Article Per Year (5 Year)
p-Index From 2021 - 2026
4.374
P-Index
This Author published in this journals
All Journal JURNAL GIZI INDONESIA Majalah Kedokteran Bandung The Indonesian Biomedical Journal Public Health of Indonesia Media Ilmu Kesehatan Jurnal Kesehatan Jurnal Analis Medika Biosains (JAMBS) Abdi Dosen : Jurnal Pengabdian Pada Masyarakat PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Prima Medika Sains Jurnal Aisyah : Jurnal Ilmu Kesehatan AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Jurnal Kesehatan Tambusai International Journal of Islamic Education, Research and Multiculturalism (IJIERM) JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Buletin Kedokteran dan Kesehatan Prima International Journal of Health and Pharmaceutical (IJHP)
Widya Yanti Sihotang
Universitas Prima Indonesia
Religion Aerospace Engineering Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 33 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 33 Documents
Search

 1   2   3   4 
Nephroprotective Effects of Sunkist Peel Ethanol Extract on Diabetic Nephropathy Mutia, Maya Sari; Ginting, Chrismis Novalinda; Yulizal, OK; Suhartomi, Suhartomi; Sihotang, Widya Yanti
Majalah Kedokteran Bandung Vol 56, No 3 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3496

Abstract

The most common long-term diabetic complication is diabetic nephropathy which, in most cases, falls into the End-Stage Kidney Disease. Numerous studies on the nephroprotective effects of citrus fruit have been conducted recently. This study was performed to investigate the phytochemical properties of Sunkist peel ethanol extract and their possible effects on improving diabetic nephropathy. To get the extract, the Sunkist peels were macerated and the extract was analyzed by GC-MS. An in vivo assay of five different groups of 25 male Wistar rats was then performed using the extracts. The groups included control, standard, 500 mg/kg extract, 750 mg/kg extract, and 1,500 mg/kg BW extract. All rats were sacrificed after 28 days of treatment and VEGF level serum and kidney histology analysis were performed. The VEGF data were first analyzed descriptively, followed by one-way ANOVA or Kruskal-Wallis test based on the data distribution. Meanwhile, the kidney histology was observed and narratively described. Results showed that the Sunkist peel ethanol extract has a potential effect to suppress the VEGF level (p-value < 0.05). The extract at the highest dose revealed the mildest pathology damage in the form of tubular structure degeneration without any glomerular damage. This study indicates that Sunkist peel extract has nephroprotective effects from its various phytochemical compounds that work as antioxidants and anti-inflammation.
Effects Of Combination Sunkist and Lime Peel Nanoparticle Granules on Oxidative Stress and Heart Histopathology in Diabetes Rats Sihotang, Widya Yanti; Mutia, Maya Sari; Chairul, Muhammad; Irwanda, Desi Danilah; Nabila, Putri; Hamsi, Ulpah Zahara
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 10 No.2 November 2024
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v10i2.18973

Abstract

Diabetes mellitus and its consequences are significantly influenced by oxidative stress. Sunkist and lime oranges are a nutritional powerhouse, offering a range of health benefits due to their high content of antioxidants, vitamins, minerals, and fiber. Key compounds like anthocyanins, flavanones, and hydroxycinnamic acid contribute to their potential positive impact to reduce oxidative stress. Therefore, the effect of nanoparticle granules combination of sunkist orange peel and lime peel was investigated on diabetic rats. Twenty male Wistar rats were randomly distributed:  Group 1 as control group given distilled water, Group 2 as DM group with alloxan, Group 3 with DM + NGSLP 100mg / kgBW, Group 4 with DM + NGSLP 200mg / kgBW. Rats with diabetes were treated by intraperitoneal injection with 100 mg/kg alloxan. NGSLP treatment was given for 14 days to each treatment group. At the end, the blood and heart tissue were collected and used to determine the GPx enzyme, SOD, MDA, CAT and histological evaluation. Diabetes induction increased the level of MDA and decreased after treated with NGSLP. In diabetic rats treated with NGSLP showed an increase in SOD, GPX and CAT in blood. Histopathological findings of heart tissue showed the protective effect of NGSLP in rats with diabetic. This study revealed that NGSLP has antioxidant effects in the blood and heart of alloxan-induced diabetic rats.
Analysis of factors influencing smoker behavior in designated non-smoking zone on campus Leonardi, Felix; Trirasetya, Mutiara Ulfa; Suhartomi, Suhartomi; Sihotang, Widya Yanti; Edison, Rizki Edmi
MEDIA ILMU KESEHATAN Vol 13 No 2 (2024): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v13i2.1365

Abstract

Background: The GATS research findings indicate that tobacco use in Indonesia is the highest worldwide among teenagers, with a percentage of 34.8% consumed by individuals aged 15 and above. Tobacco companies leverage this legality to market cigarettes widely to students, including university students. Smoke-free areas are government efforts to prevent smoking on campuses.Objective: To identify determinant factors affecting non-smoking behavior among smokers in smoke-free campus areas.Methods: This research study is descriptive quantitative with a cross-sectional design. It used a purposive sampling technique with criteria of 74 male smoker students from the Faculty of Medicine and Dentistry at Universitas Prima Indonesia and was analyzed using a chi-square test.Results: The chi-square test analysis results indicated an effect between knowledge and attitude on non-smoking behavior in smoke-free campus areas with a P-value of 0.001.Conclusion: The research findings found that knowledge and attitude are determinant factors of non-smoking behavior among smokers in smoke-free campus areas.
Incidence and risk factors of asbestosis among workers in industrial sector: literatur review Sihotang, Widya Yanti; Wicaksana, Praja Dwi; Hakim, Mia Amara; Simangunsong, Pahala Maringan J.; Manalu, Putranto; Siagian, Masryna
MEDIA ILMU KESEHATAN Vol 13 No 3 (2024): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v13i3.1387

Abstract

Background: The industrial sector is a vulnerable place for diseases, especially lung diseases such as asbestosis. Continuous exposure of workers to asbestos has caused the incidence rate to increase over time.Objective: This review aimed to explore the factors influencing the increased incidence of asbestosis in workers in the industrial sectoreMethods: The investigation involved analyzing the results of 17 relevant previous studies using qualitative analysis procedures, variables, themes and factors were extracted from the studies.Results: The analysis revealed eight main categories: age, gender, occupation, industry type, length of exposure, education, income and smoking history. Age, gender and length of exposure were found to be the most important risk factors for asbestosis in workers at an average age of 54 years in men who had been exposed for 21 years.Conclusion: In conclusion, with the increasing incidence of asbestosis from past exposure, this study is needed as an evaluation and consideration in reducing asbestosis in workers.
Effectiveness of Smoke-Free Campus Implementation on Smoking Behavior Control Trirasetya, Mutiara Ulfa; Leonardi, Felix; Suhartomi, Suhartomi; Sihotang, Widya Yanti; Edison, Rizki Edmi
Jurnal Kesehatan Vol 15 No 2 (2024): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v15i2.4538

Abstract

The tobacco industry is a significant obstacle in the effort to control smoking behavior, especially since they are allowed to promote their products to the public, including students. To address this issue, the Ministry of Health developed a smoke-free zone that may be implemented in universities to reduce smoking rates among adolescents. To know the effectiveness of implementing a smoke-free campus policy on smoking behavior control at Universitas Prima Indonesia by assessing aspects of student knowledge and compliance levels. This research is a descriptive quantitative study with a cross-sectional design and uses purposive sampling techniques with the criteria of active smoker students, 74 people in the medical study program of the Faculty of Medicine, Dentistry, and Health Sciences at Universitas Prima Indonesia. Data was obtained in February-April by distributing questionnaires directly to student smokers. The results showed that smoking behavior control among students increased in 50 (67.6%) out of 74 respondents. This is supported by the relationship between the level of knowledge and students' attitudes toward smoking behavior control in the smoke-free campus area, as indicated by a p-value<0.05 (0.005<0.05 and 0.001<0.05). This study found that students’ knowledge and attitudes towards smoke-free campus areas are important aspects influencing the effectiveness of the smoke-free campus policy in controlling smoking behavior.
Correlation Study on Personal Factors of General and Specialist Dentists Regarding Emergency Management of Traumatic Dental Injuries Adrisya Lubis, Putri Anggie; Girsang, Ermi; Sihotang, Widya Yanti
Jurnal Kesehatan Vol 15 No 2 (2024): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v15i2.4495

Abstract

Traumatic dental injuries are increasingly recognized as a significant dental health issue, particularly among children and adolescents. These injuries commonly result from falls, motorbike accidents, sports injuries, or violence. Both general dentists and specialists are responsible for providing emergency care for these injuries, making it essential for them to have sufficient knowledge and experience in managing such cases. This study aims to assess the personal factors influencing the emergency management of traumatic dental injuries among general dentists and specialists in Medan City. A quantitative, cross-sectional design was used, involving a total sample of 300 general and specialist dentists. Data analysis included univariate, bivariate, and multivariate methods. The results showed a significant correlation between knowledge, perception, experience, and work length in managing traumatic dental injuries (p<0.00). However, no correlation was found between age and gender with the ability to manage these injuries (p>0.00). Among the variables, knowledge was identified as the most influential factor. The study concludes that while knowledge, perception, experience, and work duration play a critical role in emergency management, age and gender do not. It is recommended that dentists in Medan continuously enhance their knowledge in this area to ensure effective treatment, reduce patient anxiety, and improve patient satisfaction.
Factors influencing glycaemic control behaviours among individuals with type 2 diabetes mellitus at Royal Prima Hospital, Medan Rafika, Nazla Ghina; Hulu, Victor Trismanjaya; Sihotang, Widya Yanti
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6787

Abstract

Elevated blood glucose levels are indicative of a chronic metabolic disorder known as type 2 diabetes mellitus (T2DM), which necessitates long-term management through effective glycaemic control. Poor glycaemic control behaviours can elevate the risk of severe complications, diminish quality of life, and increase economic burden. This study aimed to analyse the determinants of glycaemic control behaviours in individuals with T2DM at Royal Prima Hospital Medan. A quantitative design employing a cross-sectional method was utilised. The study population comprised all patients with T2DM registered at Royal Prima Hospital Medan. A sample of 182 participants was recruited using consecutive sampling. Data were collected via questionnaires and secondary data from patient medical records. Data analysis included univariate analysis, chi-square tests, and logistic regression for bivariate analysis. The findings of this study demonstrated a significant association between medication adherence and glycaemic control behaviours in individuals with T2DM.
Impact of high glycaemic index food consumption in patients with type 2 diabetes mellitus: A narrative review Haris, Muhammad Akbar; Naufal, Naufal; Hulu, Victor Trismanjaya; Sihotang, Widya Yanti
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6790

Abstract

Consumption of foods with a high glycaemic index (GI) in patients with type 2 diabetes mellitus (T2DM) can negatively impact their glycaemic control. High-GI foods typically induce a rapid increase in blood glucose levels. This research aimed to identify the impact of high glycaemic index food consumption in individuals with T2DM. A narrative review methodology was employed. The inclusion criteria for this study were articles published in indexed journal databases (Google Scholar, ScienceDirect, Scopus Journal, PubMed, ProQuest) written in English, with cross-sectional and experimental designs. Nine articles published between 2008 and 2025 met the inclusion criteria. The findings of this review underscore the importance of understanding glycaemic index food consumption in patients with T2DM. Integrating low-GI foods into the diet of individuals with T2DM may represent a practical strategy for improving metabolic control and reducing the risk of hyperglycaemia. Improved glycaemic control, such as that achieved by consuming a very-low-carbohydrate, high-fat breakfast, substantially reduces postprandial (after-meal) glucose excursions, particularly in the morning, a period when individuals with type 2 diabetes frequently experience the highest blood glucose spikes. In conclusion, improved glycaemic control, such as that achieved by consuming a very-low-carbohydrate, high-fat breakfast, substantially reduces postprandial (after-meal) glucose excursions, particularly in the morning, a period when individuals with type 2 diabetes frequently experience the highest blood glucose spikes.
The Antiacne Activity of Sunkist Peels Methanol Extract in Propionibacterium Acne-Induced Acne Vulgaris Mutia, Maya Sari; Damayanti, Etha Wilda Hasiani; Suyono, Tan; Sihotang, Widya Yanti
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Vol.9 No.2 November 2023
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v9i2.12320

Abstract

Treatment with acne vulgaris is a challenge because the complex pathophysiology of acne vulgaris. One of the natural products that potentially use as a herbal medicine is Sunkist peel. The peel of Sunkist is more inclined to end up as waste from domestic industries. The aim of this study was to investigate the antiacne activity of the Sunkist peel methanol extract gel in vivo study. The experimental study used by applied Sunkist peel extract gel to rats injected intradermally with Propionibacterium acne suspension. One hour before the injection of Propionibacterium acnes suspension, all rats were applied to a topical gel based on the group. Control, standard, Sunkist Peel Extract Gel-I, II, and III groups received gel base, clindamycin, 5%, 10%, and 15% of Sunkist peel extract gel, respectively. This study indicates the methanol extract of Sunkist orange peel with a yield of 8.73% revealed the presence of some phytochemicals, including alkaloids, flavonoids, tannins, and saponins. Sunkist orange peel methanol extract gel significantly reduced the size of acne vulgaris lesions after 7-14 days of extract application (p-value <0.05). It is in line with the histological study that the gel concentration increased, followed by the growth of the epidermal layer. This study sstrongly indicates that Sunkist orange peel methanol extract has an antiacne effect in a physically stable gel form.
The Effect of Sunkist Orange (Citrus Sinensis (L.) Osbeck) Granule Extract on Ovarian Follicle Histomorphology in Female Rats (Rattus Norvegicus) with Obesity Mutia, Maya Sari; Faridahanum, Faridahanum; Silitonga, Impola Dinita Felicia; Ramadhini, Amelya Putri; Sari, Ajeng Mestika; Lubis, Yolanda Eliza Putri; Sihotang, Widya Yanti
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.1 Mei 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Obesity is a medical condition in which a person experiences abnormal fat accumulation that exceeds normal limits, which can have a negative impact on health. Obesity sufferers are increasing, especially in developed and developing countries. The prevalence of obesity is estimated to be 42% in 2030. Risk factors that can cause obesity include unhealthy lifestyles and lack of physical activity. When there is excess fat accumulation in the body, there will be an increase in leptin levels in the body resulting in oxidative stress that triggers the emergence of free radicals that can inhibit the growth of follicles in the ovaries. To neutralize free radicals in the body, antioxidants are needed. One type of fruit that is rich in antioxidants is sunkist oranges (Citrus sinensis (L) Osbeck), this study discusses the effect of giving sunkist orange granule extract (Citrus sinensis (L) Osbeck) on the morphology of ovarian follicles in obese female wistar rats (Ratus norvegicus). Using a laboratory experimental research design with a post-test only control group design, using 25 female rats divided into 5 groups, namely the Negative Control Group, the Positive Control Group (Alloxan and High Fat), and the Treatment Group given alloxan and Sunkist orange granule extract at a dose of 50 mg / kgBW / day, 100 mg / kgBW / day, 150 mg / kgBW / day. Results: Sunkist Orange Granule Extract (Citrus sinensis (L.) Osbeck) has a significant effect on the histomorphology of ovarian follicles with obesity induction in female rats (Rattus norvegicus).
Co-Authors Adeline Sacharissa Firdaus Adrisya Lubis, Putri Anggie Aminuyati Anggraini, Sari Anita Zahra Aulia, Wan Syarifah Buenita, Buenita Chairul, Muhammad Damanik, Anggi Oktavia Damayanti, Etha Wilda Hasiani Dina, Sarah Edison, Rizki Edmi Edy Fachrial Elmiam, Dwi Faridahanum, Faridahanum Fitri Aidani Ulfa Harahap Ginting, Anandestra Ginting, Chrismis Novalinda Ginting, Tarianna Girsang, Ermi Hakim, Mia Amara Hamsi, Ulpah Zahara Harahap, Emira Nadiah Haris, Muhammad Akbar Harmileni Hartono Hartono Henny Henny, Henny Hulu, Victor Trismanjaya Irwanda, Desi Danilah Kurniawan, Muhammad Aditya Leni Diana Leonardi, Felix Lilis Novitarum Lina, Juliana Mahulae, Wigma Aprinda Elizabeth Br Manihuruk, Gresika Br Saragih Maya Sari Mutia Mutia, Maya Sari Nabila, Putri Nasution, Ali Napiah NAUFAL, NAUFAL Ongko, Nicolas Xavier Pane, Putri Yunita Panjaitan, Andrean Kristianto Panjaitan, Hajijah I. L. Paska Ramawati Situmorang Purba, Sarah Putri Uli Endrianda Br Putranto Manalu Putri, Indah Juwita Dwi Rafika, Nazla Ghina Ramadhini, Amelya Putri Rapael Ginting Ratih Nur Indah Siregar Samosir, Frans Judea Santy Deasy Siregar Sari, Ajeng Mestika Septiavianti, Nadia Siagian, Masryna Siahaan, Prestony Petra Habinsaran Sibagariang, Eva Ellya Silalahi, Marlinang I. Silitonga, Impola Dinita Felicia Simangunsong, Pahala Maringan J. Simanullang, Andry Sinaga, Valentino Sinurat, Buenita Sipayung, Yelvreza Rastiani Sitepu, Enda Menaisa Siti Rahma Soleh, Ardian Stephan, Weldy Stephanie Raibalaki Suandy, Suandy SUHARTOMI . Suvina, Vivi Suyono, Tan Syahfitri, Nadia Tampubolon, Jenni Trirasetya, Mutiara Ulfa Wicaksana, Praja Dwi Widyaningsih Widyaningsih, Widyaningsih Yolanda Eliza Putri Lubis Yulizal, Ok Zahran Nst, Mhd Raja Zendrato, Erianto Zendrato, Victorwan Novri Zulfahmi Zulfahmi