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All Journal International Journal of Public Health Science (IJPHS) Sainteks JURNAL GIZI INDONESIA AGROTEKBIS Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing) Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Farmasi Sains dan Komunitas Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JPI Jurnal Kesehatan Komunitas JECCE (Journal of Early Childhood Care and Education) JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline Diklat Review : Jurnal manajemen pendidikan dan pelatihan SCAFFOLDING: Jurnal Pendidikan Islam dan Multikulturalisme Jurnal Abdi Insani JURNAL AKUNTANSI Jurnal Wahana Pendidikan Jurnal Ilmiah Pharmacy Euler : Jurnal Ilmiah Matematika, Sains dan Teknologi Journal of Agri-Food Science and Technology (JAFoST) Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Sains dan Praktis Journal of Halal Science and Research Jurnal Primagraha Journal of Pharmaceutical and Sciences. JIMPI: Jurnal Inovatif Manajemen Pendidikan Islam Jurnal Pengabdian Kompetitif Asian Journal of Social and Humanities
Nurkhasanah Nurkhasanah
Universitas Ahmad Dahlan
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Analisis Kadar Senyawa Bioaktif dan Aktivitas Antioksidan Beras Hitam (Oryza sativa L. indica) dan Kacang Hijau (Vigna radiata L.) Imelda Afriana Putri; Any Guntarti; Sapto Yuliani; Nurkhasanah Nurkhasanah
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 2 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i2.1312

Abstract

Introduction: Excessive free radicals can induce oxidative stress and contribute to the pathogenesis of various degenerative diseases, necessitating the availability of effective antioxidants. Black rice (Oryza sativa L. indica) and mung bean (Vigna radiata L.) are recognized as rich sources of bioactive compounds with prospective antioxidant properties. Objective: This study aimed to analyze the bioactive compound content and antioxidant activity of black rice and mung bean extracts. Methods: Extraction was performed using maceration with 80% ethanol containing 3% citric acid for black rice and 70% ethanol for mung bean. Total anthocyanin and total polyphenol contents were determined in black rice extract, while total polyphenol and total flavonoid contents were analyzed in mung bean extract. Antioxidant activity was evaluated using the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay. Results: Black rice extract exhibited total anthocyanin content of 0.802 ± 0.009 mg/g and total polyphenol content of 7.798 ± 0.178 mg GAE/g. Mung bean extract demonstrated total polyphenol content of 15.113 ± 0.396 mg GAE/g and total flavonoid content of 11.052 ± 0.243 mg QE/g. The DPPH assay revealed IC₅₀ values of 3.252 ± 0.269 ppm for vitamin C, 76.692 ± 2.250 ppm for black rice extract, and 102.130 ± 2.268 ppm for mung bean extract. Conclusion: Black rice extract exhibited superior antioxidant activity compared to mung bean extract, as indicated by its lower IC₅₀ value. Both extracts demonstrated moderate to strong antioxidant potential, suggesting their promising application as natural antioxidant sources for functional food development.
Nutritional profile and immunomodulatory potential of a polyherbal honey formulation for stunted children Akrom Akrom; Titiek Hidayati; Arif Budi Setianto; Laela Hayu Nurani; Ikhwan Dahlan Rais; Nurkhasanah Nurkhasanah; Lukman Hardia; Prasasti Bintarum; Muslih Anwar
International Journal of Public Health Science (IJPHS) Vol 15, No 3: September 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i3.23026

Abstract

Stunting remains a major public health challenge in Indonesia and has been linked to immune dysregulation, including increased pro-inflammatory TNF-α and reduced anti-inflammatory IL-4 activity. Nutrient-dense polyherbal supplementation may provide a complementary strategy to support nutritional status and immune function. This experimental study investigated the nutritional composition and immunomodulatory activity of polyherbal honey (PHH) formulated with curcuma xanthorrhiza, black cumin seeds, and honey. Vitamins, minerals, and bioactive constituents were characterized using laboratory assays. The immunomodulatory effects of PHH were subsequently evaluated in HTB-183 cells by measuring IL-4 and TNF-α expression after exposure to different formulation concentrations. The analysis confirmed the presence of vitamins A, C, and E; calcium and potassium; and several bioactive compounds in the PHH formulation. PHH exposure increased IL-4 expression and reduced TNF-α expression relative to untreated cells, although the magnitude of these responses varied across concentrations. These findings demonstrate that PHH contains nutritional and phytochemical constituents with potential immunomodulatory activity. Further preclinical and clinical investigations are required to determine its efficacy and safety as complementary nutritional support for children with stunting.
Co-Authors A'Yun, Qurotul AA Sudharmawan, AA Abdul Rahman Wahid Abdul Wahid Suleman Ade Irawan Adiba, Thoriq Ahmad, Aunillah Akrom, Akrom Albab, Farah Qistih Alif Muarifah Amalya Nurul Khairi Amini, Nurul Fajar Anisah, Retnani Anjani, Arlian Sherly Any Guntarti Aprilia, Kartini Arie Kurniawan Arif Budi Setianto Aryastuti, Nurul Athifah Candra Dewi Ayu Shabrina Baroroh, Erli Carmel Meiden Chasanah, Hikmah Rochimatul Daipadli Daipadli Deni Firmansyah Dianingsig, Dianingsih Elya Zulfa, Elya Endang Wuryandini, Endang Farah Qistih Albab Fitrilya Mustikahati Yusuf, Fitrilya Mustikahati Flora Pasaru Hamzah Karim, Siti Aminah Harni, Harni Humaya, Humaya I Made Sudana Ika Dyah Kumalasari Ika Kumalasari Ikhwan Dahlan Rais Imelda Afriana Putri Irawati, Riana Jailani, Muhammad Taufiq Bin Mohd Jayadinata, Asep Kurnia Jihad Lukis Panjawa Kariza, Alifia Ninda karmila karmila Kautsar, Akhmad Khairi, Amalya Nurul Laela Hayu Nurani Lengkong, Siti Nur Asyura Lola Angelita Lolita Sary Lovrina Rahmi Zulkarmen Lukman Hardia Mahdi, Lukman Maknun, Lu'lu'ul Meta Safitri Moch. Saiful Bachri Muhammad Amiruddin Muhammad Syakbani Murinto Murinto Muslih Anwar Nada, Rafa Nanik Sulistyani Neni Fidya Santi Ningsih, Nur Cahyati Nofa Risma Azis Nugroho, Bondan Nur Ahmad, Nur Nuranisa, Nuranisa Nurul, Amalya Ofa Suzanti Betha Pramudianti, Ulfa Rahma Prasasti Bintarum Puri, Putri Ratna Rabiatul Adawiyah Rahman, Ika Ristia Ramadani, Cahya Ricke Desyratnaputri Rizka Indri Arfianti Rizky H. Mawardi Rostika, Rostika Sabrina Dahlizar Sapto Yuliani Saputri, Ginanjar Zukhruf Sepitriani, Sepitriani Siti Pandanwangi TW Siti Sarifah Soedjono Soedjono Sri Winiarti Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tokay, Anwar Tri Yanuarto Tri Yanuarto Utami, Zhazha Zetira Velisa Amanda Putri W, Ratna Kurnia Wiwin Lismidiati Wulandari, Dita Yuni Anggraeni Zuniarto, Ahmad Azrul