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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Penelitian Kesehatan Suara Forikes JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Media Ilmu Kesehatan PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Farmasi Indonesia JFIOnline Jurnal Mandala Pharmacon Indonesia Jurnal Biomedika Health Information : Jurnal Penelitian Science Midwifery International Journal of Clinical Inventions and Medical Sciences (IJCIMS) Indonesian Journal of Global Health research Open Access Indonesian Journal of Medical Reviews Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Abdimas Altruis: Jurnal Pengabdian Kepada Masyarakat Jurnal Multidisiplin Madani (MUDIMA) East Asian Journal of Multidisciplinary Research (EAJMR) Formosa Journal of Science and Technology (FJST) Indonesian Journal of Pharmacy and Natural Product Jurnal Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Kunir: Jurnal Farmasi Indonesia (KJFI) Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Wiwin Herdwiani
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A Cytotoxic Activity of Ethanol Extract of Yellow Root Stem (Arcangelisia flava (L.) Merr.) and Its Effect on Expression of Bcl-2 and Bcl-xL Genes in MCF-7 Cells Safitri, Devita; Frihani, Assyifa Adelia; Nisa, Sabila Alfa; Kresnadipayana, Dian; Herdwiani, Wiwin
Biomedika Vol 15 No 2 (2022): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/biomedika.v15i2.1309

Abstract

Breast cancer was the main cause of death in women on the world, the percentage of breast cancer deaths in Indonesia reaching 9.6% with a prevalence of 201,143 cases of total cancer cases in 2020. The increasing incidence of breast cancer caused the use of breast cancer drugs to increase, especially natural ingredients that could be used as an alternative treatment for breast cancer with minimal side effects. Yellow root (Arcangelisia flava (L.) Merr.) contained berberine compounds which was known to have cytotoxic activity. he aim of this study was to determine the cytotoxic activity of the yellow root stem extract (Arcangelisia flava (L.) Merr.) and its effect on the expression of Bcl-2 and Bcl-xL in MCF-7 breast cancer cells. Extraction was obtained by maceration method with 70% ethanol as solvent. The method of testing cytotoxic activity using the MTT method assay at the concentration series (2800; 1400; 700; 350; 175; 87.5; 43.75) μg/ml then calculated the IC50 value using linear regression. The narrative review was conducted by collecting data from various online research journals using the keywords cytotoxicity of extracts of yellow root (Arcangelisia flava (L.) Merr.) AND the effect on the expression of Bcl-2 and Bcl-xL genes in MCF-7 cells. The results of the cytotoxic test showed that the extract had cytotoxic activity against MCF-7 breast cancer cells with an IC50 of 838.67 μg/ml so that the cytotoxic effect was moderate (100-1000 μg/ml) and the results of the study of the effect of protein expression on cancer cells showed that berberine contained in yellow root can reduce the expression of Bcl-2 and Bcl-xL through the mitochondrial intrinsic pathway in MCF-7 breast cancer cells so that it can induce apoptosis induction.
Aktivitas Antihiperglikemia Ekstrak Dan Fraksi-Fraksi Buah Merah (Pandanus Conoideus L) Terhadap Perbaikan Fungsi Ginjal Pada Tikus Diabetes Nefropati Iriani, Sakinah Sarnia; Herdwiani, Wiwin; Wijayanti, Tri
Health Information : Jurnal Penelitian Vol 16 No 3 (2024): September-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v16i3.1457

Abstract

Ringkasan: Latar Belakang: Diabetes nefropati merupakan komplikasi serius diabetes melitus yang memerlukan terapi alternatif. Buah merah (Pandanus conoideus L) kaya senyawa bioaktif dengan potensi antidiabetik dan nefroprotektif. Tujuan: Mengevaluasi aktivitas antihiperglikemia ekstrak dan fraksi-fraksi buah merah terhadap perbaikan fungsi ginjal pada tikus diabetes nefropati. Metode: Penelitian eksperimental randomized controlled trial menggunakan 30 tikus yang diinduksi STZ-NA, dibagi menjadi tujuh kelompok: kontrol normal, kontrol negatif, kontrol positif (pioglitazone 15 mg/kg), ekstrak buah merah (250 mg/kg), fraksi n-heksan (71,42 mg/kg), fraksi etil asetat (17,85 mg/kg), dan fraksi air (128,57 mg/kg). Parameter yang diukur meliputi glukosa darah, kreatinin, mikroalbuminuria, dan histopatologi ginjal. Hasil: Fraksi etil asetat paling efektif menurunkan glukosa darah (98,41%), kreatinin (22,63%), mikroalbuminuria (17,51%), dan memperbaiki kerusakan ginjal dengan kerusakan minimal. Simpulan: Fraksi etil asetat buah merah menunjukkan aktivitas antihiperglikemia dan nefroprotektif superior. Saran: Diperlukan uji klinis untuk mengkonfirmasi efikasi dan keamanan pada manusia.
Efektivitas rimpang kunyit hitam (curcuma caesia roxb.) terhadap penurunan glukosa darah dan perbaikan ginjal tikus diabetes nefropati Aini, Zakiyyah Qurrotul; Herdwiani, Wiwin; Wijayanti, Tri
MEDIA ILMU KESEHATAN Vol 12 No 2 (2023): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v12i2.874

Abstract

Background: Diabetes Mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. Diabetic nephropathy is a degenerative kidney vascular disorder that has a relationship with impaired carbohydrate metabolism or sugar intolerance (Diabetes Mellitus). Black turmeric (Curcuma Caesia Roxb.) is widely used by the community as a traditional medicine and has potential as an antidiabetic.Objective: This study aims to determine the effect of black turmeric extract on decreasing blood glucose levels and its effect on improving kidney histopathology in diabetic nephropathy rats.Method: This research was conducted at the Laboratory of the Center for Food and Nutrition Studies, University of Gajah Mada for the period October-November 2022 consisting of 6 groups. STZ-Na induced rats to obtain a state of hyperglycemia. Examination of blood glucose levels using the GOD-PAP method (enzymatic photometric test).Results: The percentage of blood glucose is decreased levels was 16.75% and repaired kidney histopathology was 6.67% as a score mild damage category (1).Conclusion: Black turmeric rhizome extract (Curcuma Caesia Roxb.) can reduce blood glucose levels and improve kidney function at a dose of 400 mg/kg BW.
Evaluasi dan Pengembangan Model Sistem Informasi Manajemen Rumah Sakit Terkait Skrining Resep Menggunakan Metode End-User Computing Satisfaction di Instalasi Farmasi RSUD Mukomuko Astuty, Meilinda Windy; Peranginangin, Jason Merari; Herdwiani, Wiwin
Indonesian Journal of Clinical Pharmacy Vol 13, No 2 (2024)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2024.13.2.45192

Abstract

Evaluasi sistem informasi manajemen rumah sakit (SIMRS) diperlukan untuk melihat sejauh mana penerapan SIMRS telah berjalan sesuai dengan tujuannya dan dilakukan pengembangan untuk meningkatkan kualitas SIMRS. Skrining resep berbasis teknologi sangat dibutuhkan karena dapat meningkatkan kinerja petugas kefarmasian di instalasi farmasi dan mengurangi medication error. Penelitian ini bertujuan untuk mengetahui hasil observasi dan evaluasi SIMRS, khususnya skrining resep yang telah diterapkan di instalasi farmasi, mengembangkan model desain, dan melakukan implementasi sistem yang telah dirancang. Metode penelitian menggunakan pre-experimental design one group pre-test-post-test, dengan kriteria sampel, yaitu staf farmasi yang terlibat penggunaan SIMRS di instalasi farmasi dalam melakukan kegiatan pelayanan kefarmasian dengan minimal masa kerja selama 6 bulan. Nilai pre-test-post-test diperoleh dari evaluasi sistem menggunakan metode end-user computing satisfaction (EUCS) dengan penyebaran kuesioner kepada sampel penelitian dan data kelengkapan skrining resep berdasarkan observasi langsung terhadap SIMRS di instalasi farmasi. Analisis data pre-test-post-test dari variabel EUCS menggunakan uji frekuensi dan uji Wilcoxon signed rank test. Hasil penelitian menunjukkan bahwa nilai rata-rata pre-test terhadap SIMRS yang sudah diterapkan di instalasi farmasi dari kelima variabel EUCS (content, accuracy, format, ease of use, dan timeliness) termasuk dalam kategori tidak puas dengan nilai 2,18. Pengembangan SIMRS skrining resep menggunakan metode prototipe dengan desain data flow diagram dan entity relationship diagram. Nilai rata-rata post-test yang didapat termasuk dalam kategori puas dengan nilai 3,28. Terdapat peningkatan kepuasan pengguna setelah dilakukan implementasi SIMRS skrining resep di Instalasi Farmasi RSUD Mukomuko dengan nilai p 0,000 < 0,05.
Pengaruh Pemberian Ekstrak Etanol Daun Bandotan (Ageratum conyzoides L.) terhadap Kadar Glukosa Darah dan Malondialdehid pada Tikus Yang Diinduksi Aloksan: The Effect Of Ethanolic Extract Of Bandotan Leaves (Ageratum conyzoides L.) on Blood Glucose and Malondialdehyde Levels in Alloxane Induced Rats Johnes Kalfari; Wiwin Herdwiani; Fitri Kurniasari
Indonesian Journal of Pharmacy and Natural Product Vol. 8 No. 01 (2025): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v8i01.3799

Abstract

Hyperglycemia causes an increase of ROS (Reactive Oxygen Species) in the body, causing oxidative stress and tissue destruction. Oxidative stress occurs through increased levels of Malondialdehyde (MDA) in the blood. Bandotan leaves (Ageratum conyzoides L.) have antihyperglycemic and antioxidant activity from flavonoid compounds are able to minimize Malondialdehyde levels. The following research aims to observe the effect of ethanolic extract of bandotan leaves on blood glucose and malondialdehyde levels in alloxan-induced rats and the effective dose. The study began with extracting bandotan leaves using maceration method and continued with phytochemical screening test. Pharmacological tests were applied to rats, grouped into negative control group (Na-CMC 0.5%), positive control group (Glibenclamid 0.45 mg/kg), and group of bandotan leaves extract with doses of 72,5 mg/kg, 145 mg/kg, and 290 mg/kg. After 14 days of treatment, rats blood was collected to measure glucose levels using a glucometer test and Malondialdehyde levels using a MDA ELISA kit. The results showed bandotan leaves extract had antihyperglycemic and antioxidant effects by the mean of blood glucose and Malondialdehyde levels were significantly different from negative control group. Statistical analysis showed that in antihyperglycemic activity, bandotan leaves extract produced an effective dose at 72.5 mg/kg. In antioxidant activity with the parameter of Malondialdehyde levels, bandotan leaves extract produced an effective dose at 290 mg/kg.   ABSTRAK Hiperglikemia menyebabkan bertambahnya jumlah ROS (Reactive Oxygen Species) dalam tubuh yang akan menimbulkan stres oksidatif dan perusakan jaringan. Stres oksidatif muncul melalui kenaikan kadar malondialdehid (MDA) dalam darah. Daun bandotan (Ageratum conyzoides L.) mempunyai aktivitas antihiperglikemik dan antioksidan dari senyawa flavonoid yang mampu menekan kadar malondialdehid. Tujuan penelitian ini adalah untuk mengamati pengaruh pemberian ekstrak etanol daun bandotan pada kadar glukosa darah serta malondialdehid terhadap tikus yang diinduksi aloksan serta dosis efektifnya. Penelitian diawali dengan mengekstraksi simplisia serbuk daun bandotan dengan metode maserasi dan dilanjutkan uji skrining fitokimia. Uji farmakologi dilakukan terhadap tikus yang dikelompokkan menjadi kelompok kontrol negative (Na-CMC 0,5%), kelompok kontrol positif (Glibenclamid 0,45 mg/kg BB), dan kelompok ekstrak etanol daun bandotan dengan dosis 72,5 mg/kg BB, 145 mg/kg BB, dan 290 mg/kg BB. Setelah perlakuan 14 hari, darah tikus diambil untuk diukur kadar glukosa darah menggunakan glukometer tes dan kadar malondialdehid menggunakan Kit ELISA MDA. Hasil menunjukkan ekstrak daun bandotan memiliki aktivitas antihiperglikemik dan antioksidan dengan rerata kadar glukosa darah dan kadar malondialdehid berbeda signifikan terhadap kelompok kontrol negatif. Analisis statistik menunjukkan bahwa pada aktivitas antihiperglikemik, ekstrak daun bandotan mengahasilkan dosis efektif sebesar 72,5 mg/kg BB. Pada aktivitas antioksidan dengan parameter kadar malondialdehid, ekstrak daun bandotan mengahasilkan dosis efektif sebesar 290 mg/kg BB.
Implementation of Clinical Pharmacy Services for Inpatients with Improvement Strategies Based on SWOT Analysis Firdaus, Muhammad Aisy Akbar; Herdwiani, Wiwin; Wijayanti, Tri
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.7069

Abstract

Pharmaceutical Service Standards in Hospitals are regulated in the Regulation of the Minister of Health of the Republic of Indonesia Number 72 of 2016 on the management of pharmaceutical preparations, medical devices, and consumable medical materials as well as clinical pharmacy services in carrying out pharmaceutical service duties in hospitals. This study aims to evaluate the implementation of clinical pharmacy services in inpatients Hospital X in Surakarta and propose improvement strategies through SWOT analysis. The research method used is quantitative descriptive with a retrospective design. Samples were obtained by purposive sampling technique with pharmacist respondents who were directly responsible for clinical pharmacy services to and inpatient patients. The data analysis used was a validity and reliability test and improvement strategies using SWOT analysis. The results of the study show that clinical pharmacy activities are relatively good except for monitoring drug levels in the blood which have not yet been implemented. It is concluded that the implementation of clinical pharmacy services in inpatients at Hospital X is classified as a good category with a percentage (74%) and is in accordance with PMK No. 72 of 2016 except the unimplemented drug therapy level monitoring. The results of the SWOT analysis of IFAS with a positive result of 0.95 and a positive effas of 0.48 so that the position of the hospital's pharmaceutical installation is in quadrant I so that the right strategy is an aggressive strategy.
Analisa Pengendalian Persediaan Dengan Metode EOQ, JIT dan MMSL DiInstalasi Farmasi Rumah Sakit XXX Kota Mojokerto Doso, Tri; Sunarni, Titik; Herdwiani, Wiwin
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 7 No. 2 (2020): Oktober
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v7i2.2793

Abstract

Pengendalian persediaan (managemen inventory) obat sangat penting karena persediaan obat merupakan permasalahan yang sangat krusial dalam manajemen operasional rumah sakit. Hal ini dikarenakan pengendalian persediaan obat yang tepat dapat berdampak yang kuat terhadap perolehan kembali atas investasi agar dapat melayani pasien dengan baik. Maka persediaan perlu dikelola dengan metode diantaranya Economic Order Quantity (EOQ), Just In Time ( JIT), dan Minimum Maximum Stock Level (MMSL). Tujuan penelitian ini adalah mengetahui pengendalian persediaan obat di Instalasi Farmasi Rumah Sakit XXX Kota Mojokerto serta pengaruh metode EOQ, JIT, dan MMSL terhadap nilai persediaan dan Inventory Turn Over Ratio (ITOR).Rancangan penelitian ini dilakukan secara deskriptif non eksperimental dengan pengambilan data secara retrospektif di Instalasi Farmasi Rumah Sakit XXX tahun 2016-2018. Analisa hasil dengan melakukan pengelompokan persediaan berdasarkan kategori ABC yang selanjutnya diterapkan metode EOQ, JIT, dan MMSL kemudian dibandingan nilai persediaan dan ITOR antara nilai riil dengan nilai perhitungan.Berdasarkan hasil penelitian diperoleh rata-rata nilai persediaan pada tahun 2016-2018 diperoleh nilai persediaan paling efisien dengan selisih paling besar bila dibandingkan dengan nilai persediaan riil yaitu pada metode EOQ dengan nilai persediaan Rp 15.262.175.782,00. Sedangkan pada perhitungan ITOR diperoleh nilai 28,26 kali. Hal ini berarti bahwa pengendalian persediaan pada Instalasi Farmasi Rumah Sakit XXX sudah efisien. Kesimpulan dari penelitian ini adalah pengendalian persediaan obat dan alat kesehatan di Instalasi Farmasi Rumah Sakit XXX Kota Mojokerto sudah efisien bila dibandingkan dengan menggunakan metode EOQ.
Skrining dan Karakterisasi Komponen Self Nano Emulsifying Drug Delivery System (SNEDDS) Atorvastatin Menggunakan Fractional Factorial Design (FFD) Wijayanti, Ifa Rizki; Kuncahyo, Ilham; Herdwiani, Wiwin
Jurnal Mandala Pharmacon Indonesia Vol. 10 No. 2 (2024): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v10i2.546

Abstract

Atorvastatin merupakan obat yang memiliki kelarutan rendah dalam air (BCS kelas II) serta memiliki aktivitas farmakologis sebagai terapi hiperkolesterolemia. Self?nanoemulsifying drug delivery systems (SNEDDS) dianggap sebagai pendekatan yang potensial untuk meningkatkan kelarutan atorvastatin karena stabil dan proses pembuatan yang relatif sederhana. Penelitian ini bertujuan untuk memilih komponen dan rasio komponen SNEDDS atorvastatin menggunakan pendekatan desain faktorial terfraksi (DFT) terhadap parameter waktu emulsifikasi, ukuran droplet, indeks polidispersitas (PDI), zeta potensial, persen transmitan, dan loading obat. Variabel yang digunakan dalam pengembangan SNEDDS atorvastatin adalah tipe dan konsentrasi minyak (capryol 90 dan asam oleat), surfaktan (cremophor RH40 dan tween 80), dan ko-surfaktan (transcutol dan PEG 400). Hasil DFT didapatkan 16 run dengan perbedaan proporsi komponen SNEDDS atorvastatin, kemudian dilakukan karakterisasi parameter kritis meliputi waktu emulsifikasi, persen transmitan, ukuran droplet, loading obat, indeks polidispersitas, dan zeta potensial. Komponen dan rasio komponen SNEDDS atorvastatin ditentukan dengan analisa single factor plot menggunakan program design expert 13. Hasil penelitian menunjukkan capryol 90, cremophor RH40, dan transcutol terpilih sebagai komponen minyak, surfaktan, dan ko?surfaktan yang memiliki kontribusi paling besar dalam pembuatan SNEDDS atorvastatin dengan rasio minyak pada 11,1-37,5 %, rasio surfaktan 36,4-77,8 %, rasio ko-surfaktan 11,1-44,4 %.
Optimisation and Characterisation of Curcumin Nanoparticles with Chitosan-TPP Combination Using Ionic Gelation Method as a Cut Wound Healer setyawan, Ferdinta D; Kuncahyo, Ilham; Herdwiani, Wiwin
East Asian Journal of Multidisciplinary Research Vol. 3 No. 9 (2024): September 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/eajmr.v3i9.10865

Abstract

Curcumin has low oral bioavailability, low solubility, and is easily degraded, making its clinical application difficult. This study aims to determine the effect of optimum concentration and formula of chitosan and TPP in the preparation of curcumin nanoparticles on particle size, zeta potential, adsorption efficiency, and incision wound healing. The optimisation method used simplex lattice design method. There were 8 draft formulas consisting of a combination of chitosan and TPP. Each formula was tested for zeta potential value, adsorption efficiency, particle morphology, and wound healing ability. The optimum formula was then determined and analysed using the simplex lattice design method. The combination of chitosan and TPP with simplex lattice design gives an influence on curcumin nanoparticles which reduces particle size, gives a negative zeta potential value, increases the sorption efficiency of the active substance (curcumin) and accelerates the healing effect of cut wounds in mice. The proportion of chitosan and TPP that can produce the optimum formula using simplex lattice design on the critical parameters of particle size, zeta potential value, sorption efficiency and wound healing ability is chitosan.
Increasing Knowledge, Attitude, and Practice in using Traditional Medicines through Pharmacist’s Education and Mentoring in Mojokerto Andito, Didik; Wijayanti, Tri; Herdwiani, Wiwin
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 14, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.78331

Abstract

Background: The use of traditional medicines globally continues to increase and must be balanced with increased knowledge, attitudes, and practice in using traditional medicines through pharmacist education and mentoring.Objectives: This research aims to determine the description of the use of traditional medicine, the level of knowledge, attitudes, and practice of the community in using it, and the influence of pharmacist education and mentoring on it.Methods: This research design was quasi-experimental with a pre-test and post-test control group with 406 community research subjects. It involved 14 pharmacists in providing education and mentoring through WhatsApp group media by providing material according to the modules prepared. The instrument used a questionnaire developed from previous research and tested for validity and reliability. Data collection was carried out prospectively by the participant-self, and analyzed using the Wilcoxon Signed Ranks Test.Results: This study's total number of respondents was 406, divided into 203 as the intervention group and 203 as the control group. The description of the respondent's KAP level before the intervention is in the medium category and after the intervention is in the high category based on the Wilcoxon Signed Ranks Test results at a 95% confidence level (α=0.05) in the intervention group.Conclusion: The use of traditional medicines in the phytopharmaca class is 3%, standardized herbal medicines are 35%, and jamu is 62%. The level of knowledge, attitudes, and practice of the community in using traditional medicine in Mojokerto Regency is, on average, in the medium category. This research also shows the influence of pharmacist education and mentoring on increasing knowledge, attitudes, and practice scores from medium to high.
Co-Authors - SUHARTINAH Afandi, Mukhamad AMINUDIN Ana Indrayati Andito, Didik Anita K Apriani, Dwi Wulan ARIKA WIDYARINI Armayanti Rindiarko Hasbrianti Astuty, Meilinda Windy Dian Kresnadipayana Dina Maryati Doso, Tri Elfahmi Elfahmi, Elfahmi Endang Sri Rejeki Firdaus, Muhammad Aisy Akbar Fransiska Leviana Frihani, Assyifa Adelia Galih Kurniawan Ika Purwidyaningrum Ilham Kuncahyo, Ilham Imba, Farhan Jason Merari Peranginangin Johnes Kalfari Kurniasari, Fitri Lidia Kurniawati Imanuel Lola’ Tulak Rerung lrfan Zamzani Maryati, Dina Maulita Saraswati MELINDA WIDIANINGRUM Merari Peranginangin, Jason Mia Ariasti Nabila K Nisa, Sabila Alfa Nuraini Harmastuti Opstaria Opstaria saptarini Patricia Alfayu Velix Puspitasari, Ismi Putri Rinda Pratiwi RA. Oetari Rahayu Rahmawati, Ismi Rendati, Hema Novita Rica Rica Rica Rica, Rica Safitri, Devita Sakinah Sarnia Iriani Lihawa Sari R Sari R, Sari Sarimanah, Jamilah Sarimanah, Jamilah Seran, Rumaldus setyawan, Ferdinta D Soemardji AA Sofia, Anna Syamsul Ma'arif Tan MI Titik Sunarni Titik Sunarni Tri Wijayanti Tri Wijayanti Triana Hertiani Wijayanti, Ifa Rizki Yanti, Masyitah Novia Yolanda Yolanda Yolanda Yolanda, Yolanda Yul Mariyah Zahra Zahra Zahra Zahra Zakiyyah Qurrotul ‘Aini Zamzani, Irfan Zulfah, Khairina