Article Per Year (5 Year)
p-Index From 2020 - 2025
3.218
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner VALENSI Jurnal Veteriner Saintek Perikanan : Indonesian Journal of Fisheries Science and Technology Proceeding International Conference on Global Resource Conservation Indonesian Journal of Pharmaceutical Science and Technology BERITA BIOLOGI Jurnal Ilmiah Kedokteran Wijaya Kusuma Omni-Akuatika FITOFARMAKA: Jurnal Ilmiah Farmasi EKOLOGIA : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Jurnal Ilmu Kefarmasian Indonesia Journal of Aquaculture and Fish Health Majalah Farmasetika Journal of Parasite Science The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Kedokteran Hewan Jurnal Veteriner dan Biomedis Current Biomedicine al Kimiya : Jurnal Ilmu Kimia dan Terapan Indonesian Journal of Pharmacology and Therapy
Rahminiwati, Min
INSTITUT PERTANIAN BOGOR
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mathematics Medicine & Pharmacology Public Health Veterinary Other

Published : 55 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 55 Documents
Search

 2   3   4   5   6 
DAYA HAMBAT EKSTRAK HEKSAN, ETIL ASETAT DAN ETANOL DARI DAUN ASAM KANDIS (Garcinia parvifolia (Miq.) Miq.) TERHADAP AKTIVITAS ENZIM ?-GLUKOSIDASE SECARA IN VITRO Min Rahminiwati; Ike Yulia Wiendarlina; Ceristianto Ceristianto
FITOFARMAKA: Jurnal Ilmiah Farmasi Vol 6, No 2 (2016): Fitofarmaka Jurnal Ilmiah Farmasi
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.069 KB) | DOI: 10.33751/jf.v6i2.755

Abstract

ABSTRAKSalah satu penyebab peningkatan kadar gula darah pada penderita penyakit diabetes mellitus adalah tingginya aktivitas pemecahan karbohidrat menjadi glukosa oleh enzim ?-glukosidase. Beberapa penelitian menunjukan bahwa daun asam kandis diketahui memiliki kandungan senyawa xanthone yang mampu menghambat aktivitas enzim ?-glukosidase. Penelitian ini bertujuan untuk mengetahui aktivitas antidiabetes ekstrak heksan, etil asetat dan etanol daun asam kandis (Garcinia parvifolia (Miq.) Miq.) dengan mengukur daya hambat ekstrak daun asam kandis terhadap aktivitas enzim ?-glukosidase secara in vitro. Pengujian daya hambat terhadap aktivitas ?-glukosidase dihitung berdasarkan nilai IC50 dengan senyawa acarbose sebagai pembanding (kontrol positif). Hasil uji daya hambat ekstrak daun asam kandis terhadap aktivitas enzim ?-glukosidase menunjukan bahwa aktivitas inhibisi (IC50) dicapai pada pemberian ekstrak heksan, etil asetat dan etanol daun asam kandis berturut-turut sebesar 226,4 24,18 ppm, 46,96 10,48 ppm, dan 7,32 2,14 ppm. Dari hasil penelitian dapat disimpulkan bahwa ekstrak etanol berpotensi paling tinggi sebagai inhibitor enzim ?-Glukosidase.Kata Kunci: Antidiabetes, asam kandis, inhibitor ?-glukosidase
AKTIVITAS HEPATOPROTEKTOR KOMBINASI EKSTRAK AIR PEGAGAN (Centella asiatica L. Urban) DAN EKSTRAK ETANOL KUNYIT (Curcuma longa Linn) TERHADAP TIKUS PUTIH JANTAN SPRAGUE DAWLEY Gelline Tama Anindia Firman; Min Rahminiwati; Ike Yulia Wiendarlina
FITOFARMAKA: Jurnal Ilmiah Farmasi Vol 7, No 1 (2017): Fitofarmaka Jurnal Ilmiah Farmasi
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (736.457 KB) | DOI: 10.33751/jf.v7i1.797

Abstract

ABSTRAKHepatoproktektor adalah senyawa yang dapat mencegah dan memperbaiki sel-sel hepar yang rusak. Parameter yang diamati adalah perubahan kadar SGPT pada hari ke 0,2, 5, 9 dan 13. Hasil penelitian dari 9 kombinasi dosis selama 13 hari menunjukkan semua kombinasi menurunkan kadar SGPT dengan aktivitas hepatoprotektor terbaik adalah terdapat pada tumbuhan ektrak air pegagan: ekstrak etanol kunyit dengan perbandingan 2:3.Kata kunci: Pegagan (Centella asiatica L.Urban), Kunyit (Curcuma longa Linn) dan hepatoprotektorABSTRACTHepatoprotector is a compound that can prevent and repair liver cell damage. This research aimed to study the activity and effectivity of combination Centella asiatica water extract and Curcuma longa ethanol extract as hepatoprotector by SGPT (Serum Glutamat Piruvat Transaminase) in Sprague Dawley male white rats induced paracetamol. Parameters measured were changes in ALT levels at day 0, 2, 5, 9 and 13. Combinations of doses for 13 days showed all combinations of those extract potencial hepatoprotector. The best activity was found in ratio 2:3 (Centella asiatica extract:ethanol extract of turmeric).Keywords: Centella asiatica L. Urban, Curcuma longa Linn and Hepatoprotector
STUDI PERBANDINGAN EFEK DIURETIK DAN ANTIINFLAMASI GABUNGAN EKSTRAK SIDAGURI, TEMPUYUNG DAN SELEDRI PADA TIKUS Min Rahminiwati; Raudhatul Jannah; Kusdiantoro Mohamad
FITOFARMAKA: Jurnal Ilmiah Farmasi Vol 11, No 2 (2021): FITOFARMAKA | Jurnal Ilmiah Farmasi
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jf.v11i2.2999

Abstract

Sidaguri (Sida rhombifiola L.), tempuyung (Sonchus arvensis L.), dan seledri (Apium graveolens L.) dilaporkan mengandung flavonoid yang berperan penting dalam mekanisme terjadinya efek diuretik dan antinflamasi beragam herbal. Namun potensi flavonoid dalam menimbulkan kedua efek tersebut berbeda pada setiap tanaman baik tunggal maupun ramuan. Penelitian ini ditujukan untuk mempelajari kekuatan efek diuretik dan antiinflamasi dari gabungan ketiga tanaman tersebut pada tikus. Lima ekor tikus dari masing masing kelompok uji diuretik dan 4 ekor tikus dari kelompok antiinflamasi diberi aquadest sebagai grup kontrol, ekstrak tempuyung 28 mg/200 g BB, dan kombinasi ketiga tanaman dosis 28 mg/200 g BB, 56 mg/200 g BB, dan 280 mg/200 g BB secara oral selama 8 hari berturut turut. Total volume urin kelompok tikus diuretik diukur pada hari ke 8 sampai dengan hari ke 10 sedangkan volume udem kaki tikus yang diinduksi karagenan kelompok tikus antiinflamasi diukur 30 menit sebelum dan sesudah induksi dan setiap jam selama 6 jam. Data yang diperoleh menunjukkan bahwa sediaan dosis 56 mg/kg BB mempunyai total volume urin dan percent diuretic index lebih besar dari kontrol dan pada dosis 28 mg/kg BB mempunyai nilai AUC terendah serta % DAI tertinggi. Dengan demikian sediaan. mempunyai efek antiinflamasi lebih kuat dibandingkan dengan efek diuretik.
AKTIFITAS HEPATOPROTEKTOR EKSTRAK AIR HERBA PEGAGAN DAUN KECIL (Centella asiatica L. Urb.) TERHADAP TIKUS PUTIH JANTAN Sprague Dawley L. YANG DIINDUKSI DENGAN PARASETAMOL Ike Yulia Wiendarlina; Min Rahminiwati; Fajar Triansyah Gumelar
FITOFARMAKA: Jurnal Ilmiah Farmasi Vol 8, No 1 (2018): FITOFARMAKA | Jurnal Ilmiah Farmasi
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (841.767 KB) | DOI: 10.33751/jf.v8i1.1167

Abstract

Hepatoprotektor merupakan senyawa yang dapat mencegah dan memperbaiki sel hati yang rusak akibat metabolism senyawa toksik. Penelitian ini bertujuan untuk mengetahui aktivitas hepatoprotektor dan dosis efektif dari ekstrak air herba pegagan daun kecil (Centella asiatica L. Urb) terhadap tikus putih jantan Sprague Dawley yang diinduksi dengan parasetamol. Tikus putih jantan galur Sprague Dawley L. yang digunakan berumur 3-4 bulan dengan bobot 180 g – 220 g. Tikus diinduksi parasetamol dengan dosis 180 mg/200 g BB untuk menaikan kadar SGPT (Serum Glutamat Piruvat Transaminase). Selanjutnya tikus diberi perlakuan ekstrak herba pegagan dan diukur penurunan kadar SGPT selama 14 hari.  Hasil penelitian menunjukkan adanya aktivitas hepatoprotektor pada ekstrak air herba pegagan dengan persentase penurunan kadar SGPT pada dosis 50 mg/200 g BB, dosis 25 mg/200 g BB, dosis 12,5 mg/200 g BB dan dosis 6,25 mg/200 g BB masing-masing sebesar 77,81%, 38,46%, 79,95% dan 55,20%. Berdasarkan penurunan kadar SGPT dan hasil histopatologi jaringan hati, ekstrak pegagan dosis 12,25 mg/200 g BB merupakan dosis paling efektif untuk menurunkan kadar SGPT pada tikus uji. 
PERBANDINGAN POTENSI ANALGETIK EKSTRAK ETANOL DAN AIR UMBI RUMPUT TEKI (Cyperus rotundus L.) TERHADAP TIKUS Sprague Dawley Erni Rustiani; Min Rahminiwati; Tia Mutiara
EKOLOGIA Vol 17, No 2 (2017): JURNAL ILMIAH ILMU DASAR DAN LINGKUNGAN HIDUP
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (404.736 KB) | DOI: 10.33751/ekol.v17i2.762

Abstract

The aim of this study is to compare the potential of ethanolic and water extracted of teki grasstuber on white male rat strain Sprague Dawley at two months of age and 200 g of body weight. The rats were divided among four groups. Each group consists of six rats. The groupswere ethanolic and water extracted of teki grass tuber, positive control group (Paracetamol) and a negative control group (distilled water). Analgesic potency was tested by inducing pain stimuli previously to the animals, in the form of heat stimuli by putting it ona hot plate with the temperature of 55C. The responses of rats observed were licking and moving or lifting of their legs. Observations were made for 1 minute, before and after administration of pain stimulus at 15, 30, 45 and 60 minute. The results showed that ethanol and water extract at an effective dose of 49 mg / 200 g of BW, gave relatively the same effect as an analgesic or positive control group.Keywords : analgesic, ethanol and water extract of teki grass tuber, pain
EFEKTIVITAS KOMBINASI EKSTRAK DAUN MENGKUDU (Morinda citrifolia ) dan ASAM KANDIS SEBAGAI PENURUN BERAT BADAN PADA TIKUS PUTIH JANTAN GALUR Sprague-Dawley Shinta Suci Anggraena; Min Rahminiwati; E. Mulyati Effendi
EKOLOGIA Vol 17, No 1 (2017): JURNAL ILMIAH ILMU DASAR DAN LINGKUNGAN HIDUP
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.354 KB) | DOI: 10.33751/ekol.v17i1.810

Abstract

This study aimed to determine the effect of a combination of extracts of Noni leaves (Morinda citrifolia L) and fruit kandis (Garcinia cowa Roxb) on body weight of male rats induced by high- fat calories food Test animals were used 25 rats male Sprague Dawley strain age of 2 months with body weight 200 g. White mice were divided into 5 groups of 4 rats each. The treatment committed agains an obesity rats. The treatment group consisted of rats doses of 1 (8,75mg/kgBB noni leaves ekstract and sour fruit kandis 7mg/kgBB), dose II (4,75 mg/kgBB noni leaves ekstract and sour fruit kandis 3,5mg/kgBB), dose III (17,5 mg/kgBB noni leaves ekstract and sour fruit kandis 14mg/kgBB), the positive control group were given Orlistat and negative group were only given food to eat and drink. The observed parameters include weight loss, abdominal width, body length, skin fold, body mass indeks. The results showed that noni leaf extract and fruit kandis can be used as a weight loss with the most effective dose is 17,5 mg /kg BB noni leaf + 14 mg/kg BB fruit kandis with the most effective treatment is 14 days.Key words : Noni Leaf and fruit kandis, Feeding a High-Fat Calories, Obesity Parameters, Rats male Sprague Dawley.
Potensi Ekstrak Rimpang Kunyit Sebagai Prebiotik Pemacu Pertumbuhan Lactobacillus plantarum Secara In Vitro MIN RAHMINIWATI; SAEPUDIN RAHMATULLAH; IRMANIDA BATUBARA; SUMINAR S. ACHMADI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 12 No 1 (2014): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (447.774 KB)

Abstract

Turmeric contains curcumin which has antibacterial and anti-inflammatory activities. In addition, turmeric contain also carbohydrates that has potency as a prebiotic agent. Research on turmeric extract that was obtained by maceration in variety of solvent, temperatures and time have been carried out to get the most potent prebiotic extract of turmeric to stimulate L. plantarum growth. Maceration with water at 28oC for 1 hour resulted in extract which can enhance the growth of L. plantarum approximately is higher than controls at a concentration of 1 ppm. L. plantarum growth rate increases with increasing concentration of extract. Sugars content of oligosaccharide in the extract were stakiosa, sucrose and lactose of 3014, 164, and 82 ppm respectively. It is concluded that oligosaccharide in turmeric extract is potential as prebiotic agent to increase L. plantarum growth.
Preventing NSAID-induced Gastropathy: The Role of Mucus Cells to Prevent Aspirin-Induced Acute Gastric Mucosal Damage Chudahman Manan; Bambang Pontjo Priosoeryanto; Daldiyono Daldiyono; Sri Estuningsih; Min Rahminiwati
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 3, December 2011
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (746.141 KB) | DOI: 10.24871/1232011164-167

Abstract

Background: Mucus is pre-epithelial gastric layer that may prevent damages due to direct contact between aspirin and gastric epithelial cells. The integrity of gastric mucosa and mucous cellular reaction may serve as primary and secondary prevention of extended aspirin-induced gastric mucosal damage. The aim of this study was to prove the function of mucus as defensive factor in rats. Method: The study was conducted in twenty white rats of the Sprague-Dawley strain at Department of Pathology and Clinical Reproduction, Bogor Agricultural University, between January and December 2008. The rat in the treatment group were given 400 mg aspirin diluted in aqua bidest through intra- gatric canules; while the control group received aqua bidest only once daily for 3 days. Necropsies, macroscopic and microscopic observation were performed by counting the number of Alcian blue- periodic acid Schiff-stained mucous cells at fundus/corpus and antrum/pylorus regions. Data analysis was performed using ANOVA and Duncan test. Results: The number of mucous cells with positive lesions in the treatment group was significantly different from the control group at both regions. There was no significant difference of negative lesions between treatment and control group at both regions. At antrum/pylorus region, there was no difference of negative lesions between treatment and control groups; however, both groups demonstrated significant difference of positive lesions in treatment group. Conclusion: In primary prevention for gastric mucosal lesions, there is no increasing number of mucous cells in normal mucosa. Increasing number of mucous cells is a secondary prevention against extended aspirin-induced gastric mucosal damage. Keywords: NSAIDs/ASA, mucus cells, gastric mucosal lesion, rat
Dyspepsia in Nonsteroidal Anti-inflammatory Drugs Gastropathy Chudahman Manan; Bambang Pontjo Priosoeryanto; Daldiyono Daldiyono; Sri Estuningsih; Min Rahminiwati
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 2, August 2011
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (692.777 KB) | DOI: 10.24871/1222011100-103

Abstract

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) gastropathy is a common complication, which has characteristic symptoms of dyspepsia syndrome. Mostly, it includes epigastric discomfort with bloating and nausea. The aim of this study was to provide evidences that clinical symptoms of dyspepsia are related to macroscopic changes of gastric form in rats, which are expected to be applied in human. Method: The study was conducted in 20 white rats (Rattus norvegicus, Sprague-Dawley strain) at the Department of Pathology and Clinical Reproduction, Bogor Agricultural University between January and December 2008. The rats were divided to treatment group and control group and each group consisted of 10 rats. Acetyl salicylic acid (ASA/aspirin) was administered at 400 mg dose, diluted in distilled water and was given to the treatment group using gastric cannula, once daily for three days period; while the control group had received aquabidest only. Subsequently, necropsies were conducted for both groups, followed by macroscopic observation and measurement of sagittal and transversal diameter. Gastric incisions along the minor curvature were performed in both groups to recognize any macroscopic changes of gastric mucosa. ANOVA test was utilized for data analysis, which was followed by Duncan test when the results were significant. Results: Gastric diameters in treatment group with positive lesion were significantly different from the control group and the treatment group with negative lesion on anthrum/pylorus region, with p 0.05. Conclusion: Prominent gastric dilatation at anthrum/pylorus region found in the treatment group may become the initial cause and signs of dyspepsia in human. Keywords: NSAID gastropathy, dyspepsia, NSAIDs/aspirin, gastric dilatation
Combination of Nigella sativa and Phyllanthus niruri as An Immunostimulant for The Prevention of White Spot Disease in Litopenaeus vannamei Wida Lesmanawati; Wasmen Manalu; Min Rahminiwati; Muhammad Agus Suprayudi; Sri Nuryati
Journal of Aquaculture and Fish Health Vol. 11 No. 3 (2022): JAFH Vol. 11 No. 3 September 2022
Publisher : Department of Aquaculture

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jafh.v11i3.27470

Abstract

Pacific whiteleg shrimp (Litopenaeus vannamei) is a very important commodity, which accounts for almost 70% of the total world shrimp production. However, this production is still threatened by disease attacks, one of which is caused by white spot disease (WSD). Herbs are widely used as immunostimulants as an effort to prevent diseases. Black cumin (Nigella sativa) and stone breaker (Phyllanthus niruri) have long been known as excellent immunostimulants in human. This study aimed to evaluate the potential of N. sativa and its combination with P. niruri as an immunostimulant in L. vannamei for preventing WSD. Tested shrimp (±3.0 g) were treated by N. sativa (N), P. niruri (P) and the combination of both (1N:1P, 2/3N:1/3P, 3/4N:1/4P, 1/3N:2/3, 3/5N:2/5P, 1/4N: 3/4P, 2/5N:3/5P) through feed for 28 days. They were then infected by white spot syndrome virus (WSSV) and observed for 7 days. The parameters observed included immune response and production performance.  N. sativa was able to reduce the mortality of test shrimp infected with WSSV, with an RPS value of 71%. N. sativa can be combined with P. niruri in the right composition (1/2N:1/2P and 2/3N:1/3P), while the other combinations are antagonistic. The administration of the best treatments in this study, relatively did not affect the value of total hemocyte count, phenoloxidase activity, respiratory burst activity, hemolymph clotting time and production performance of tested shrimp.
Co-Authors , Triadiati . andriyanto . Soeripto A.S. Satyaningtijas Achmad Tjahja Ade Sunarma Ade Sunarma Adi Riyadhi Agik Suprayogi Agus Setiyono Ahmad Subhan Ahmad Tjahja Nugraha, Ahmad Tjahja Amrozi Andriyanto . Andriyanto A Anggraena, Shinta Suci Ani Murtisari April Hari Wardhana Arief Boediono Aryani Satyaningtijas Aswani, Tuti Aulia Andi Mustika Bambang Pontjo Priosoeryanto Budi Wirawan Cantika Zaddana Ceristianto Ceristianto Ceristianto, Ceristianto Chudahman Manan Chudahman Manan Daldiyono Daldiyono Daldiyono Daldiyono Damiana Rita Ekastuti Dede Sukandar Deni Noviana Djumali Mangunwidjaja Dyah Iswantini E Mulyati Effendi, E Mulyati Erni Rustiani Fadillah, Wendi Nurul Fajar Triansyah Gumelar Firman, Gelline Tama Anindia Fitri Dwiputri Franco, Christopher MM Gelline Tama Anindia Firman Gumelar, Fajar Triansyah Hajar Hajar Hambarsika, IGM Antara HANDAJANI, FITRI Huda Shalahudin Darusman IETJE WIENTARSIH Ika Amalia, Ika Ike Yulia Wiendarlina Irmanida Batubara Ita Djuwita Ita Juwita Joshie Ramadhan Juwita, Ita Kusdiantoro Mohamad La Ode Sumarlin La Ode Sumarlin latifah K Darusman latifah K Darusman Latifah Kosim Darusman Lina Novianti Sutardi Livana Dethris Rawung Lusi Indriani M. Agung Zaim Adzkiya M. Zairin Junior Mahyuni, Siti Martha Arofa Dilla Mashuri Waite Meyliana Wulandari MUHAMMAD AGUS SUPRAYUDI Murtisari, Ani Mutiara, Tia Najwa Rokhmah, Nisa Nampiah Sukarno Neni Nuryani Nhestricia, Nhadira Novriyandi Hanif Oom Komala Rahmania Hanim Rahmat Hidayat Raudhatul Jannah Rosihan Rosman SAEPUDIN RAHMATULLAH Sara Nurmala Shinta Suci Anggraena Sholehah, Akipah Nazla Siti Saadah Siti Sa’diah Sri Budiarti Poerwanto Sri Estuningsih Sri Nuryati Suci Sintya Sulistyaningsih, Yohana Caecilia SUMINAR S. ACHMADI Supardi, Arviani Rahmawati Tia Mutiara Tiyan Hidayanti Tuti Aswani Ulandari, Rafika Unang P. Unang Patriana Upik Kesumawati Hadi Waite, Mashuri Wasmen Manalu Wei Zhang Wendi Nurul Fadillah Wida Lesmanawati Widia Safitri Yasinta Ratna Esti Wulandari Yohana Caecilia Sulistyaningsih YULIN LESTARI Zaenal Abidin