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All Journal Buletin Udayana Mengabdi E-Jurnal Medika Udayana WMJ (Warmadewa Medical Journal) Biology, Medicine, & Natural Product Chemistry JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) WICAKSANA: Jurnal Lingkungan dan Pembangunan Journal of Health Sciences Jurnal Sewaka Bhakti Aesculapius Medical Journal Warmadewa Minesterium Medical Journal Indonesian Journal of Cancer Jurnal Sehat Indonesia (JUSINDO) Community Services Journal (CSJ) Physical Therapy Journal of Indonesia Jambura Medical and Health Science Journal Jurnal Pelayanan Hubungan Masyarakat Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Luh Gde Evayanti
Universitas Warmadewa
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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PEMBINAAN KELOMPOK IBU PKK TERKAIT HIPERTENSI KEHAMILAN DAN PEMANFAATAN TANAMAN HERBAL DI DAUHWARU, JEMBRANA Luh Gde Evayanti; Ni Putu Diah Witari; Dewa Ayu Ratna Juwita; Komang Trisna Sumadewi; A.A.Ayu Asri Prima Dewi; Fransiscus Fiano Anthony Kerans; Dewa Ayu Agung Alit Suka Astini
Warmadewa Minesterium Medical Journal Vol. 3 No. 2 (2024): May 2024
Publisher : Warmadewa University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pengetahuan masyarakat terkait adanya hipertensi kehamilan di Kelurahan Dauhwaru masih kurang, terutama komplikasi yang akan dihadapi ibu hamil. Faktor kurangnya pengetahuan ini dipengaruhi oleh sosialisasi yang kurang tentang pentingnya pencegahan maupun kontrol tekanan darah pada ibu-ibu yang hamil. Ada banyak metode untuk menurunkan tekanan darah termasuk pemanfaatan tanaman sayuran sebagai obat herbal, salah satunya adalah pemanfaatan tanaman herbal. Tanaman herbal adalah tanaman yang dapat dipelihara sebagai tanaman lahan sempit di halaman rumah dan dikonsumsi sebagai sayuran atau jus untuk kesehatan. Mitra pengabdian ini adalah kelompok ibu PKK di Kelurahan Dauh Waru. Tujuan pengabdian ini adalah meningkatkan pengetahuan ibu PKK terkait hipertensi kehamilan dan pemanfaatan tanaman herbal kepada ibu-ibu hamil yang ada di lingkungan kelurahan. Metode yang digunakan berupa pembinaan dan praktek langsung cara mengukur tekanan darah mandiri. Selain itu, mitra juga diajarkan cara memelihara tanaman herbal dan memanfaatkannya sebagai tanaman herbal untuk mengontrol tekanan darah tinggi. Mitra juga dievaluasi melakui pre-test dan post-test. Setelah dilaksanakan kegiatan ini, terdapat perbedaan antara post-test dengan nilai pre-test secara signifikan (p < 0,05). Data ini menunjukkan terdapat peningkatan pengetahuan ibu PKK setelah kegiatan.
THE EFFECT OF NOISE EXPOSURE ON THE AVERAGE NUMBER OF TEMPORAL LOBUS NEURONS IN ADULT WISTAR RATS Suka Astini, Dewa Ayu Agung Alit; Evayanti, Luh Gde; Witari, Ni Putu Diah; Sumadewi, Komang Trisna; Prima Dewi, A.A.A Asri; Anthony Kerans, Fransiscus Fiano; Kurniawati, Ida
E-Jurnal Medika Udayana Vol 13 No 07 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i07.P09

Abstract

Noise is defined as unwanted and disruptive sound, considered an environmental stressor and disturbance. Noise encompasses many aspects of modern communities, including work environments. The damaging effects of noise primarily result from the unrestricted production of free radicals into the auditory organs. Exposure to noise causes various health problems, such as hearing impairment, sleep disturbances, and interference with individual performance. Reactive oxygen species (ROS), also known as free oxygen radicals, are normal by-products of cellular aerobic metabolism. These unstable molecules can damage cellular lipids, proteins, and nucleic acids in DNA if the antioxidant balance is disrupted. Acute and chronic exposure to loud noise generates excessive free radicals and disrupts extra-auditory organs such as the nervous, endocrine, and cardiovascular systems. The purpose of this study is to analyze the relationship between noise exposure and the number of neurons in the temporal lobes of Wistar rats. The research design used is a laboratory experimental design, specifically a pure experimental design, implemented with the randomized posttest-only control group design. The research sample consists of 30 male Wistar rats randomized into 2 groups, control and treatment. The treatment group is exposed to 95dB noise for 4 hours per day for 14 days. The rats are then euthanized, and their brain tissue is fixed with 10% neutral buffered formalin. Assessment is performed using Hematoxylin Eosin staining, and analysis is conducted blindly on the average number of neurons in the rat's temporal lobes. Data is subjected to normality testing using the Shapiro-Wilk test and analyzed using independent t-tests for parametric comparison. The results show a significant difference in the mean number of neurons in the temporal lobes between rats exposed to noise and the control group (p <0.005). The conclusion of this study is that noise affects neuron cells in the temporal lobes. Keywords : noise, temporal lobe, neurons.
EVALUATING THE EFFECTIVENESS OF ANATOMY AND HISTOLOGY PRACTICUM DURING COVID-19 PANDEMIC AT FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS WARMADEWA Evayanti, Luh Gde; Sumadewi, Komang Trisna; Witari, Ni Putu Diah; Suka Astini, Dewa Ayu Agung Alit; Kerans, Fransiscus Fiano Anthony; Dewi, A.A.Ayu Asri Prima; Ekayani, Ni Wayan Diana
E-Jurnal Medika Udayana Vol 13 No 6 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i06.P11

Abstract

The implementation of anatomy and histology practical sessions at Fakultas Kedokteran dan Ilmu Kesehatan (FKIK) Universitas Warmadewa during the Covid-19 pandemic still has many variations. This difference in implementation will have an influence on the achievement of student learning. This research aims to evaluate the knowledge of anatomy and histology among students by giving asynchronous learning, pre-test, post-test and practicum exam. This study using cross-sectional approach. 124 participants are 3th semester students whose active status at FKIK Universitas Warmadewa. The primary data were collected directly from practical sessions and practicum exam. The pre-test and post-test data were analyzed using paired-T test (p<0.05). The post-test and practicum exam were analyzed using Spearman rho (p<0.05). In anatomical practicum, there is an increase in post-test scores when compared to pre-test although not significant (p = 0.119). Anatomical practicum exam results have a meaningful positive correlation with post-tests (p = 0.013, r = 0.22). In histological practicum there was a significant increase in post-test scores when compared to pre-tests (p = 0.013), although practicum exam results were not significantly correlated with post-test (p = 0.410). Based on this study, improvements are needed related to technical of anatomical and histological practicums, as well as provisions related to practicums so that activities are structured
The Differences of 10% Neutral Buffered Formalin, 4% Paraformaldehyde, and Bouin Solution in Newborn Rat Brain Luh Gde Evayanti; Ni Putu Diah Witari; Komang Trisna Sumadewi; A.A.Ayu Asri Prima Dewi; Fransiscus Fiano Anthony Kerans; Dewa Ayu Agung Alit Suka Astini
WMJ (Warmadewa Medical Journal) Vol 9 No 1 (2024): May 2024
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.9.1.9180.1-4

Abstract

Rats are widely used in the study of embryological development of the central nervous system and its congenital disorders. Therefore, tissue fixation is very important in obtaining a good picture of the central nervous system, especially in newborn rats. This study aims to determine the difference in fixation using a solution of 10% neutral buffered formalin, 4% paraformaldehyde, and Bouin solution in the brain tissue of newborn rats. This experimental study used a post-test only controlled-group design with 18 newborn rats aged zero day. After randomization, the pups were grouped into 3 treatment groups, namely: fixation with 10% neutral buffered formalin solution (P1, n = 6), and fixation with 4% paraformaldehyde solution (P2, n = 6), and fixation with Bouin solution (P3, n = 6). Assessment using Hematoxylin Eosin staining, and analyzed by blinding based on the histology of the cerebral tissue (cell nucleus staining, cytoplasmic staining, staining clarity, uniformity of staining). Five cerebrum fields were examined. Data analysis used Kruskall Wallis test and post hoc Mann Whitney test using SPSS. The result was a significant difference in the histology of the brain tissue of newborn rats with the fixation of a solution of 10% neutral buffered formalin, 4% paraformaldehyde and Bouin solution (p = 0.001). Brain tissue fixation using 10% neutral buffered formalin solution showed better quality of histological pictures compared to 4% solution of paraformaldehyde solution and Bouin solution (p <0.05).
Hematology Profiles in Colorectal Cancer Patients in Bali Kurniawati, Ida; Dewi, Anak Agung Ayu Asri Prima; Kerans, Fransiscus Fiano Anthony; Witari, Ni Putu Diah; Adyasputri, A A I Ayesa Febrinia; Sueta, Made Agus Dwianthara; Sumadewi, Komang Trisna; Evayanti, Luh Gde; Astini, Dewa Ayu Agung Alit Suka
Jurnal Ilmiah Kesehatan Vol 18 No 01 (2025): Jurnal Ilmiah Kesehatan (Journal of Health Science) 
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/jhs.v18i01.6936

Abstract

Colorectal cancer is a leading cause of cancer-related deaths worldwide. This study explores blood profile and cancer staging in colorectal cancer patients in Bali. It was a descriptive-analytical study that collected demographic and clinical data from medical records of colorectal cancer patients at Prof. Dr. I.G.N.G. Ngoerah Hospital. The results of the study showed the basic characteristics and hematology profiles of 100 colorectal cancer patients. The average age of patients was 55.6 ± 11.4 years, with 54% of the total sample being male. The average body mass index (BMI) was 21.1 ± 3.6 kg/m², with an average height of 161.9 ± 6.1 cm and an average weight of 55.3 ± 10.0 kg. Laboratory tests revealed an average hemoglobin (Hb) level of 11.0 ± 3.6 g/dL, red blood cell count of 4.0 ± 0.9 million/μL, white blood cell count of 11.2 ± 7.3 thousand/μL, and platelet count of 302.8 ± 154.8 thousand/μL. The average hematocrit (HCT) level was 33.7 ± 6.6 L/L. Liver function parameters indicated average aspartate aminotransferase (AST/SGOT) levels of 45.6 ± 63.6 U/L and alanine aminotransferase (ALT/SGPT) levels of 24.6 ± 29.4 U/L. Renal function was described by an average blood urea nitrogen (BUN) level of 21.8 ± 21.0 mg/dL, urea levels of 21.9 ± 21.2 mg/dL, and creatinine levels of 2.3 ± 11.5 mg/dL. Our study highlights the importance of hematology profiles in colorectal cancer patients as part of cancer screening examination. Further study with a larger number of samples and more diverse populations is needed to analyze the relation between variables.
Female gender and time from injury to surgery as risk factors for decreased knee functions in ACL injury survivors Kurniawati, Ida; Witari, Ni Putu Diah; Dewi, Anak Agung Ayu Asri Prima; Kerans, Fransiscus Fiano Anthony; Sumadewi, Komang Trisna; Astini, Dewa Ayu Agung Alit Suka; Evayanti, Luh Gde
Physical Therapy Journal of Indonesia Vol. 6 No. 1 (2025): January-June 2025
Publisher : Universitas Udayana dan Diaspora Taipei Medical University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/ptji.v6i1.247

Abstract

Background: Anterior cruciate ligament (ACL) injuries are serious orthopedic conditions that require long-term recovery and significant costs. This study aimed to assess the risk of decreased knee function among ACL injury survivors in the Indonesian ACL community. Methods: This study used a prospective observational cohort design with a population of all members of the Indonesian ACL community who experienced ACL injury. The primary outcome of this study was a decrease in knee function was measured using the Lysholm knee score. We calculated univariate and multivariate analyses using logistic regression for each variable. Results: The results showed that female gender and time from injury to surgery were significant factors that influenced poor knee function after ACL reconstruction. Women had a significantly higher risk (odd ratio (OR) = 15.28; adjusted OR (AOR) = 23.47; p-value < 0.010). In addition, the time between injury and surgery significantly affected postoperative knee function (AOR = 1.05; p-value = 0.049). Other factors such as age and body mass index did not show significant associations in either univariate or multivariate analyses. Conclusion: This study confirmed that female gender and time from injury to surgery were important factors influencing poor knee function after ACL reconstruction. Timely intervention and focused rehabilitation programs are key steps to improve patient functional outcomes.
Correlation of Age, Tumor Size, and Histopathological Type with Indicator Tumor Progression of Penile Squamous Cell Carcinoma in Bali Astuti, Ni Luh Putu Vina Juni; Lestari, Desak Putu Oki; Sari, Ni Luh Putu Eka Kartika; Armerinayanti, Ni Wayan; Evayanti, Luh Gde; Perdana, I Gede Sukma Okta
Indonesian Journal of Cancer Vol 19, No 3 (2025): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i3.1340

Abstract

Background: Penile cancer is a rare malignancy globally, but Bali accounts for approximately 40% of Indonesia’s cases. Age, tumor size, and histopathological type are recognized factors influencing penile cancer progression, with grade, depth of invasion, lymph node metastasis, and distant metastasis serving as key indicators. However, the prognostic value of these factors, particularly depth of invasion, remains debated. This study aimed to evaluate the correlation between age, tumor size, and histopathological type with indicators of tumor progression in penile squamous cell carcinoma (SCC) in Bali.Method: A cross-sectional analytical study was conducted on 160 cases of penile SCC. Dependent variables included tumor grade, depth of invasion, and lymph node metastasis, while independent variables were age, tumor size, and HPV status (inferred from histopathology). Age was categorized as 60 or ≥60 years, tumor size as 4 cm or ≥4 cm, and depth of invasion as T1–T4. Multivariate analysis using the chi-square test was performed to assess associations.Results:  Most patients were aged ≥ 60 years, had HPV-independent SCC, tumor size ≥ 4 cm, grade 2 tumors, and T1 depth of invasion, with lymph node metastasis observed in a minority. Multivariate analysis revealed significant correlations between age, tumor size, and histopathological type with grade (p = 0.026, R² = 0.056), depth of invasion (p 0.001, R² = 0.445), and lymph node metastasis (p = 0.004, R² = 0.075). Tumor size demonstrated the strongest association with depth of invasion (OR = 9.618, p 0.001) and lymph node metastasis (OR = 6.846, p 0.001).Conclusion: Tumor size is a significant predictor of both depth of invasion and lymph node metastasis in penile SCC. Clinical assessment of tumor size should be emphasized as a key prognostic factor to guide early intervention strategies in patients with penile SCC in Bali.
PELATIHAN KADER REMAJA DALAM MENINGKATKAN KESEHATAN MENTAL Ekayani, Ni Wayan Diana; Indiani, Ni Luh Putu; Ekayanti, Ni Wayan Sri; Wijaya, Putu Austin Widyasari; Evayanti, Luh Gde; Putra, Adi Pratama
JURNAL SEWAKA BHAKTI Vol 11 No 2 (2025): Sewaka Bhakti
Publisher : UNHI Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32795/7922em07

Abstract

Adolescents are vulnerable to stress that can cause behavioral disorders, mental health problems, and self-harm. They undergo many changes physically, psychologically, and socially. The Community Partnership Development Team of the Faculty of Medicine and Health Sciences of Universitas Warmadewa trained adolescent cadres at one of the high schools as part of student empowerment in improving mental health. The training began with material on mental health disorders and self-management, discussion, and a post-test. Thirty participants attended the activity, but only 22 people completed it. The participants comprised 14 women (63.6%) and eight men (36.4%). There were six people (27.3%) who had experienced mental health problems. The mean of the post-test questions was 85.45. This evaluation showed that the participants' understanding of the topic was quite good. The trained youth cadres are expected to help conduct early detection of mental disorders and provide simple counseling to other students. Cooperation between schools and students needs to continue to increase awareness of the importance of adolescent mental health.
Prevalensi Kejadian Anemia pada Siswi SMP Negeri 1 Kintamani Ni Putu Diah Witari; Sri Ratna Dewi; Fransiscus Fiano Anthony Kerans; Aanak Agung Ayu Asri Prima Dewi; Ida Kurniawati; Komang Trisna Sumadewi; Luh Gde Evayanti; Dewa Ayu Agung Alit Suka Astini
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 3 (2025): November : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i3.7411

Abstract

Anemia is a condition characterized by low levels of hemoglobin or red blood cell counts in the bloodstream, resulting in a decreased ability of the blood to transport oxygen throughout the body. The prevalence of anemia is relatively high, especially in developing countries. In Indonesia, there has been an increase in the prevalence of anemia among adolescents aged 15-24 years, reaching 13.6%. In Bali, the recorded prevalence of anemia is 21.9%, with Bangli Regency ranking second. Kintamani is one of the sub-districts located in Bangli Regency, and SMP Negeri 1 Kintamani is one of the middle schools in the area. This study aims to identify the prevalence of anemia among female students of SMP Negeri 1 Kintamani. The method used is a cross-sectional study involving 147 respondents. Hemoglobin levels were measured using the Easy Touch GCHb device. The results indicate that the prevalence of anemia among female students at SMP Negeri 1 Kintamani is 18.37%, with mild anemia at 12.24% and moderate anemia at 6.12%. The majority of respondents are 12 years old.
Phytochemical Screening and Blood Glucose Response of Red Dragon Fruit Extract in Alloxan-Induced Mice Pratiwi, I Gusti Agung Istri Mas Dianti; Maharani, Ni Putu Ayu Dian; Kirana, Ni Made Asthi Pramesti; Utari, Putu Nadya Asti; Arthayasa, I Gede Ngurah Bagus; Evayanti, Luh Gde; Wijaya, Made Dharmesti
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1165-1169

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by elevated blood glucose levels, which can lead to various complications. Natural products, including red dragon fruit (Hylocereus polyrhizus), have gained attention for their potential antidiabetic properties due to their phytochemical content, particularly flavonoids. This study aimed to evaluate the phytochemical composition of red dragon fruit extract and its effect on blood glucose levels in alloxan-induced diabetic mice. Phytochemical screening was conducted qualitatively to identify the presence of secondary metabolites. Male mice were divided into five groups: a negative control group (no treatment), a positive control group (metformin 10 mg/kg BW), and three treatment groups (T1, T2, T3) receiving red dragon fruit extract at doses of 18.2, 36.4, and 72.8 mg/kg BW, respectively. Diabetes was induced by a single intraperitoneal injection of alloxan monohydrate (140 mg/kg BW). Treatments were administered orally once daily for 6 days. Blood glucose levels were measured on days 0, 2, 4, and 6. Data were analyzed using the Friedmann test. Phytochemical screening confirmed the presence of flavonoids, tannins, alkaloids, and saponins in the extract. Statistical analysis showed no significant reduction in blood glucose levels after administration of red dragon fruit extract at any of the tested doses (p>0.05). Red dragon fruit extract did not exhibit a significant antihyperglycemic effect in alloxan-induced diabetic mice under the tested conditions. This may be attributed to suboptimal dosage, insufficient flavonoid concentration, or a less effective mechanism of action compared to standard therapy. Further studies are needed to optimize the formulation and evaluate its potential using different extraction methods or in combination with other bioactive compounds.
Co-Authors A A I Ayesa Febrinia Adyasputri A.A.Ayu Asri Prima Dewi Aanak Agung Ayu Asri Prima Dewi Anak Agung Ayu Asri Prima Dewi Anak Agung Oka Lely Anak Agung Sri Agung Aryastuti Anthony Kerans, Fransiscus Fiano Arthayasa, I Gede Ngurah Bagus Astini, Dewa Ayu Agung Alit Suka Astuti, Ni Luh Putu Vina Juni budiapsari, putu indah Cahyawati, Putu Nita Desak Putu Oki Lestari Dewa Ayu Agung Alit Suka Astini Dewa Ayu Ratna Juwita Dewi, A.A.Ayu Asri Prima Dewi, Anak Agung Ayu Asri Prima Dewi, Ni Made Gita Kusuma Ekayani, Ni Wayan Diana Ekayanti, Ni Wayan Sri Fransiscus Fiano Anthony Kerans Fransiscus Fiano Anthony Kerans I Gede Bagus Gita Pranata Putra I Gede Suranaya Pandit I Gusti Lanang Agung Wiradinata Ida Kurniawati Ida Kurniawati, Ida IGNP Sana Kadek Ayu Alit Sintyawati Kerans, Fransiscus Fiano Anthony Kirana, Ni Made Asthi Pramesti Komang Trisna Sumadewi KT Sumadewi Made Dharmesti Wijaya Maharani, Ni Putu Ayu Dian Manuaba, Ida Ayu Laxmi Ananda Dewi Ni Kadek Elmy Saniathi Ni Luh Putu Indiani Ni Putu Diah Witari Ni Wayan Armerinayanti, Ni Wayan NPD Witari Pande Ayu Naya Kasih Permatananda Perdana, I Gede Sukma Okta Pratiwi, I Gusti Agung Istri Mas Dianti Prima Dewi, A.A.A Asri Putra, Adi Pratama Putu Ayu Kevin Komala Dewi Mahayuna Putri Sari, Ni Luh Putu Eka Kartika Sri Ratna Dewi Sueta, Made Agus Dwianthara Suka Astini, Dewa Ayu Agung Alit Sumadewi, Komang Trisna Utari, Putu Nadya Asti Wijaya, Putu Austin Widyasari Witari, Ni Putu Diah