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All Journal SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Sebatik CARADDE: Jurnal Pengabdian Kepada Masyarakat Jurnal Mandala Pharmacon Indonesia Biopendix: Jurnal Biologi, Pendidikan dan Terapan Reswara: Jurnal Pengabdian Kepada Masyarakat BERNAS: Jurnal Pengabdian Kepada Masyarakat Vivabio : Jurnal Pengabdian Multidisiplin Journal of Health, Education, Economics, Science, and Technology (J-HEST) Bakti Sekawan : Jurnal Pengabdian Masyarakat JURNAL BIOLOGI PAPUA Jurnal Informasi Pengabdian Masyarakat GEMBIRA (Pengabdian Kepada Masyarakat) Sipakaraya : Jurnal Pengabdian Masyarakat Jurnal Sains dan Kesehatan Journal of Biotropical Research and Nature Technology
Felycitae Ekalaya Appa
Universitas Cenderawasih
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : jurnal biologi papua

 1 
Aktivitas Antikoagulan dari Tumbuhan Kayu Ular (Strychnos lucida R.Br.) Elsye Gunawan; Aris A.L. Toruan; Rusnaeni Rusnaeni; Felycitae E. Appa
Jurnal Biologi Papua Vol 14, No 2 (2022)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (347.726 KB) | DOI: 10.31957/jbp.1494

Abstract

The stem of the snakewood plant (Strychnos lucida) has been used empirically as a malaria drug, relieves fever, treats stomach pain, hemorrhoids, rheumatism, stroke symptoms, and improves blood circulation. Tannins as one of the secondary metabolites of snakewood stems contain gallic acid compounds which are known to thin the blood. The purpose of this study was to determine the anticoagulant activity of the ethanolic extract of snakewood stems on blood group samples, namely A, B, AB, and O. The method used for extraction was maceration, for testing anticoagulants used method modified Lee-White and blood smears, as well as for data analysis carried out descriptively. The results obtained by the Lee-White modification method on blood group samples were visually not clotting. For anticoagulant activity by blood smear method, it was shown that microscopically snakewood bark extract prevented the presence of blood clots which could be observed with unrelated blood cells, intact and separated from each other.Key words: S. lucida; Lee-White modification; blood smear; anticoagulants
Quantitative Analysis of Flavonoid Content, Total Phenolic and Toxicity Test of Extract Smilax rotundifolia Leaves From Papua Appa, Felycitae E.; Tobi, Claudius H.B.; Suprapti, Kevry; Bakri, Nur F.; Barus, Andre A.; Pratiwi, Mustika E.
Jurnal Biologi Papua Vol 17 No 1 (2025)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31957/jbp.4539

Abstract

This study investigates Bungkus leaf (Smilax rotundifolia), a well-known plant in Papua commonly referred to as the three-finger leaf. Indigenous Papuans traditionally use this plant to enlarge genitals, buttocks, and breasts, as well as to treat syphilis. The plant is known to contain flavonoid and phenolic compounds with pharmacological activity. This study aimed to determine the total flavonoid and total phenolic content of the 70% ethanol extract of Bungkus leaf. The research began with simplicia preparation, followed by extraction using 70% ethanol. Qualitative tests, including phytochemical screening and thin-layer chromatography (TLC), were conducted, followed by quantitative analysis using UV-Vis spectrophotometry. The results showed total flavonoid content of 54.696 mg QE/g ± 0.565 and total phenolic content of 32.908 mg GAE/g ± 0.263. The study concluded that the total flavonoid content was higher than the total phenolic content. Toxicity testing categorized the extract as toxic, with an LC50 value of 442.92 ppm. 
In vivo study of antipyretic activity of Sampare leaf extract (Glochidion sp.) from Biak-Numfor Regency Bakri, Nur F.; Simanjuntak, Artha M.; Pratiwi, Mustika E.; Jedaut, Agatha C.I.; Pasaribu, Napita P.C.; Appa, Felycitae E.
Jurnal Biologi Papua Vol 18 No 1 (2026)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31957/jbp.5239

Abstract

The local people of Biak Regency use the Sampare Leaf (Glochidion sp.) to cure malaria and reliefe fever. This plant contains flavonoid compounds, alkaloids, saponins, and tannins that can act as antipyretics. This study aims to determine the antipyretic activity and the most effective dosage of Sampare leaf extract as an antipyretic. The research method was a laboratory experimental. The antipyretic testing method used is peptone-induced fever. A total of 30 mice were divided into 6 treatment groups. The inducing solution, peptone, is induced subcutaneously, and the test solution is administered orally. The results showed that Sampare leaf extract had a percent antipyretic power, namely at 150mg/kgBW of 30.17%, a dose of 200mg/kgBW of 49.66%, and a dose of 250mg/kgBW of 70.80%. The ANOVA test showed that the 250mg/kgBW extract treatment group and the 200mg/kgBW dose with the positive control group has no significant difference, so it can be concluded that the 250mg/kgBW extract dose is an effective dose that provides a good antipyretic effect.
Co-Authors A. Muh. Amil Siddik Admawati, Harsi Andre Anusta Barus Arini Anestesia Purba Aris A.L. Toruan Arnold Sau Bakri, Nur F. Basa T Rumahorbo Basa T Rumahorbo Bobi Frans Kuddi Chuvita, Laila Claudius Hendraman B. Tobi Dewi Lidiawati Elfride Irawati, Elfride Eliyah Acantha Manapa Sampetoding Elsye Gunawan Esther Sanda Manapa Febriyanti, Christine Firdaus Fitriya B., Winda Ade Friyuanita Lubis Graciano Aristides Maturbongs Hamzah, Hardi Hardi Hamzah Harsi Admawati Imam Mishbach Irene Sondang Lingga Irmawan, Muhammad Jedaut, Agatha C.I. John Dominggus Kalor John Dominggus Kalor, John Dominggus Juniarto Mende Kalalinggi, Septaria Yolan Krisna Dewi Kuddi, Bobbi Frans Liyatin Gea Lolita Tuhumena Lolita Tuhumena Muayyidah, Nurita A. S. Muhammad Zia Ulhaq Payapo Mustika Endah Pratiwi Nazal, Muhammad Asghar Nicea Roona Paranoan Nunuk Hariani Soekamto Nur Fadilah Bakri Nurhidayah, Annisa Papriani, Nada Pertiwi Pasaribu, Napita P.C. Pattinaja, Yvonne I. Paulangan, Yunus P. Pirhel Pirhel Pitrianti, Siti Pramarselin, Irene Putera, Safii Muhammad Jukwati Rani Dewi Pratiwi Rosa, Stella Rumanasen, David Waranda Rusnaeni Rusnaeni Sara Umbekna Sepsamli, Letus Septaria Yolan Kalalinggi Simanjuntak, Artha M. Sitti Rosnafi’an Sumardi Soltief, Sitti Nurdjaja Suprapti, Kevry Suthelie, Chinry Charolina Tabuni, Frengchy Jalsan Charles Tomasila, Leopold A. Tuhumena, Chrisostommi Wirayudha Umbekna, Sara Winda Ade B Fitriya Winda Ade Fitriya B Yabansabra, Yuliana Ruth Yohana Krisostoma Anduk Mbulang Yuliana Ruth Yabansabra Yulita Sirinti Pongtambing Yunita Pare Rombe Yunus P. Paulangan