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Journal : Jurnal Medik Veteriner

Efektivitas Sugar Dressing (100% Gula) dalam Meningkatkan Kepadatan Kolagen pada Proses Penyembuhan Luka Bakar Buatan pada Kulit Tikus Putih (Rattus norvegicus) Jantan Ivanalee, Angela Swasti; Yudaniayanti, Ira Sari; Yunita, Maya Nurwartanti; Triakoso, Nusdianto; Hamid, Iwan Sahrial; Saputro, Amung Logam
Jurnal Medik Veteriner Vol. 1 No. 3 (2018): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (559.656 KB) | DOI: 10.20473/jmv.vol1.iss3.2018.134-141

Abstract

Luka bakar merupakan hilangnya atau rusaknya keutuhan kulit akibat paparan suhu atau pH, zat kimia, gesekan, trauma tekanan dan radiasi. Proses penyembuhan luka tidak lepas dari peran kolagen. Sintesis kolagen dapat dipromosikan melalui pemberian gula (sugar dressing). Tujuan penelitian ini adalah mengetahui efektivitas sugar dressing untuk meningkatan kepadatan kolagen dalam proses penyembuhan luka bakar buatan pada kulit tikus putih (Rattus norvegicus) jantan. Dua puluh ekor tikus putih (Rattus norvegicus) jantan dibagi menjadi lima kelompok dengan jumlah empat ekor tiap kelompok. Kelompok K- (kontol negatif) tidak diberi perlukaan. Kelompok K+ (kontrol positif) di beri perlukaan kemudian hanya diberi bilasan NaCl fisiologis. Kelompok P1 (Bioplacenton®) diberi perlukaan dengan pengobatan Bioplacenton®. Kelompok P2 (sugar dressing) diberi perlukaan dengan pengobatan gula dan P3 (madu) menggunakan madu sebagai obat. Perawatan diberikan setiap hari sekali selama empat belas hari. Hasil uji nonparametrik Kruskal-Wallis menunjukkan perbedaan yang signifikan (p<0,05) dan dilanjutkan dengan uji beda Mann-Whitney. Kepadatan kolagen kelompok P1, P2, dan P3 tidak berbeda secara nyata (p>0,05), tetapi berbeda nyata dengan kelompok K- dan K+. Kesimpulan dari penelitian ini adalah sugar dressing efektif untuk meningkatkan kepadatan kolagen pada proses penyembuhan luka bakar.
Efektivitas Ekstrak Daun Afrika (Vernonia amygdalina) Secara Topikal Untuk Reepitelisasi Penyembuhan Luka Insisi Pada Tikus Putih (Rattus novergicus) Putrianirma, Rizki; Triakoso, Nusdianto; Yunita, Maya Nurwartanti; Yudaniayanti, Ira Sari; Hamid, Iwan Sahrial
Jurnal Medik Veteriner Vol. 2 No. 1 (2019): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (661.601 KB) | DOI: 10.20473/jmv.vol2.iss1.2019.30-35

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh dan hubungan konsentrasi pemberian ekstrak daun afrika (Vernonia amygdalina) secara topikal terhadap efektivitas penyembuhan luka dan reepitelisasi penyembuhan luka insisi pada tikus putih. 20 tikus putih jantan di kelompokkan secara acak dibagi dalam 5 kelompok perlakuan yaitu P0 (vaseline + adeps lanae), P1 (povidone iodine), P2 (salep ekstrak daun afrika 16,8 %), P3 (salep ekstrak daun afrika 28 %), dan P4 (salep ekstrak daun afrika 39,20 %). Penelitian ini dilakukan selama 14 hari dengan mengukur dengan skor reepitelisasi pada sediaan histopatologi kulit luka insisi yang telah diberi perlakuan. Hasil penelitian tidak menunjukkan perbedaan yang nyata antara kontrol dengan perlakuan (p>0,05). Perlakuan dengan ekstrak daun afrika (Vernonia amygdalina) tidak menunjukkan reepitelisasi yang berbeda dengan perlakuan kontrol.
Pengaruh Ekstrak Daun Sukun (Artocarpus altilis) Terhadap Kepadatan Kolagen dalam Proses Penyembuhan Luka Eksisi Tikus Putih (Rattus norvegicus) Cahya, Rizka Wulan; Yudaniayanti, Ira Sari; Wibawati, Prima Ayu; Yunita, Maya Nurwartanti; Triakoso, Nusdianto; Saputro, Amung Logam
Jurnal Medik Veteriner Vol. 3 No. 1 (2020): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (679.313 KB) | DOI: 10.20473/jmv.vol3.iss1.2020.25-30

Abstract

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh ekstrak daun sukun (Artocarpus altilis) terhadap kepadatan serabut kolagen dalam penyembuhan luka eksisi pada tikus putih (Rattus norvegicus). Dua puluh ekor tikus jantan dibagi secara acak menjadi lima kelompok, terdapat kontrol negatif (K-) yang diberikan basis salep, kontrol positif (K+) yang diberikan povidone iodine 10%, kelompok perlakuan (P1, P2, P3) yang diberikan salep ekstrak daun sukun 6,25%; 12,5%; dan 25%. Terapi diberikan sekali sehari selama empat belas hari. Hasil uji nonparametrik Kruskal-Wallis menunjukkan perbedaan nyata (p<0,05) dan dilanjutkan dengan uji Mann-Whitney. kelompok kepadatan kolagen P1, P2, dan P3 tidak berbeda nyata (p>0,05), tetapi berbeda nyata dengan kelompok K- dan K+. Kesimpulan dari penelitian ini adalah ekstrak daun sukun efektif untuk meningkatkan kepadatan kolagen dalam proses penyembuhan luka eksisi.
Efektivitas Krim Ekstrak Buah Naga Merah (Hylocereus polyrhizus) dalam Meningkatkan Jumlah Sel Fibroblas Luka Bakar Derajat II pada Tikus Putih (Rattus norvegicus) Rahmadhani, Nurmitasari; Yudaniayanti, Ira Sari; Saputro, Amung Logam; Triakoso, Nusdianto; Wibawati, Prima Ayu; Yudhana, Aditya
Jurnal Medik Veteriner Vol. 3 No. 1 (2020): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (876.884 KB) | DOI: 10.20473/jmv.vol3.iss1.2020.65-75

Abstract

Tujuan penelitian ini adalah untuk mengetahui efektivitas krim ekstrak buah naga merah (Hylocereus polyrhizus) dalam meningkatkan jumlah sel fibroblas luka bakar derajat II pada tikus putih (Rattus novegicus). Dua puluh ekor tikus putih (Rattus novegicus) jantan dibagi menjadi lima kelompok perlakuan dengan jumlah empat ulangan setiap kelompok. Semua tikus tersebut diinduksi dengan luka bakar derajat II. Kelompok kontrol negatif (K-) diterapi dengan basis krim minyak dalam air, Kelompok kontrol positif (K+) diterapi dengan Bioplacenton®, kelompok perlakuan diterapi dengan krim ekstrak buah naga merah (Hylocereus polyrhizus) dengan konsentrasi P1 7.5%, P2 15%, dan P3 30%. Terapi diberikan dua kali dalam sehari selama 10 hari. Hasil uji Kolmogorov-Smirnov menunjukkan data terdistribusi normal (p>0.05) dilanjutkan dengan uji Oneway ANOVA yang menunjukkan adanya perbedaan nyata dari tiap kelompok perlakuan (p<0.05) dan dilanjutkan dengan uji Post-Hoc LSD. Rata-rata jumlah fibroblas setiap kelompok perlakuan menunjukkan bahwa kelompok K- dan K+ berbeda nyata dengan kelompok P1, P2 dan P3. Jumlah sel fibroblas terbanyak didapati pada kelompok P2. Kesimpulan dari penelitian yang telah dilakukan adalah krim ekstrak buah naga merah (Hylocereus polyrhizus) dapat meningkatkan jumlah sel fibroblas luka bakar derajat II pada tikus putih (Rattus norvegicus).
Pengaruh Kitosan Udang Secara Topikal Terhadap Kepadatan Kolagen dalam Penyembuhan Luka Eksisi pada Tikus Putih Prastika, Dinda Dwi; Setiawan, Boedi; Saputro, Amung Logam; Yudaniayanti, Ira Sari; Wibawati, Prima Ayu
Jurnal Medik Veteriner Vol. 3 No. 1 (2020): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (839.412 KB) | DOI: 10.20473/jmv.vol3.iss1.2020.101-107

Abstract

Luka eksisi adalah luka yang permukaan kulit dan lapisan bawahnya akan terpotong sampai kedalaman yang bervariasi dapat terjadi secara sengaja atau tidak sengaja. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh chitosan kulit udang terhadap kepadatan kolagen dalam proses penyembuhan luka eksisi pada tikus putih. Sebanyak dua puluh ekor tikus putih (Rattus norvegicus) jantan dibagi ke dalam lima kelompok perlakuan yaitu K- luka eksisi dengan pemberian basis salep, K+ (luka eksisi+10% povidone iodine), P1 (luka eksisi+salep chitosan kulit udang 1.5%), P2 (luka eksisi+udang salep kulit kitosan 2.5%), dan P3 (luka eksisi+kitosan kulit udang 5%). Hasil perhitungan persentase kepadatan kolagen dianalisis oleh Kruskal-Wallis yang menunjukkan perbedaan signifikan (p<0.05) dan dilanjutkan dengan uji Mann-Whitney U. Kelompok K+, K- dan P1 memiliki perbedaan signifikan dalam kepadatan kolagen pada P2, dan kelompok P3 (p<0.05). Kesimpulan dari penelitian ini kitosan berpengaruh terhadap kepadatan kolagen dengan dosis 5%.
An Evaluation of Nutritional Factors on The Prevalence of Urolithiasis in Cats at The Veterinary Teaching Hospital, Universitas Airlangga During 2017-2019 Mahdi, Daffa Amanul; Sardjana, I Komang Wiarsa; Yudaniayanti, Ira Sari; Estoepangestie, Agnes Theresia Soelih; Triakoso, Nusdianto; Primarizky, Hardany
Jurnal Medik Veteriner Vol. 6 No. 2 (2023): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss2.2023.180-184

Abstract

Stones, or uroliths, in the urinary tract cause a disorder called urolithiasis. Patients with urolithiasis may experience blockage and possibly mortality; therefore, prompt treatment is imperative. This study aimed to investigate the prevalence of urolithiasis and its nutritional association in cats treated at the Veterinary Teaching Hospital, Universitas Airlangga during 2017-2019. Data was collected from the secondary resource from the medical report and the factor of feed nutrition involved fiber, protein, fat, and moisture. Data was analyzed using logistic regression to determine the influence of nutrition on the prevalence of urolithiasis in cats in the respective period. The findings indicated that in 2017, urolithiasis prevalence was 0,96%; in 2018, it was 5,55%; and in 2019, it was 0,91%. Meanwhile, it was revealed that the prevalence of urolithiasis was not significantly impacted by feed nutritional variables.
The Effect of Apis dorsata Honey Treatment on Calcium Levels of Mandibular Bone in Ovariohysterectomized Wistar Rats Rohmah, Siti Nur; Yudaniayanti, Ira Sari; Primarizky, Hardany; Hastutiek, Poedji
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.1-7

Abstract

This study aimed to evaluate the efficacy of Apis dorsata honey on calcium levels in the mandibular bone of Wistar rats after ovariohysterectomy as an animal osteoporosis model for treating cases of osteoporosis. This study used 20 female rats, which were divided into five treatment groups with four replications. SHAM was the negative control group; OH was the ovariohysterectomized group without treatment as a positive control; the AD1, AD2, and AD3 groups were ovariohysterectomized rats with A. dorsata honey at doses of 1 g/kg bw, 2 g/kg bw, and 4 g/kg bw for 84 days. After 84 days of treatment, the left mandibular bones of the rats were collected, weighed, and stored in 10% neutral buffered formalin. Calcium levels were calculated using proximate analysis. The results showed a decrease in bone calcium levels in the ovariohysterectomy group, the highest results were in the SHAM group, and the lowest results were in the AD3 group. It can be concluded that the administration of A. dorsata honey could not maintain the calcium level of the mandibular bone in the ovariohysterectomized Wistar rats.
The Efficacy of Madeira Vine Leaf Extract Combined with Turmeric Rhizome Extract Gel Topically on Second-Degree Burn Wound in Albino Rats Hisyam, Mirza Atikah Madarina; Yuniarti, Wiwik Misaco; Theresia, Sis Wisnuarti; Yudaniayanti, Ira Sari; Lukiswanto, Bambang Sektiari; Sudjarwo, Sri Agus; Widiyatno, Thomas Valentinus
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.91-98

Abstract

Burns is now considered one of the most destructive forms of trauma affecting humans and animals. This study aimed to determine the effect of Madeira vine leaf extract combined with 2% Turmeric rhizome extract (MVLTR) gel administered topically on second-degree burn wound in albino rats based on the number of fibroblasts. A total of 25 male rats weighed 200–300 grams were divided into five groups i.e. (C-) was normal skin, (C+) was burn and treated using 1% silver sulfadiazine, (T1) was burn and treated using 1.25% MVLTR gel, (T2) was burn and treated using 2.5% MVLTR gel, and (T3) was burn and treated using 5% MVLTR gel. The burn wound was performed on the right gluteus of rats, and the therapy was applied twice a day topically, starting after the burn wounds were made. Skin samples were collected on day 15. The histopathological examination was performed by counting fibroblast cells and then analyzed using One-way ANOVA, continued with the Duncan test. Based on the results showed that the C- group was significantly different compared to C+, T1, T2, and T3 groups. C+ had a significant difference with the T1 and T3 groups, meanwhile not significantly different from the T2 group. T2 was not significantly different from the C+ and T3 groups. In conclusion, MVLTR gel at 5% concentration has the potential to be an effective treatment for second-degree burns, as indicated by the increased number of fibroblasts.
Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats Panggabean, Rosenna Tiara; Sudjarwo, Sri Agus; Ma'ruf, Anwar; Widiyatno, Thomas Valentinus; Yudaniayanti, Ira Sari; Kurnijasanti, Rochmah; Khairullah, Aswin Rafif
Jurnal Medik Veteriner Vol. 6 No. 3 (2023): Special Issue: International Conference on Veterinary Medicine and Health Scien
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol6.iss3.2023.107-115

Abstract

Burns not only damage skin locally but generally affect the body system and have been related as the secondary cause of death. Burns can be effectively treated with a topical drug to prevent chronic inflammation. Burn wound healing is really important for ensuring overall health and well-being. This study aimed to determine the effect of Sauropus androgynous leaves extract gel on the number of fibroblasts, fibrocytes, and collagen density on burn wound healing in albino rats. A total of 50 male albino rats were randomly divided into five groups i.e. (C-) was normal skin, (C+) was skin burn treated with placebo, (T1) was skin burn treated with 2.5% of S. androgynous leaves extract gel, (T2) was skin burn treated with 5% of S. androgynous leaves extract gel, and (T3) was skin burn treated with 10% of S. androgynous leaves extract the gel. The amount of 25 albino rats' skin samples were collected on the 8th day, and the remaining samples were collected on the 15th day. The results showed that 10% of S. androgynous leaves extract gel improved faster, as indicated by the increased number of fibroblasts, fibrocytes, and collagen density. This study can be concluded that 10% of S. androgynous leaves extract gel was the effective dosage to increase the number of fibroblasts, fibrocytes, and collagen density in burn wound healing.
Strategic Infectious Diseases in Beef Cattle in Balongpanggang during 2023 Yuniarti, Wiwik Misaco; Lukiswanto, Bambang Sektiari; Setiawan, Boedi; Yudaniayanti, Ira Sari; Triakoso, Nusdianto; Hisyam, Mirza Atikah Madarina; Susanti, Lina; Niken Hastuti, Apriliwiyani; Sudjono, Budi Santoso
Jurnal Medik Veteriner Vol. 7 No. 2 (2024): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol7.iss2.2024.362-369

Abstract

Strategic infectious animal diseases have a great impact on the national economy as they may cause great economic loss, public anxiety, and high mortality. In Indonesia, among the diseases considered as strategic infectious animal diseases is foot and mouth disease (FMD). This study reported the incidence of strategic infectious animal diseases in Balongpanggang district during 2023. Throughout 2023, FMD only accounted for 4% of the total diseases of the year and was the only strategic infectious animal disease reported that year. Meanwhile, bovine ephemeral fever (BEF) incidence reached 57% (876/1546) of the total diseases in beef cattle in 2023. In addition to BEF, official veterinary services reported a total case of 1546 throughout 2023 that comprises; diarrhea (99), limping (24), helminthiasis (91), ectoparasite (11), hematochezia (3), wound (3), mastitis (4), allergy (1), dystocia (28), vaginal prolapse (11), dermatitis (45), enteritis (27), tympani (11), scabiosis (122), arthritis (67), ophthalmic problem (11), endometritis (1), uterine retention (13), indigestion (2), pneumonia (21), hypoglycemia (5), abscess (21), ovariohysterectomy (1), orchitis (1), intoxication (1), and papilloma (1). In conclusion, the only strategic infectious animal disease reported in 2023 in Balongpanggang was FMD with the incidence as high as 3% as compared to the non-strategic infectious animal diseases, BEF, which reached 54% of the total cases during 2023.
Co-Authors A'la, Rofiqul Abdul Samik, Abdul Adikara, Yuanara Augusta Rahmat Al arif, Mohammad Anam Aswin, Ahmad Bambang Sektiari Lukiswanto Billa, Lutfiah Annisa Boedi Setiawan Cahya, Rizka Wulan Diyantoro Diyantoro, Diyantoro Eduardus Bimo Aksono Herupradoto Eka Pramyrtha Hestianah, Eka Pramyrtha Estoepangestie, Agnes Theresia Soelih Fatin Fadhilah Hasib Fedik Abdul Rantam Fidyah Fitrawati, Fidyah Hadiah Fitriyah Haeriah Hani Plumeriastuti Helen Susilowati, Helen Hidanah, Sri Hisyam, Mirza Atikah Madarina Immelda, Kicky Hanis Ivanalee, Angela Swasti Iwan Sahrial Hamid Kadek Rachmawati Karo-karo, Desniwaty Khairullah, Aswin Rafif Kuncorojakti, Suryo Kusnoto Kusnoto, Kusnoto LINA SUSANTI Lucia Tri Suwanti, Lucia Tri Ma'ruf, Anwar Mafruchati, Maslichah Mahdi, Daffa Amanul Mardatillah, Meidy Miarsono, Sigit Mirni Lamid Niken Hastuti, Apriliwiyani Nusdianto Triakoso Panggabean, Rosenna Tiara Poedji Hastutiek Prastika, Dinda Dwi Primarizky, Hardany Putri, Desak Ketut Sekar Cempaka Putrianirma, Rizki R.T.S Adikara, R.T.S Adikara Rahmadhani, Nurmitasari Rahmahani, Jola Rahmawati, Kadek Ratna Damayanti Rochmah Kurnijasanti Rodprasert, Watchareewan Rohmah, Siti Nur Rosyada, Zulfi Nur Amrina Sabdoningrum, Emy Koestanti Santoso, Kuncoro P. Saputro, Amung Logam Sardjana, I Komang Wiarsa Soeharsono Soeharsono Soeharsono Sofyan, Miyayu Soneta Sri Mumpuni Sudjono, Budi Santoso Suherni Susilowati Sukmanadi, M Susilawati, Helen Suwarno Suzanita Utama Theresia, Sis Wisnuarti Wahyudi, Nurul Tri Warsito, Sunaryo Hadi Wibawati, Prima Ayu Widiyatno, Thomas Valentinus Widya Paramita Lokapirnasari Wijaya, Andi Yasmin Wiwik Misaco Yuniarti Wurlina, W Yudhana, Aditya Yunita, Maya Nurwartanti Yunus, Muchammad