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All Journal Althea Medical Journal Jurnal Berkala Epidemiologi Berkala Ilmu Kesehatan Kulit dan Kelamin Nusantara Medical Science Journal ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Plastik Rekonstruksi JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Jurnal Rekonstruksi dan Estetik

Diah Mira Indramaya

Department Of Dermatology And Venereology Faculty Of Medicine Universitas Airlangga / Dr. Soetomo General Academic Hospital, Surabaya

Author-ID : 563308

Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Other

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Association of Serum Testosterone with Various Severity of Acne Vulgaris in Adult Women Umi Miranti; Diah Mira Indramaya; Hari Sukanto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 2 (2017): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Acne Vulgaris (AV) is a chronic and obstructive inflammatory skin disease of the pilosebaceous unit. Testosterone is main androgen hormone that have a role in the pathogenesis of AV. Pevious researches have shown controversial results regarding serum testosterone levels in AV. Purpose: To evaluate the association of serum testosterone levels with AV severity in adult women in Dermatovenereology Outpatient Clinic of Dr. Soetomo General Hospital Surabaya. Methods: This is an analitic observational study, with 37 patients based on the inclusion and exclusion criteria. Results: Mean serum testosterone level in mild AV group was 39.16 + 24.18µg/dL, moderate AV group was 39.75 + 23.75 µg/dL, and severe AV group was 52.46 + 24.00 µg/dL. These results indicate that serum testosterone level in severe AV group was higher than moderate and mild AV groups. But there was no statistically significant correlation between serum testosterone levels and the severity of AV. Conclusions: Serum testosterone levels in patients with severe AV was higher than moderate and mild AV. No correlation between serum testosterone levels with AV severity in adult women. Further research ruled out confounding factors is needed to determine hormonal role in the pathogenesis of AV.

Artikel asli: Profil Kadar CXCL 10 Serum pada Pasien Vitiligo Di Unit Rawat Jalan Kesehatan Kulit Dan Kelamin RSUD Dr Soetomo Surabaya Ardhiah Iswanda Putri; Sawitri Sawitri; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 31 No. 2 (2019): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Latar Belakang: Vitiligo adalah penyakit depigmentasi yang paling sering dijumpai dengan manifestasi klinis berupa makula berwarna putih susu berbatas tegas, patogenesis kompleks yang belum dipahami dengan baik sehingga evolusi penyakit tidak dapat diprediksi. Peran kemokin CXCL 10 pada vitiligo masih belum banyak diketahui dan dipelajari. Penelitian mengenai kadar CXCL 10 serum pada vitiligo belum pernah dilakukan di Indonesia. Tujuan: Untuk mengetahui profil kadar CXCL 10 serum pada pasien vitiligo. Metode: Rancangan penelitian ini deskriptif cross-sectional yang bertujuan untuk mengevaluasi kadar CXCL 10 serum pada pasien vitiligo, 16 sampel yang didiagnosis vitiligo dilakukan pengambilan darah pada pasien untuk mengukur kadar serum CXCL 10. Hasil: Kadar CXCL 10 serum pada penelitian ini lebih tinggi pada pasien vitiligo, tidak ada perbedaan bermakna antara laki laki dan perempuan dan distribusi proporsi tipe vitiligo tertinggi adalah generalisata. Simpulan: Profil kadar serum CXCL 10 pada pasien vitiligo berdasarkan jenis kelamin, usia, dan lama menderita vitiligo.

A Case Report of Cervicitis Gonorrhea Diah Mira Indramaya; Zahruddin Ahmad; Septiana Widyantari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 2 (2020): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.2.2020.158-162

Background: Gonorrhea refers to a set of clinical conditions involving infection with the sexually acquired bacterial pathogen, Neisseria gonorrhoeae. One of the simplest gonococcal infections in women involves mucosal surfaces of the endocervix that cause cervicitis, a frequently asymptomatic inflammatory condition that results in an abnormal mucopurulent discharge and cervical friability. Purpose: To report a case of cervicitis gonorrhea in a female patient whose sexual partner had a hisstory of unprotected promiscuous intercource with multiple sex worker. Case: A 24-year-old female patient presented with increased vaginal discharge for 4 days. Her husband had a history of having sexual intercourse with a sex worker 8 days before. Physical examination revealed mucopurulent exudate in the genitalia and endocervical canal. The Gram staining showed numerous leucocytes and Gram-negative intracellular diplococci, while the result of polymerase chain reaction (PCR) examination for Chlamydia trachomatis was negative. The patient was treated with single-dose cefixime 400 mg orally and doxycycline 100 mg orally twice a day for 7 days. Discussion: The present case report showed cervicitis gonorrhea co-infected with a nonspecific genital infection that was felt asymptomatic and unintentionally found when the patient accompanied her husband to Sexually Transmitted Infection (STI) clinic. The presumptive treatment of cervicitis directed against N. gonorrhoeae and C. trachomatis in this patient leads to a complete cure of the disease. Conclusion: It is important to treat the sexual partner of a patient with urethritis gonorrhea. The empiric treatment of cervicitis that is directed against N. gonorrhoeae and also against C. trachomatis is mandatory in preventing further possible complications.

A Case of Tinea Incognito: A Misuses of Steroid Diah Mira Indramaya; Abdul Karim; Zahruddin Ahmad
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 31 No. 3 (2019): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Tinea incognito (TI) is a dermatophytic infection which has lost its typical clinical appearance because of improper use of steroids. Topical steroids in Indonesia are often used without prescription. The misuses of steroids has led to the emergence of TI. Clinical diagnosis of TI is still a challenge even by dermatologists, thus lead to a delay treatment. Purpose: To report a case of TI in child. Case: A 10-year-old girl presented with itchy ill defined erythematous patches on the face. The patch had appeared since 2 months before. The patient had already got topical and systemic corticosteroid but there were no improvement. Physical examination showed multiple papules on ill defined scaly erythematous patches on facial region. Potassium hydroxide examination revealed arthroconidia and septate hyphae, while from culture isolation Microsporum gypseum were identified. Diagnosis of TI was successfully made and the patient was treated with griseofulvin two times 125 mg per day orally for four weeks. The patient showed good result. Discussion: TI lesions usually lose their classic annular appearance thus the disease is likely to be confused with other diseases. It is important for dermatologist to consider fungal infection as differential diagnosis of prolong erythematous scaly lesions unresponsive to steroids or calcineurin inhibitors, and encourage of laboratory tests for mycological evaluation. Conclusion: Discontinuance of steroid and adminisration antifungal therapy promoted lesions improvement clinically and mycologically. It is important to regulate the topical steroid distribution and to educate primary care doctors about superficial dermatophytosis to reduce the increasing case of TI.

Efikasi Seramid, Mentol, dan Polidokanol dibandingkan Jeli Petrolatum terhadap Keparahan Dermatitis Atopik Ringan Dewi Nurasrifah; Menul Ayu Umborowati; Diah Mira Indramaya; Iskandar Zulkarnain; Cita Rosita Sigit Prakoeswa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 31 No. 2 (2019): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Latar Belakang: Dermatitis atopik (DA) adalah penyakit kompleks dengan gejala klinis berspektrum luas. Penyakit ini ditandai dengan gejala gatal yang dominan sampai dapat mengganggu kualitas tidur, dan dapat menyebabkan infeksi sekunder. Patogenesis DA meliputi gangguan sawar kulit, faktor lingkungan, agen infeksius, dan abnormalitas sistem imun. Gangguan sawar kulit menjadi faktor utama yang harus diperbaiki salah satunya dengan pemberian pelembap seawal mungkin. Tujuan: Membandingkan efikasi pelembap yang mengandung seramid, mentol, dan polidokanol dengan jeli petrolatum pada pasien DA derajat ringan. Metode: Penelitian ini merupakan penelitian eksperimental analitik dengan menggunakan metode uji klinis acak terkontrol tersamar tunggal, membandingkan terapi pelembap yang mengandung seramid, polidokanol, dan mentol dengan pelembap jeli petrolatum pada pasien DA anak dan dewasa dengan derajat keparahan ringan yang dinilai melalui indeks scoring of atopic dermatitis (SCORAD). Hasil: Penghitungan nilai SCORAD sebelum dan sesudah intervensi pada kelompok perlakuan atau kontrol memiliki perbedaan yang tidak signifikan dengan nilai p>0,05. Simpulan: Pemberian kedua jenis pelembap dapat menurunkan derajat keparahan SCORAD pada pasien DA.

Kualitas Hidup Pasien Dewasa Muda dengan Akne Vulgaris Derajat Sedang di Indonesia Diah Mira Indramaya; Menul Ayu Umborowati; Amanda Gracia Manuputty; Ridha Ramadina Widiatma; Eva Lydiawati; Trisniartami Setyaningrum; Rahmadewi Rahmadewi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 31 No. 3 (2019): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Latar Belakang: Akne vulgaris (AV) adalah penyakit inflamasi kronik yang menyerang unit pilosebasea yang paling banyak menyerang pasien dewasa muda di hampir seluruh negara. Pasien dengan akne vulgaris dapat mengalami tekanan psikologis sehingga memengaruhi kualitas hidup pasien. Tujuan: Mengevaluasi kualitas hidup pasien akne vulgaris derajat sedang. Metode: Merupakan penelitian potong lintang observasional dengan menggunakan kuesioner yang melibatkan pasien AV derajat sedang yang mendapatkan terapi AV standar dan penambahan fototerapi sinar biru pada periode Desember 2017 hingga Februari 2018 di Divisi Kosmetik Medik Unit Rawat Jalan Kesehatan Kulit dan Kelamin RSUD Dr.Soetomo Surabaya. Hasil: Sejumlah 40 pasien berusia 16 – 25 tahun dengan rata-rata 19,22 ± 2,76 tahun. Subjek merasakan AV berefek berat terhadap kualitas hidupnya (65%), diikuti dengan yang merasakan berefek sedang (20%), berefek ringan (10%), berefek sangat berat (2,5%), dan tidak ada efek terhadap kualitas hidup (2,5%). Skor total kuesioner Dermatology Life Quality Index (DLQI) dianalisis korelasi dengan variabel lama sakit dan usia subjek menggunakan uji Spearman’s rho. Analisis tersebut menunjukkan adanya korelasi yang bermakna antara skor DLQI total dengan lamanya subjek menderita AV (p = 0,037; CI 95%). Kekuatan korelasi antar kedua variabel (r) negatif lemah. Hal tersebut berarti semakin lama durasi menderita AV maka semakin kecil skor DLQI total. Skor DLQI total dikatakan tidak berkorelasi dengan usia subjek (p = 0,318; CI 95%). Simpulan: Penelitian ini menunjukkan penurunan kualitas hidup pada pasien akne derajat sedang, dan kualitas hidup berkorelasi dengan lama durasi menderita AV.

Behavior of Sunscreen Usage Among Medical Students Triana Novitasari; Subur Prajitno; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 3 (2020): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.3.2020.174-181

Background: Photoaging is an early skin aging process caused by sun exposure. Sunscreen is effective as a primary photo-protection to protect the skin from the dangers of ultraviolet radiation (UV) sunlight. However, sunscreen is often used in the wrong manner, so that it can reduce the effectiveness of the work of sunscreen. Purpose: To describe the knowledge and the practice of sunscreen usage among medical students of Universitas Airlangga and find out the relationship between the knowledge and the practice of sunscreen usage. Methods: This study is an analytic-observational study. Data were collected through questionnaire sheets that distributed to medical students of Universitas Airlangga class of 2016, 2017, and 2018. The results were analyzed using the Spearman test with a significance level of 1%. Result: Obtained total respondents that fulfilled the inclusion criteria were 159 respondents, with 88.68% were female and 11.32% were male. Based on Fitzpatrick skin type, 55.97% respondents found with skin type-IV. There were 59.12% respondents got score of knowledge in the medium category and 64.78% respondents got score of practice also in the medium category. Based on analytic statistic correlation test between knowledge and practice of sunscreen usage, known that the significance value is equal to 0,006 with coefficient correlation is equal to 0.216. Conclusion: The knowledge and the practice of sunscreen usage among medical students of Universitas Airlangga is already in a fairly good range. There is a parallel relationship between the knowledge and the practice of sunscreen usage among medical students of Universitas Airlangga but with a low level of correlation strength.

Topical Epigallocatechin Gallate (EGCG) 1% for Chronic Plantar Ulcers in Leprosy Riyana Noor Oktaviyanti; Cita Rosita Sigit Prakoeswa; Diah Mira Indramaya; Esti Hendradi; Sawitri Sawitri; Linda Astari; Damayanti Damayanti; Muhammad Yulianto Listiawan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 2 (2020): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.2.2020.134-140

Background: Chronic plantar ulcers in leprosy (CPUL) increase morbidity, increase medical costs, cause loss of productivity, and decrease quality of life. CPUL is a severe complication of leprosy disease with a 10-20% incidence. In general, CPUL consume a significant amount of time to heal. Green tea extract contains high amount of Epigallocatechin gallate (EGCG). EGCG functions as antiinflammatory, antimicrobial, and immunomodulator. This suggests that EGCG is effective for dermal wound treatment by facilitating reepithelialization. Purpose: To investigate the effect of topical EGCG 1% on the CPUL healing process. Methods: The topical EGCG 1% were applied every three days for eight weeks. Size of the ulcers, side effects and possible complications were monitored weekly. Result: There were significant clinical and statistical differences in the size and depth of the ulcers (p=0.000), as observed in the EGCG group. There was no side effect and complication found. Conclusions: Topical EGCG 1% was effective for CPUL healing. Sixty three point six percent of the ulcers were clinically healed, 31.8% demonstrated improvement, and 4.6% no effect was observed.

Skin Aging Profile in Tertiary Hospital: a Descriptive Study Tasya Wikassa; Damayanti Damayanti; Irfiansyah Irwadi; Trisniartami Setyaningrum; Rahmadewi Rahmadewi; Diah Mira Indramaya; Menul Ayu Umborowati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.36-45

Background: Skin aging is a physiological process that involves changes in skin cells and tissues due to abnormal mechanisms and decreased tissue function caused by both intrinsic and extrinsic factors. Skin aging has different clinical manifestations in each individual, which were classified using Glogau's photoaging classification. Purpose: The objective of this descriptive observational study is to evaluate the profile of skin aging patients at Dr. Soetomo General Hospital Surabaya from January – December 2019. Methods: This study utilized a total sampling technique from data obtained from the patients' medical records, which included age, gender, occupation, anamnesis, physical examination, diagnosis, and treatment received by patients. This research has been reviewed by the Ethics Committee at Dr. Soetomo General Hospital Surabaya (0438/KEPK/XII/2021). Result: Based on data obtained from medical records, 415 samples of skin aging patients were collected. The highest number of cases occurred among patients aged 45 - < 60 years. Most patients were female, and the majority of patients’ occupations were private employees. History taking findings include the most common complaint, namely dull skin, with the most precipitating factors discovered in patients, namely exposure to sunlight and pollution. Wrinkles were the most common physical examination finding in patients, with Glogau's photoaging III being the most common diagnosis. Most patients were treated with photoprotection in the form of sunscreen. Conclusion: With the increase of public awareness about appearance, as well as human health and quality of life, skin aging is receiving adequate attention nowadays, with sun exposure being the most common precipitating factor.

Profile of Working-Age Patients with Keloid and Hypertrophic Scar at Dr. Soetomo General Hospital Surabaya in 2014-2017 Fania Ayu Wardani; David Sontani Perdanakusuma; Diah Mira Indramaya
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 12 No. 2 (2021): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V12I22021.84-89

Introduction: Keloid and hypertrophic scar are pathological scars resulting from excessive accumulation of collagen in wound healing process. Data about profiles of keloid and hypertrophic scar are rarely found in Indonesia. Therefore, it is necessary to conduct research related to keloid and hypertrophic scar. This study aimed to provide valuable data for further research.Methods: This was descriptive retrospective study evaluating 105 patients treated for keloid and hypertrophic scar from 2014 to 2017 using medical records of working-age patients.Results: Mostly in patients between 17-25 years old (40%). Comparison between male and female patients were 1.07:1 (keloid) and 1.09:1 (hypertrophic scar). As many as 10.71% of patients of keloid and 17.39% patients of hypertrophic scar were private employees. 23.21% patients with keloid and 23.91% patients of hypertrophic scar were Javanese. 14.29% patients of keloid and 19.57% patients of hypertrophic scar tend to have daily indoor activities. 17.86% patients of keloid and 26.09% patients of hypertrophic scar felt dark-skinned toned. Most keloid scars were caused by traumatic lesions (32.14%), located on the chest (19.54%), and treated by corticosteroid injection. Hypertrophic scar mostly caused by burn injury (54.35%), located on the face (29.55%), and treated by excision surgery.Conclusion: Both keloid and hypertrophic scars were mostly developed in 17-25 years old, male, private employees, Javanese ethnic, dark skin tone patients, with daily indoor activities, caused by traumatic lesion and located on the chest, earlobe, and hand, treated by corticosteroid injection (keloid). Meanwhile, hypertrophic scars are mostly caused by a burn injury on the face and treated by excision surgery.

Co-Authors AA Sudharmawan, AA Abdul Karim Ade Fernandes Afif Hidayati Afif Nurul Hidayati Afif Nurul Hidayati, Afif Nurul Agus Santoso Budi Amanda Gracia Manuputty Anggaraeni, Sylvia Anggun Tera Rahmasari Ardhiah Iswanda Putri Arifa Mustika Arifin Saiboo, Alvian Arisia Fadila Aruja Dhar Astindari Astindari Astindari, Astindari Azzahra, Alya Mutiara Bagus Haryo Kusumaputra, Bagus Haryo Bintanjoyo, Lunardi Brama Rachmantyo Budi Utomo Budi Utomo BUDI UTOMO Budiono Budiono Cita Rosita Sigit Prakoeswa Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti David Sontani Perdanakusuma Devi, Aprilin Krista Dewi Nurasrifah Diana Kartika Sari Dwi Murtiastutik Eliza, Frizka Esravila Ariya Wibisono Esti Hendradi Eva Lydiawati Evy Ervianti Fadila, Arisia Fania Ayu Wardani Farah Meriana Fajrin Hamiseno, Gifta Marshanda Qanitah Hari Sukanto Harningtyas, Citra Dwi Irmadita Citrashanty, Irmadita Irwadi, Irfiansyah Iskandar Zulkarnain Iswinarno Doso Saputro Izzatul Fithriyah Kristina Sihaloho Kristina Sihaloho Kristina Sihaloho, Kristina Lia Kinasih Ayuningati Lia Kinasih Ayuningati, Lia Kinasih Linda Astari, Linda M. Yulianto Listiawan Mah Zhook Yueng Marsudi Hutomo Marsudi Hutomo, Marsudi Maya Wardiana Maylita Sari Maylita Sari, Maylita Medhi Denisa Alinda, Medhi Denisa Meidyta Sinantryana Widyaswari, Meidyta Sinantryana Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati, Menul Ayu Milan Muhammed Muslim, Ronaldo Mutiara Arikah Balqis Novia Indriyani Adisty Novia Indriyani Adisty, Novia Indriyani Nurfaiza, Diandra Yasmin Pepy Dwi Endraswari, Pepy Dwi Perdanakusuma, David Sontani Pramitha, Riezky Januar Priangga Adi Wiratama Prida Ayudianti Pudji Lestari Rahmadewi Rahmadewi Rahmadewi Rebekah Setiabudi, Rebekah Renata Prameswari Ridha Ramadina Widiatma Riyana Noor Oktaviyanti Rochmanti, Maftuchah Rochmanti Rubianti, Marissa Astari Saleh Ashafi Salsabilla, Dhea Hasna Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri Septiana Widyantari Subur Prajitno Sunarso Suyoso Sunarso Suyoso, Sunarso Tasya Wikassa Tengku Riza Zarzani N Triana Novitasari Trisniartami Setyaningrum Umi Miranti Wardiana, Maya Widyantari, Septiana Yuindartanto, Andre Yuli Wahyu Rahmawati Zahrah Hikmah, Zahrah Zahruddin Ahmad Zahruddin Ahmad Zarasade, Lobredia

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