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Optimizing Brain-Computer Interfaces for Methampetamine Use Disorder through Quantitative Electroencephalography (QEEG) and Transcranial Doppler Analysis: Article Review Caroline, Maria; Syahrul, Syahrul; Tugasworo, Dodik; Retnaningsih, Retnaningsih; Juswanto, Gerard
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1372

Abstract

A Brain-Computer Interface (BCI) is a system that allows a person to control external devices using only their brain activity. It works by translating brain signals into commands that can be understood by a computer. Several lines of evidence demonstrated the deleterious effect of methamphetamine (MA) on neurological and psychological functions. The use of amphetamines, such as MA, is associated with cerebrovascular complications such as cerebrovascular accidents (CVA) ,hemorrhage, hypoxic damage and vasculitis. Interestingly, while changes to cerebral blood flow (CBF) in response to acute amphetamine exposure have been reported. Transcranial Color Doppler (TCCD) is a non-invasive medical imaging technique that uses ultrasound waves to measure blood flow velocity in the major arteries of the brain, specifically within the circle of Willis. The research paper you referenced explores the use of TCCD as a potential measurement modality for BCIs. Quantitative electroencephalogram (qEEG) is a powerful tool for understanding brain function qEEG can reveal specific brain wave patterns associated with drug addiction, potentially providing insights into the neurobiological mechanisms underlying cravings, withdrawal symptoms, and relapse risk in Methamphetamine User Disorder (MUD). There is growing research interest in using Transcranial dopller as a measurement modality for BCIs.Here are some of the key considerations for using Transcranial doppler in BCIs: Mental Tasks, signal processing and classification, accuracy and reliability. Transcranial doppler provides information about blood flow in specific arteries but lacks detailed spatial information about brain activity. These patterns could vary depending on the type of drug, the severity of addiction, and individual differences. Transcranial doppler in measuring middle cerebral artery (MCA) blood flow velocity parameters (peak systolic velocity (PSV) and mean flow velocity (MFV)). qEEG can help researchers investigate the complex interplay between addiction and other brain disorders, like depression or anxiety. Characteristic qEEG in drugs addiction Increased Theta (4-8 Hz) and delta (1-4 Hz) brain waves are often associated with sleep and relaxation. However, research has shown that individuals with drug addiction may have increased theta and delta activity, particularly in the frontal and temporal regions of the brain. Altered Beta (13-30 Hz) brain waves are generally associated with wakefulness, alertness, and cognitive processing. Studies have observed both increases and decreases in beta activity in individuals with drug addiction, depending on the type of drug, the stage of addiction, and the specific brain regions being examined. The results of this research have important practical implications for building an diagnostic and functional assement with a better understanding of an using technology.
Heterogeneity of Social Returns to Education Across Employees Education Levels in Indonesia Wahyuni, Ribut Nurul Tri; Retnaningsih, Retnaningsih; Yuliana, Lia
Eko-Regional: Jurnal Pembangunan Ekonomi Wilayah Vol 20 No 2 (2025): September 2025
Publisher : Faculty of Economics and Business Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32424/er.v20i2.15782

Abstract

This study estimates the heterogeneity of agglomeration externalities across employees' education levels in Indonesia. This study uses the 2020-2024 microdata and the Instrumental Variable (IV) Heckman model with the historical population density and the number of universities as IVs. The result indicates that social returns to education from the local high-skill labor market, which is a part of agglomeration externalities, are positively significant and higher for high- and medium-skilled employees than for low-skilled employees. This finding demonstrates the efficacy of public education investments, especially Indonesian government policy that can enhance the quantity and quality of university graduates, thereby promoting the transfer of knowledge to all employees and eventually reducing wage inequality between regions.
The Effect of Vitamin D Supplementation on Changes in TNF-? Levels and Exciting Frequency in Epilepsy Patients Daynuri, Riri; Kustiowati, Endang; Husni, Amin; Retnaningsih, Retnaningsih; Suryawati, Herlina; Ardhini, Rahmi
Diponegoro International Medical Journal Vol 6, No 1 (2025): July 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v6i1.26585

Abstract

Background: Epilepsy, a neurological disorder, is a global public health problem. The active form of vitamin-D is 5000IU/day for 42 days, able to push inflammation and change the balance between inhibitory cytokine and excitatory cytokine, to suppress recurrent seizuresObjective: Analyze the effect of vitamin-D 5000 supplementations on changes in TNF-α levels pre-and-post-vitamin-D supplementation and changes in the frequency of seizures pre-and post-vitamin-D supplementation in epilepsy patients.Methods: This research is a quasi-experimental analytic observational study with a pre-and-post-tests approach without control. Subjects were patients diagnosed with epilepsy who had met the inclusion criteria. Previous research subjects were checked for TNF-α levels, then given vitamin-D supplementation of 5000IU/day for 42 days, then rechecked TNF-α levels. Then performed a bivariate analysis.Results:  There was a significant difference between changes in TNF-α pre-and-post-levels of vitamin-D supplementation of 5000IU/day for 42 days (p<0.001). There was a significant difference in the frequency of seizures pre-and-post-levels of vitamin D supplementation 5000IU/day for 42 days (p=0.002). There is a significant relationship between (d)TNF-α on (d)the frequency of seizures pre-and-post-vitamin-D supplementation 5000IU/day, strongly and positively related (p<0.001; r=0.661). There is no relationship between risk factors with (d)TNF-α. There is no relationship between risk factors with (d)seizure frequency.Conclusion: There is a significant difference in the levels of TNF-α pre-and-post-vitamin-D supplementation. There is a significant difference between the frequency of seizures pre-and-post-vitamin-D supplementation. There is a relationship between (d)TNF-α and (d)the frequency of seizures pre-and-post-vitamin-D supplementation.
Limitations of Patients’ Communication with Mechanically Ventilated Patients: A Scoping Review Widaryati, Widaryati; Ismail, Suhartini; Retnaningsih, Retnaningsih; Margawati, Ani; Subu, Muhammad Arsyad
Indonesian Contemporary Nursing Journal (ICON Journal) Vol. 10 No. 2 (2026): Volume 10 Number 2 February 2026
Publisher : Faculty of Nursing, Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/icon.v10i2.44513

Abstract

Aims: This review aimed to examine the effects of communication barriers, identify effective communication strategies, and determine appropriate interaction content for patients receiving mechanical ventilation. Methods: A scoping review approach was conducted using four databases: EBSCOhost, Elsevier, PubMed, and ProQuest, selected for their extensive health-related collections. Eligible studies were published between 2015 and 2025, written in English, and utilized quantitative or qualitative designs. The search incorporated keywords related to communication barriers, ventilated patients, intensive care, and critical care. Data was synthesized through systematic collation, summarization, and reporting. Results: Of 1,239 records identified, 20 studies met the inclusion criteria. Findings indicated that communication challenges affected patients, nurses, and family members, with consequences categorized as psychological and care-related impacts. Two primary communication approaches were identified: unaided and aided methods, with aided strategies further divided into low-technology and high-technology tools. Communication content clustered into three domains: expressing patient needs and desires, conveying complaints, and facilitating care-related interactions. Conclusion: Communication barriers significantly influence the well-being of patients, nurses, and families in intensive care settings. Both unaided and aided communication strategies can enhance interactions with mechanically ventilated patients. Structured communication focusing on patient needs and desires, concerns, and caregiving elements is essential to promote care quality and support patient well-being.
Co-Authors Afina, Siti Agung, Locoporta Aisy, Rihadatul Al Mutanafisa, Tasneem Alfiasari Amalia Khairati Amin Husni Andhitara, Yovita Andhitara, Yovita Andhitara Ani Margawati Ani Ruwani, Ani Anita Saufika Anjani, Gemala Ardhini, Rahmi Arifin Triyanto Arina Hayati Asep Taryana Budisulistyo, Trianggoro Caroline, Maria Daynuri, Daynuri Daynuri, Riri Diah Retno Wahyuningrum Dini Aprilia Dodik Tugasworo Drajat Martianto Dwi Febryanto Endang Gumbira Sa’id Endang Kustiowati Erni Hernawati Purwaningsih, Erni Hernawati Fadila Ramadini Febriantina Dewi Fibria Mustikarini, Fibria Firina Firina Firli Bramantyo, Dion Fitri Octaviana Fitria Handayani Hajijah, Rengganis Novyanti Hamdani, Faishol Handaru Tri Mulyono Hanisa Rahmina Fitriyana Hartono, Jimmy Eko Budi Hartoyo Hartoyo Irni Rahmayani Johan Istiqlaliyah Muflikhati Jaeri, Santoso Jethro Budiman, Jethro Junedi, Rahmat Juswanto, Gerard Kurnianto, Aditya Kurnianto, Aditya Kurnianto Lia Yuliana Lilik Noor Yuliati Martha Irene Kartasurya Megawati Simanjuntak Nana Rochana, Nana Nani Maharani Noni Widiawatie Nuraini Nuraini Pasmanasari, Elta Diah Priambada, Dody Purba, Jan Sudir Puspitawati, Arinta Putri, Ayulia Karisma Putri, Marietta Krisnaya Nandika Putri, Nadya Yona Eka Rahmawati, Dani Rahmayanti Rahmayanti Rahmi Parhati RIA ANGGRAINI Saiful Ridlo Satrioaji, Hari Wahono Sofro, Muchlis AU Achsan Udji Sri Anna Marliyati Subu, Muhammad Arsyad Suhartini Ismail, Suhartini Suryadi Suryadi Suryawati, Herlina Syahrul Syahrul Tamad, Fatiha Sri Utami Tri Rahayu, Fitriani Tri Subekti Trisnaningtyas, Wenny Tsaniadi Prihastomo, Krisna Tugasworo, Dodik ` Ujang Sumarwan W.H, Nugrahaningsih Wahyuni, Ribut Nurul Tri Widaryanti, Widya Bella Widaryati Widaryati Yudiatma, Muh. Firman Yuridis, Melani Sukma