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Gusti Revilla
Bagian Anatomi Fakultas Kedokteran Universitas Andalas, Padang 25163, Indonesia
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Profil Pasien Neurodermatitis di Rumah Sakit Pendidikan Universitas Andalas Tahun 2019-2021 Nur, Fauziah; Yenny, Satya Wydya; Revilla, Gusti; Akhyar, Gardenia; Ashal, Taufik; Khaira, Fathiyyatul
Jurnal Penelitian Perawat Profesional Vol 7 No 3 (2025): Juni 2025, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v7i3.5135

Abstract

Tujuan penelitian ini yaitu mengidentifikasi profil pasien neurodermatitis di Rumah Sakit Pendidikan Universitas Andalas tahun 2019-2021. Jenis penelitian ini adalah penelitian deskriptif retrospektif dengan pendekatan cross-sectional. Penelitian dilaksanakan di Bagian Rekam Medis Rumah Sakit Pendidikan Universitas Andalas pada Januari 2019-Desember 2021. Teknik yang digunakan adalah total sampling dan besar sampel penelitian ini adalah 51. Analisis data menggunakan analisis univariat. Hasil penelitian ini menunjukkan usia terbanyak pasien neurodermatitis berusia 56-65 tahun yaitu 33,3%. Jenis kelamin terbanyak yaitu perempuan 58,8%. Pekerjaan terbanyak yaitu PNS dan ibu rumah tangga masing-masing 27,5%. Keluhan pasien terbanyak yaitu gatal 68,6%. Lokasi lesi paling banyak ditemukan tungkai bawah yaitu 43,1%. Terapi oral terbanyak yaitu setirizin 86,3%. Terapi topikal yang banyak digunakan yaitu emolien 76,5%. Kesimpulan penelitian ini didapatkan bahwa usia 56-65 tahun, jenis kelamin perempuan, pekerjaan PNS dan ibu rumah tangga, keluhan gatal, lokasi lesi tungkai bawah, terapi oral setirizin dan terapi topikal emolien merupakan yang paling banyak ditemukan pada pasien neurodermatitis.
Perbedaan Fungsi Sistolik Ventrikel Kanan antara Hipertensi Arteri Pulmonal dan Hipertensi Vena Pulmonal Rayhansyah, Vito; Yanni, Mefri; Irramah, Miftah; Hamdani, Rita; Revilla, Gusti; Linosefa, Linosefa
Jurnal Biomedika dan Kesehatan Vol 8 No 1 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2025.v8.14-25

Abstract

Background Pulmonary arterial hypertension (PAH) and pulmonary venous hypertension (PVH) are both associated with increased right ventricular (RV) afterload, potentially leading to RV systolic dysfunction. Despite its prognostic value in predicting right heart failure (RHF), echocardiographic evaluation of RV function remains underutilized in the routine assessment of patients with PAH and PVH. Methods This study aims to evaluate differences in RV systolic function between PAH and PVH patients. A total of 116 patients (58 PAH and 58 PVH) were selected through consecutive sampling from medical records at RSUP Dr. M. Djamil Padang. Echocardiographic parameters were analyzed using appropriate statistical tests based on data distribution and type, including Chi-square, Fisher’s exact, and Mann-Whitney U tests. Results Significant differences were observed between PAH and PVH groups in terms of tricuspid regurgitation (TR) severity (p = 0.003), tricuspid annular plane systolic excursion (TAPSE) (p = 0.013), and tissue Doppler-derived systolic velocity of the tricuspid annulus (S′) (p = 0.001). No significant differences were found in ejection fraction (EF), systolic pulmonary artery pressure (sPAP), mean pulmonary artery pressure (mPAP), or TR velocity (TR Vmax). Overall, RV systolic function differed significantly between the PAH and PVH groups (p = 0.006). Conclusions The findings demonstrate a statistically significant difference in RV systolic function between patients with PAH and PVH. These results underscore the need for more comprehensive and routine echocardiographic evaluation of RV function in these populations to enhance risk stratification and management.
Bioaktivitas dan Efek Kesehatan Bawang Hitam terhadap Enzim Reduktase Hidroksi Metilglutaril-KoA Pada Tikus Putih Jantan Obesitas Ibrahim, Ibrahim; Yerizel , Eti; Endrinaldi, Endrinaldi; Revilla, Gusti
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.1039

Abstract

Obesity is a condition of abnormality or excess fat accumulation in adipose tissue. HMG-CoA reductase is an enzyme that can catalyse HMG-CoA into mevalonate, which is needed in cholesterol biosynthesis. Inhibition of the HMG-CoA reductase enzyme is an effective drug target mechanism to overcome dyslipidemia. Black garlic, which is high in antioxidants such as SAC, flavonoids, and polyphenols, is an effective mechanism. This study tested the bioactivity and health effects of black garlic on the activity of HMG-CoA reductase enzyme. This type of experimental study on male rats uses a post-test control-only group design. The sample in this study was 25 experimental animals divided into five groups, group negative control with a regular diet, group positive control with a high-fat diet, group treatment 1 with a high-fat diet and black garlic dose of 200 mg/rats, group treatment 2 with a high-fat and black garlic diet dose of 400 mg/rats, and group treatment given a high-fat diet and black garlic dose of 800 mg/rats. The results of the study showed that the average value and standard deviation of HMG-CoA in the negative control group were 1,044 and 0.088, the positive control group 2,136 and 0.487, the 1 group treatment 1,292 and 0.194, the 2 group treatment 1,296 and 0.206 and the three treatment group 1,201 and 0.201 nmol/min/mg protein. Based on the results of the hypothesis test, the significance level for the five groups was 0.004, indicating a significant difference in the average HMG-CoA levels in groups K1, K2, P1, P2, and P3. Black garlic significantly decreased HMG-CoA reductase activity in rats fed a high-fat diet, supporting its potential as a natural therapeutic agent for dyslipidemia management.
Exploring the Effects of Bone Marrow Mesenchymal Stem Cells on Amyloid Plaque Reduction in a Rat Model of Alzheimer's Disease Annita, Annita; Revilla, Gusti; Ali, Hirowati; Almurdi, Almurdi
Majalah Kedokteran Andalas Vol. 47 No. 1 (2024): MKA Januari 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v47.i1.p79-86.2024

Abstract

Objective: This study aimed to evaluate the therapeutic potential of Bone Marrow-derived Mesenchymal Stem Cells (BM-MSCs) in mitigating amyloid plaque formation in Alzheimer's disease induced by Aluminum Chloride (AlCl3) in rats. Methods: Rats were divided into three groups: negative control, positive control (AlCl3-induced), and treatment (AlCl3 + BM-MSCs). Cognitive function was assessed five days post-induction, and amyloid plaques were quantified using Congo Red staining in the cortex and hippocampus. Results: A significant reduction in amyloid plaque was observed in rats treated with BM-MSCs. The proportion of stained areas decreased from 1.88 to 1.73 in the cortex and from 1.61 to 1.47 in the hippocampus, compared to AlCl3-only controls. Conclusion: BM-MSCs demonstrated a moderate but statistically significant reduction in amyloid plaque in a rat model of Alzheimer's disease, indicating their therapeutic potential.
KARAKTERISTIK KASUS BENDA ASING PADA TELINGA DI INSTALASI GAWAT DARURAT RSUP DR. M. DJAMIL PADANG PERIODE 2017 – 2021 Javandi, Muhammad Rayhan Abiyyu; Huriyati, Effy; Saputra, Deddy; Rahman, Sukri; Firdawati, Firdawati; Revilla, Gusti
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 5 (2025): SINERGI : Jurnal Riset Ilmiah, Mei 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i5.1256

Abstract

Foreign body in the ear is an emergency case in the field of ENT-KL which is often found in the emergency room. Foreign objects found can be insects, seeds, cotton buds, batteries, and others. Foreign objects in the form of insects can cause irritation so that the patient will feel pain. Therefore, for live foreign objects, first aid efforts are needed in the form of dropping edible oil into the ear so that the live foreign objects die and then immediately take them to the nearest health facility. The purpose of this study was to determine the characteristics of cases of foreign bodies in the ear at the emergency department of Dr. M. Djamil Padang for the period 2017 – 2021. This type of research is a retrospective descriptive with a total sampling technique and uses secondary data. Samples that met the inclusion and exclusion criteria were 707 cases. The results of this study showed that the most characteristic distribution of foreign body cases in the ear was: the age group of children (43.4%), male sex (59.3%), types of inorganic foreign bodies (66.2%) with objects foreigncotton bud (49.2%), no symptoms (78.3%), no first aid efforts (86.2%), treatment with extraction (70.2%), and no complications (86%). The conclusion of this study is that the most foreign bodies found in the ear are cotton buds, so education is needed to the public about the use of cotton buds.  
Clinical characteristics of maxillofacial fracture patients in Dr. M. Djamil General Hospital Padang Hafiz, Al; Maidatuz Zahra, Agnesia; Mulyani, Henny; Huriyati, Effy; Revilla, Gusti; Zhuhra, Rahma Tsania
Oto Rhino Laryngologica Indonesiana Vol. 54 No. 2 (2024): VOLUME 54, NO. 2 JULY - DECEMBER 2024
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v54i2.661

Abstract

Background: Maxillofacial fracture consists of several types of fractures depending on their location. Traffic accidents are the most common cause of these cases. The choice of management given in maxillofacial fractures is divided into immediate and planned delayed management, depending on the condition of the injured tissue. Purpose: To describe the clinical characteristics of maxillofacial fracture in the Department of Otorhinolaryngology Faculty of Medicine Universitas Andalas/Dr. M. Djamil General Hospital Padang, in 2020 to 2022. Method: A descriptive study with retrospective approach. The study was conducted by collecting data from the medical record section by using a total sampling technique (59 patients) from 2020 to 2022. Result: The highest cause was traffic accidents (49.2%), the most common findings were nasal bone fracture (44.1%), with operative management (82.4%). Conclusion: Maxillofacial fractures were most commonly experienced by the young age group and caused by traffic accidents, therefore driving safety and driver compliance should be more emphasized. Keywords: maxillofacial fracture, ORIF (Open Reduction Internal Fixation), septorhinoplasty, septoplasty, rhinoplasty ABSTRAK Latar belakang: Fraktur maksilofasial terdiri dari beberapa jenis fraktur tergantung lokasinya. Kecelakaan lalu lintas menjadi penyebab tersering dari kasus ini. Pemilihan tatalaksana yang diberikan pada fraktur maksilofasial dibagi menjadi tatalaksana segera dan tatalaksana lanjutan terencana, tergantung dari kondisi jaringan yang terluka. Tujuan: Untuk mengetahui karakteristik klinis pasien fraktur maksilofasial di Departemen THT-BKL FK Unand/RSUP Dr. M. Djamil Padang, dari 2020 sampai 2022. Metode: Penelitian ini bersifat deskriptif dengan pendekatan retrospektif. Penelitian dilakukan dengan pengambilan data di bagian rekam medik dengan teknik total sampling dan didapatkan sampel sebanyak 59 pasien pada tahun 2020 sampai 2022. Hasil: kelompok usia paling sering adalah 16-30 tahun (54.2%), dengan jenis kelamin terbanyak adalah laki-laki (76.3%), penyebab tersering adalah kecelakaan lalu lintas (4.2%), jenis fraktur tersering adalah fraktur tulang hidung (44.1%), dan tatalaksana paling sering adalah tatalaksana operatif (82.4%) Kesimpulan: Fraktur maksilofasial paling sering dialami oleh kelompok usia remaja dan disebabkan kecelakaan lalu lintas, oleh karena itu keselamatan dan kepatuhan berkendara perlu lebih diperhatikan dan ditingkatkan. Kata kunci: fraktur maksilofasial, ORIF (Open Reduction Internal Fixation), septorinoplasti, septoplasti, rinoplasti
The Relationship of Age with TNF-α Levels in Pregnancy and Abortion Monika, Cici; Revilla, Gusti; Karmia, Hudila Rifa; Nurhajjah, Siti; Welan, Rahmani
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.1.97-107.2026

Abstract

Introduction: Tumor Necrosis Factor Alpha (TNF-α) plays a crucial role in the early control of abortion. This increase can be influenced by age. The purpose of this study was to analyze the relationship between age and TNF-α in both normal pregnancies and abortion. Method: The type of research is analytic with a cross sectional design, collecting samples using total sampling technique, resulting in 36 patients who were subsequently assessed for TNF-α levels at the Biomedical Laboratory of Andalas University. The source of research data is secondary data. Data analysis involved the Spearman correlation test, Independent T-test, and Mann-Whitney test. Result: The average gestational age was younger, the average maternal age was older, and the average TNF-α levels were higher in abortion compared to normal pregnancy. The BMI of all patients was normal. There is a significant difference between age in normal pregnancy and abortion (p = 0.001), there is no relationship between age and TNF-α levels in normal pregnancy (p = 0.429), there is no relationship between age and TNF-α levels in abortion (p = 0.862), and there is no difference in TNF-α levels between normal pregnancy and abortion (p = 0.248). Conclusion: there is a significant difference between age in normal pregnancy and abortion.
Co-Authors Abdul Razak Advin, Tesya Afriani, Nita Afriwardi Afriwardi Al Hafiz ALADIN ALADIN Aljassri, Resti Karunia Almurdi Almurdi Amanda Rizki Annita, Annita Ansharina, Hafiznie Ariani, Peny Ashal, Taufik Asri, Ennesta Aulia Fash Farabi Ayudita Silvia Hasibuan Aziz Djamal Deddy Saputra Deddy Saputra Dedi Sutia Defrin, Defrin Delmi Sulastri Desmawati Desmawati Desmawati Desmawati Dia Rofinda, Zelly Dia Dini Nurhasanah Effy Huriyati Eldi Sauma Elvi Febria Marnita Endrinaldi Erly Indrama Eti Yerizel Fadil Oenzil Fadila, Zurayya Faris Muhammad Fathiyyatul Khaira, Fathiyyatul Firdawati Firdawati Firdawati, Firdawati Fitri Anggini Gardenia Akhyar henny Mulyani Hirowati Ali, Hirowati Husnil Kadri Ibrahim Ibrahim Javandi, Muhammad Rayhan Abiyyu Jella Wisesa Karmia, Hudila Rifa Linosefa Linosefa Maidatuz Zahra, Agnesia Mayetti Mayetti Mefri Yanni Meishinta Fitria Miftah Irramah Milano, Ryan Suheil Monika, Cici Muhammad Iskandar Muhammad Zulfadli Syahrul Musrizal Adli Noverial, Noverial Nur'aisyah, Shafira Nur, Fauziah Nurhasanah, Dini Oktaria Denantika Pipit Amelia Burhani Priyanka Prima Putri Putri Ovieza Maizar Rahmani Welan Rayhansyah, Vito Restu Susanti Rita Hamdani Russilawati, Russilawati Sahputra, Roni Eka Salsa Oktarin Letmi Satya Wydya Yenny Siti Nurhajjah Siti Nurhajjah, Siti Sukri Rahman susi susi Tiffany, Begum Tofrizal Yanni, Mefri Yanwirasti Yanwirasti Yenita Afriyeni Yerizel , Eti Yose Ramda Ilhamdi Yusri, Elfira Zhuhra, Rahma Tsania Zulfadli Syahrul, Muhammad