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Antifungi Candida albicans, Aspergilus fumigatus, dan Pitosporum ovale Dari Sediaan Sampo Probiotik Kombucha Bunga Telang (Clitoria ternatea L) Sebagai Produk Bioteknologi Farmasi Rezaldi, Firman; Agustiansyah, Lucky Dita; Safitri, Endang; Oktavia, Swastika; Novi, Cory
Pharmaqueous: Jurnal Ilmiah Kefarmasian Vol. 4 No. 1 (2022): Volume 4, Nomor 1, Mei 2022
Publisher : Universitas Al-Irsyad Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36760/jp.v4i1.225

Abstract

Penelitian ini bertujuan untuk membuat sediaan sampo probiotik yang berbahan aktif lauutan fermentasi kombucha bunga telang (Clitoria ternatea L) sebagai produk bioteknologi farmasi yang berpotensi dalam menghambat pertumbuhan fungi penyebab ketombe. Mikroba penyebab ketombe yang dimaksud dalam penelitian ini diantaranya adalah Candida albicans, Aspergillus fumigatus, dan Pitosprorum ovale. Sediaan sampo dibuat dengan 4 perlakuan formula yaitu konsentrasi 0%, 20%, 30%, dan 40% serta sampo pasaran sebagai kontrol positif. Pengujian antifungi dilakukan dengan metode difusi cakram dari konsentrasi secara keseluruhan. Data hasil rata-rata diameter zona hambat dianalisis menggunakan statistik yaitu ANOVA satu jalur kemudian dilanjutkan dengan uji post hoc. Hasil penelitian telah membuktikan bahwa sediaan sampo probiotik yang berbahan aktif larutan fermentasi kombucha bunga telang memiliki daya hambat terhadap ketiga pertumbuhan fungi. Konsentrasi 40% merupakan konsentrasi terbaik dalam menghambat pertumbuhan ketiga fungi, sehingga berpotensi sebagai produk bioteknologi farmasi khsusnya pada sediaan sampo probiotik.
EVALUASI RISIKO KESEHATAN AKIBAT PAPARAN LOGAM BERAT DALAM AIR MINUM: STUDI EPIDEMIOLOGI LINGKUNGAN Butarbutar , Augustinus Robin; Dewi, Rd. D. Lokita Pramesti; Auliani , Restu; Farlina, Baiq Fina; Oktavia, Swastika; Wiranti, Bhakti; Apsari, Desy Ari
Jurnal Review Pendidikan dan Pengajaran Vol. 7 No. 1 (2024): Volume 7 No 1 Tahun 2024
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jrpp.v7i1.26104

Abstract

Penelitian ini bertujuan untuk mengevaluasi risiko kesehatan yang mungkin timbul akibat paparan logam berat dalam air minum melalui pendekatan studi literatur dengan fokus pada aspek epidemiologi lingkungan. Identifikasi logam berat seperti timbal, merkuri, kadmium, dan arsenik dalam air minum menjadi titik fokus, sementara dampak kesehatan yang mungkin terkait dengan paparan tersebut dianalisis secara mendalam. Temuan literatur menunjukkan bahwa paparan logam berat dapat menyebabkan gangguan sistem saraf, masalah perkembangan pada anak-anak, dan peningkatan risiko penyakit kronis. Variabilitas geografis dan lingkungan dalam distribusi logam berat juga diungkapkan sebagai faktor penting yang memengaruhi risiko kesehatan. Kritik terhadap metodologi penelitian dalam literatur menggarisbawahi kebutuhan akan konsistensi dan standar yang lebih tinggi dalam penelitian masa depan.
Chemical Profiling of Essential Oil Extracted from Fresh Walang Leaves (Etlingera walang (Blume) R. M. Sm.), an Indigenous Species in Banten, Indonesia Novi, Cory; Apriliane, Keukeu Listia; Oktavia, Swastika
Bioeksperimen: Jurnal Penelitian Biologi Vol 10, No 1: March 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v10i1.22998

Abstract

Essential oils are a group of secondary metabolite compounds that have a distinctive aroma and are volatile. Walang leaves are one of the plants suspected of having essential oil content. This study aims to determine the constituent components of essential oil compounds from fresh walang leaves. The method used to extract essential oil from fresh walang leaves is steam distillation. The essential oil produced was analyzed using Gas Chromatography Mass Spectroscopy (GC-MS). The results showed that the essential oil of fresh walang leaves contained 15 components of essential oil compounds and 2 main components of essential oil compounds, namely: Acetic acid (CAS) Ethylic acid 24.52%, 1,2 Benzenedicarboxylic acid, bis(2-methylpropyl) ester (CAS) Isobutyl phthalate 21.09%.
Efek Penambahan Limbah Lokal Jerami Dan Sekam Padi Bagi Pertumbuhan Jamur Tiram Putih (Pleurotus ostreatus) Shobah, Afifah Nur; Oktavia, Swastika
Bioeksperimen: Jurnal Penelitian Biologi Vol 5, No 2: September 2019
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v5i2.9233

Abstract

White oyster mushroom (Pleurotus ostreatus) is a group of microscopic fungi that are used as food.  P. ostreatus is cultivated in an artificial medium derived from sawdust and has been sterilized. However, the use of sawdust also has problems. Straw and husk of rice can be used as mushroom growing media because they contain organic ingredients such as cellulose, hemicellulose, and lignin. This study aimed to know the growth of white oyster mushroom (P. ostreatus) on straw and husk of rice as an artificial medium and to know the best composition of straw and husk of rice that can be got highly produced of white oyster mushroom (P. ostreatus). The methods of this research were experimental with ten treatments and included several stages including preparation of tools, materials and research sites, the stage of cultivation of P. ostreatus and data collection. This study used an experimental method with a completely randomized design consisting of 40 experimental units. The results obtained were the most optimal P. ostreatus mycelium growth in K1J2S1 treatment with a mean growth rate of 30,60 cm / 30 days, the highest wet weight was K3J1S0 which was 85,83 g while the highest dry weight was in K1J2S1 treatment that is equal to 8,71 g.
PENGARUH PENDAMPINGAN ORANG TUA TERHADAP KESEHATAN MENTAL SISWA SEKOLAH DASAR DALAM PEMBELAJARAN JARAK JAUH DI SDN PALURAHAN KABUPATEN PANDEGLANG BANTEN Andri Imam Subekhi; Swastika Oktavia
Jurnal Kesehatan Tujuh Belas (Jurkes TB) Vol. 3 No. 2 (2022): Mei
Publisher : Sekolah Tinggi Ilmu Kesehatan Tujuh Belas, Karanganyar, JAwa, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Distance learning conducted online should be the responsibility of parents to accompany their children as a substitute teacher. The purpose of this study was to determine the effect of parental assistance on the mental health of elementary school students in distance learning. The qualitative method was carried out with a case study approach, and with 10 participants, 5th grade students in an elementary school in Pandeglang. The students are 9-10 years old. Sampling was done by purposive sampling and data analysis was done descriptively. In this study, two data collection techniques were used, namely questionnaires and interviews. From the results of the study, it can be concluded that parental assistance has an effect on the mental health of elementary school students in distance learning. However, it was found that there were many factors that hindered parental assistance. One of the main inhibiting factors was the busyness of parents and the readiness of parents as substitute teachers. During distance learning, children feel bored due to monotonous learning and children are more likely to be addicted to cellphones
Penerapan Pembelajaran Matematika Kontekstual Terkait Kesehatan untuk Meningkatkan Pemahaman Siswa di Sekolah Dasar Andri Imam Subekhi; Teguh Ardianto; Swastika Oktavia
Jurnal Kesehatan Tujuh Belas (Jurkes TB) Vol. 4 No. 1 (2022): November 2022
Publisher : Sekolah Tinggi Ilmu Kesehatan Tujuh Belas, Karanganyar, JAwa, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This Classroom Action Research (CAR) aims to improve elementary school students' understanding in mathematics learning through the application of a contextual approach associated with health topics. The focus of the research is to see how the use of health problems in mathematics problems can motivate students to better understand mathematical concepts such as measurement, statistics, and basic arithmetic. This research was conducted in two cycles, with each cycle involving the planning, action, observation, and reflection stages. The results of the study indicate that the use of a health context in mathematics learning can increase students' active participation and their understanding of the material being taught.
PELATIHAN PEMBUATAN SABUN CUCI TANGAN PROBIOTIK FERMENTASI KOMBUCHA BUNGA TELANG KEPADA MAHASISWA FARMASI SMESTER 5 UNIVERSITAS MATHLA’UL ANWAR BANTEN SEBAGAI PENINGKATAN WAWASAN DALAM MATA KULIAH BIOTEKNOLOGI Nurullah Asep Abdilah; Firman Rezaldi; M. Fariz Fadillah; Mu’jijah Mu’jijah; Usman Setiawan; Swastika Oktavia; Meliyawati Meliyawati; Fernanda Desmak Pertiwi
Jurnal Pengabdian kepada Masyarakat Indonesia (JPKMI) Vol. 2 No. 1 (2022): April : Jurnal Pengabdian Kepada Masyarakat Indonesia (JPKMI)
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpkmi.v2i1.118

Abstract

Telang flower kombucha is a probiotic that has the potential to be developed as a functional drink and even an active cosmetic ingredient in the form of hand soap as an effort to break the chain of transmission of COVID-19 and its mutations. The purpose of this activity is to provide additional insight to students, especially in the pharmaceutical study program at the Faculty of Health Pharmacy, Mathla'ul Anwar University, Banten, in utilizing the fermented kombucha solution of telang flower as an active ingredient in environmentally friendly hand soap cosmetics. The results of the activity showed that the service participants had increased knowledge or insight about the importance of using conventional biotechnology products as a new breakthrough in the pharmaceutical field. This can be seen from the increase in the pre-test and post-test which have been conveyed a lot during material exposure during pharmaceutical biotechnology lectures and during training. Participants who have attended training on making probiotic handwashing soap from fermented kombucha flower telang solution are more enthusiastic and understand the importance of the benefits of fermenting kombucha flower telang not only in the functional food sector but also in the potential for environmentally friendly cosmetics.
Aplikasi Kitosan dari Litopenaeus vannamei dan Limbah Baglog dari Pleurotus ostreatus untuk Mendekolorisasi Limbah Cair Batik Swastika Oktavia; Siti Rohmah; Cory Novi
Jurnal Penelitian Pendidikan IPA Vol 10 No 2 (2024): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i2.5859

Abstract

The batik sector generates wastewater containing pigment residue, posing a significant environmental threat if not managed effectively. L. vannamei shells yield chitin, convertible to chitosan for water treatment. Baglogs, comprising mycelium and cellulose, serve as a viable adsorbent. The purpose of this study was to learn about the use shell of L. vannamei and P. ostreatus baglog waste with different lengths of time to decolorization batik industry waste water. The method for testing involves deproteinization with NaOH 1M, demineralization with HCl 2M and deasetylation with NaOH 60%. Chitosan L. vannamei and baglog P. ostreatus (2:25 g/g) waste were put into a container containing 500 mL of batik wastewater with colour content with variations of 0, 12, 24, 48, 72, 96, and 120 hours. Further, the capacity of adsorption chitosan and baglog waste are determined using a UV-Vis spectrophotometer during the decolorization process in batik industry waste water using shell of L. vannamei and P. ostreatus baglog waste are 96 hours with a decolorization rate of 90.05%.
Aktivitas Penghambatan α-Glukosidase secara in vitro dan in silico serta Penurunan Glukosa Darah pada Mencit dari Ekstrak Etanol Biji Gandaria (Bouea macrophylla) Tarso Rudiana; Eneng Elda Ernawati; Ayu Sunayah; Nuzulia Romadlotun Nikmah; Hasanah Hasanah; Siti Sawalia; Lia Permatasari; Arini Khaerunnisa; Dimas Danang Indriatmoko; Swastika Oktavia; Siti Nurbayti; Muhammad Ihda Hamlu Liwatu Zein
Jurnal Kartika Kimia Vol 9 No 1 (2026): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v9i1.1054

Abstract

Gandaria (Bouea macrophylla) merupakan tumbuhan topis mengandung senyawa golongan fenolik dan flavonoid yang dapat dimanfaatkan sebagai antidiabetes. Penelitian ini bertujuan untuk mengidentifikasi senyawa metabolit sekunder pada ekstrak etanol biji B. macrophylla, menentukan potensi antidiabetes melalui inhibisi enzim α-glukosidase secara in vitro dan in silico serta menentukan penurunan kadar gula darah secara in vivo. Ekstrak etanol biji B. macrophylla memiliki % rendemen sebesar 31,74% dengan kandungan metabolit sekunder seperti flavonoid, fenolik, alkaloid, saponin dan triterpenoid. Hasil analisis UPLCMS/MS ekstrak etanol biji B. macrophylla mengandung senyawa asam 3,4-dihidroksimandelat, larisitrin dan L-(-)-fenilalanin serta dapat menginhibisi enzim α-glukosidase dengan nilai IC50 sebesar 22,5627 µg/mL. Secara in silico senyawa L-(-)-fenilalanin dan larisitrin memiliki nilai energi bebas dan Konstanta inhibisi terbaik pada inhibisi enzim α-glukosidase (PDB ID: 3L4Y). Studi in vivo ekstrak etanol biji B. macrophylla dapat menurunkan kadar gula darah pada mencit Mus muscullus yang diinduksi aloksan sebesar 63,0 % pada dosis 500 mg/kg BB. Senyawa golongan fenolik dan flavonoid diduga berperan dalam menginhibisi enzim α-glukosidase secara in vitro dan in silico serta dalam menurunkan kadar gula darah mecit.
Co-Authors Abdilah, Nurullah Asep Abdillah, Nurullah Asep Afifah Nur Shobah Agus Setiawan Agustiansyah, Lucky Dita Andri Imam Subekhi Andri Imam Subekhi Andri Imam Subekhi Apriliane, Keukeu Listia Apsari, Desy Ari Arini Khaerunnisa Arini Khaerunnisa Arini Khaerunnisa Augustinus Robin Butarbutar Auliani , Restu Ayu Febi Lestari Ayu Sunayah Ayu Widianingsih Candra Junaedi Cory Novi Cory Novi Cory Novi Cory Novi Dewi, RD. D. Lokita Pramesti Dhyneu Dwi Jayantie Dimas Danang Indriatmoko Dimas Danang Indriatmoko Dinda Hendrarin Putri Dwi Marwati Juli Siswanti E. Egriana Handayani Eka Yulli Kartika Endang Safitri Eneng Elda Ernawati Eneng Elda Ernawati Eva Sutihat Fajrin Noviyanto Fakihah Wardatun Aljanah Farlina, Baiq Fina Fathurrohim, Muhammad Faizal Fernanda Desmak Pertiwi Fernanda Desmak Pertiwi Gina Siti Nurhayati Hadi Susilo hasanah hasanah Hilda Nurpadiana Hujaji, M. Indriatmoko, Dimas Danang Iryana, Irfan Jayantie, Dhyneu Dwi Kartika, Eka Yulli Keukeu Listia Apriliane Lia Permatasari M. Fariz Fadillah M. Fariz Fadillah Mardianto Meliyawati Meliyawati Meliyawati Mu'jijah, Mu'jijah Mu’jijah Muhammad Ihda Hamlu Liwatu Zein Mu’jijah Mu’jijah Mu’jijah, Mu’jijah Nani Suryani Nisa Haerunissa Nur Hidayati Nurhakiki, M. Nurhayati, Ghina Siti Nurpadiana, Hilda Nuzulia Romadlotun Nikmah Pertiwi, Fernanda Desmak Putra, Anca Suryadi Putri, Imrana Roudotussaadah Roudotussaadah Safitri, Endang Shobah, Afifah Nur Siswanti, Dwi Marwati Juli Siti Nurbayti Siti Rohmah Siti Sawalia Suyamto Suyamto Tarso Rudiana, Tarso Teguh Ardianto Tuti Setiawati Usman Setiawan Wiranti, Bhakti