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All Journal Jurnal Ilmu Sosial dan Ilmu Politik (JISIP) Jurnal Media Gizi Indonesia (MGI) The Indonesian Biomedical Journal Jurnal Gizi dan Kesehatan Journal of Epidemiology and Public Health Indonesian Journal of Medicine Journal of Maternal and Child Health Reformasi : Jurnal Ilmiah Ilmu Sosial dan Ilmu Politik Pena Justisia: Media Komunikasi dan Kajian Hukum Jurnal Asy-Syukriyyah Nusantara Science and Technology Proceedings Jurnal Inovasi Pembangunan Journal of Advanced Technology and Multidiscipline (JATM) Jurnal Penyakit Dalam Indonesia Jurnal Asy-Syukriyyah Media Penelitian dan Pengembangan Kesehatan Jurnal Farmasi Galenika Jejak digital: Jurnal Ilmiah Multidisiplin Politik Indonesia: Indonesian Political Science Review
Adi Prayitno
Medical School of Sebelas Maret University, Surakarta
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Determination of Total Flavonoid Content and Antioxidant Activity Test of Kelakai Stem and Leaf Extract (Stenochlaena palustris (Burm. F) Bedd) Prayitno, Adi; Muthmainah; Simamora, Helmi Susanti
Nusantara Science and Technology Proceedings The 1st International Conference Muhammadiyah Yogyakarta – Hospital & Healthcare Management
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4211

Abstract

Kelakai plants belong to the Polypodiaceae family and originate from Central Kalimantan. The increasing prevalence of diseases related to oxidative stress has led people to consume natural antioxidants derived from plants. Kelakai plants exhibit antioxidants, anti-inflammatory, and anti-hyperlipidemia activities. Based on these factors, researchers aim to examine the total flavonoid content and determine the antioxidant activity of ethanol extract from the stems and leaves of the kelakai plant (Stenochlaena palustris (Burm. F) Bedd). It is hoped that this study can be an important part of exploring antioxidant compounds obtained from natural materials around us. This study aims to determine the total flavonoid content and understand the antioxidant activity of ethanol extract of Kelakai stems and leaves (Stenochlaena palustris (Burm. F) Bedd). The total flavonoid content was tested using the UV-Vis spectrophotometer method with quercetin standard and expressed in ppm. Meanwhile, the antioxidant activity was determined using the DPPH method, with results expressed in Inhibition Concentration 50% (IC50). The results of the total flavonoid content of ethanol extract were 76.727±0.497 ppm, and the antioxidant activity of ethanol extract of kelakai stems and leaves (Stenochlaena palustris (Burm. F) Bedd) had an IC50 value of 78.787±0.103 ppm, indicating strong intensity and potential
The Effect of Red Dragon Fruit (Hylocereus polyrhizus) on ROS Plasma of Overweight Sprague Dawley Rats Solehah, Novia Zuriatun; Prayitno, Adi; Pamungkasari, Eti Poncorini
Media Gizi Indonesia Vol. 17 No. 2 (2022): JURNAL MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v17i2.144-150

Abstract

Red dragon fruit (Hylocereus polyrhizus) contains antioxidants, namely vitamin C, flavonoids, phenols, and betacyanins that can reduce or inhibit oxidative stress in the body. Excess body weight condition is associated with an increase in oxidative stress due to a decrease in antioxidants. This study was aimed to analyze the effects of red dragon fruit on the level of ROS (MDA) of overweight Sprague-Dawley rats. It used experimental analysis by using pre- and-posttest design with control group. A total sample of 30 male white Sprague-Dawley rats aged 8-12 weeks old with 150-200g of body weight were divided into 6 groups, namely: normal, negative control (KN), positive control (KP), red dragon fruit juice 3.5 g/200gBW (P1), overweight + dragon fruit juice 7 g/200gBW (P2), overweight + dragon fruit juice 10.5g/200gBW (P3) and were observed for 14 days. ROS levels were measured in the beginning and at the end of the intervention by using MDA markers with TBARs method. The results of MDA level measurements were 3.83 ± 0.13 in the KP group, 7.18 ± 0.27 in the P1 group, 5.30 ± 0.30 in the P2 group, and 4.35 ± 0.42 in the P3 group. The results of one-way ANOVA test showed a significant difference in MDA levels in all intervention groups compared to those of the normal and KN groups (p = 0.05). In conclusion, red dragon fruit intake can reduce ROS levels in overweight Sprague-Dawley rats.
Daya Tarik Selebriti Dalam Politik: Studi Kasus Rekrutmen Caleg Artis Oleh Partai NasDem Pada Pemilu 2019 Prayitno, Adi; Putra, Ade Tamara
Jurnal Ilmu Sosial dan Ilmu Politik (JISIP) Vol 13, No 3 (2024): December
Publisher : Universitas Tribhuwana Tungga Dewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jisip.v13i3.3111

Abstract

This research discusses the political recruitment process of the NasDem Party with a study of the nomination of celebrities by the NasDem Party in the 2019 legislative elections. The purpose of this study is to explain the factors behind the NasDem Party choosing to nominate many celebrity figures in the 2019 elections. This study used a qualitative method through descriptive analysis to explain the recruitment mechanism carried out by the NasDem Party in the process of nominating legislative candidates. The data collection technique used was through interviews as primary data and literature study as secondary data. The theoretical framework used in this study is the theory of political parties from Larry Diamond and Richard Gunter and the theory of political recruitment by Pippa Norris. The NasDem Party is the party that recruits and nominates the most celebrities in the 2019 legislative elections. The NasDem Party chooses to nominate celebrities based on several factors and is one of the NasDem Party strategies to raise party votes in the 2019 elections. celebrities in the 2019 elections, including: first, the popularity of celebrities. Second, there is a phenomenon of idol celebrities in several electoral districts. Third, the celebrity factor that is able to become a vote getter.Penelitian ini membahas proses rekrutmen politik Partai NasDem dengan studi pencalonan selebriti oleh Partai NasDem pada pemilu legislatif 2019. Tujuan penelitian ini adalah untuk menjelaskan faktor-faktor di balik Partai NasDem memilih untuk mencalonkan banyak tokoh selebriti pada Pemilu 2019. Penelitian ini menggunakan metode kualitatif melalui analisis deskriptif untuk menjelaskan mekanisme rekrutmen yang dilakukan oleh Partai NasDem dalam proses pencalonan calon legislatif. Teknik pengumpulan data yang digunakan adalah melalui wawancara sebagai data primer dan studi pustaka sebagai data sekunder. Kerangka teori yang digunakan dalam penelitian ini adalah teori partai politik dari Larry Diamond dan Richard Gunter dan teori rekrutmen politik oleh Pippa Norris. Partai NasDem adalah partai yang merekrut dan mencalonkan selebriti terbanyak dalam pemilihan legislatif 2019. Partai NasDem memilih untuk mencalonkan selebriti berdasarkan beberapa faktor dan merupakan salah satu strategi Partai NasDem untuk mengumpulkan suara partai pada Pemilu 2019. Selebriti di Pemilu 2019, termasuk: pertama, popularitas selebriti. Kedua, ada fenomena selebriti idola di beberapa daerah pemilihan. Ketiga, faktor selebriti yang mampu menjadi vote getter.
Pengaruh Fenol dan Saponin pada Madu Hutan Apis Dorsata dan molekul docking pada penanda preeklampsia yusari; Soetrisno; Prayitno, Adi; Wasita, Brian
Journal of Advanced Technology and Multidiscipline Vol. 3 No. 2 (2024): Journal of Advanced Technology and Multidiscipline
Publisher : Faculty of Advanced Technology and Multidiscipline Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jatm.v3i2.60655

Abstract

Molecular docking is an important computational method for drug design. It can be used to predict receptor binding interactions with ligans. In addition, phenol-derived compounds and Saponins are also reported to have various activities such as anti-hypertensive, anti-inflammatory and anti-apoptosis agents. The purpose of this study is to predict whether the Phenol and Saponin compounds are active as anti-inflammatory agents and also to ensure that the binding interactions are stable before and after the docking calculations. The protocol is carried out in accordance with the standards set by the LPPT-UGM Testing Laboratory. The tools, programs, and applications used in this study were Lenovo IdeaPad Flex 5 Processor, AMD Ryzen 5000 Series 5, AutoDock Tools (v1.5.6), Biovia Discovery Studio, AutodockVina, Swiss ADME, VegaZZ, Pubchem, and the and the pkCSM web server (http://biosig.unimelb.edu.au/pkcsm/). Trans-ADFH three-dimensional structure, as a test compound, and Prednisolone, as a standard compound, were downloaded from https://pubchem.ncbi.nlm.nih.gov/. The phytochemical analysis of ADFH includes phenol and saponin. Structure of PlGF 3D (IRV6) and VEGF (4KZN). Identification of ligands and proteins prepared using Pubchem results of molecular docking between preeclampsia through examination of PlGF and VEGF with phenols and saponins Identification of protein ligands using Pubchem, i.e., PlGF (IRV6) with phenol produced 2 interactions and 2 amino acid residues, while saponins produced 2 interactions and 6 residues. pharmacokinetics and toxicity using Swiss ADME, i.e., phenol and saponins are non-mutagenic to bacteria; the maximum safe dose for humans is 0.54 log mg/kg/day; it does not cause toxicity to the heart; the estimated dose for animals is 2.471 mol/kg; it does not cause allergies; it does not cause liver damage; a dose of 0.288 logμ/L can inhibit the growth of 50% of the protozoa T. Pyformis. The content of phenols and saponins in Apis Dorsata forest honey has a high docking score from the original ligand. Molecular docking on phenols and saponins identified PlGF with scores of -2.85, -2.85, and -2.85 kcal/mol, while saponins have +2.84, +2.29, and +2.29 kcal/mol values, which are stated to be better results than the original ligands. This means that phenol has a role as a standard drug that can have an effect on lowering PlGF levels for people with preeclampsia. Molecular docking on VEGF identified phenol with scores of -2.88, -2.88, and -2.88 kcal/mol, and saponins have +1.36, +3.46, and +1.36 kcal/mol values, which are stated to have better results than the original ligands. This means that saponins have a role as a standard drug that can have an effect on increasing VEGF levels for people with preeclampsia.
Geographical Satellite and Survey Data for Prediction of Dengue Cases in Sukoharjo, Indonesia Kusumawati, Dyah; Prayitno, Adi; Dharmawan, Ruben
Journal of Epidemiology and Public Health Vol. 1 No. 1 (2016)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Dengue fever is a disease based on environment and still a health problem. Problems related to the dengue fever vector distribution factor in terms of the spread of vector space with the use of geographic data and survey data in order to predict the incidence of dengue in the region.Subjects and Methods: This study used analytic observational with cross sectional approach using modeling Geographical Information Systems (GIS). The sampling technique in this research is saturated sampling of secondary data Sukoharjo District Health Profile in 2011-2014, population data and data Geographic, then all the data were analyzed using multiple linear regression.Results: There is a positive relationship between the area per Km2 with the number of new cases of dengue fever, although the relationship was not statistically significant. (B = <0:01; CI -0.01 - 0:02; p = 0.310). There is a positive relationship between population density per soul / Km2dengan number of new cases of dengue fever, a significant relationship between population density with DHF cases. (B = <0:01; CI <0:01 to 0:01; p = 0.013). There is a negative relationship between topography per masl by the number of new cases of dengue fever, although the relationship was not statistically significant. (B = <0:01; CI -0.02 - 0:01; p = 0.335). There is a positive correlation between rainfall per mm / yr with the number of new cases of dengue fever, although the relationship was not statistically significant. (B = <0:01; CI <0:01 to 0:01; p = 0101). There is a positive relationship between river flow per ha by the number of new cases of dengue fever, although the relationship was not statistically significant. (B = 0:02; CI -0.01 - 0:03; p = 0318). There is a negative correlation between% Non Flick figure by the number of new cases of dengue fever, although the relationship was not statistically significant. (B = <0:01; CI -0.02 - 0:01; p = 0764).Conclusions: The increase in land area, population density, rainfall, river flow is predicted to affect the increase in dengue cases, whereas the increase ABJ predicted topography and affecting the decline of dengue cases in the district of Sukoharjo in 2011-2014.Keywords: geographical data and survey data, prediction of dengue casesCorrespondence:
ISLAM AS A POLITICAL FORCE READING THE DIRECTION OF ISLAMIC POLITICAL MOVEMENT IN INDONESIA TOWARDS DEMOCRACY Prayitno, Adi
Jurnal Asy-Syukriyyah Vol. 26 No. 1 (2025): Jurnal Asy-Syukriyyah
Publisher : STAI Asy-Syukriyyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36769/asy.v26i1.872

Abstract

This study explores the role of Islam in Indonesia's politics and democracy, focusing on three key aspects: Islam's potential to influence social, economic, and political dynamics; the role of Islamic community organizations like Muhammadiyah and Nahdlatul Ulama in supporting inclusive democracy; and the interpretation and orientation of these organizations post-reform towards democracy. Islamic community organizations serve as pillars of civil society and strategic forces in shaping a more just political order. The research uses a literature review method to identify, evaluate, and synthesize relevant literature to provide insights into the relationship between Islam and democracy in Indonesia. The findings show that Islamic politics address the failures of established ideologies like nationalism, socialism, and capitalism by leveraging values of social justice, brotherhood, and welfare. Post-reform, Islamic organizations like Muhammadiyah and NU have shown substantial contributions to strengthening inclusive democracy through tolerance, diversity, and political stability. However, the study also highlights the challenges posed by extremist groups that reject democracy and use violence as a means of struggle.
ISLAM AS A POLITICAL FORCE READING THE DIRECTION OF ISLAMIC POLITICAL MOVEMENT IN INDONESIA TOWARDS DEMOCRACY Prayitno, Adi
Jurnal Asy-Syukriyyah Vol. 26 No. 1 (2025): Jurnal Asy-Syukriyyah
Publisher : STAI Asy-Syukriyyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36769/asy.v26i1.872

Abstract

This study explores the role of Islam in Indonesia's politics and democracy, focusing on three key aspects: Islam's potential to influence social, economic, and political dynamics; the role of Islamic community organizations like Muhammadiyah and Nahdlatul Ulama in supporting inclusive democracy; and the interpretation and orientation of these organizations post-reform towards democracy. Islamic community organizations serve as pillars of civil society and strategic forces in shaping a more just political order. The research uses a literature review method to identify, evaluate, and synthesize relevant literature to provide insights into the relationship between Islam and democracy in Indonesia. The findings show that Islamic politics address the failures of established ideologies like nationalism, socialism, and capitalism by leveraging values of social justice, brotherhood, and welfare. Post-reform, Islamic organizations like Muhammadiyah and NU have shown substantial contributions to strengthening inclusive democracy through tolerance, diversity, and political stability. However, the study also highlights the challenges posed by extremist groups that reject democracy and use violence as a means of struggle.
Pengembangan Sediaan Gel Ekstrak Bonggol Pisang Ambon Husni, Patihul; Prayitno, Adi; Baitariza, Ardian; Christiningtyas Eryani, Mikhania; Januarti, Melinda
JURNAL FARMASI GALENIKA Vol 12 No 1 (2025): Jurnal Farmasi Galenika
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v12i1.382

Abstract

Ambonese banana (Musa paradisiaca var. Sapientum (L.)) has a tuber with several benefits including for wound-healing. The Ambonese banana tuber contains protein, fat, vitamins A and C. In addition, the tannins, flavonoids, and saponins contained in the sap of the Ambonese banana tuber are beneficial in wound healing. The purpose of this study was to obtain the best gel formula containing extract of Ambonese banana tuber based on physical evaluation. The study was conducted by making three different gel formulations (F1, F2, F3) containing 5% Ambonese banana tuber extract. Physical assessment of the gel preparation included organoleptic tests, pH determination, homogeneity, viscosity, and spreadability evaluation. The results showed that the preparation was in the form of a homogeneous gel with a reddish-brown color and a distinctive odor. The pH of the preparation was around 5-8 with a viscosity between 500-3500 cps and a spreadability of 5-8 cm. F2 is the best gel formula based on physical evaluation during four weeks of storage with a composition of 5% HPMC, 15% propylene glycol, 0.2% methylparaben, 5% Ambonese banana tuber extract, and 100% aquadest.
Pengaruh Proporsi Sekam Bakar terhadap Pertumbuhan dan Produksi Tanaman Sawi (Brassica juncea L.) Merismon, Merismon; Holidi, Holidi; Prayitno, Adi
Jejak digital: Jurnal Ilmiah Multidisiplin Vol. 1 No. 5 (2025): SEPTEMBER
Publisher : INDO PUBLISHING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63822/c262g829

Abstract

Penelitian ini mengevaluasi pengaruh sekam bakar terhadap pertumbuhan dan hasil tanaman sawi (Brassica juncea L.) dengan memanfaatkannya sebagai komponen organik dalam media tanam. Penelitian dilakukan menggunakan Rancangan Acak Lengkap (RAL) dengan enam taraf perlakuan berdasarkan perbandingan tanah dan sekam bakar (4:0, 4:1, 4:2, 4:3, 4:4, dan 4:5), masing-masing diulang empat kali. Parameter yang diamati meliputi jumlah daun, berat basah tanaman, berat akar, dan indeks panen. Hasil penelitian menunjukkan bahwa penambahan sekam bakar berpengaruh nyata terhadap jumlah daun dan sangat nyata terhadap berat basah tanaman. Perlakuan dengan rasio 4:3 dan 4:4 memberikan pertumbuhan vegetatif terbaik, yang diduga disebabkan oleh kondisi media tanam yang lebih optimal dalam hal aerasi, retensi air, dan penyerapan unsur hara. Sebaliknya, rasio sekam tertinggi (4:5) justru menurunkan pertumbuhan tanaman karena porositas yang berlebihan dan ketersediaan hara yang rendah. Berat akar dan indeks panen tidak menunjukkan perbedaan yang signifikan antar perlakuan. Temuan ini menunjukkan bahwa sekam bakar berpotensi meningkatkan pertumbuhan sawi dan mendukung praktik budidaya yang berkelanjutan dan berbiaya rendah melalui pemanfaatan limbah pertanian.
Faktor Elektoral dan Persepsi Kolektif: Studi Explanatory Sequential atas Kemenangan Paslon Pramono-Rano di Pilkada DKI Jakarta 2024 Prayitno, Adi; Otto Malindir, Gaston
REFORMASI Vol 15, No 2 (2025)
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/rfr.v15i2.6952

Abstract

 This study aims to analyze and describe the factors of Pramono-Rano's victory in the 2024 Jakarta Special Region Provincial Election. The approach used in this research is a mixed methods approach with an explanatory sequential design. Quantitative data collection in this study was conducted through the use of electoral survey results. The results of this study indicate that Pramono-Rano's victory in the Election of Governor and Deputy Governor was influenced by several factors; (1) An effective campaign strategy, carried out by Pramono-Rano both directly and indirectly. Directly, the campaign carried out by Pramono-Rano was carried out using the door-to-door method on a massive scale. Pramono-Rano also campaigned massively through billboards, pamphlets, banners and campaign advertisements (indirectly) by raising the slogan "Jakarta Menyala". (2) Pramono-Rano's victory was also supported by the provision of support from Anies Baswedan followed by a shift in the votes of his supporters in Jakarta. (3) Pramono-Rano's victory was also supported by the accumulation of a number of issues that were not beneficial to Ridwan Kamil-Suswono. Starting from Suswono's joke which was considered insulting to the Prophet Muhammad, the Ridwan Kamil-Suswono couple who were considered not to be from Jakarta, to the issue of insults that Ridwan Kamil had once thrown at The Jack.  Penelitian ini bertujuan untuk menganalisis dan menguraikan tentang faktor-faktor kemenangan Pramono-Rano pada Pilkada Provinsi Daerah Khusus Jakarta tahun 2024. Pendekatan yang digunakan dalam penelitian ini adalah mixed methods atau metode campuran dengan desain explanatory sequential. Pengumpulan data kuantitatif dalam penelitian ini dilakukan melalui pemanfaatan hasil survei elektoral. Hasil penelitian ini menunjukan bahwa kemenangan Pramono-Rano pada Pemilihan Gubernur dan Wakil Gubernur dipengaruhi oleh beberapa faktor; (1) Strategi kampanye yang efektif, yang dilakukan oleh Pramono-Rano baik secara langsung maupun tidak langsung. Secara langsung, kampanye yang dilakukan oleh Pramono-Rano dilakukan dengan metode dor to dor secara masif. Pramono-Rano juga masif melakukan kampanye melalui baliho, pamphlet, bener dan iklan kampanye (tidak langsung) dengan mengangkat jargon “Jakarta Menyala”. (2) Kemenangan Pramono-Rano juga didukung oleh adanya pemberian dukungan dari Anies Baswedan diikuti pergeseran suara masa pendukungnya di Jakarta. (3) Kemenangan Pramono-Rano juga didukung oleh akumulasi sejumlah isu yang tidak menguntungkan Ridwan Kamil-Suswono. Dimulai dari candaan Suswono yang dianggap menghina Nabi Muhammad, Pasangan Ridwan Kamil-Suswono yang dianggap bukan berasal dar Jakarta, sampai dengan isu penghinaan yang pernah dilontarkan Ridwan Kamil kepada The Jack.  
Co-Authors A.A. Ketut Agung Cahyawan W Ambar Mudigdo Ansiska, Paisal Ardian Baitariza, Ardian Bambang Purwanto Billah, Muhammad Muayyad Brian Wasita Budiyanti Wiboworini Dono Indarto Dyah Kusumawati Eti Poncorini Pamungkasari Falah Indriawati Barokah, Falah Indriawati Hermanu Joebagio Hermawati Thamrin Holidi Holidi Ida Nurwati Jabar, Laode Abdul Jamaludin, Hamzah Januarti, Melinda JB. Suparyatmo, JB. Malindir, Gaston Merismon, Merismon Mikhania Christiningtyas Eryani Muthmainah Muthmainah Muthmainah Naharani, Adrestia Rifki Novia Zuriatun Solehah Nurochim, Erna Otto Malindir, Gaston Pancarini, Ety Paramasari Dirgahayu Patihul Husni Poncorini, Eti Putra, Ade Tamara Rachmi Fauziah Rahayu RUBEN DHARMAWAN SANTOSO SANTOSO Simamora, Helmi Susanti Soetrisno Soewondo, Widiastuti Sugiarto S Tri Marta Fadhialh, Tri Marta Ulya, Lulu Fathnatul Veithzal Rivai Zainal Yulia Nur Khayati yusari