is carried out routinely after the end of activities, monthly, quarterly, end of semester and end of school year by comparing achievements with the initial targets of the green school program.
Co-Authors A'Yun, Qurotul AA Sudharmawan, AA Abdul Rahman Wahid Abdul Wahid Suleman Ade Irawan Adiba, Thoriq Ahmad, Aunillah Albab, Farah Qistih Alif Muarifah Amalya Nurul Khairi Amini, Nurul Fajar Anisah, Retnani Anjani, Arlian Sherly Aprilia, Kartini Arie Kurniawan Aryastuti, Nurul Athifah Candra Dewi Ayu Shabrina Baroroh, Erli Carmel Meiden Chasanah, Hikmah Rochimatul Daipadli Daipadli Deni Firmansyah Dianingsig, Dianingsih Elya Zulfa, Elya Endang Wuryandini, Endang Farah Qistih Albab Fitrilya Mustikahati Yusuf, Fitrilya Mustikahati Flora Pasaru Hamzah Karim, Siti Aminah Harni, Harni Humaya, Humaya I Made Sudana Ika Dyah Kumalasari Ika Kumalasari Irawati, Riana Jailani, Muhammad Taufiq Bin Mohd Jayadinata, Asep Kurnia Jihad Lukis Panjawa Kariza, Alifia Ninda karmila karmila Kautsar, Akhmad Khairi, Amalya Nurul Laela Hayu Nurani Lengkong, Siti Nur Asyura Lola Angelita Lolita Sary Lovrina Rahmi Zulkarmen Mahdi, Lukman Maknun, Lu'lu'ul Meta Safitri Moch. Saiful Bachri Muhammad Amiruddin Muhammad Syakbani Murinto Murinto Nada, Rafa Nanik Sulistyani Neni Fidya Santi Nihayati, Nihayati Ningsih, Nur Cahyati Nofa Risma Azis Nugroho, Bondan Nur Ahmad, Nur Nuranisa, Nuranisa Nurul, Amalya Ofa Suzanti Betha Pramudianti, Ulfa Rahma Puri, Putri Ratna Rabiatul Adawiyah Rahman, Ika Ristia Ramadani, Cahya Ricke Desyratnaputri Rizka Indri Arfianti Rizky H. Mawardi Rostika, Rostika Sabrina Dahlizar Sapto Yuliani Saputri, Ginanjar Zukhruf Sepitriani, Sepitriani Siti Pandanwangi TW Siti Pandawangi TW Siti Sarifah Soedjono Soedjono Tokay, Anwar Tri Yanuarto Tri Yanuarto Utami, Zhazha Zetira W, Ratna Kurnia Wiwin Lismidiati Wulandari, Dita yesi budiarti, yesi Yuni Anggraeni Yunni Arnidha, Yunni Zuniarto, Ahmad Azrul