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All Journal Universa Medicina Jurnal Media Analis Kesehatan Jurnal Kesehatan ISM (Intisari Sains Medis) : Jurnal Kedokteran YARSI Medical Journal INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Poltekita : Jurnal Ilmu Kesehatan Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal Kesmas (Kesehatan Masyarakat) Khatulistiwa Cermin Dunia Kedokteran Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Ebers Papyrus Journal Of Health Science Community Strada Jurnal Ilmiah Kesehatan (SJIK)
Liong Boy Kurniawan, Liong Boy
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Analysis of Urine Podocalyxin in Type 2 Diabetes Mellitus Subjects With and Without Diabetic Nephropathy Pelu, Jusni Ekasari; Kurniawan, Liong Boy; Widaningsih, Yuyun; Zainuddin, Alfian; Umar, Husaini; Nurahmi, Nurahmi; Orno, Theosobia Grace
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 5 No 1 (2023): Step up to strengthen the laboratory system and prepare for patients care
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v5i1.3933

Abstract

Type 2 diabetes mellitus is the most common cause of diabetes, consist from about 85% of cases. Diabetic nephropathy is a complication of diabetes mellitus in the kidneys which can end up as kidney failure. Podocalyxin (PDX) is a protein expressed in kidney podocytes that is involved in various cancers, and is also essential for kidney development. The research design was carried out using observational and cross-sectional analytic methods with total participants of 25 DM with diabetic nephropathy and 25 DM without diabetic nephropathy with a purposive probability sampling technique. This research conducted at the Endocrine Polyclinic, Clinical Pathology Laboratory, Hasanuddin University Medical Research Center (HUM-RC) Laboratory, Hasanuddin University Hospital, Makassar. The results showed that the urinary PDX level in DM subjects with nephropathy were 1.160 ng/mL and DM without nephropathy were 0.167 ng/mL (p<0.001), the urine albumin/creatinine ratio (ACR) of DM subjects with nephropathy were 644.74 mg/ g and DM without nephropathy of 10.071 mg/g (p<0.001) and the correlation test results of urine PDX and urine ACR in DM subjects with nephropathy (r=0.510; p=0.001). This study concluded that there was a significant difference between urinary PDX in DM with and without diabetic nephropathy, there was a significant difference between urine ACR levels in DM with and without diabetic nephropathy, and there was a relationship between urinary PDX levels and urine ACR in DM subjects with diabetic nephropathy.
Co-Authors Adnan, Endy Afandi, Ichlas Nanang Aminuddin Aminuddin Anaam, Andi Khairul Andi Alfian Zainuddin Andi Munawirah Ani Kartini Arif Santoso Ariyandy, Andi Asvin Nurulita Asvin Nurulita Basri, Muhammad Iqbal Chika Pratiwi Darmawati E R Darmawaty ER Darmawaty ER, Darmawaty Darmawaty Rauf Darwati Muhadi Darwati Muhadi Esa, Tenri Fadillah, Ismirayanti Fitriani Mangarengi Fitriani Mangarengi FITRIANI MANGARENGI, FITRIANI Fitry Hamka Gustamin Gustamin Habibah S. Muhiddin Hardyansa, Hardyansa Hasna, Hasna IRFAN IDRIS Kasimat, Maria Magdalena Mansyur Arif Mansyur Arif Mansyur Arif Mansyur Arif Mansyur Arif Martina Rentauli Megawati - Moonika Todingan Muh Taufiq Muh Taufiq Muhammad Fachrul Hidayat Mulyamin, Winda Mustakin Mustakin Mutiah Dwi Humairah Muyadhil Nurindar Nadhifah, Naurah Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi Nurahmi, Nurahmi Nurhayana Sennang Nurhayana Sennang, Nurhayana Nuril Sofiantin Oktarina, Nur Hasni Orno, Theosobia Grace Pelu, Jusni Ekasari Pratiwi, Chika Putri Hidayasyah Purnama Lestari Putri Hidayasyah Purnama Lestari R Satriono Rachmawati Muhiddin Rafiah, Sitti Ratna Dewi Artati Rauf, Darmawaty Ruland DN Pakasi Ruland DN Pakasi Ruland DN Pakasi Ruland DN. Pakasi Samad , Raehana Sheridan, Sabilla Sri Anita Suci Aprianti suci aprianti sukmawaty - Surur, Andi Ainun Zulkiah Suryani Jamal Syafaat, Andi Wali Tenri Esa Uleng Bahrun Uleng Bahrun Uleng Bahrun Uleng Bahrun, Uleng Umar, Husaini Wali Syafaat, Andi Wandani Syahrir Widaningsih, Yuyun Widaningsih, Yuyun Yunita Rapa Yunita Rapa&#039; Yunita Rapa' Yustisia, Ika Yuyun Widaningsih Zainuddin, Alfian