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PROFILE OF RENAL FUNCTION LABORATORY EXAMINATIONS IN PROLANIS PATIENTS IN PONTIANAK CITY Nuswantoro, Ari; Aprillia, Dinasti; Purwaningsih, Indah; Arifah, Rizki Zanuba
Jurnal Laboratorium Khatulistiwa Vol 5, No 2 (2022): Mei 2022
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v5i2.979

Abstract

Diabetes mellitus (DM) and hypertension is one of the chronic diseases that cause health problems in Indonesia. The government organizes a Management Program Chronic Disease (Prolanis) in order to manage patients with both of these diseases. One of the activities carried out is laboratory tests of urea and serum creatinine. This study aims to describe the number of DM and hypertension sufferers as well as serum urea and creatinine levels in Prolanis participants which checked themselves into the Unit Pelaksana Teknis Pusat Laboratorium Kesehatan Kota Pontianak. The study was conducted using a total sampling method by looking at the medical record data of Prolanis participants, who will check themselves to the Unit Pelaksana Teknis Pusat Laboratorium Kesehatan Kota Pontianak, from January – December 2021 so that data were obtained from 333 patients consisting of 84 men and 349 women with an age range of 26 – 91 years. The results showed that 163 patients were diagnosed with DM and the remaining 170 people suffered from hypertension. The average value of urea levels to male patients is 36.4 mg/dL (14 – 113 mg/dL) and to women it is 27.3 mg/dL (11 – 80 mg/dL). The average value of creatinine levels to men is 1.3 mg/dL (0.5 – 5.3 mg/dL) and to women is 0.8 mg/dL (0.4 – 1.9 mg/dL). Urea and creatinine levels are theoretically associated with the incidence of DM and hypertension.
Pengukuran Nilai MPN Pada Air Minum Isi Ulang Di Wilayah Kota Pontianak Yang Disterilisasi Dengan Portabel Ultraviolet Dan Portabel Filtrasi Reza, Nur; Nuswantoro, Ari; Indrawati, Ratih; Muhammad Ihsan, Bagus
Innovative: Journal Of Social Science Research Vol. 3 No. 6 (2023): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Air merupakan kebutuhan utama manusia untuk bertahan hidup sedangkan sumber air bersih alami semakin banyak yang tercemar. Sebagai alternatif, masyarakat mendapatkan air minum dari depot air minum isi ulang (DAMIU) yang menggunakan metode sterilisasi portabel ultraviolet (UV) dan portabel filtrasi. Namun demikian, bakteri coliform masih ditemukan pada air minum karena air baku yang tercemar, alat yang digunakan tidak steril, dan minimnya wawasan masyarakat mengenai sanitasi dan higien DAMIU. Tujuan penelitian ini menghitung nilai most probable number (MPN) pada DAMIU di Kota Pontianak. Penelitian ini berbentuk deskriptif eksploratif berdesain cross-sectional. Data diperoleh dengan melakukan pemeriksaan MPN terhadap 36 sampel DAMIU. Hasil menunjukkan 14 (77,78%) DAMIU metode portabel ultraviolet dan 17 DAMIU (94,44%) portabel filtrasi menunjukkan nilai MPN di atas batas yang ditentukan. Banyaknya DAMIU yang tidak sesuai persyaratan kualitas air minum layak konsumsi sesuai Permenkes menunjukkan adanya risiko penularan penyakit yang disebabkan oleh coliform melalui air minum DAMIU di Kota Pontianak.
POTENSI TEPUNG KULIT PISANG RAJA SEBAGAI MEDIA ALTERNATIF PERTUMBUHAN JAMUR Penicillium sp. Kamilla, Laila; Fadilla, Alda Nur; Nuswantoro, Ari; Tumpuk, Sri
Jurnal Laboratorium Khatulistiwa Vol 8, No 1 (2024): November 2024
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v8i1.1665

Abstract

Sumber karbohidrat yang mudah ditemukan dan belum banyak dimanfaatkan adalah tepung kulit pisang raja. Kulit pisang raja memiliki potensi untuk digunakan sebagai media alternatif karena memiliki kandungan zat seperti karbohidrat, protein, dan lemak. Tujuan penelitian ini untuk mengetahui potensi tepung kulit pisang raja sebagai media pertumbuhan jamur Penicillium sp. Penelitian ini menggunakan desain penelitian Quasi Experiment. Populasi dalam penelitian ini yaitu kulit pisang raja. Sampel yang digunakan adalah tepung kulit pisang raja yang dibuat dalam konsentrasi 10%, 20%, 30%, 40%, 50% dengan 5 kali pengulangan didapatkan jumlah sampel 25. Hasil penelitian yaitu konsentrasi 10% rata- rata 11,6 CFU, konsentrasi 20% rata-rata 12,8 CFU, konsentrasi 30% rata-rata 17,4 CFU, konsentrasi 40% rata-rata 21,8 CFU, konsentrasi 50% rata-rata 28 CFU dan media standar Sabouraud Dextrose Agar (SDA) koloni diperoleh rata-rata 152,6 CFU. Hasil uji Anova didapatkan nilai 0,000 < 0,05 yang menyatakan ada perbedaan pertumbuhan jumlah koloni pada tiap konsentrasi media alternatif dengan media standar Sabouraud Dextrose Agar (SDA) dapat disimpulkan media alternatif tepung kulit pisang raja berpotensi digunakan sebagai media pertumbuhan jamur Penicillium sp. namun tidak dapat menggantikan media standar Sabouraud Dextrose Agar (SDA).
Number of Bacterial Colonies After Washing Hands with Antiseptic Soap and Regular Soap: A Study on Department of Health Analyst Students in Poltekkes Kemenkes Pontianak Nuswantoro, Ari; Salim, Maulidiyah; Slamet; Dinasti Aprillia
Jurnal teknologi Kesehatan Borneo Vol 1 No 2 (2020): Jurnal Teknologi Kesehatan Borneo
Publisher : POLTEKKES KEMENKES PONTIANAK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jtkb.v1i2.27

Abstract

Hand washing is a healthy activity carried out by many parties. Getting used to wash your hands properly will increase health. The soap on the market is plain hand washing soap and antiseptic handwashing soap. The second type is claimed to be more effective in reducing the amount of bacterial contamination than plain soap because it contains antimicrobial ingredients to increase product sales. This study aims to determine the differences in the number of bacterial colonies on the palms of students who wash their hands with antiseptic soap and plain soap among students of Analyst Department of Pontianak Health Polytechnic, Minister of Health. This research was quasi-experimental, with 24 respondents. Each respondent was asked to wash hands properly twice, the first with plain soap that does not contain an antiseptic (A) and the second with soap containing antiseptic (B). After examining the number of bacteria on the respondent’s thumb, the average number of bacterial colonies got in treatments A and B was 45,5 and 38,8 CFU, respectively. Mann-Whitney U statistical test results got a probability value of 0.391> 0.05, which means there is no difference in the number of bacterial colonies in the palms that washing hands with plain soap and with antiseptic soap. This study revealed the fact that the number of bacterial colonies in the group that washed hands with antiseptic soap was lower than those who washed their hands with ordinary soap.
Potential of Methanol Extract of Bungli Fruit Seed (Oroxylum Indicum) in Inhibiting the Growth of Escherichia coli Nuswantoro, Ari; Natasya Intan Ramadhani
Jurnal teknologi Kesehatan Borneo Vol 2 No 1 (2021): Jurnal Teknologi Kesehatan Borneo
Publisher : POLTEKKES KEMENKES PONTIANAK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jtkb.v2i1.29

Abstract

Bungli (Oroxylum indicum) has been used for generations in Asia as traditional medicine. The seeds of the bungli are commonly used as traditional medicine to treat typhoid, cough, hypertension, internal fever, fever and diarrhea. The active compounds in this plant are known to have anti-inflammatory, antirheumatic, antifungal and antibacterial activities. Our research on methanol extract of bungli fruit seeds showed its potential to inhibit the growth of Escherichia coli bacteria that causes diarrhea. Bungli seed extract samples with a concentration of 25% showed an inhibition zone with a diameter of 9.22 mm, while at a concentration of 50% the diameter was 11.16 mm and 75% had a diameter of 12.88 mm. This size is indeed smaller than chloramphenicol (26 mm), but this potential can be greater if the extraction is carried out more intensively to extract the active compound, the sample concentration is increased, and the part or age of the plant with the highest content of the active compound is used; so that the Bungli plant is expected to be an alternative in overcoming Escherichia coli infection.
PERBEDAAN HASIL HITUNG BERBAGAI JENIS LEUKOSIT PADA PASIEN COVID-19 YANG ISOLASI MANDIRI DENGAN ISOLASI DI RSUD KABUPATEN MELAWI Reza, Nur; Santoso, Edi; Nuswantoro, Ari; Indrawati, Ratih; Nurhayati, Etiek; Aditia, Aditia
Media Penelitian dan Pengembangan Kesehatan Vol. 32 No. 3 (2022): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v32i3.1886

Abstract

COVID-19 infection causes various clinical manifestations so the treatment method is also different for each individual. Patient isolation is one of the treatments to break the chain of transmission of COVID-19. Asymptomatic to moderate symptomatic patients are usually asked to self-isolate, while those with severe and critical symptoms are isolated in hospital. Leukocyte examination is an important parameter and plays a role in determining patient follow-up. The aim of this study was to find out whether there were differences in leukocyte differential-counts in COVID-19 patients who were self-isolating and those isolated at Melawi Regional Hospital. This study had a cross-sectional design by taking data from medical records of COVID-19 patients at Melawi Regional Hospital during October 2021 to July 2022. The data taken were from 399 COVID-19 patients, consisting of 182 patients are self-isolating and 217 patients are isolating at Melawi Regional Hospital. In self-isolated patients, the average value of leukocyte count was 7.04 x 10³ cells/µL, and the leukocyte differential-counts was neutrophils 58.45%, lymphocytes 21.81%, monocytes 13.84%, eosinophils 1.52%, and basophils 4.38%. In isolated patients at Melawi Regional Hospital, the average value of leukocyte count was 9.89 x 10³ cells/µL, and the leukocyte differential-counts was neutrophils 75.09%, lymphocytes 12.97%, monocytes 8.38%, eosinophils 0.46%, and basophils 3.11%. The Mann-Whitney U test obtained a significance value of 0.000 (p < 0.05), which means there is a significant difference in the results of leukocyte counts between self-isolated patients and those isolated at Melawi Regional Hospital.
KAJIAN TENTANG PENURUNAN JUMLAH DONOR DARAH AKIBAT PANDEMI COVID-19: DATA SELAMA 4 TAHUN DARI UDD PMI KOTA PONTIANAK Aditia, Aditia; Samwidya, Veronika Sriayu; Nuswantoro, Ari; Djohan, Herlinda; Supriyanto, Supriyanto; Reza, Nur
Media Penelitian dan Pengembangan Kesehatan Vol. 32 No. 4 (2022): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v32i4.1890

Abstract

The COVID-19 pandemic has left a noticeable mark on the health care sector. One such example is the blood services provided by the Blood Donor Unit (UDD) of Indonesian Red Cross (PMI). Every time there was an increase in COVID-19 cases, blood donation activities sharply decreased, according to the UDD PMI. During the COVID-19 pandemic, there was a scarcity of blood donors. This research aimed to see the difference in the number of blood donors before and during the pandemic. This research was descriptive analytical with a cross-sectional design by collecting data on the number of blood donors at UDD PMI Pontianak City from 2018 to 2022. The results of the study show that the number of blood donors before the pandemic was 52,607 donors, while the number of blood donors during the pandemic was 48,421 donors. which means there was a decrease in the number of blood donors by 4,186 donors (7.96%). The Independent Samples Test obtained a significant value of 0.045 (p < 0.05), which means there was a difference in the number of blood donors before and during the COVID-19 pandemic at UDD PMI Pontianak City. Concerns about the risk of infection and government policies limiting activities outside the home can explain why the COVID-19 pandemic has resulted in a decline in blood donation rates.
KORELASI KADAR C-REACTIVE PROTEIN DENGAN JUMLAH TROMBOSIT PADA PENDERITA DIABETES MELITUS TIPE 2 Nuswantoro, Ari; Wicaksono, Didik; Aditia, Aditia
Media Penelitian dan Pengembangan Kesehatan Vol. 33 No. 2 (2023): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v33i2.1903

Abstract

Type 2 diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia and insulin resistance, associated with decreased nitric oxide (NO) levels, increased free radical production, inflammation, endothelial dysfunction, and progressive vascular damage. C-reactive protein (CRP), an acute phase protein regulated by pro-inflammatory cytokines like interleukin-6 (IL-6), serves as a systemic inflammation marker. Pentameric CRP (pCRP) and monomeric CRP (mCRP) are implicated in mediating inflammation and endothelial dysfunction, with roles in endothelial cell adhesion, phagocytosis, inflammatory signaling, and interactions with endothelial cells, neutrophils, macrophages, and platelets. Additionally, leukocytes secrete platelet-activating factors, enhancing platelet activation and cytokine and chemokine release. This descriptive analytical study with a cross-sectional design aimed to investigate the correlation between CRP levels and platelet counts in patients with type 2 DM. Utilizing purposive sampling, 47 patients diagnosed with DM at Sultan Syarif Mohamad Alkadrie Hospital, Pontianak, during June 2023 were selected. CRP levels were measured using the fluorescence immunoassay (FIA) method, while platelet counts were determined through the impedance method. Statistical analysis employing Kendall's Tau-b test revealed a significant correlation (p < 0.05, r = -0.508), indicating that elevated CRP levels are significantly associated with reduced platelet counts in type 2 DM patients.
EFEKTIVITAS MENGONSUMSI OBAT ANTIRETROVIRAL DALAM MENURUNKAN ANGKA VIRAL LOAD PADA ODHA Fahrani, Chantika Lailatussa'adah; Romadi, Romadi; Nuswantoro, Ari; Wahdaniah, Wahdaniah; Aditia, Aditia
Media Penelitian dan Pengembangan Kesehatan Vol. 33 No. 1 (2023): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v33i1.1934

Abstract

Human Immunodeficiency Virus (HIV) has infected many people throughout the world. In Indonesia alone, around 540,000 people have been infected with HIV and are living with Acquired Immunodeficiency Syndrome (AIDS). Until now, antiretroviral drug therapy (ARV) is the best choice which aims to reduce the risk of transmission, prevent worsening due to opportunistic infections, improve the quality of life of sufferers, and reduce the amount of virus (viral load) in the blood until it is undetectable. The aim of this study was to explain the effectiveness of taking ARV drugs in reducing viral load rates in patients at the Tulipe Clinic, M. Th. Hospital. Djaman, Sanggau Regency. This is a non-experimental quantitative research with a cross-sectional design. Sampling technique using purposive sampling, with the criteria applied, namely that respondents are ODHA or patients who have been diagnosed with HIV/AIDS, have undergone ARV therapy for at least six months, and are willing to become respondents so that a total of 89 people during 2022 – 2023 were obtained. The results of the study showed that the duration of taking ARVs ranged from 6 to 98 months, the viral load number was 14 - 35,400 copies/ml. The Spearman test obtained a significance value of 0.000 (p < 0.05), which means that taking ARV medication is effective in reducing viral load rates in Tulipe Clinic patients at M. Th. Hospital. Djaman, Sanggau Regency. Based on the results, it is expected that future studies can measure viral load along with molecular immunological parameters such as cytokine and antibody levels.
HUBUNGAN KADAR C-REACTIVE PROTEIN DENGAN DERAJAT KEPARAHAN PASIEN COVID-19 YANG DIRAWAT INAP DI RUMAH SAKIT Nuswantoro, Ari; Perdede, Lusi Hernawati; Aulia, Annisa Syafa; Aditia, Aditia
Media Penelitian dan Pengembangan Kesehatan Vol. 32 No. 4 (2022): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v32i4.2026

Abstract

Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) can appear with a varied clinical spectrum, ranging from no symptoms, mild illness, moderate illness, to severe illness. The high mortality rate is closely related to the severity of the disease. One of the laboratory parameters that is thought to be related to the severity of COVID-19 is C-Reactive Protein (CRP). This study aimed to determine the relationship between CRP values and the severity of COVID-19 patients. This research has an analytical observational design with a cross-sectional approach. The samples were COVID-19 patients with moderate and severe symptoms who were hospitalized at RSUD dr. Soedarso West Kalimantan in January - December 2021. The sampling technique was total sampling to obtain medical record data which included CRP values and patient severity levels so that 49 data were obtained. The results showed that 8 respondents (16.3%) had CRP levels of 0.8 mg/dL, 24 respondents (49%) had CRP levels of 1.6 mg/dL, 9 respondents (18.4%) had CRP levels of 3 .2 mg/dL and 8 respondents (16.3%) had CRP levels of 6.4 mg/dL. Based on Kendall's tau-b statistical test, a significance value of 0.001 <0.05 was obtained, which means there is a significant relationship between CRP levels and severity. The correlation coefficient value of 0.708 shows a strong correlation coefficient between CRP levels and severity. This proves that the higher the CRP levels of COVID-19 patients found, the more severe the degree of disease that may be suffered by these patients, so there is a close relationship between CRP levels and the degree of disease of COVID-19 patients.
Co-Authors Adawiyah, Rabi’atul Aditia Aditia Aditia, Aditia Aditiya Ramadan Affifatuzahara Affifatuzahara Anisya Nur Shafitri Ardhani, Adha Riesta Arifah, Rizki Zanuba Astuti, Fitri Mega Aufani, Destia Aulia, Annisa Syafa Azura azura Azzahra, Larasabella Bagus Muhammad Ihsan Benedikta Anjelica Desi Wahyumarniasari Devi Nurfitri Bintang Dinasti Aprilia Dinasti Aprillia Djohan, Herlinda Edi Santoso Emilda Sari Fadilla, Alda Nur Fahma Ajeng Al-qorifah Fahrani, Chantika Lailatussa'adah Fitra Fathuhudin Grovindo Grovindo Hartati, Fitri Ulya Herlinda Djohan Imma Fatayati Indah Purwaningsih Indah Purwaningsih Indrawati, Ratih Jenny Ratnawati, Gervacia Jessica Ningtyas Berlianti Jordan, Aristo Juliana Cristyaningsih Kartini Kartini Laila Kamilla Laila Kamilla Linda Triana Linda Triana Linda Triana Liza Harum Nur Annisa Maretalinia Maretalinia Maretalinia, Maretalinia Maulidiyah Salim Merda Sri Rahayu Monalita, Ria Muhammad Ihsan, Bagus Munardi, Fhatia Natasya Natasya Intan Ramadhani Nurhayati, Etiek Nurul Uq'ma P Purwanto Panyada Cholsakhon Perdede, Lusi Hernawati Rahayu, Merda Sri Ramadan, Aditiya Ratnawaty, Gervacia Jenny Reza Setiawan Reza, Nur Rezky, Muhammad Andyka Riska Alfianita Rizki Zanuba Arifah Romadi Romadi Sadid, Randy Samwidya, Veronika Sriayu Sharen Sen Slamet Sri Tumpuk Sugito Sugito Sugito Sugito Supriyanto Supriyanto Supriyanto Supriyanto Sutriswanto Sutriswanto Suwandi, Edy Syahdilla, Ade Syopingi Syopingi Syopingi, Syopingi Tantri Rahmatika Tarisya Fitri Pratiwi Theresia Indah Budhy Sulisetyawati Tika, Dian Tumpuk, Sri Veny Veny Wahdaniah Wahyudi Wicaksono, Didik Yunus, Mohd