Article Per Year (5 Year)
p-Index From 2021 - 2026
3.006
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner VALENSI Saintek Perikanan : Indonesian Journal of Fisheries Science and Technology Proceeding International Conference on Global Resource Conservation Indonesian Journal of Pharmaceutical Science and Technology Jurnal Sumberdaya Hayati BERITA BIOLOGI Jurnal Ilmiah Kedokteran Wijaya Kusuma Omni-Akuatika FITOFARMAKA: Jurnal Ilmiah Farmasi EKOLOGIA : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Jurnal Ilmu Kefarmasian Indonesia Journal of Aquaculture and Fish Health Majalah Farmasetika Journal of Parasite Science The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Kedokteran Hewan Jurnal Veteriner dan Biomedis Current Biomedicine al Kimiya : Jurnal Ilmu Kimia dan Terapan Indonesian Journal of Pharmacology and Therapy
Rahminiwati, Min
INSTITUT PERTANIAN BOGOR
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mathematics Medicine & Pharmacology Public Health Veterinary Other

Published : 51 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 51 Documents
Search

 2   3   4   5   6 
POTENSI INHIBITOR α-GLUKOSIDASE EKSTRAK KASAR Streptomyces tendae SEBAGAI PENURUN KADAR GLUKOSA DARAH PADA TIKUS Sprague Dawley DIABETES: The Potency of Streptomyces tendae Crude Extract as an α-Glucosidase Inhibitor in Lowering Blood Glucose Levels of Diabetic Sprague Dawley Rats Karim, Aliful; Rahminiwati, Min; Lestari, Yulin
Jurnal Sumberdaya Hayati Vol. 12 No. 1 (2026): 2026
Publisher : Departemen Biologi, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jsdh.12.1.8-14

Abstract

Diabetes is a disease caused by insulin dysfunction or impaired insulin production, leading to elevated blood glucose levels (hyperglycemia). It is classified into three types: Type 1, Type 2, and Gestational Diabetes Mellitus (GDM). Type 2 diabetes is a condition resulting from insulin resistance. Previous research has identified microorganisms isolated from Ficus deltoidea that produce α-glucosidase inhibitors. This study aims to determine the potential of extracts derived from Streptomyces tendae as an α-glucosidase inhibitor through both in-vitro and in-vivo assessments, specifically evaluating the extract's effectiveness in reducing blood glucose levels in Sprague Dawley rats with Type 2 diabetes. Although the isolates from previous studies showed a decrease in activity, they remained capable of lowering blood glucose levels in the rats. Statistical analysis of the Oral Glucose Tolerance Test (OGTT) provided sufficient evidence to conclude that the combination of time (minutes) and extract administration significantly influenced the reduction of blood glucose levels in diabetic rats (P<0.05). Diabetes was induced in the rats using low-dose streptozotocin. The results showed that "Dose 1" of the extract significantly reduced blood glucose levels compared to control (aquades) treatment starting from the fifth day of administration and was effective in suppressing further increases in blood sugar (P<0.05).
Co-Authors , Triadiati . andriyanto . Soeripto A.S. Satyaningtijas Achmad Tjahja Ade Sunarma Ade Sunarma Adi Riyadhi Agik Suprayogi Agus Setiyono Ahmad Subhan Ahmad Tjahja Nugraha, Ahmad Tjahja Amrozi Andriyanto . Andriyanto A Andriyanto Andriyanto Anggraena, Shinta Suci Ani Murtisari April Hari Wardhana Arief Boediono Aryani Satyaningtijas Aswani, Tuti Aulia Andi Mustika Bambang Pontjo Priosoeryanto Budi Wirawan Cantika Zaddana Ceristianto Ceristianto Ceristianto, Ceristianto Chudahman Manan Chudahman Manan Daldiyono Daldiyono Daldiyono Daldiyono Damiana Rita Ekastuti Dede Sukandar Deni Noviana Djumali Mangunwidjaja Dyah Iswantini E Mulyati Effendi, E Mulyati Erni Rustiani Fadillah, Wendi Nurul Fajar Triansyah Gumelar Firman, Gelline Tama Anindia Fitri Dwiputri Franco, Christopher MM Gelline Tama Anindia Firman Gumelar, Fajar Triansyah Hajar Hajar Hambarsika, IGM Antara HANDAJANI, FITRI Hidayanti, Tiyan Huda Shalahudin Darusman IETJE WIENTARSIH Ika Amalia, Ika Ike Yulia Wiendarlina Indriani, Lusi Irmanida Batubara Ita Djuwita Ita Juwita Joshie Ramadhan Juwita, Ita Karim, Aliful Kusdiantoro Mohamad La Ode Sumarlin La Ode Sumarlin latifah K Darusman latifah K Darusman Latifah Kosim Darusman Lina Novianti Sutardi Livana Dethris Rawung M. Agung Zaim Adzkiya M. Zairin Junior Mahyuni, Siti Martha Arofa Dilla Mashuri Waite Meyliana Wulandari MUHAMMAD AGUS SUPRAYUDI Murtisari, Ani Mutiara, Tia Najwa Rokhmah, Nisa Nampiah Sukarno Neni Nuryani Nhestricia, Nhadira Novriyandi Hanif Oom Komala Rahmania Hanim Rahmat Hidayat Raudhatul Jannah Rosihan Rosman SAEPUDIN RAHMATULLAH Sara Nurmala Shinta Suci Anggraena Sholehah, Akipah Nazla Siti Saadah Siti Sa’diah Sri Budiarti Poerwanto Sri Estuningsih Sri Nuryati Suci Sintya Sulistyaningsih, Yohana Caecilia SUMINAR S. ACHMADI Supardi, Arviani Rahmawati Tia Mutiara Tuti Aswani Ulandari, Rafika Unang P. Unang Patriana Upik Kesumawati Hadi Waite, Mashuri Wasmen Manalu Wei Zhang Wendi Nurul Fadillah Wida Lesmanawati Widia Safitri Yasinta Ratna Esti Wulandari Yohana Caecilia Sulistyaningsih YULIN LESTARI Zaenal Abidin