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All Journal MNJ (Malang Neurology Journal) Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Kesehatan Prima Majalah Kedokteran Neurosains Journal of Pain, Vertigo and Headache Journal of Global Pharma Technology Journal of General Procedural Dermatology and Venereology Indonesia IJRETINA - International Journal of Retina Magna Neurologica
Shahdevi Nandar Kurniawan, Shahdevi Nandar
Neurology Department, Medical Faculty, Brawijaya University, Saiful Anwar General Hospital, Malang, Indonesia.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health

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The Correlation Between Cervical Provocation Tests and Compression Severity in EMG Findings of Cervical Root Syndrome Patients Zahra, Farah Shabri Alifia; Kurniawan, Shahdevi Nandar; Petrarizky, Alfred Julius
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.939

Abstract

Background: Medical professionals are often found using cervical provocation tests and Electromyography (EMG) examination to diagnose Cervical Root Syndrome (CRS). Although EMG examinations are unavailable in primary health care facilities due to the lack of equipment, the results of cervical provocation tests are expected to correlate with the findings of the EMG examination. Objective: This study aimed to investigate the correlation between cervical provocation tests (Lhermitte and Spurling) and compression severity of CRS. Methods: 85 medical records that met the inclusion and exclusion criteria were selected using a stratified random sampling method. Subsequently, cervical provocation tests were scaled ordinal, stratified into negative, positive 1, and positive 2, while compression severity was grouped into mild, moderate, and severe. The data obtained was analyzed using SPSS, and correlation analysis was conducted using the Spearman method. Results: The result showed that cervical provocation tests had a very weak negative correlation with the CRS compression severity, and the values obtained were not statistically significant (R = -0.105 and p = 0.341). Conclusion: The results showed that there was no significant correlation between cervical provocation tests and CRS compression severity. Therefore, cervical provocation tests cannot be depended on as a representation of CRS compression severity.
Parkinson’s Disease Quality of Life: Disease Severity Outweighs Pain Impact Raisa, Neila; Maziya, Yulianda; Rahma, Annisa; Harbiyanti, Novita Titis; Kurniawan, Shahdevi Nandar
Jurnal Kesehatan Prima Vol 18, No 2 (2024): AUGUST
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkp.v18i2.1657

Abstract

Introduction: Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer's disease, progressively affecting both motor and non-motor systems in patients. In addition to the commonly recognized motor symptoms such as tremor, rigidity, and bradykinesia, non-motor symptoms such as chronic pain are often underdiagnosed. Pain in Parkinson's patients can manifest in various forms, including musculoskeletal pain, neuropathic pain, and dystonic pain. While pain is not a primary symptom defining Parkinson's, its impact on patients' quality of life is profound, contributing to reduced mobility, sleep disturbances, increased risk of falls, and poor mental health, including depression and anxiety. This study aimed to explore the relationship between the severity of Parkinson's disease, pain levels, and quality of life in Parkinson's patients. Method: A cross-sectional observational study was conducted at the Neurology Clinic of RSUD Dr. Saiful Anwar in East Java from October 2023 to March 2024, using purposive sampling techniques. We assessed Parkinson's severity (Hoehn & Yahr scale), pain levels (Numeric Rating Scale), and quality of life (Parkinson's Disease Questionnaire-39 (PDQ-39) Indonesian Version). Result: The study found that PDQ-39 INA scores were significantly associated with Parkinson's disease severity (n = 11, p = 0.012), indicating a significant impact of disease severity on quality of life. However, no significant relationship was found between PDQ-39 scores and pain levels (p = 0.117). Pearson correlation analysis showed no significant relationship between Parkinson's severity scale and pain level (r = 0.461, p = 0.154). Specifically, Parkinson's severity significantly affected PDQ-39 scores (p = 0.001), while pain levels did not have a significant effect (p = 0.399). Conclusion: This study reveals that while pain is a critical issue, it is the severity of Parkinson's disease that has a more substantial impact on patients' quality of life.
UNRAVELING THE BEST NON-PHARMACOLOGICAL INTERVENTIONS FOR COGNITIVE FUNCTION AND DEPRESSION IN ELDERLY WITH COGNITIVE IMPAIRMENT: A NETWORK META-ANALYSIS Masykur, Umar Jundullah; Janet, Karensa Abby; Putri, Dwi Sandhi Aulia Pramesti; Jatmiko, Sarazata Indi Rozaany; Kurniawan, Shahdevi Nandar
MNJ (Malang Neurology Journal) Vol. 11 No. 1 (2025): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2025.011.01.16

Abstract

Background: Emerging evidence suggests that non-pharmacological interventions can improve cognitive function and alleviate depressive symptoms in elderly individuals with cognitive impairment. However, the comparative effectiveness of these interventions remains unclear. Objective: This network meta-analysis (NMA) compares the efficacy of eight non-pharmacological interventions—Virtual Reality (VR) or Exergame, Computerized Cognitive Training (CCT), Mind-Body Exercise (MBE), Physical Exercise, Music or Art Therapy, Health Education, Treatment as Usual (TAU), and a Control group (no intervention, placebo)—on cognitive function and depression in elderly individuals with cognitive impairment. Methods: Randomized controlled trials (RCTs) published up to August 10, 2024, were systematically searched in Web of Science, PubMed, Embase, and Cochrane Library databases. A Frequentist random-effects network meta-analysis was conducted using R. Results: Total 46 RCTs with 3043 participants were included. The pooled results showed that CCT (SMD = 2.33, 95% CI [1.34, 3.32]), Physical Exercise (SMD = 2.24, 95% CI [1.24, 3.23]), and VR or Exergame (SMD = 2.09, 95% CI [1.10, 3.08]) significantly improved global cognition. VR or Exergame was also effective in enhancing attention (SMD = -3.49, 95% CI [-6.85, -0.14]), executive function (SMD = -75.54 (95% CI [-118.24, -33.04]), and reducing depressive symptoms (SMD = -2.62, 95% CI [-4.08, -1.15]). Conclusion: This NMA highlights the superior efficacy of CCT, Physical Exercise, and VR or Exergame in improving global cognition in elderly individuals with cognitive impairment. Additionally, VR or Exergame is particularly effective for enhancing attention, executive function, and reducing depressive symptoms, suggesting it should be integrated into cognitive rehabilitation programs.
RETINAL NERVE FIBER LAYER THICKNESS ASSOCIATED WITH SEVERITY OF DIABETIC PERIPHERAL NEUROPATHY IN DIABETES MELLITUS TYPE 2 Putri, Mutiara Kristiani; Arfan, Muhammad; Rahmasari, Herisa; Dewi, Nadia Artha; Rosandi, Rulli; Kurniawan, Shahdevi Nandar
International Journal of Retina Vol 8 No 1 (2025): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2025.vol008.iss001.320

Abstract

Purpose: To identify whether the Retinal Nerve Fiber Layer is useful in detecting severity of peripheral neurodegeneration in diabetic patients Methods: A cross-sectional study was conducted. 36 people were enrolled in this study which is divided into two groups. 18 people with type 2 diabetes mellitus (DM) with Diabetic Peripheral Neuropathy (DPN) and 18 people with type 2 DM non-DPN. All subjects were 40-60 years old, and the best corrected visual acuity was better than 0,2 logMAR. An Optical Coherence Tomography (OCT) examination was carried out to determine the Retinal Nerve Fiber Layer (RNFL) thickness, and an Electroneuromyography examination was applied to establish a diagnosis of DPN. Data were analyzed with independent T-test and Spearman correlation analysis. Results: The average RNFL thickness in the DM with DPN was thinner than the RNFL thickness in the DM non-DPN group (100.22 ± 38; vs 102.61±9.11; p 0.444). At temporal quadrant and nasal quadrant, RNFL was also thinner in DM DPN group than DM non-DPN group (71.78±12.21, vs 76.33 ± 8.53, p 0.203; and 75.11±11.38 vs 77.39 ± 14, p 0.596). Sural and tibial amplitude (14.44±2.87 and 6.85± 4.98) , were the most significant predictor values in determining the severity of DPN (p=0.000). Average, temporal, and nasal RNFL thinning has an inverse association with DPN severity (r=-0,285; -0,258;and -0,126) Conclusion: RNFL was thinner at average, temporal, nasal quadrant in the DM group with DPN compared to DM non-DPN group. RNFL thickness has an inverse association with the severity of the DPN although they were not statistically significant. Keywords: Diabetes Mellitus, Diabetic Peripheral Neuropathy, Retinal Nerve Fiber Layer
COMPREHENSIVE REHABILITATION APPROACH FOR MEDIAN NERVE NEUROPATHY COMPLICATED BY CERVICAL RADICULOPATHY: CASE REPORT IN A YOUNG GAME Yudiansyah, Anggi Gilang; Kurniawan, Shahdevi Nandar; Lestari, Dwi Indriani; Pringga, Gutama Arya
Journal of Pain, Headache and Vertigo Vol. 6 No. 1 (2025): March
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2025.006.01.02

Abstract

Background: Median nerve neuropathy, particularly associated with repetitive strain activities such as gaming, is increasingly recognized in clinical practice. This condition often necessitates a multidisciplinary and holistic approach for effective management, aiming to prevent long-term complications and improve functional outcomes. Case: A 21-year-old male presented with progressive weakness, paresthesia, and atrophy in the first three digits of both hands, attributed to excessive gaming, exceeding 12 hours daily. Neurological examination revealed marked weakness in muscles innervated by the median nerve, and electromyography (EMG) confirmed bilateral median nerve compression, compounded by cervical radiculopathy at the C6-7-8-T1 levels. Discussion: This case underscores the necessity of evaluating both peripheral nerve pathology and potential cervical radiculopathy in patients with extensive upper limb use. Intensive gaming, characterized by poor ergonomic practices, can exacerbate nerve compression, leading to significant neuropathic changes. The implemented multidisciplinary rehabilitation approach involved patient education on ergonomic modifications, targeted physical therapy to strengthen affected muscle groups, and strategies to optimize posture and reduce repetitive strain. This comprehensive intervention aimed to alleviate symptoms, restore function, and prevent further deterioration. Conclusion: The case highlights the complexities involved in managing median nerve neuropathy exacerbated by cervical radiculopathy in individuals engaged in repetitive, high-intensity activities. A comprehensive, evidence-based rehabilitation strategy is crucial for achieving optimal recovery, minimizing recurrence, and enhancing the patient’s quality of life. Further research is warranted to explore the long-term efficacy of such interventions and to develop tailored rehabilitation protocols for similar cases in the gaming community.
Parkinson’s Disease Quality of Life: Disease Severity Outweighs Pain Impact Raisa, Neila; Maziya, Yulianda; Rahma, Annisa; Harbiyanti, Novita Titis; Kurniawan, Shahdevi Nandar
Jurnal Kesehatan Prima Vol. 18 No. 2 (2024): AUGUST
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkp.v18i2.1657

Abstract

Introduction: Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer's disease, progressively affecting both motor and non-motor systems in patients. In addition to the commonly recognized motor symptoms such as tremor, rigidity, and bradykinesia, non-motor symptoms such as chronic pain are often underdiagnosed. Pain in Parkinson's patients can manifest in various forms, including musculoskeletal pain, neuropathic pain, and dystonic pain. While pain is not a primary symptom defining Parkinson's, its impact on patients' quality of life is profound, contributing to reduced mobility, sleep disturbances, increased risk of falls, and poor mental health, including depression and anxiety. This study aimed to explore the relationship between the severity of Parkinson's disease, pain levels, and quality of life in Parkinson's patients. Method: A cross-sectional observational study was conducted at the Neurology Clinic of RSUD Dr. Saiful Anwar in East Java from October 2023 to March 2024, using purposive sampling techniques. We assessed Parkinson's severity (Hoehn & Yahr scale), pain levels (Numeric Rating Scale), and quality of life (Parkinson's Disease Questionnaire-39 (PDQ-39) Indonesian Version). Result: The study found that PDQ-39 INA scores were significantly associated with Parkinson's disease severity (n = 11, p = 0.012), indicating a significant impact of disease severity on quality of life. However, no significant relationship was found between PDQ-39 scores and pain levels (p = 0.117). Pearson correlation analysis showed no significant relationship between Parkinson's severity scale and pain level (r = 0.461, p = 0.154). Specifically, Parkinson's severity significantly affected PDQ-39 scores (p = 0.001), while pain levels did not have a significant effect (p = 0.399). Conclusion: This study reveals that while pain is a critical issue, it is the severity of Parkinson's disease that has a more substantial impact on patients' quality of life.
STUDI IMPEDANSI LISTRIK PADA DIABETES MELLITUS` Putri, Laily Ardhianti; Retnaningtyas, Ekowati; Kurniawan, Shahdevi Nandar; Susianti, Hani; Gonius, Andry; Sari, Atika Windra; Widodo, Chomsin Sulistya
Jurnal Penelitian Pendidikan IPA Vol 10 No 7 (2024): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i7.7043

Abstract

Diabetes mellitus has raised concerns about structural and functional changes in blood cells, as well as changes in blood impedance. The purpose of this study is to investigate the relationship between electrical impedance values measured with the Bioelectrical Impedance Analyzer (BIA) in diabetes patients. Blood samples were collected from 5 healthy people and 5 diabetes patients for the study. Electrical impedance testing with a BIA. The impedance method determines the electrical properties of blood by measuring its resistance and reactance at various frequencies. The results of the BIA are analyzed and compared to body health parameters such as the blood glucose level index. The average electrical impedance value in diabetes mellitus patients measured at a frequency of 100 Hz to 100 kHz with a current injection of 10 μA was found to be lower than the average electrical impedance value in healthy people. This study shows that the electrical impedance value of diabetes mellitus patients is lower than the impedance value of healthy people. This is consistent with diabetes mellitus patients' blood glucose levels, which are higher than healthy people's blood glucose levels.
Co-Authors Abdul Gofur Afiyfah Kaysa Waafi Al-Rasyid, Harun Aldita Husna Violita Aldita Husna Violita Andaru Cahya S Anggraini, Vivi Laras Anggraini, Vivid Prety Anisa Syahfitri Hanum Annisatul Hakimah Asmiragani, Syaifullah Auliya Nur Muthmainnina Badrul Munir Badrul Munir, Badrul Basya Adnani Basyar Adnani Chomsin Sulistya Widodo Chozin, Iin Noor Dalhar, Mochamad Damayanti, Ria DAMAYANTI, ZUHRIA PUSPITA Dessika Rahmawati Devi Annisa Devita Anggraeni Soeroso Dewi Permata Sari Dheka Sapti Iskandar Dhelya Widasmara Didi Candradikusuma Dini Jatiya Anggraini, Dini Jatiya Dwi, Pratiwi Suryanti Dyah Kusuma Wardhani Edi Widjajanto Eko Arisetijono Ekowati Retnaningtyas F, Fahimma Fahrani Yossa Prachika Farida Widyastuti Fitria Nikmahtustsani, Mulika Ade Gerry Gunawan, Gerry Gonius, Andry Gyang Hanandita Gusti Putri Hanestya Oky Hermawan, Hanestya Oky Hani Susianti Harbiyanti, Novita Titis Hardi Adiyatma Harun Al Rasyid Helena Era Millennie Heri, Sutanto Herwinda Brahmanti Husnul Khotimah Husnul Khotimah I Ketut Suada Irawan Satriotomo Irsyah Dwi Rohmayanti Izza Ayudia Hakim Janet, Karensa Abby Jatmiko, Sarazata Indi Rozaany Kadek Putri Paramita Abyuda Kartika Agustina Kinesya, Billi Lestari, Dwi Indriani Machlusil Husna Machlusil Husna, Machlusil Made Ayu Hariningsih Sunaga Masruroh Rahayu Masruroh Rahayu Masruroh Rahayu Masruroh Rahayu Masruroh Rahayu Masruroh Rahayu, Masruroh Masykur, Umar Jundullah Maziya, Yulianda Mega Yulia Rusmayanti Michelle Anisa Misnasari, Putri Priela Mochammad Istiadjid Eddy Santoso Mokhamad Fahmi Rizki Syaban Mondiani, Yeni Quinta Muhammad Welly Dafif Nadia Artha Dewi Nadiya Elfira Bilqis, Nadiya Elfira Nasution, Ali Napiah Nata Sanjaya Nectarine Natasya Regitta Yasmin Nidia Suriani Nurvia Andriani Petrarizky, Alfred Julius Pramesti, Fathia Annis Pratiwi, Made Dinda Pringga, Gutama Arya Pudji, Rosalyna Purbasari, Bethasiwi Putri, Dwi Sandhi Aulia Pramesti Putri, Laily Ardhianti Putri, Mutiara Kristiani R, Rahmad Rahma, Annisa Rahmasari, Herisa Rahmawati, Dessika Raisa, Neila Reza Rachmantoko Rislan Faiz Muhammad Rislan Faiz Muhammad Ristiawan Muji Laksono Rizki Rahamatullah Noer Rodhiyan Rakhmatiar Rulli Rosandi Safira Dita Arviana Sari, Atika Windra Sari, Diane Tantia Sari, Diane Tantia Sela Pricilia Siti Nurlaela Sri Budhi Rianawati Sri Budhi Rianawati, Sri Budhi Sri Budi Rianawati Suratmono, Mia Fajarningtyas Syafiatul Azizah Titin Andri Wihastuti Tri Wahju Astuti, Tri Wahju Vely Eva Meria Wa Ode Intan Nur Octina Wahyuni Ramadhani Suaib Widiatmoko, Arif Widodo Mardi Santoso Widodo Mardi Santoso, Widodo Mardi Wirathmawati, Andina Yudiansyah, Anggi Gilang Yuyun Yueniwati Zahra, Farah Shabri Alifia Zamroni Afif