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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Jurnal Kebidanan Althea Medical Journal Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Majalah Obstetri dan Ginekologi Public Health of Indonesia Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Keperawatan Muhammadiyah Amerta Nutrition Care : Jurnal Ilmiah Ilmu Kesehatan Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan NURSING UPDATE JURNAL ILMIAH ILMU KEPERAWATAN Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology Jurnal Abdi Masyarakat Indonesia Asian Journal of Health Research Strada Jurnal Ilmiah Kesehatan (SJIK) JURNAL KEPERAWATAN

Hermanto Tri Joewono

Department Of Obstetrics And Gynecology, Faculty Of Medicine, Airlangga University

Author-ID : 405201

Humanities Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Increased Brain Derived Neurothropic Factor in the cerebrum and cerebellum of Rattus norvegicus newborn with exposure to Mozart's music in default sequence compared with the reversed sequence and without exposure during gestation Agustina Hidayati; Hermanto Tri Joewono; Widjiati Widjiati
Majalah Obstetri dan Ginekologi Vol. 26 No. 2 (2018): August
Publisher : Universitas Airlangga

Objectives: To analyze the differences in the expression of Brain Derived Neurothropic Factor (BDNF) in Rattus norvegicus cerebrum and cerebellum of newborn between those exposed to Mozart's music composition in default sequence, reverse sequence, and without exposure in the womb.Materials and Methods: Analytical laboratory experimental study with randomized post test only control group design using animal models Rattus norvegicus. The animal models were divided into three groups: control group without any exposure, the treatment groups with exposure to Mozart's music in default sequence and another group in reverse sequence since day 10 of gestation. We used a comparison test in the analysis of BDNF expression.Results: We found significant difference in BDNF expression with p value 0.004 (mean 8.98±1.31 default sequence group, 5.58±3.08 reverse sequence group, 6.80±1.95 control) in the cerebrum. We found significant difference of BDNF expression with p value 0.003 (mean 9.48±1.41 default sequence group, 6.02±3.25 reverse sequence group, 7.14±2.54 control) in the cerebellum. In cerebrum dan cerebellum we found significant difference between standard Mozart’s music and control (cere-brum p=0.018, cerebellum p=0.001), and we found significant difference between standard Mozart’s music and reverse Mozart’s music (cerebrum p=0.001, cerebellum p=0.008) and no significant difference in reverse Mozart and control (cerebrum p=0.264, cerebellum p=0.490)Conclusion: Sequence in Mozart’s music is very important in increase expression of BDNF.

Default sequence of Mozart’s compositions during pregnancy gave higher dendritic density in the cerebrum and cerebellum of Rattus norvegicus offsprings compared with reversed sequence and control Harry Mangasi Binsar Panjaitan; Hermanto Tri Joewono; Widjiati Widjiati
Majalah Obstetri dan Ginekologi Vol. 27 No. 1 (2019): April
Publisher : Universitas Airlangga

Objectives: This study aim to determine sequence of Mozart songs in the analyzing differences in dendritic density of cerebellum and cerebellum of new born Rattus novergicusMaterials and Methods: Experimental study randomized post test only control group design using Rattus norvegicus. Animal subjects were divided into three groups which were control group, and the treatment group that were given exposure to default sequence and reversed sequence of Mozart's music from gestation day 10. We used a comparison test in the analysis expression of BDNF.Results: In the cerebrum there was a significant difference in the Mozart group in reverse rather than with Mozart standard sequence and in standard Mozart group with no exposure group, with p=0.003 and p=0.000. In the cerebellum there was a significant difference in the group in reverse rather than with standard Mozart and in the standard Mozart group with the control group, with p=0.000 and p=0.000. However, there was no significant difference between control group and Mozart group upside down in cerebrum and cerebellum with p=0.109 and p=0.077Conclusion: The density of dendrites in the cerebrum and cerebellum of Rattus norvegicus newborn exposed to Mozart's music during pregnancy with standard Mozart sequence was higher than that in those receiving reverse order and without exposure. There were no significant differences between the density of the cerebrum and cerebellum dendrites between groups exposed to reversed sequence of Mozart composition and those without exposure.

FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus Fitria Desky; Hermanto Tri Joewono; Widjiati Widjiati
Majalah Obstetri dan Ginekologi Vol. 27 No. 2 (2019): August
Publisher : Universitas Airlangga

Objectives: To analyze the difference neuronal and glial (astrocytes, oligodendrocyte, microglia) cell count in cerebrum and cerebellum of Rattus norvegicus newborns with 50% food restriction and control group.Materials and Methods: This was an analytical experimental study with single blind randomized post test only control group design using animals subjects Rattus norvegicus. This study was conducted at Animal laboratory, Veterinary Faculty, Universitas Airlangga. Animal subjects were divided into FR50% group and control. Neuron and glial (astrocytes, oligodendrocytes, microglia) counts were analyzed using comparison test, with CI 95%.Results: There was a significant difference in cerebrum and cerebellum neuron cell count between intervention and control group (9.88+3.59 vs 16.88+2.553; p=0.000 and 7.5+1.789 vs 11.44+4.56; p=0.02). There was no difference in cerebrum and cerebellum glial cell count. There was a significant difference in cerebellum astrocyte between intervention and control group (80.94+24.255 vs 59.69+18.77; p=0.02) but no difference in cerebrum. There was a significant difference in cerebrum and cerebellum oligodendrocyte between intervention and control group (14.06+12.195 vs 25.13+8.609; p<0.000 and 13.63+6.712 vs 24.00+8.862; p=0.001), and there were significant difference in cerebrum and cerebellum microglia cell between intervention and control group (5.25+3.435 vs 4.94+3.838; p=0.620 and 8.81+4.119 vs 5.25+1.483; p=0.004).Conclusion: Food Restriction 50% (FR50%) in Rattus norvegicus decreased cerebrum and cerebellum neuron cell and oligodendrocyte count and increased cerebrum and cerebellum microglial count.

The evidence for the influence of musical compositions during pregnancy to the structure and functions of the offsprings’ brain Hermanto Tri Joewono
Majalah Obstetri dan Ginekologi Vol. 28 No. 1 (2020): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V28I12020.44-51

Objective: to compile studies in Surabaya on the effect of Mozart compositions during pregnancy on the number of the offsprings brain neuron, glia, BDNF, apoptotic neurons and, neuronal dendritic density. These series of studies aimed to develop environmental-enrichment model during pregnancy so we can have better brain for the next generation. Better brain means better capacity in processing information, solving the problems, and creating new solutions that depends on the number of neuron, glia, ratio glia/ neuron and synapses. We do believe in the motto of “From Neurons to Nation” Overview: There were 38 studies, in animal models except two in human subjects, all of them with control, prospective, and randomized. The first group consist of analyze the frequency, sequence, time, duration, gestational age, distant, and intensity of Mozart composition. The second group: try to analyze the mechanism and compare with variety of other compositions including other western music(Chopin, Beethoven, Blues, Jazz, Rock) and Indonesian music(Gamelan Jawa, Sunda, Bali, Pop, Religious). The third group: combine with nutrition, reverse sequence, involving cerebrum and cerebellum, and right-left hemisphere. There were no growth restricted, dead, and malformed offsprings in both groups. The BDNF expression, synapsin I expression, the number of neuron, number of glia, and dendritic density of the exposed groups were higher than control. The neuronal apoptotic index were lower in the exposed groupsConclusions: Mozart compositions during pregnancy increased the BDNF, synapsin I, number of neuron, number of glia, dendritic density and, also decreased the neuronal apoptosis in offsprings’ brain

Effects of Folic Acid Intake during Pregnancy whose Mother was Exposed to Cigarette Smoke towards Brain Neurons Apoptosis Index and Quantity of Mice (Mus musculus) Offspring Nyna Puspa Ningrum; Hermanto Tri Joewono; Widjiati Widjiati
Folia Medica Indonesiana Vol. 54 No. 1 (2018): March
Publisher : Faculty of Medicine, Universitas Airlangga

Folic acid contains 5-methyltetrahydrofolate (5-MTHF), one of antioxidants that can be used to inhibit reaction caused by cigarette smoke exposure. Folic acid is able to inhibit the levels of Reactive Oxygen Species (ROS) so as to reduce the occurrence of neuronal apoptosis. The objectives of this study was to determine the effect of folic acid intake during pregnancy whose mother was exposed to cigarette smoke on brain neurons apoptosis index and quantity of mice (Mus musculus) offspring. This study was an experimental laboratory study with posttest-only control group design. The subjects were 24 female mice divided into 4 groups consisting of one control group and three treatment groups. Sampling used simple random sampling, each group consisting of 6 animals. Control group 1 was not given treatment during pregnancy, group 2 was given with folic acid orally on days 0-17 of gestational age as much as 0.06 mg/day/mice. Group 3 was given with cigarette smoke exposure on days 7-17 of gestational age, amounting to 2 cigarettes/day. Group 4 was given with cigarette smoke exposure on days 7-17 of gestational age, amounting to 2 cigarettes/day and folic acid orally on days 0-17 of gestational age as much as 0.06 mg/day/mice. The result showed significant differences in all variables. In neurons apoptosis index, there were significant differences between groups 1 and 3, groups 2 and 3, groups 3 and 4, significant differences in the quantity of neurons between groups 1 and 3, groups 2 and 3, groups 2 and 4. The study concluded that there were significant difference in neural apoptosis index between all groups, and there were also significant differences in the quantity of neurons between all groups.

Maternal Educational Status as One of the Risk Factors Affecting the Incidence of Infants with Low Birth Weight in Dr. M. Soewandhie General Hospital Surabaya Jihanifa Hega Salsabiila; Hermanto Tri Joewono; Sulistiawati Sulistiawati
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 12 No. 1 (2021): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V12I12021.10-13

Introduction: Infants with low birth weight (LBW) was one of the main indicators of the cause of high infant mortality rates (IMR). The causes of IMR and maternal mortality rate (MMR) were determined by factors in maternal condition before and during pregnancy. In 2015, LBW in Surabaya reached 2.58%, namely a number of 1,261 of 48,783 born babies weighed. This study was performed by analyzing the effect of educational status as a risk factor affecting LBW in Dr. M. Soewandhie General Hospital Surabaya. Methods: This study used case control method with a retrospective approach using patient medical records as secondary data. The sample population were mothers who gave birth to infants with birth weight of 1,500 – 4,000 g in Dr. M. Soewandhie General Hospital Surabaya. The number of samples consisted of 80 patients with case and control ratio of 1:1. The sampling technique used was purposive sampling. Data collection techniques used variable data collection sheets taken from secondary data, namely medical records. Data analysis was performed by Chi-Square and Odds Ratio (OR) statistical tests. Results: Based on Chi-Square test, there was a relationship between educational status (p = 0.034) with the incidence of LBW. The results of this study indicated that the educational status of mothers that graduated from elementary school – senior high school was at risk of 9,750 times in delivering LBW. Conclusion: Educational status was the risk factor that had a correlation with LBW.

MATERNAL OBESITY INCREASES RISK OF PREECLAMPSIA AND DIABETES MELLITUS Naura Ega Kahayani; Hermanto Tri Joewono; Rio Wironegoro
Majalah Biomorfologi Vol. 31 No. 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i2.2021.44-48

Background: Obesity in pregnant women has been linked to negative outcomes for both the mother and the fetus. Gestational diabetes, preeclampsia, and postpartum haemorrhage are all threats for mothers during pregnancy. These may also affect labor outcomes because fat accumulation in the pelvis makes obese pregnant women more likely to have a caesarean section. Objective: To analyze the outcome of maternal obesity in pregnancy in 2017. Materials and Methods: This was an analytic cross-sectional, observational study in pregnant women with obesity in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, within the period of January 1st – December 31st 2017 using medical records. Sample size was determined using cross-sectional sample size calculation with the result of n=162. After receiving approval of ethical clearance, medical records were collected and analyzed. The statistical analysis was done using chi-square test. Results: From a total of 162 subjects, most of the patients were 21-34 y/o (56.8%), under graduate (90.7%) and 58% of the subjects worked. Proportion of grade I, II and III were 60.5%, 22.2%, and 17.3%, and 67% suffered from complications such as PE, DM, PE with DM with percentages as follows: 56.2%, 4.9%, and 6.2%. Neonatal complications were preterm 42.6%, macrosomia 4.3%, stillbirth 4.9%, and low Apgar score 48.1%. No association was identified between maternal age and complications in grade I (p=0.764) and grade III (p=0.716). Obesity grades I and III had correlation with complications (p=0.035). Conclusion: No significant association was found between age and complications in grade III obesity, while there was significant correlation between obesity levels (grade I and grade III) and complications.

Faktor yang Memengaruhi Penundaan Kehamilan Pada Pernikahan Remaja Usia 14-19 Tahun Di 2 Kabupaten Provinsi Gorontalo Eka Fitriani Sujitno; Hermanto Tri Joewono; Margarita M Maramis
Jurnal Keperawatan Muhammadiyah 2019: EDISI KHUSUS
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

The incidence of marriage at a young age is till very high in Indonesia. Indinesia is the 37th country with a high prevalence of young marriage in the world and the second highest in ASEAN after Cambodia (UNDESA, 2010). According to BPS (2015), Gorontalo Province is ranked 5th based on the prevalence of marriage of girls aged 15-19 years. The purpose of this study was to analyze the factors that influence the delay of pregnancy in teenage marriages aged 14-19 years. The methodology used is the case control design. Research subjects were married women aged 14-19 years in 2015-2017 in 2 districts Gorontalo province who realize the inclusion criteria. Number of samples for each group of 75 respondents for cases and controls. Statistical analysis was performed by chi square technique and logistic regression analysis method. Results: shows the factors that influence the delay of pregnancy in adolescent marriage are wife's age (p = 0,000, OR = 8,889, 95% CI = 2,887-27,375) and family support (p = 0,000, OR = 28, 95% CI = 7,793- 100,612). The conclusion of this study is that the wife's age and family support have a significant relationship to the delay of pregnancy in adolescent marriage. Disorder towards toddlers by 2,5 times.

Faktor yang Memengaruhi Kehamilan Sebelum Menikah Pada Remaja Di Empat Puskesmas Kabupaten Sikka Tahun 2017 Agnes Krisylva; Hermanto Tri Joewono; Margarita M Maramis
Jurnal Keperawatan Muhammadiyah 2019: EDISI KHUSUS
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

Pre-marital pregnancy in adolescents contains very complicated and complex issues, especially for those who are directly involved in it. Pre marital pregnancy in adolescents in Sikka District in 2017 was 191 people (47%) of the total number of teenagers who were pregnant. Many factors influence pregnancy before marriage in adolescents including age, order of children, education, parents job, family income, parental marital status, parenting, culture and religiosity.The purpose of this study was to analyze the factors that influence the occurrence of pregnancy before marriage in adolescents in four Community Health Centers of Sikka District . Methods: An analytic observational study with a case control study design. The sampling technique used is Quota Sampling. Sampling in four Community Health Centers with a high percentage of pregnancy before marriage. The control group was taken with the same age match, namely age 10-19 years in the same area, each of 90 teenagers were pregnant before marriage (case) and teenagers were pregnant after marriage (control).Result: The multiple logistic regression test showed that together there was a significant relationship between parenting of the parents (p <0.05, OR = 14.107), parental marital status (p <0.05, OR = 4.359) and religiosity (p <0.05 , OR = 2,651) with pre-marital pregnancy in adolescents. Age, order of children, education, parental work, parents job, income and culture are not related to pre-marital pregnancy in adolescents in four Community Health Centers of Sikka District.Conclusion: Bad parenting factors play the most important role in the occurrence of pregnancy before marriage in adolescents in four Community Health Centers of in addition to the factors of parental marital status and religiosity.

Promosi Kesehatan Ibu Hamil di Masa Pandemi COVID-19 Menggunakan Pendekatan Punyuluhan Digital Individual di Surabaya Hermanto Tri Joewono; Brahmana Askandar Tjokroprawiro; Ernawati Ernawati; Nareswari Imanadha Cininta Marcianora; Okta Margarita Susiana; Yasyviena Za’ima Elnabila; Nabeel Usama Okbah; Sabrina Kemala Hapsari; Hafiza Amadhin Rusti; Achmad Zam Zam Aghasy
Jurnal Abdi Masyarakat Indonesia Vol 1 No 2 (2021): JAMSI - November 2021
Publisher : CV Firmos

Wanita hamil merupakan populasi yang rentan terdampak penyakit COVID-19. Kehamilan dengan COVID-19 memiliki peningkatan risiko untuk terjadi penyulit seperti persalinan preterm. Data per Januari 2021 di RSUD dr. Soetomo Surabaya, menunjukkan kasus kehamilan dengan COVID-19 telah mencapai 140 kasus, di mana 85% adalah warga Surabaya. Tujuan kegiatan ini adalah untuk mengetahui tingkat pengetahun masyarakat terkait COVID-19 pada kehamilan di Kota Surabaya. Metode yang digunakan dalam kegiatan ini adalah penyuluhan digital menggunakan Whatsapp secara individual dilengkapi video kepada kelompok ibu hamil di wilayah kerja Puskesmas Mulyorejo Kota Surabaya. Video berisi materi mengenai kesehatan ibu hamil dan janin di masa pandemi COVID-19, protokol Kesehatan untuk ibu hamil, serta cara deteksi dini COVID-19 pada kehamilan dan kegawatannya. Selanjutnya dilakukan intervensi secara daring dengan peserta mengisi google form pre-test dan post-test sebagai indikator peningkatan wawasan peserta. Hasil dari kegiatan pelaksanaan ini adalah terdapat pengaruh peningkatan pengetahuan ibu hamil mengenai pentingnya menjaga kesehatan kehamilan di masa pandemi COVID-19.

Co-Authors Abdullah, Aya Ali Achmad Zam Zam Aghasy Agnes Krisylva Agus Sulistyono Agustina Hidayati Agustina Mar'atus Sholichah Ahmed, Samar A. A. Al-Qadhi, Tasnim Mohammed Aldika Akbar, Muhammad Ilham Ali Madinah Ali Medina Ali Medina Ali, Lamia A. S. Almothana, Hebah H. M. Alselwi, Sarah A. D. Alsoufi, Fardous G. Amila, Ukhti Mukminah ilmi Amishinta, Ancha Ayu Amishinta, Ancha Ayu Ancha Ayu Amishinta Andita Hapsari Andriani, Linda Aprilawati, Dwi Askandar Tjokroprawiro Ayu Putri Yani Binta Dwi Novitasari Chandra, Cecilia Felicia Dedi Kuswandi Dessy Hidayati Fajrin Diana Estu Rumahastuti Dwi Budi Santoso Dwi Nurdi Puspita Sari Dwi Puji Wijayanti Ecccita Raheestyningtyas Eka Fitriani Sujitno Eka Nasrur Maulana Eko Budi Koendhori, Eko Budi Ernawati Ernawati Esti Nugraheny Fajrin, Dessy Hidayati Fitria Desky Frisilia Octaviana Yolanda Gatut Hardianto, Gatut Hafiza Amadhin Rusti Hajj, Suha Ali Al Harry Mangasi Binsar Panjaitan Hasan, Helmia Henky Mohammad Masteryanto HERAWATI, LILIK Herlina Alvianti N Herlina Puji Angesti Herman, Sriyana Heryana, Achmad Yuniari Jihanifa Hega Salsabiila Jimmy Yanuar Anas Khanisyah Erza Gumilar Khasanah, Rima Nur Laksana, Muhammad Ardian Cahya Maramis, Margarita M. Maria Inge Lusida Martono Tri Utomo Mikra Latisfian Mikra Latisfian Mikra Latisfian Mohammed, Haitham T. S. Muhammad Adrianes Bachnas Muhammad Miftahussurur Muhdi, Nalini Nabeel Usama Okbah Nareswari Imanadha Cininta Marcianora Naura Ega Kahayani Nur Cholila Nur Laila Faizah Nurvy Alief Aidillah Nyna Puspa Ningrum Okta Margarita Susiana Pamarga Priyambodo Pitria Permatasari Pudji Lestari PUNGKY MULAWARDHANA, PUNGKY Rejeki, Purwo Sri Rio Wironegoro Risa Etika, Risa Sabrina Kemala Hapsari Sakina Samsriyaningsih Handayani Siti Nur Kholifah Siti Nur Kholifah Siti Nur Kholifah Sofiyanti Miftakhurohmah Sonea Venugopal Sulistiawati Sulistiawati Sulistiawati Sulistiawati Tanadi, Melina Rosita Thabet, Habib Thabit, Riyadh A. S. Ucik Nurul Hidayati Ukhti Mukminah ilmi Amila Ummah, Fithriyah Cholifatul Wardhana, Manggala Pasca Wati, Yunita Kholilaili Saras Widati Fatmaningrum Widjiati Widjiati w Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati Widjiati, Widjiati Widjiati, DR Widjiati, DR Windhu Purnomo Yaner, Nurul Ramadhani Yanti Yanti Yasyviena Za’ima Elnabila Yulia Putri Permatasari Zumroh Hasanah

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