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Slamet
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Journal : CERATA

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Uji Aktivitas Anti Inflamasi Ekstrak n-Heksan, Etil Asetat dan Etanol Daun Kecombrang (Etlingera Elatior) Pada Tikus Putih Jantan Galur Wistar (Rattus Norvegiucus) Alfanda, Dea; Slamet; Sigit Prasojo
CERATA Jurnal Ilmu Farmasi Vol 12 No 1 (2021): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v12i1.191

Abstract

Kecombrang (Etlingera elatior) is one of the Indonesian herbal plants, frequently used by our society as anti-inflammation. This medicine has a function to reduce infection. This study aims to examine the activity of ani-inflammation from the extract of n-hexan, ethyl acetate, and ethanol of kecombrang (Etlingera elatior) leaves. It useá experimental as a method by using inflammation inhibition test on the tested white male mouse of galur wisiar as sampie. This sample is divided into 6 groups and each was given at a dose at 50 mg/kgweight, 100 mg/KGBW, 150 mg/KGBW, and 200 mg/K.gBW. Besides, for the positive control group, Diclofenac sodium was used at a dose of 4.5 mg / KGBW, which was previously induced by edema with 1% Karangenan. Edema measurenients were carried out every 10 minutes after being induced by carrageenan using a pletismometer. The data result of anti-inflammation activity from each extract has been exainined the differences between test groups with the ANOVA statistical test The result of Tukey statistical test stated ethanol extract of kecombrang leaves at a dose of 200 mg/KGBW has a good anti-inflammation activity, achieving a value of 0.972, 0.994, and 1,000. It means there is no different anong extract of n-hexan, ethyl acetate, and ethanol.
Co-Authors Agus Sulastio Agus Wiranata Agustinus Tamo Bapa Ahmad Muhibbin Ahmad Syauqy Mubarok Ainun Fitri Mughiroh Al-Farisi, Nizar Ahmad Alfanda, Dea Ali Mandan Angelina Anggraini, Maya Lestari Anik Gufron Anita Dewi U Anwari Ari Nuswantoro Arif Setia Sandi A. Asyifa Urohmah, Isma As’ady, Mustofa Atingul Chusna Budi Suhendro Dani Ramdani, Dani Denni Lesmana Dinasti Aprillia Edward Ngii Eka Syahrul Afrian Elfrida Ratnawati Eniya Listiani Dewi Erlin Melani Ety TDC Fadilah Putri, Najah Faizal Rizky Yuttama Fikri Aris Munandar Fitrah Yuliawati Fitri Puji Rahmawati Fitria, Lailatul Grace Maria Fitricia Panggabean Hamdani Hana Salsabila Hanan Izza Hanafi Hendriana, Benny Hery Susanto Indrayati Indrayati Ismil Mubarok Isnan Murdiansyah Istanto, Iwan Jamaliatul B Juhan Syah, Fahmi Kamarza Mulia, Kamarza Karima KHOIRUNNISA Kurnia Al Fandi La Welendo Laili, Afrohatul Lesmana, Denni Lianti Putri, Puspita Lucy Nancy Simatupang Lukman Sholeh M Wildan Purnama M. Makruf Al Arif Manshur, Fauzan Al Mardhatillah Mariana Matsuri Maulidiyah Salim miftah nugroho Miswan Ramdani Mochammad Arifin Mohammad Jusak Mohammad Nurul Huda Muammar Makmur muhammad irfan Muhammad Irfan Muhammad Nufail Yaskur Muis, Ahmad Munajat Munajat, Munajat Nadifa Ariya Maulinda Nailul Falah, Nailul Nina Oktarina Ningrum, Eva Veronika Cahya Nisa, Dea Izatin Nisa, Irma Naza ‘Aina Nu'man, Moh. Nuniek Nizmah Fajriyah Nur Husna Afandi, Alia Nurwijayanti Nuryanti Oktarina, Yetti Oktaviani Adhi Suciptaningsih Pahlewi, Reza Mina Pajri, Ari Purwati Latifah, Linatri Putra, Galih Rangga Ramadhan, Genta RATNAWATI Ria Ester Ridwan Syah Nuhun Riky, Moh. Rini Sriyani Rio Natanael Wijaya Riska Pristiani Rita Arbianti Rokhmat Arifianto Rosidi, Mohammad Rustamadji, Ryan Rafi Rustanto R Saddam Husein, Saddam Samsul Rosadi Santoso, Calvin Sartika, Farahiyah Sartika Setiani Shirly Rizki Kusumaningrum Sianipar, Ronald Sigit Adi Setiawan sigit prasojo Siti Aisyah Soekorini, Noenik Subekti Sudrajat, Umar Suhari Sulaiman , Robi Suryapranata, Bryan Tamo Bapa, Agustinus Tania Surya Utami Teguh Santoso Teguh Sutanto Tiur Elysabeth Tri Gunawan Trianingsih Eni Lestari Triwibowo, Deny Nugroho Tsamara Bunga Maulida Tutut Wurijanto Uus Ruswandi wicaksono, Samsiar Widana, Alit Widiastuti, Eko H Wildan Mahmudin Yanto Maulana Restu Yati, Mirta Dwi Yuswan Muharam