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All Journal Althea Medical Journal Jurnal Berkala Epidemiologi Berkala Ilmu Kesehatan Kulit dan Kelamin Nusantara Medical Science Journal ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Plastik Rekonstruksi JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Jurnal Rekonstruksi dan Estetik
Diah Mira Indramaya
Department Of Dermatology And Venereology Faculty Of Medicine Universitas Airlangga / Dr. Soetomo General Academic Hospital, Surabaya
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Other

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Antifungal Activity of Rosemary (Rosmarinus officinalis L.) Emulsion Gel Compared to Nystatin on Candida albicans Stored Isolate from HIV/AIDS Patients with Oral Candidiasis Wardiana, Maya; Astindari; Ervianti, Evy; Afif Nurul Hidayati; Diah Mira Indramaya; Pepy Dwi Endraswari; Budi Utomo; Dwi Murtiastutik
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 2 (2023): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.2.2023.88-92

Abstract

Background: Oral candidiasis (OC), frequently caused by Candida albicans, is the most common opportunistic infection in HIV/AIDS patients. Topical treatment for OC is limited. In vitro study revealed rosemary (Rosmarinus officinalis L.) essential oil has an antifungal effect. However, the essential oil is volatile and is not recommended to be applied to the skin and mucosa; therefore, emulsion gel (emulgel) is made. Purpose: This study was conducted to evaluate the antifungal activity of rosemary emulgel 6.25%, 25%, 37.5%, and 50% compared to nystatin. Methods: This study is an in vitro test using the disk diffusion method to d  etermine the antifungal activity shown by the inhibitory zones of rosemary emulgel at 6.25%, 25%, 37.5%, and 50% compared to nystatin to stored isolates of C. albicans from HIV/AIDS patients with OC. Result: Rosemary emulgel 6.25% dan 25% did not show antifungal activity because no inhibitory zone was shown. The inhibitory zone diameter provided by rosemary emulgel 37.5%; 50%; and nystatin against C. albicans isolates were 3.17±3.763 mm; 7.00±4.107 mm; and 30.13±5.319 mm respectively. Significant differences in antifungal activity were shown by the inhibitory zone diameter provided between rosemary emulgel 37.5%, 50%, and nystatin (p<0,05). Conclusion: Rosemary emulgel 37.5% dan 50% had antifungal activity showed by the formation of inhibitory zone against Candida species isolates in disk diffusion method even though it was weaker compared to nystatin as a standard antifungal.
Evaluation of Histopathology Findings of Clinically Confirmed Psoriasis Vulgaris Sawitri; Fadila, Arisia; M. Yulianto Listiawan; Priangga Adi Wiratama; Dwi Murtiastutik; Evy Ervianti; Linda Astari; Damayanti; Diah Mira Indramaya; Afif Nurul Hidayati; Medhi Denisa Alinda
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 1 (2023): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.1.2023.21-26

Abstract

Background: Psoriasis vulgaris can be diagnosed clinically. A biopsy is usually used to confirm non-classic cases. The findings of the histopathology feature are not usually present, thus clinical relevance is needed to confirm the diagnosis. Purpose: To describe the histopathology findings from tissue samples of histopathologically confirmed psoriasis vulgaris reported in the Department of Pathology and Anatomy of Dr. Soetomo General Hospital. Methods: A descriptive-retrospective study of pathology-ascertained tissue samples of histopathologically confirmed psoriasis vulgaris was reported in the Department of Pathology and Anatomy from patients who were also previously diagnosed clinically with psoriasis vulgaris in the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital over a period of 2 years. Morphological parameters were observed after histopathology sections were stained with hematoxylin and eosin. Result: Thirty-three tissue samples were examined. Parakeratosis (86%) and hypogranulosis (70.3%) were the most observed findings. Club-shaped rete ridges, suprapapillary plate thinning, and spongiform pustules of Kogoj were the least observed findings (each by 2.7%). Three tissue samples (8.1%) showed only parakeratosis. Only 1 tissue sample (2.7%) showed 4 features (absence of the granular layer, parakeratosis, microabscess of Munro, and spongiform pustules of Kogoj). No tissue sample showed every histopathology finding of psoriasis vulgaris. Conclusion: All of the histopathology features of psoriasis vulgaris are rarely found in one tissue section. Albeit histopathology is believed to be the gold standard diagnosis of psoriasis vulgaris, relevance with clinical findings is still mandatory to support the diagnosis.
Validation and Reliability of Indonesian Version of Vitiligo-Specific Health-Related Quality of Life Instrument (VITIQoL) Indramaya, Diah Mira; Devi, Aprilin Krista; Sawitri; Utomo, Budi; Fithriyah, Izzatul; Murtiastutik, Dwi; Hidayati, Afif Nurul; Cita Rosita Sigit Prakoeswa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 2 (2023): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.2.2023.148-157

Abstract

Background: Vitiligo is a long-term autoimmune disorder marked by the loss of melanocytes and the formation of white macules. Vitiligo can have an impact on the patient's look and quality of life. The Dermatology Life Quality Index (DLQI) is a questionnaire that analyzes the quality of life of skin patients in general, but it is not disease-specific. To assess the quality of life of vitiligo patients in Indonesia, a disease-specific instrument is required. Purpose: This study aims to analyze the validity and reliability of the Vitiligo Quality of Life (VitiQol) questionnaire in Indonesia and translate the VitiQol questionnaire into Indonesian. Methods: Using cross-sectional analytic observation, this study was performed on 39 participants with vitiligo at Dr. Soetomo Surabaya between December 2021 and January 2022. The investigation consisted of three phases: the Indonesian translation of VitiQol, testing for validity, and assessing reliability. Result: The VitiQol questionnaire is a valid and reliable questionnaire. Valid with a correlation coefficient between 0.40 and 0.80 and reliability close to perfection. There was a significant correlation between VitiQol and DLQI (r=0.511, p=0.001). Conclusion: According to the findings of this study, the Indonesian VitiQol is a valid and reliable instrument for measuring the life quality of vitiligo patients in Indonesia.
Profile of Mild Acne Vulgaris Patients at Tertiary Hospital at Surabaya, Indonesia Arifin Saiboo, Alvian; Muhammad Yulianto Listiawan; Sari, Maylita; Indramaya, Diah Mira; Murtiastutik, Dwi; Damayanti; Anggaraeni, Sylvia
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.26-30

Abstract

Background: One of the most prevalent skin conditions worldwide is acne vulgaris (AV). Even mild forms of AV could have an adverse impact on psychological wellbeing. Purpose: To explore the profile of mild AV patients in a tertiary care facility in Surabaya, Indonesia. Method: This was a descriptive study conducted for eight weeks. Data regarding the patient's identity, history, skin type, and complaints related to AV or other complaints that arose were noted on the sample's medical record and collected for analysis. The Lehmann classification was used to assess the AV degree. Result: A total of 34 patients were included. Gender equality was similar in our study, and late adolescence (17-25 years) is the most dominant age group (73.5%). Genetics plays the biggest precipitating factor (73.5%), followed by stress (70.6%). Most patients had an oily skin type (91.2%) with Fitzpatrick's phototype 4 (85.3%). Comedone is the most prevalent lesion in our study (median = 10, range = 4-20). Conclusion: Most patients with mild AV had an oily skin type, and late adolescent is most dominant age group.
Keloid and Hypertrophic Scar Post-Excision Recurrence: A Retrospective Study Azzahra, Alya Mutiara; Perdanakusuma, David Sontani; Indramaya, Diah Mira; Saputro, Iswinarno Doso
Jurnal Plastik Rekonstruksi Vol. 9 No. 2 (2022): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jprjournal.v9i2.343

Abstract

Introduction : Abnormal scar recurrence can occur and often be greater than pre-excision because the recurrence rate is giving a high percentage. Data about keloid and hypertrophic scar recurrence are rarely found in Indonesia. Therefore, it is necessary to conduct research related to abnormal scar, aims to determine the incidence of abnormal scar recurrence to support future research by giving valuable data. Method : A retrospective descriptive study that evaluated post-excision abnormal scar patients from 2018 to 2020 using medical records. Result : The sixteen cases had varied by age with the highest number of presentations in the late adolescence (17-25 years) (31%). Comparison of male (56%) and female (44%) patients were 1.28:1. The distribution of patients with recurrence of abnormal scars based on the type of abnormal scar found that 11 patients (69%) had keloids and the rest had hypertrophic scars with a total of 5 patients (31%) with predominantly ear (38%). Strategies of therapy most commonly excision only (50%), followed by excision with steroid injection combination (31%). Conclusion: This exemplifies recurrence case in post-excision abnormal scar. Our findings indicate that there are differences in surgical strategy, such as wound closure techniques. Most of them were found with keloid scars and the incidence of recurrence was 11 cases and 5 cases experienced more than 1 recurrence. Furthermore, combination therapy, such as steroid injection, which is the most commonly used therapy after excision in this case, did not appear to prevent recurrence.
Correlation between Allergic Rhinitis and History of Infantile Atopic Dermatitis Mutiara Arikah Balqis; Hikmah, Zahrah; Indramaya, Diah Mira; Damayanti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.15-20

Abstract

Background: Atopic march is one of the global health problems that is commonly found in children. The prevalence of allergic rhinitis in Indonesia reaches to 1.5% to 12.4% and continues to increase every year. Allergic reactions can affect all tissues and organs in the body. Some clinical manifestations of allergies are allergic rhinitis, atopic dermatitis, and asthma (atopic march). Atopic march often begins in infancy with the development of atopic dermatitis later in life. Purpose: To analyze the correlation between the prevalence of allergic rhinitis and history of infantile atopic dermatitis in children. Methods: This research used an observational analytic design with a cross-sectional approach. Result: The data were categorized based on a history of atopic dermatitis and the diagnosis of allergic rhinitis. The statistical tests revealed a relationship between the incidence of allergic rhinitis and history of infantile AD in children. The chi-square test yielded a p-value of 0.014 and a contingency coefficient value of 0.213. The odd ratio (OR) value at a confidence level (CL) of 95% and a limit of 1.312 – 6.256 is 2.865, which means that patients who have a history of AD have a 2.8 times higher risk of experiencing AR. Conclusion: The conclusion of this study is that there is a correlation between the incidence of allergic rhinitis and history of infantile atopic dermatitis.
PROFILE OF KELOID PATIENTS IN SURGICAL WOUNDS: A STUDY AT DEPARTMENT OF PLASTIC AND RECONSTRUCTIVE SURGERY, DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA (2019-2022) Nurfaiza, Diandra Yasmin; Saputro, Iswinarno Doso; Indramaya, Diah Mira; Aruja Dhar; Saleh Ashafi; Milan Muhammed
Jurnal Rekonstruksi dan Estetik Vol. 10 No. 1 (2025): Jurnal Rekonstruksi dan Estetik, June 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jre.v10i1.66572

Abstract

Highlights: Previous keloid surgery mostly caused keloid recurrence. The most common symptom that accompanies keloids in surgical wounds was itching. Surgery and combination therapy were the most used therapy. Abstract: Introduction:   Keloid is an abnormal scar resulting from disruptions in the wound healing process. Clinically, keloids extend beyond the original wound margins and progressively enlarge into dense, firm nodules. They can develop following various forms of trauma, including surgical procedures. Several factors contribute to keloid formation in surgical wounds, such as age, gender, genetics, skin color, hormones, incision location, wound tension, and delayed healing. Methods: This retrospective descriptive study analyzes medical records of patients diagnosed with keloids due to surgical wounds at the Department of Plastic and Reconstructive Surgery, Dr. Soetomo General Academic Hospital, Surabaya, between 2019 and 2022. Results: Among 58 keloid patients, 23 developed keloids following surgery. The most common risk factor was a history of previous keloid surgery. The majority of patients were female, aged 17–25 years, students, and had no family history of keloids. The most frequent keloid location was the chest, with an onset of ≥1 year, a size of <20 cm², and associated itching. Surgical excision and combination therapy were the most commonly used treatment approaches. Conclusion: Previous keloid surgery is the primary risk factor for developing keloids in surgical wounds. Surgery and combination therapy remain the most frequently employed treatment strategies.
Co-Authors AA Sudharmawan, AA Abdul Karim Ade Fernandes Afif Hidayati Afif Nurul Hidayati Afif Nurul Hidayati, Afif Nurul Agus Santoso Budi Amanda Gracia Manuputty Anggaraeni, Sylvia Anggun Tera Rahmasari Ardhiah Iswanda Putri Arifa Mustika Arifin Saiboo, Alvian Arisia Fadila Aruja Dhar Astindari Astindari Astindari, Astindari Azzahra, Alya Mutiara Bagus Haryo Kusumaputra, Bagus Haryo Bintanjoyo, Lunardi Brama Rachmantyo Budi Utomo Budi Utomo BUDI UTOMO Budiono Budiono Cita Rosita Sigit Prakoeswa Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti David Sontani Perdanakusuma Devi, Aprilin Krista Dewi Nurasrifah Diana Kartika Sari Dwi Murtiastutik Eliza, Frizka Esravila Ariya Wibisono Esti Hendradi Eva Lydiawati Evy Ervianti Fadila, Arisia Fania Ayu Wardani Farah Meriana Fajrin Hamiseno, Gifta Marshanda Qanitah Hari Sukanto Harningtyas, Citra Dwi Irmadita Citrashanty, Irmadita Irwadi, Irfiansyah Iskandar Zulkarnain Iswinarno Doso Saputro Izzatul Fithriyah Kristina Sihaloho Kristina Sihaloho Kristina Sihaloho, Kristina Lia Kinasih Ayuningati Lia Kinasih Ayuningati, Lia Kinasih Linda Astari, Linda M. Yulianto Listiawan Mah Zhook Yueng Marsudi Hutomo Marsudi Hutomo, Marsudi Maya Wardiana Maylita Sari Maylita Sari, Maylita Medhi Denisa Alinda, Medhi Denisa Meidyta Sinantryana Widyaswari, Meidyta Sinantryana Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati Menul Ayu Umborowati, Menul Ayu Milan Muhammed Muslim, Ronaldo Mutiara Arikah Balqis Novia Indriyani Adisty Novia Indriyani Adisty, Novia Indriyani Nurfaiza, Diandra Yasmin Pepy Dwi Endraswari, Pepy Dwi Perdanakusuma, David Sontani Pramitha, Riezky Januar Priangga Adi Wiratama Prida Ayudianti Pudji Lestari Rahmadewi Rahmadewi Rahmadewi Rebekah Setiabudi, Rebekah Renata Prameswari Ridha Ramadina Widiatma Riyana Noor Oktaviyanti Rochmanti, Maftuchah Rochmanti Rubianti, Marissa Astari Saleh Ashafi Salsabilla, Dhea Hasna Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri Septiana Widyantari Subur Prajitno Sunarso Suyoso Sunarso Suyoso, Sunarso Tasya Wikassa Tengku Riza Zarzani N Triana Novitasari Trisniartami Setyaningrum Umi Miranti Wardiana, Maya Widyantari, Septiana Yuindartanto, Andre Yuli Wahyu Rahmawati Zahrah Hikmah, Zahrah Zahruddin Ahmad Zahruddin Ahmad Zarasade, Lobredia