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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin MEDISAINS Biomedika Indonesian Journal of Medicine Health and Medical Journal Jurnal Ners Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences JOURNAL LA MEDIHEALTICO Cermin Dunia Kedokteran Jurnal Impresi Indonesia Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia Jurnal Bioteknologi & Biosains Indonesia (JBBI) Indonesian Basic and Experimental Health Sciences Jurnal Bioteknologi & Biosains Indonesia
Prasetyadi Mawardi
Universitas Sebelas Maret
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Scabies Risk Factor Analysis in Students at Islamic Boarding School Mawardi, Prasetyadi; Oktavriana , Triasari; Murasmita , Alamanda; Murastami , Ammarilis; Primisawitri , Pratiwi Prasetya; Rosyid , Azhar; Putri , Osdatilla Esa; Pradestine, Sesia
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 3 (2024): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.3.2024.168-173

Abstract

Background: Scabies is a highly contagious skin disease that often occurs in densely populated settings, especially among children, including those in boarding schools. Purpose: We aimed to investigate the risk factors for scabies infestation in boarding schools. Methods: This crosssectional analytic research was conducted at the Imam Syuhodo Modern Islamic Boarding School. This study consisted of four main steps: survey questionnaires, a pre-test, one-on-one doctor examination, and a brief discussion. The collected data was analyzed using the ChiSquare test and bivariate analysis. Additional multivariate analysis was performed to determine the most influential risk factors. Result: The total sample for the study was 490 students (242 males and 248 females). The overall prevalence of scabies in the boarding school was 16.12%. Bivariate analysis showed a significant relationship between male sex, age (<14 years), history of itchiness, and sharing belongings. In the multivariate analysis, sex (OR 5.56, 95% CI 2.5911.93) and age (OR 2.09, 95% CI 1.23-3.56) turned out to be the most significant factor for scabies. Dermatology specific quality of life index assessment showed more severe negative effects on students with scabies (p<0.001). Discussion: Scabies prevalence was more common in younger males patients. The prevalence of male students was very disproportionate, which needs further attention when designing an intervention model. Students in boarding schools dealing with scabies have worse impacts on their daily lives, which could impede their academic progress.
Successful Combination Therapy with Phototherapy and Topical Corticosteroid in a Rare Case : 57 Years Old Male Patient with Lichen Amyloidosis Sambodo, Shelly Lavenia; Mawardi, Prasetyadi; Tansil, Ivana; Dewi, Ayu Kusuma; Utama, Rahmat Firdaus Dwi; Octarica, Stella Gracia; Adjie, Sugih Primas
Indonesian Journal of Medicine Vol. 9 No. 4 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.4.745

Abstract

Background: : Lichen Amyloidosis (LA) is one of the most common forms of primary localized cutaneous amyloidosis, with clinical manifestations of itchy blackish brown hyperkeratotic papules. The most predilection site is the upper extensor of the legs. This case report aims to improve the clinician’s knowledge regarding clinical features and supporting examinations to the provision of appropriate therapy in LA. Case Report: A 57 years old farmer presented to dermatology and venereology outpatient clinic of Dr. Moewardi general hospital with itchy black spots on nearly all over his body since 2 years ago. Dermatology examination obtained generalized papules and scaly hyperpigmented patches. Dermoscopy revealed a scar-like center with a whitish color in the center. Histopathological examination showed an amorphous eosinophilic (amyloid) in the dermis. Congo red examination demonstrated a reddish-orange amyloid. We treated the patient with oral cetirizine 10 mg/day, desoximetasone 0.25% cream applied twice a day in the morning and in the evening, Carmed® cream 20% cream applied twice a day in the afternoon and night, phototherapy 350 MJ/cm2 twice a week. We observed for 14 weeks. The lesion and itching started improving in week 8. Result: Lichen amyloidosis is resulted from amyloid deposits in the papillary dermis which are derived from degradation of basal keratinocytes. The diagnosis is based on history taking, clinical examination, dermoscopy and skin biopsy. The combination of phototherapy and topical corticosteroid can be an option for LA therapy, especially for the symptom of pruritus. Conclusion: Lichen Amyloidosis is the most common type of primary localized cutaneous amyloidosis, presents as blackish brown hyperkeratotic papules. The combined therapy of topical corticosteroids and phototherapy can significantly improve pruritus and skin lesions.
Investigating The Impact of Pruritus on The Quality of Life of the Elderly in Surakarta Nursing Home Oktavriana, Triasari; Mawardi, Prasetyadi; Murastami, Ammarilis; Murasmita, Alamanda; Pradestine, Sesia; Putri, Osdatilla Esa; Lidjaja, Lifesia Natali; Alia, Vrenda; Kusumasari, Nila
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1641

Abstract

Background: The elderly population has been growing rapidly in recent decades. Research has shown that the prevalence of itching (pruritus) increases with age, with 20.8% of individuals aged 60-69 years experiencing it, 22.9% for those aged 70-79 years, and 26% for those aged 75 years and above. Assessing the skin's barrier function by measuring transepidermal water loss (TEWL) using a tool called a Tewameter is important for objectively evaluating dry skin, which is the most common cause of itching in the elderly. It's important to understand how itching affects the quality of life of the elderly, particularly in nursing homes. Objective: This study aims to determine how itching affects the quality of life of the elderly in nursing homes in Surakarta City, especially at PMI Peduli and Aisyiyah Nursing Homes. Methods: This research used an observational, cross-sectional design. Data was collected through interviews using the 5D itch scale questionnaire, and the quality of life was measured using the DLQI (Dermatology Life Quality Index) questionnaire. TEWL levels were also measured using a Tewameter. Results: 29 subjects participated in the interviews, with 69% being women and 31% being men. Most subjects were aged 60-69 years (41%), and the most common comorbidity was hypertension (41%). The 5D Itch Scale questionnaire revealed that itching affected the subjects for less than 6 hours daily (66%), and during the last 2 weeks, itching did not significantly impact the subjects' activities, including sleep, hobbies, housework, and work (51%-69%). The most common location of itching was the back (14%). The DLQI data showed that itching had a severe impact on the subjects (65.5%), followed by a moderate impact (24.1%), and a very severe impact (10.3%). TEWL data indicated that all subjects had an increase of >10 g/h/m2. Conclusion: The study found that itching had a mild impact on the lives and activities of the subjects in general, lasting for less than 6 hours a day. The statistical results showed a positive and significant relationship between the intensity of itching and the quality of life of the elderly with pruritus.
Kelainan Mukokutan dan Infeksi Menular Seksual pada Pasien Anak dengan HIV/AIDS Oktaviani, Trya; Mawardi, Prasetyadi; Putri, Osdatilla Esa; Anandita, Benedikta Lauda
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1628

Abstract

Latar Belakang: Lesi mukokutan dan infeksi menular seksual (IMS) adalah manifestasi umum pada individu yang terinfeksi virus imunodefisiensi manusia (HIV) atau sindrom imunodefisiensi didapat (AIDS). Kelainan mukokutan dan infeksi menular seksual (IMS) pada anak-anak dengan HIV/AIDS dapat muncul dengan gejala atipikal, cenderung lebih parah, dan lebih sulit diobati dibandingkan dengan anak-anak dengan sistem kekebalan yang baik. Tujuan: Penelitian ini dilakukan untuk mengidentifikasi kelainan mukokutan dan infeksi menular seksual (IMS) pada pasien anak dengan HIV/AIDS di Klinik Dermatologi dan Venerologi Rumah Sakit Dr. Moewardi, Surakarta, dari Januari 2020 hingga Desember 2022. Metode: Studi deskriptif retrospektif dilakukan dengan menggunakan data sekunder dari catatan medis pasien anak dengan HIV/AIDS yang mengunjungi poliklinik Dermatologi dan Venerologi di Rumah Sakit Dr. Moewardi, Surakarta, dari 1 Januari 2020 hingga 31 Desember 2022. Hasil: Penelitian ini melibatkan sembilan pasien anak dengan HIV/AIDS, terdiri dari enam laki-laki (67%) dan tiga perempuan (33%). Kelompok usia yang paling banyak diwakili adalah 12-17 tahun, dengan lima pasien (n = 5; 56%). Semua pasien menjalani terapi antiretroviral (ARV) rutin. Manifestasi mukokutan yang paling umum adalah erupsi papular pruritus, diamati pada enam pasien (n = 6; 67%), diikuti oleh dermatitis seboroik dan skrofuloderma, masing-masing mempengaruhi satu pasien (n = 1; 11%). Kondiloma akuminata adalah satu-satunya IMS yang teridentifikasi, hadir pada satu pasien (n = 1; 11%). Tujuh pasien (77%) memiliki jumlah CD4 lebih dari 200 sel/mm³, sedangkan dua pasien (23%) memiliki jumlah CD4 kurang dari 200 sel/mm³. Kesimpulan: Erupsi papular pruritus adalah kondisi mukokutan yang paling umum di antara pasien anak dengan HIV/AIDS, sedangkan kondiloma akuminata adalah IMS yang dominan.
Profile of Skin Diseases in The Ederley at Nursing House Surakarta Mawardi, Prasetyadi; Oktavriana, Triasari; Murastami, Ammarilis; Murasmita, Alamanda; Pradestine, Sesia; Esa Putri, Osdatilla Esa; Lidjaja, Lifesia Natali; Alia, Vrenda; Kusumasari, Nila
Health and Medical Journal Vol 7, No 1 (2025): HEME January 2025
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v7i1.1640

Abstract

Background: The elderly population has been rapidly increasing over the past few decades. In Indonesia, the percentage of elderly residents is 8.75% of the total population. Aging is an unavoidable process, but it requires care to ensure a good quality of life for the elderly. One of the issues affecting the quality of life in the elderly is skin aging. Skin aging causes various complaints, especially itching or pruritus, which can reduce the quality of life for the elderly. Knowledge of the pathophysiology of skin diseases and skin aging, as well as the factors that affect them, particularly skin hydration, is necessary. This research is expected to be beneficial for medical professionals as well as family members of the elderly. The elderly residents at Wreda Griya PMI Peduli and Aisyiyah Nursing Home come from various regions and economic backgrounds. Therefore, the researchers consider the nursing home to be an appropriate place to conduct this study, as it can represent the elderly population from diverse backgrounds across Indonesia.Objective: This study aims to analyze the various skin disease profiles at the Griya PMI Peduli and Aisyiyah nursing homes in the city of Surakarta. Methods: This type of research is a survey using an observational study method with a descriptive design. Results: There were a total of 45 subjects at the Wreda PMI Peduli and Aisyiyah Nursing Home in Surakarta. Among them, 34 subjects had skin complaints, while 11 subjects were excluded because they did not have any skin complaints (7 subjects) or were uncooperative (4 subjects). The most common diagnosis was xerosis cutis (53%). The majority of patients did not have comorbidities (65%), with the most common comorbidity being hypertension (26%). Conclusion: The results of this study indicate that all the main skin complaints among the elderly at Panti Wreda in Kota Surakarta were dominated by itching or pruritus, with xerosis cutis being the primary etiology of pruritus in the elderly subjects of the study, accounting for 53%.
Comparison of the Effectiveness of the Chemosurgery and Cryosurgery for the Treatment of Patients with Condyloma Acuminatum at Dr. Moewardi Hospital, Surakarta Mawardi, Prasetyadi; Febrianto, Bobby; Yuliarto, Danu
Indonesian Journal of Medicine Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.586 KB)

Abstract

Background: Condyloma acuminatum (CA) is one of the most common sexually transmitted infections. Several therapeutic modalities that can be used are chemosurgery with trichloroacetic acid and cryosurgery with liquid nitrogen. Recurrence in CA often occurs, so selecting the right therapeutic modality and eliminating the lesion also prevents recurrence. This study aimed to compare the effectiveness of chemosurgery and cryosurgery therapy in patients with CA who are treated at Dr. Moewardi Hospital, Surakarta.Subjects and Method: A retrospective cross-sectional study was conducted at the Dermatology and Venereology Polyclinic, Dr. Moewardi Hospital, Surakarta, from January 1, 2018, to December 31, 2020. The study subjects were 78 patients diagnosed with CA based on ICD-10 criteria, while chemosurgery and cryosurgery procedures were based on ICD-9. The dependent variable was healing time in weeks. The independent variables were chemosurgery and cryosurgery therapy. The data came from the patient's medical record. Data were analyzed using an independent t-test.Results: Based on univariate analysis, most patients were male (67.9%), and the age group was 20-29 years (51.28%). Most of the CA patients work as private employees (46.15%). The most sexual orientation was heterosexual (53.8%), the most common site of lesions was genital (47.4%), and 52.6% were coinfected with HIV. Most CA patients received chemosurgery (70.5%). Bivariate analysis showed that chemosurgery therapy provided faster clinical improvement (Mean= 23.34; SD= 26.45) than cryosurgery therapy (Mean= 28.69; SD= 19.84), and the difference was statistically significant (p= 0.037).Conclusion: Treatment of CA using chemosurgery provides clinical improvement faster than cryosurgery, so that faster treatment time can reduce treatment costs and improve the patient's quality of life.Keywords: chemosurgery, cryosurgery, HPV, condyloma acuminatumCorrespondence: Prasetyadi Mawardi. Department of Dermatology and Venereology, Faculty of Medicine of Universitas Sebelas Maret/ Dr. Moewardi Hospital, Surakarta, Central Java, Indonesia. Email: prasetyadimawardi@gmail.com/ prasetyadi_m@staff.uns.ac.id. Mobile: +6281229750211.Indonesian Journal of Medicine (2021), 06(03): 290-297https://doi.org/10.26911/theijmed.2021.06.03.06
Hubungan Karakteristik Klinis dengan Gambaran Histopatologi Pasien Karsinoma Sel Basal di RSUD Dr. Moewardi Surakarta Adjie, Sugih Primas; Mawardi, Prasetyadi; Dharmawan, Nugrohoaji; Julianto, Indah
Jurnal Impresi Indonesia Vol. 4 No. 10 (2025): Indonesian Impression Journal (JII)
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i10.7060

Abstract

Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer, with varying clinical and histopathological manifestations. The infiltrative nature of BCC affects tumor aggressiveness and its prognosis. In Indonesia, data regarding the relationship between clinical characteristics and histopathological features of BCC are still limited. This study aims to analyze the relationship between clinical characteristics and the infiltrative nature in BCC patients at Dr. Moewardi General Hospital, Surakarta. A retrospective cross-sectional study used medical records and paraffin blocks of BCC patients diagnosed from January 2021 to February 2025. The evaluated characteristics included age, sex, anatomical location, lesion size, and histopathological subtypes. Histopathological features were analyzed based on infiltrative and non-infiltrative tumor characteristics. Of the 29 patients analyzed, the majority were female (55.2%) with a median age of 57 years. Most lesions were ?2 cm² (82.8%) and located on the middle face (75.9%). The dominant histopathological subtypes were nodulo-ulcerative (41.4%) and nodular (34.4%). Only 48.3% of cases were infiltrative. No significant relationship was found between clinical characteristics and the infiltrative nature of the tumor, emphasizing the importance of histopathological evaluation in determining tumor aggressiveness. These findings are essential for the development of diagnostic and therapeutic strategies for BCC in Indonesia.
Maternal Atopy Diathesis on The Newborn’s Skin Acidity and Hydration Putri, Osdatilla Esa; Widhiati, Suci; Mawardi, Prasetyadi; Kusumawardani, Arie; Mulianto, Nurrachmat; Hidayah, Dwi; Endraputra, Pristiawan
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.50222

Abstract

Background: Atopic diathesis, a hereditary predisposition to allergic disorders such as atopic dermatitis, asthma, and allergic rhinitis, is more strongly transmitted maternally. Maternal atopy may influence neonatal skin barrier development, but evidence on its effect on neonatal skin pH and hydration is limited. Methods: This cross-sectional study was conducted at Dr. Moewardi General Hospital, Surakarta, Indonesia, between March–April 2025. Neonates (28–41 weeks gestation), <24 hours old, and delivered by cesarean section were included. Skin pH was measured on the volar forearm and axilla using a calibrated pH meter, and hydration (water and oil content) was assessed with a Skin Tester. Maternal atopy diathesis was classified by the Erlangen Atopy Score (EAS). Results: Twenty-nine neonates were enrolled, comprising 12 with and 17 without maternal atopy. No significant association was found between maternal atopy and neonatal hydration (water: p = 0.460; oil: p = 0.997) or skin pH (p = 0.876). Conclusion: Maternal atopy diathesis was not associated with neonatal skin pH or hydration in the first 24 hours of life. Early neonatal skin physiology appears to be influenced more by intrinsic maturation than maternal atopic status. Longitudinal studies are needed to assess potential delayed effects.
Profile of Sexually Transmitted Diseases and The Influence of COVID-19 Pandemic on Sexual Transmitted Infection Testing in Dr. Moewardi General Hospital Ellistasari, Endra Yustin; Mawardi, Prasetyadi; Primisawitri, Pratiwi Prasetya; Octarica , Stella Gracia
Indonesian Basic and Experimental Health Sciences Vol. 13 No. 2 (2025): APRIL
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol13iss2pp34-40

Abstract

Introduction Sexually transmitted infections (STIs) are diseases resulting from bacteria, viruses, or parasites transmitted during vaginal, anal, or oral sexual intercourse. The COVID-19 pandemic markedly influenced STI statistics, leading to potential underreporting of cases and heightened transmission rates. Objective : To analyse the profile of sexually transmitted infections and the influence of COVID-19 on STI assessments at the Dermatology and Venereology (DV) Outpatient Clinic of Dr. Moewardi General Hospital. Method A retrospective study using secondary data derived from medical records and registration logs at DV Outpatient Clinic of Dr. Moewardi General Hospital, spanning from January 2018 to December 2022.   Results 284 new STI cases were documented in the before pandemic lockdown period, however during the pandemic lockdown, there was a significant decline of 149 new cases. After the pandemic lockdown, there was 200 additional cases of STIs. Up to 90 patients with STIs were co-infected with HIV. The predominant instance of STIs was condyloma acuminata., and there was a strong correlation between gender and the incidence of STIs (p=0.000; p<0.05) Conclusion There was a sharp decline in STI cases during the COVID-19 pandemic and a surge in STI cases after the COVID-19 pandemic, predominantly featuring instances of condyloma acuminata and syphilis.
THE PATHOPHYSIOLOGY OF CUTANEOUS MANIFESTATIONS RELATED TO COVID-19 Mawardi, Prasetyadi
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 10 No. 2 (2023)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2023.2977

Abstract

Covid-19 is a respiratory infection caused by the newly emerging coronavirus. Covid-19 can also cause skin abnormalities, although the pathophysiology of manifestations of skin disorders associated with Covid-19 has not been understood with certainty. This study aims to discuss the pathophysiology of cutaneous manifestation related to Covid-19. The study was conducted based on literature and data mining related to Covid-19 using PubMed and Google Scholar. Eligible papers provided pathophysiology of cutaneous manifestations related to Covid-19. Papers not available in English were excluded. As a result of the presence of edema, vasodilation, and cellular infiltration, skin lesions such as rash, urticarial, or extensive purpura, or even thrombosis and haemorrhage, arise if damage to the vessels became severe. The pathophysiology of Covid-19-associated skin manifestations is estimated through some different mechanisms, such as lesions found in various Covid-19 patients, namely, the presence of varicella such as eruption, non-characteristic rash, and urticarial. Further studies are required to establish a Covid-19 diagnosis based on skin manifestations.
Co-Authors Abas, Ervianti Adjie, Sugih Primas Alia, Vrenda Aliwardani, Ambar Anandita, Benedikta Lauda Ayu Kusuma Dewi Damayanti, Willa Dewi, Putti Fatiharani Dharmawan, Nugrohoaji Dwi Hidayah Elistasari, Endra Yustin Ellistasari, Endra Yustin Endraputra, Pristiawan Esa Putri, Osdatilla Esa Fatiharani Dewi, Putty Febrianto, Bobby fitriani, fatimah Heryadi, Fanny Fauziyyah Indah Julianto, Indah Irawanto, Muhammad Eko Irfanti, Rakhma Tri Ivani, Ivani Kusumawardani, Arie Lidjaja, Lifesia Natali Mardiana Mardiana Mochtar, Moerbono Muhammad Riza Murasmita , Alamanda Murasmita, Alamanda Murastami , Ammarilis Murastami, Ammarilis Mustifah, Etty Farida Negara, Wisuda Putra Nila Kusumasari Nurfaiqoh, Elok Nurrachmat Mulianto Octarica , Stella Gracia Octarica, Stella Gracia Oktaviani, Trya Oktavriana , Triasari Oktriana, Putri Pradestine, Sesia Prasetyorini, Budi Eko Prihadi, Irfany Arafiasetyanto Primisawitri , Pratiwi Prasetya Primisawitri, Pratiwi Prasetya Putri , Osdatilla Esa Putri, Osdatilla Esa Ratih Pramuningtyas Rini Hastuti Risman, Muhammad Rosyid , Azhar Shelly Lavenia Sambodo Sulistyo Sulistyo Tansil, Ivana Tri Irfanti, Rakhma Triana, Agung Triasari Oktavriana Trisnarizki, Leonardo Ulya, Imroatul Utama, Rahmat Firdaus Dwi Widhiati, Suci Yuliarto, Danu