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Correlation between Adherence and Effectiveness of Tuberculosis Medication Use among Patients Zuniarto, Ahmad Azrul; TW, Siti Pandanwangi; Annisa, Fatin Maura
Journal La Medihealtico Vol. 5 No. 3 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i3.1281

Abstract

Indonesia has become the country with the second highest number of tuberculosis cases in the world. In 2021, Indonesia recorded an incidence of 397,377 cases, with a significant number of cases originating from Tegal, Central Java, which reported 980 cases. The purpose of this study is to determine the compliance and effectiveness of TB medication usage and to examine the relationship between compliance, effectiveness, and patient sociodemographics. The study population consists of tuberculosis patients at the Tegal Selatan Community Health Center who underwent treatment from September 2023 to February 2024. The research method is quantitative causal. Data collection was conducted both retrospectively and prospectively. Compliance data were obtained through the MMAS-8 questionnaire, and effectiveness data were gathered by recording follow-up sputum examinations using the SITB (Tuberculosis Information System) software. The study included 30 respondents, with 50% male and 50% female. The majority (63.3%) were middle-aged adults (41-60 years old), 63.3% had less than 9 years of education, 60% were employed, 93.3% had an income at or below the minimum city wage, and 70% had 1-3 family dependents. 76.7% of respondents exhibited high compliance, 20% had moderate compliance, and 3.3% had low compliance. The effectiveness of medication usage was 96.7%. Chi-square analysis (95% CI) revealed a strong correlation between compliance and effectiveness with r = 0.707 (p-value = 0.033), and there was no significant relationship between patient sociodemographics and both compliance and effectiveness.
The Relationship Between Nutritional Status And Insulin-Like Growth Factor-1 Levels In Stunted Children In Cirebon Regency Siti Pandanwangi; Akrom; Nurkhasanah; Zuniarto, Ahmad Azrul; Hidayati, Titiek; Tsai, Mei Ling
Window of Health : Jurnal Kesehatan Vol 7 No 3 (July 2024)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.v7i2.1299

Abstract

Insulin-like Growth Factor-1 (IGF-1) is a growth hormone mediator that acts as a growth-promoting factor in the growth process and is also an indicator of the adaptive immune system. Children who experience stunting will experience obstacles to growth and cognitive and motor development, affecting their productivity as adults. This research aims to determine IGF-1 levels and their relationship with stunted children's nutritional status. The research method used was observational, with a cross-sectional research design. The population of stunted children in the Tegalwangi locus area, Cirebon Regency, a sample of children aged 24-60 months who met the inclusion criteria of not being disabled and not being sick, was 50 children. The research began with parents filling in informed consent. Continue to fill in data on date of birth, measure height and weight, take @1ml of the child's blood, and analyze IGF-1 using the ELISA method. The research results were that the average IGF-1 level for men was 16,812 ± 5,164 ng/ml and for women 13,810 ± 5,111 ng/ml. Average IGF-1 levels aged 24-36 months were 14,777 ± 4,742 ng/ml, 36–48 months 17,050 ± 4,280 ng/ml, and 48–60 months 15,214 ± 6,248 ng/ml. Data analysis using the Pearson correlation test obtained a value of p=0.871 based on age, p=0.047 based on gender, p=0.643 based on Height for age, and p=0.245 based on Weight for age (95% CI). The conclusion is that there is a relationship between the age of a stunted child and IGF-1 levels, and there is no relationship with nutritional status. All stunted children have IGF-1 values ​​below the standard value for normal children based on the literature, namely ≥ 28.54 ng/ml.
CORRELATION OF COMMUNITY PHARMACIST KNOWLEDGE, ATTITUDES, AND PRACTICES IN THE DETECTION OF TUBERCULOSIS CASES IN WEST JAVA PROVINCE Mardhiyyah, Cut Ainul; Zuniarto, Ahmad Azrul; Amanatin, Alfitia Dwi; Ryansyah, Hardi; Antonia, Vonny
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 3 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i3.1296

Abstract

Tuberculosis (TB) control is hampered by suboptimal case detection and treatment delays. Pharmacies are reported as a first-aid treatment for patients with TB. Therefore, researchers analyzed knowledge, attitudes, and practices (KAP) regarding TB case detection among community pharmacists, aiming to find innovative strategies to involve community pharmacists in TB case detection. The research aims to determine the level of knowledge, attitudes, and practices, and the relationship between knowledge and attitude, knowledge-practice, and attitude-practice of community pharmacists in detecting tuberculosis cases in West Java Province. This research uses a descriptive observational method with 419 pharmacists who practice pharmacies. The results showed that pharmacists had a sufficient level of knowledge (14.94 ± 1.99), an adequate level of attitude (63.58 ± 9.12), and a sufficient level of practice (20.58 ± 8.55) regarding TB case detection. There is a very low relationship between knowledge and attitude (p-value 0.024<0.05), knowledge and practice ( p-value 0.018>0.05), and attitude and practice ( p-value 0.000< 0.05). This study concluded that community pharmacists in West Java Province have sufficient knowledge, attitudes, and practices in detecting TB cases, but the level of relationship between knowledge attitude and detecting TB cases, and the level of association between knowledge attitude and knowledge practice was very low, while the relationship between attitude practice was low. Keywords: Pharmacist, Knowledge, Practice, Attitude, Tuberculosis
THE COMPLIANCE AND EFFECTIVENESS OF TUBERCULOSIS DRUG USE AT THE TALUN HEALTH CENTER IN CIREBON Regar, Dhea Novakinanda; Zuniarto, Ahmad Azrul; Pandanwangi TW, Siti; Widianingsih, Nining
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1334

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). This disease affects the lung organs and may also affect organs outside the lungs. This study aimed to determine the level of compliance and effectiveness of TB drugs, the relationship between compliance and effectiveness in using TB drugs, and the relationship between compliance and effectiveness based on socio-demographic data of the community. The research method used was descriptive observational, with retrospective data collection based on TB patient treatment cards. Compliance data were collected by completing the MMAS questionnaire, and effectiveness data were collected by recording sputum examination results using the SITB (Tuberculosis Information System) software. The sample comprised the total population according to these criteria. The technique used for sampling was total sampling, namely the total number of TB patients at Talun Health Center, Cirebon Regency, from November 2023 to April 2024, a total of 40 patients. Data analysis using the Spearman test consisted of compliance analysis, effectiveness analysis, the relationship between compliance and effectiveness, and the relationship between compliance and effectiveness based on socio-demographic data of the population. The results of the study showed that the level of compliance with TB drug use was 7.9 (medium level of compliance), and the effectiveness of TB drug use was 100%. There is a relationship between compliance and the effectiveness of TB drug use, but there is no relationship based on the socio-demographic data of the population.  Keywords: Compliance, Effectiveness, TB Drugs
Formulasi Lotion Sari Buah Mangga (Mangifera Indica L.) Sebagai Pelembab Kulit Karphiawati, Aldilla Shalsa; Zuniarto, Ahmad Azrul; Pandanwangi TW, Siti; Karsidin, Bambang; Nafi'ah, Rahma; Zakiah, Fitri; Dewi, Komala
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p28-34

Abstract

Making mango juice lotion (Mangifera indica L.) using various concentration variations is expected to produce mango juice lotion (Mangifera indica L.) which meets the requirements for a good lotion and tests skin moisture against the mango juice lotion formula (Mangifera indica L.). This study aims to determine the best concentration of mango (Mangifera indica L.). In this study, mango juice was obtained by extortion, made in the form of lotion and tested for skin moisture using a Skin Analyzer. Data analysis in the form of SPPS (Statistical Product and Service Solution) tables. The results showed that the addition of the concentration of mango juice (Mangifera indica L.) had an effect on the resulting skin moisture. The selected formula of Mango juice lotion (Mangifera indica L.), namely formula 1 with a concentration of 5%, has a skin moisture value of 70,55%, and Mango fruit juice lotion (Mangifera indica L.).
Pengaruh Home Visit terhadap Kepuasan Konsumen Apotek Palasari Sumedang Zuniarto, Ahmad Azrul; Subagja, Subagja; Nurhasanah, Sarah; Sundari, Retno T; Pandanwangi, Siti
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 15 No 1 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3338.056 KB) | DOI: 10.35617/jfionline.v15i1.80

Abstract

Abstract: In the context of service of pharmaceutical at pharmacy, patients satisfaction is a pleasure feeling appearing in someone’s body after getting service taken directly. The analysis of customer’s satisfaction is based on five dimensions of service quality, which are among others responsiveness, reliability, assurance, empathy, and tangible. The purpose of the research was to find out the influence of home visit activity toward the customer’s satisfaction at Palasari pharmacy Sumedang and the satisfaction level of customer’s satisfaction before and after the home visit activity. This research was a quantitative one where the independent variable was home visit whereas the dependent variable was the customer’s satisfaction at Palasari pharmacy Sumedang. The technic of sample taking was total sampling. The samples used in the research were 34 respondents, they were the PRB patients from Palasari pharmacy at Ganeas district who never take the medicine regularly. The research instruments used in the research was questionnaire of customer’s satisfaction. The results of the study with a questionnaire on the level of consumer satisfaction at Palasari Sumedang Pharmacy before the home visit and after the home visit experienced an increase in percentage results from 75.4% to 81.5% and a simple linear regression test showed that there was an effect of home visits on satisfaction consumer Pharmacy Palasari Sumedang with a value sig. 0.000. Results study show that Home visits are influential to satisfaction consumer Pharmacy Palasari Sumedang with level satisfaction consumers 75.4 % increase to 81.5%.
Comparative analysis of macronutrient, vitamin, and mineral intake between stunted and non-stunted children in cirebon Pandanwangi, Siti; Akrom, Akrom; Nurkhasanah, Nurkhasanah; Zuniarto, Ahmad Azrul
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 2 (2025): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.2.162-169

Abstract

Background: The food consumed by children greatly affects how they will live in the future. The amount of nutrition that enters a child's body affects their health and intelligence. Macronutrients, vitamins and minerals are vital components in the body for the processes of growth and development, endurance, and other important functions. Low nutritional intake in children will cause them to experience growth failure, resulting in stunting.Objectives: This study was to compare the intake of macronutrients (protein, fat, and carbohydrate), vitamins (A, E, B1, B2, B6, C, folate), and minerals (sodium, potassium, magnesium, calcium, phosphorus, iron, and zinc) between stunted and non-stunted childrenMaterials and Methods: This study used a cross-sectional design. The population of the study was toddlers living in the Tegalwangi area, a sample of 100 children, ages 2 to 5, who were willing to sign a consent form as research subjects was split into 50 stunting and 50 non-stunting children. The time for the study began in January-May 2023. Data was collected using the 3x24 hour nutritional recall questionnaire method, followed by converting nutritional intake through the Nutrisurvey softwareResults: Nutritional intake for stunted children, shows that there are 12 intake criteria below the nutritional adequacy rate, while 5 intake criteria meet the standard. While for children who are not stunted, 12 criteria meet and 5 criteria do not meet the nutritional adequacy standard.Conclusion: Analysis of differences in the intake of the two groups found that there were no significant differences in the intake of macronutrients (carbohydrates), vitamins (E, B2) and minerals (sodium, potassium, calcium and phosphorum) with p>0.05, and significant differences in the intake of macronutrients (protein, fat). vitamins (A, B1, B6, C, folate), and minerals (magnesium, iron, zinc) with p<0.05. 
Antioxidant Effects of Temulawak and Black Cumin Honey in Stunted Children: A Study in Cirebon Siti Pandawangi TW; Akrom, Akrom; Nurkhasanah, Nurkhasanah; Ahmad Azrul Zuniarto
Journal of Public Health and Pharmacy Vol. 5 No. 2 (2025): July 2025
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v5i2.5950

Abstract

Introduction: The imbalance between the production of free radicals and the antioxidant defense system in the body will cause the body to experience oxidative stress. This can be caused by chronic malnutrition. In children, this condition causes growth and development failure called stunting. Honey, temulawak and black cumin are herbs with high antioxidant content, formulated in one preparation to test its effectiveness. The purpose of the study was to determine specific descriptions experienced by stunted children and to test the antioxidant effectiveness of preparation temulawak-black cumin honey. Methods: The research method used was quasi-experimental, pre-post design, the research time starts from January-May 2023. The population of Stunting children in the Tegalwangi locus area, Cirebon Regency, the selected samples or subjects are children aged 24-60 months who meet the inclusion criteria. The subjects were divided into 2 groups, namely the treatment group that received the test preparation for 4 months and the control group without the provision of the test preparation. Blood sampling was carried out simultaneously or simultaneously at the village hall with the help of trained analysts. The antioxidant parameters superoxide dismutase, catalase, glutathione peroxidase and free radical parameters Nitric oxide and malondialdehyde. The data obtained will be analysed using an independent t-test. Results: The results of the study on 50 stunted children showed low levels of Superoxide Dismutase, Catalase, Glutathione peroxidase, and free radical parameters Nitric oxide and Malondialdehyde were obtained high. This means that stunted children experience oxidative stress. There was significant antioxidant effectiveness with increased levels of SOD and Catalase in the treatment group (P<0.05), a decrease in NO and MDA in the treatment group (P<0.05) compared to the control group. Conclusion: Temulawak-black cumin honey preparation has activity to reduce oxidative stress in stunted children in Cirebon.
Antibacterial Activity of Katang-Katang Leaf Extract Gel against Staphyloccus Aureus Haryati, Eti; Sugiarto, Anto; Zuniarto, Ahmad Azrul; Hakkin, Atini Sabila
Journal La Medihealtico Vol. 6 No. 3 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i3.1737

Abstract

Infectious diseases are one of the health problems faced by developing countries such as Indonesia. Various methods are used to treat skin infections caused by Staphylococcus aureus bacteria, one of which is traditionally using plants, namely katang-katang leaves which have active compounds of flavonoids, alkaloids, saponins and tannins as antibacterials. This study aims to determine the antibacterial activity of the gel preparation of katang-katang leaf extract (Ipomea pes-caprae) to determine the concentration that has the greatest antibacterial activity and to determine the physical properties. Gel preparations were made with concentrations of 15%, 20%, and 25%. The test method was carried out using the in vitro disc diffusion method and physical properties tests were carried out which included organoleptic tests, homogeneity tests, pH tests, spreadability tests, adhesion tests and viscosity tests. Data analysis was carried out using normality tests, homogeneity tests, anova and post hoc test. The results of research testing the antibacterial activity of katang-katang leaf extract gel at a concentration of 15% was 3.27 mm, 20% was 4.97%, 25% was 5.97 mm, K+ was 10.97 mm and K- was 0 mm. Katang-katang leaf extract gel has antbacterial activity that is not equivalent to the positive control, katang-katang leaf extract gel does not meet the preparation evaluation requirements and is unstable during storage. From these results it can be concluded that the katang-katang leaf extract gel has antibacterial activity against Staphylococcus aureus and the katang-katang leaf extract gel does meet the preparation evaluation requirements and is unstable during storage.
Pengetahuan, Sikap, dan Praktik Apoteker Komunitas dalam Pemantauan Pengobatan Pasien Tuberkulosis di Provinsi dengan Prevalensi Tuberkulosis Tinggi di Indonesia Mardhiyyah, Cut Ainul; Zuniarto, Ahmad Azrul; Ryansyah, Hardi; Amanatin, Alfitia Dwi; Antonia, Vonny; Sumari, Sumari
Jurnal Ilmiah Farmako Bahari Vol 16 No 2 (2025): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v16i2.42294

Abstract

Indonesia ranks second globally in tuberculosis (TB) cases, with West Java identified as a high-burden TB region. Community pharmacists, often the first point of patient contact, have the potential to support TB monitoring. However, their role remains underutilized and understudied. This study aimed to evaluate community pharmacists' knowledge, attitudes, and practices (KAP) in monitoring TB medication, and to examine the relationships among these variables and respondent characteristics. A cross-sectional study was conducted among 419 pharmacists across 27 districts and cities in West Java Province. Data were collected via a validated online questionnaire comprising KAP domains. Descriptive statistics, Spearman’s correlation, and Chi-Square tests were used to analyze relationships between KAP scores and demographic/professional characteristics. Community pharmacists demonstrated moderate knowledge in TB treatment (14.94 ± 1.99), generally have a positive attitude towards the importance of their role and ability to monitor use of TB drug (21.6 ± 3.3). In practice, community pharmacists are low in reporting, monitoring, and providing assistance related to TB patients (10.7 ± 5.2). Significant but low correlations were observed between knowledge and attitude (r = 0.110, p = 0.024), knowledge and practice (r = 0.116, p = 0.018), and attitude and practice (r = 0.343, p < 0.001). Practice scores were significantly associated with access to patient consultation services (p < 0.001), while knowledge was linked to pharmacy location (p = 0.032), and attitude to gender (p = 0.026). Although community pharmacists in West Java show sufficient knowledge and positive attitudes, their involvement in TB monitoring practices remains limited. Targeted education and policy interventions are essential for their engagement in national TB control efforts.
Co-Authors , stf1 ., Rodiya ., Sutisno Afief, Arief R. Ais Hamidah Aisy, Asri Rihadatul Akbar, Rai Fadiilah Amanatin, Alfitia Dwi Andriswana, Dwi Meiria Anjastika, Luky Septiansyah Anna Pradiningsih Annisa, Fatin Maura Antonia, Vonny apriliasanti, Wahyuni Auliya, Muhammad Febri Ayuditiawati, Meita Ita Cantika, Dwi Putri Dewi, Komala Fatmawati, Eva Fauzia, Rizki Rahmah Haerunnisa, Tita Hakkin, Atini Sabila HARYATI, ETI Hasimun, Patonah Husni Mubarok Jajang Japar Sodik Joharudin, Ade Karlina, Elis Karphiawati, Aldilla Shalsa Karsidin, Bambang Khalifah, Tria Incky Mardhiyyah, Cut Ainul Maulida, Nur Afifah Mega Suryani, Mega Meiria A, Dwi Mundzir, Ahmad Mundzir, O Ahmad Mundzir, O. Ahmad Muwahid, Roni Imron Nafi'ah, Rahma Nafilah, Nella Nahdliyah, Vivi Afiyatun Ndang Ikbal Maulana Nopita, Juwita Nopitasari, Sindi noviani, Adis Novianti, Sari Nuari, Ris Ayu Nur Imam Komara Nurfaizi, Deni Nurhasanah, Sarah Nurkhasanah Nurkhasanah Nurkhasanah Putera, Rizky Medino Regar, Dhea Novakinanda Rustanti, Mega Ryansyah, Hardi Sabarudin, Cecep Saefullah, Indah Silviyanti Setriyadi, Dedy Siti Pandanwangi TW Siti Pandawangi TW Subagja . Subagja, Subagja Sugiarto, Anto Sugiharto, Anto Sugiharto, Yuyun Suhada, Tatik Sofiyani Suharmono, Soni Sumari Sumari Sundari, Retno T Supriatna, Cece Susanti, Nina Pratiwi Tamala, Nur Feggy Tanti Tanujaya, Jojon Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tsai, Mei Ling TW, Siti Pandanwangi Wahyuni, Yenny Sri Widianingsih, Nining Yani, Dosi Ahmad Yuniuswoyo, Wirsad Yusniawati, Feni Zakiah, Fitri Zakiyah, Fitri Zanki, Alfriani Melia