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Normal dan Dislipidemia: Profil Lipid Pasien Hipertensi- Prolanis di Kota Pontianak Sen, Sharen; Nuswantoro, Ari; Kamilla, Laila; Aprilia, Dinasti
MAHESA : Malahayati Health Student Journal Vol 4, No 1 (2024): Volume 4 Nomor 1 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i1.13266

Abstract

ABSTRACT The primary cause of cardiovascular disease (CVD) is hypertension (HT). Through the Prolanis program, BPJS treats HT patients in Indonesia through various activities, including physical activity and monitoring lipid profiles, which until now have not been widely reported. The aim of this study was to describe the lipid profile of HT patients participating in Prolanis in Pontianak City. The samples are the medical records from 110 patients chosen using the total sampling method in 2022 at the Unit Pelaksana Teknis Pusat Laboratorium Kesehatan Kota Pontianak. Information gathered from 99 women and 11 men revealed that 80.8% of the women had hypercholesterolemia; triglycerides and HDL were mainly within normal ranges; LDL ranged from normal (13.6%) to extremely high (8.2%); and the ratios of cholesterol to HDL and triglycerides to HDL were mainly normal. One of the Prolanis program's goals, physical exercise, appears to have an impact on the patient's typical lipid profile. Nonetheless, the fact that some people have dyslipidemia raises awareness of the risk of CVD and supports the necessity of keeping this program in place. Keywords: Cardiovascular Disease, Lipid Profile, Hypertensive Patients, Prolanis  ABSTRAK Penyebab utama penyakit kardiovaskular (CVD) adalah hipertensi (HT). Melalui program Prolanis, BPJS menangani pasien HT di Indonesia melalui berbagai kegiatan, termasuk aktivitas fisik dan pemantauan profil lipid, yang hingga saat ini belum banyak dilaporkan. Tujuan dari penelitian ini adalah untuk mendeskripsikan profil lipid pasien HT yang mengikuti Prolanis di Kota Pontianak. Sampel penelitian ini adalah rekam medis dari 110 pasien yang dipilih dengan menggunakan metode total sampling pada tahun 2022 di Unit Pelaksana Teknis Pusat Laboratorium Kesehatan Kota Pontianak. Informasi yang dikumpulkan dari 99 wanita dan 11 pria menunjukkan bahwa 80,8% wanita mengalami hiperkolesterolemia; trigliserida dan HDL sebagian besar dalam kisaran normal; LDL berkisar dari normal (13,6%) hingga sangat tinggi (8,2%); dan rasio kolesterol terhadap HDL serta trigliserida terhadap HDL sebagian besar dalam kisaran normal. Salah satu tujuan program Prolanis, yaitu latihan fisik, tampaknya berdampak pada profil lipid pasien. Meskipun demikian, fakta bahwa beberapa orang memiliki dislipidemia meningkatkan kesadaran akan risiko CVD dan mendukung perlunya mempertahankan program ini. Kata Kunci: Penyakit Kardiovaskular, Profil Lipid, Pasien Hipertensi, Prolanis
IDENTIFIKASI DAN PROFIL RESISTENSI BAKTERI PADA MINUMAN AIR TAHU DAN AIR TEBU DI WILAYAH KOTA PONTIANAK Aditia, Aditia; Nuswantoro, Ari; Djohan, Herlinda; Ihsan, Bagus Muhammad; Uq'ma, Nurul; Shafitri, Anisya Nur; Affifatuzahara, Affifatuzahara; Al-qorifah, Fahma Ajeng; Anjelica, Benedikta
Jurnal Ilmiah Global Education Vol. 4 No. 4 (2023): JURNAL ILMIAH GLOBAL EDUCATION, Volume 4 Nomor 4, Desember 2023
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/jige.v4i4.1860

Abstract

Tofu and sugarcane juice drinks are in great demand because they taste delicious and affordable. These drinks can be contaminated with pathogenic bacteria due to hygiene and poor environment. Contamination of pathogenic bacteria that are resistant to antibiotics is a serious health threat.  The objective of this study is to identify and provide antibiotic resistance bacteria from tofu and sugarcane juice drinks overview. This Study is a descriptive-observation with a cross-sectional design. Bacterial identification is carried out by culture, while resistance testing is carried out by Kirby-Bauer. Penicillin, amoxicillin, ampicillin, ciprofloxacin, chloramphenicol, gentamicin, tetracycline, and vancomycin were used. 43 samples of tofu water drink and 70 samples of sugarcane juice drink were selected by purposive sampling. Staphylococcus aureus, Salmonella typhi, Enterobacter aerogenes, and Klebsiella pneumoniae founds in tofu drinks, while Enterobacter aerogenes, Salmonella typhi, Shigella dysenteriae, and Escherichia coli founds in sugarcane juice. Staphylococcus aureus resistant to penicillin (100%), Salmonella typhi resistant to penicillin (66.6%), Enterobacter aerogenes resistant to tetracycline (70%), Klebsiella pneumoniae resistant to penicillin (100%), Shigella dysenteriae resistant to ampicillin and gentamicin (100%), and Escherichia coli resistant to vancomycin (100%). Pathogenic-resistant bacteria in tofu and sugarcane juice drinks show the risk of spreading resistant bacteria which can trigger bacterial resistance with a wider spectrum.
PROFIL LIPID SEBAGAI PREDIKTOR UREUM DAN KREATININ PADA PASIEN PROLANIS PENDERITA DMT2 DI UPT PUSAT LABKES KOTA PONTIANAK Pratiwi, Tarisya Fitri; Fatayati, Imma; Supriyanto, Supriyanto; Nuswantoro, Ari; Aprillia, Dinasti
Jurnal Review Pendidikan dan Pengajaran Vol. 7 No. 4 (2024): Vol. 7 No. 4 Tahun 2024
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jrpp.v7i4.33968

Abstract

Lebih dari 1 miliar orang diperkirakan akan menderita diabetes melitus (DM) pada tahun 2050. Keadaan dislipidemia akibat DM menaikkan risiko inisiasi komplikasi nefropati diabetik. Dislipidemia memiliki dampak tidak langsung terhadap penurunan fungsi ginjal karena dapat menyebabkan aterosklerosis, yang membuat ginjal bekerja lebih keras untuk menyaring darah dari waktu ke waktu. Tujuan penelitian ini adalah untuk mengetahui apakah profil lipid berhubungan dengan ureum dan kreatinin sebagai parameter fungsi ginjal pada pasien prolanis penderita DMT 2 yang terdaftar di Unit Pelaksana Teknis (UPT) Pusat Laboratorium Kesehatan Kota Pontianak. Penelitian ini berbentuk deskriptif dan berdesain cross-sectional dengan menggunakan data sekunder rekam medis pasien periode Januari 2023 sampai dengan Desember 2023 pasien prolanis penderita DMT 2 yang terdaftar di UPT Pusat Laboratorium Kesehatan Kota Pontianak yang dipilih menggunakan teknik purposive sampling, dengan kriteria yang diberlakukan yaitu pasien prolanis penderita DMT 2 yang melakukan pemeriksaan kolesterol total, trigliserida, HDL, LDL, ureum dan kreatinin dan terdaftar di UPT Pusat Laboratorium Kesehatan Kota Pontianak sehingga didapatkan 339 responden. Analisis statistik dengan uji Kendall’s Tau-b menunjukkan kadar HDL berhubungan dengan kadar ureum dan kadar kreatinin dengan nilai signifikansi berturut-turut adalah 0,035 (p <0,05) dan 0,001 (p < 0,01). Serta didapatkan nilai koefisien korelasi berturut-turut adalah r = -0,078 dan -0,123 yang artinya semakin rendah kadar HDL maka semakin tinggi kadar ureum dan kadar kreatinin pasien tersebut.
The Relationship Between Premature Rupture of Membranes (PROM) and Leukocyte Levels in Newborns Grovindo Grovindo; Sutriswanto Sutriswanto; Ari Nuswantoro; Panyada Cholsakhon
MEDICA (International Medical Scientific Journal) Vol. 7 No. 1 (2025): MEDICA (International Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v7i1.484

Abstract

Premature Rupture of Membranes (PROM) remains a global concern in obstetrics due to its potential to cause complications such as infections that increase maternal and neonatal morbidity and mortality. PROM occurs in approximately 10–15% of pregnancies worldwide and 8–10% in Indonesia, often before 37 weeks of gestation, contributing significantly to preterm births and neonatal deaths. Risk factors for PROM include maternal age, parity, infection, and other pregnancy-related conditions. Infection resulting from PROM can be identified through leukocyte count in newborns, with leukocytosis indicating the presence of infection. This study aimed to examine the relationship between PROM and leukocyte levels in newborns at RSUD Drs. Jacobus Luna, M.Si, Bengkayang Regency, using a descriptive-analytic design with a cross-sectional approach and total sampling of 88 respondents. Results showed that among 36 newborns with elevated leukocyte levels, 28 cases (77.8%) were born from PROM pregnancies, whereas only 8 cases (22.2%) were non-PROM. Among 52 cases with normal leukocyte levels, only 11 newborns (21.2%) had PROM, while 41 (78.8%) did not. These findings indicate that newborns from PROM pregnancies tend to have higher leukocyte counts. Statistical analysis using Chi-square showed a significant relationship between PROM and leukocyte levels, with a p-value of 0.000 (< 0.05). In conclusion, PROM is a notable risk factor for increased leukocyte counts in neonates, underscoring the importance of early detection and management of PROM to reduce the risk of neonatal infection and its associated complications.
The Antibacterial Effectiveness of Moringa Oleifera Leaves Extract Against the Growth of Escherichia coli Using the Diffusion Method Liza Harum Nur Annisa; Linda Triana; Emilda Sari; Ari Nuswantoro
MEDICA (International Medical Scientific Journal) Vol. 6 No. 3 (2024): MEDICA (International Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v6i3.487

Abstract

Moringa oleifera leaves a common herbal plant found in tropical regions and naturalized in Indonesia, are known to be rich in bioactive compounds such as flavonoids, tannins, terpenoids, alkaloids, and saponins. These compounds have potential medicinal properties, including antibacterial activity. This study aims to examine the antibacterial effectiveness of moringa leaf extract against the growth of Escherichia coli using the diffusion method. This descriptive-analytical research employed a purposive sampling technique with varying concentrations of moringa leaf extract: 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, and 100%. Each concentration was tested in triplicate, resulting in a total of 30 samples. The antibacterial effectiveness test was conducted using the agar diffusion method with blank paper disks. The results showed that no inhibition zones were formed at concentrations of 10% and 20%. Inhibition zones began to appear at 30% concentration (7.3 mm), increasing with higher concentrations: 40% (9 mm), 50% (10.3 mm), 60% (11.3 mm), 70% (16.6 mm), 80% (23.3 mm), 90% (28.3 mm), and reaching 34.6 mm at 100% concentration. Based on the antibacterial activity category, 10% and 20% showed no activity, 30% and 40% were categorized as weak, 50% and 60% as moderate, 70% as strong, and 80%, 90%, and 100% as very strong. It can be concluded that an 80% concentration of moringa leaf extract is the most effective in inhibiting the growth of Escherichia coli.
The Effect of Different Soaking Times of Gambir (Uncaria gambir (Hunter) Roxb.) on the Examination of Ascaris lumbricoides Eggs as an Alternative Stain to Eosin Tantri Rahmatika; Ari Nuswantoro; Laila Kamilla
MEDICA (International Medical Scientific Journal) Vol. 7 No. 2 (2025): MEDICA (International Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v7i2.512

Abstract

Ascaris lumbricoides is a type of helminth that can infect humans. One laboratory method for its examination is the use of 2% eosin staining with the direct slide method. However, eosin poses potential hazards to both the environment and human health, thus prompting the need for an alternative, eco-friendly staining agent. Gambir (Uncaria gambir (Hunter) Roxb.) contains red catechu, which imparts a red coloration to solutions. This study aims to evaluate the staining differences based on varying soaking times of Gambir extract for staining Ascaris lumbricoides eggs as a natural alternative to eosin. This research is a quasi-experimental study using purposive sampling. The Gambir samples were soaked in 96% ethanol for 1 hour, 1 hour 30 minutes, and 2 hours. Each treatment was replicated 9 times, resulting in a total of 27 samples. The staining was conducted using the direct slide method to examine Ascaris lumbricoides eggs. The results showed that Gambir soaked for 1 hour yielded a staining quality of 41.67%, 1 hour 30 minutes resulted in 68.51%, and 2 hours resulted in 87.96%, while the 2% eosin control achieved a staining quality of 100%. Based on the results of this study on the variation in soaking time of gambier (Uncaria gambir (Hunter) Roxb.) as an alternative dye to eosin in the examination of Ascaris lumbricoides eggs, it can be concluded that the staining success rate increases with longer soaking durations.
Number of Bacterial Colonies After Washing Hands with Antiseptic Soap and Regular Soap: A Study on Department of Health Analyst Students in Poltekkes Kemenkes Pontianak Ari Nuswantoro; Maulidiyah Salim; Slamet; Dinasti Aprillia
Jurnal teknologi Kesehatan Borneo Vol 1 No 2 (2020): Jurnal Teknologi Kesehatan Borneo
Publisher : POLTEKKES KEMENKES PONTIANAK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jtkb.v1i2.27

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Hand washing is a healthy activity carried out by many parties. Getting used to wash your hands properly will increase health. The soap on the market is plain hand washing soap and antiseptic handwashing soap. The second type is claimed to be more effective in reducing the amount of bacterial contamination than plain soap because it contains antimicrobial ingredients to increase product sales. This study aims to determine the differences in the number of bacterial colonies on the palms of students who wash their hands with antiseptic soap and plain soap among students of Analyst Department of Pontianak Health Polytechnic, Minister of Health. This research was quasi-experimental, with 24 respondents. Each respondent was asked to wash hands properly twice, the first with plain soap that does not contain an antiseptic (A) and the second with soap containing antiseptic (B). After examining the number of bacteria on the respondent’s thumb, the average number of bacterial colonies got in treatments A and B was 45,5 and 38,8 CFU, respectively. Mann-Whitney U statistical test results got a probability value of 0.391&gt; 0.05, which means there is no difference in the number of bacterial colonies in the palms that washing hands with plain soap and with antiseptic soap. This study revealed the fact that the number of bacterial colonies in the group that washed hands with antiseptic soap was lower than those who washed their hands with ordinary soap.
Potential of Methanol Extract of Bungli Fruit Seed (Oroxylum Indicum) in Inhibiting the Growth of Escherichia coli Ari Nuswantoro; Natasya Intan Ramadhani
Jurnal teknologi Kesehatan Borneo Vol 2 No 1 (2021): Jurnal Teknologi Kesehatan Borneo
Publisher : POLTEKKES KEMENKES PONTIANAK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jtkb.v2i1.29

Abstract

Bungli (Oroxylum indicum) has been used for generations in Asia as traditional medicine. The seeds of the bungli are commonly used as traditional medicine to treat typhoid, cough, hypertension, internal fever, fever and diarrhea. The active compounds in this plant are known to have anti-inflammatory, antirheumatic, antifungal and antibacterial activities. Our research on methanol extract of bungli fruit seeds showed its potential to inhibit the growth of Escherichia coli bacteria that causes diarrhea. Bungli seed extract samples with a concentration of 25% showed an inhibition zone with a diameter of 9.22 mm, while at a concentration of 50% the diameter was 11.16 mm and 75% had a diameter of 12.88 mm. This size is indeed smaller than chloramphenicol (26 mm), but this potential can be greater if the extraction is carried out more intensively to extract the active compound, the sample concentration is increased, and the part or age of the plant with the highest content of the active compound is used; so that the Bungli plant is expected to be an alternative in overcoming Escherichia coli infection.
Combination of Aloe Vera and Chocolate to Reduce The Number of The Colony of Staphylococcus Aureus Edy Suwandi; Ari Nuswantoro; Sugito Sugito
Jurnal teknologi Kesehatan Borneo Vol 3 No 2 (2022): Jurnal teknologi Kesehatan Borneo
Publisher : POLTEKKES KEMENKES PONTIANAK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jtkb.v3i2.197

Abstract

Aloe vera (AV) and chocolate are good examples of functional foods because they contain prebiotics that can help the host defend itself against harmful bacterial infections such as Staphylococcus aureus. Many studies have used AV or chocolate alone to help fight infection, but not much is known about using both together. This study aims to count the number of colonies of S. aureus infected on mice’s skin (Mus musculus) after being given AV and cocoa in certain doses per kilogram of body weight. A total of 35 healthy male mice were infected with S. aureus in the superficial area of ​​the nape of the skin. After that, they were divided into seven groups, each consisting of 5 mice, and given the following treatments: given 50 mg/kg BW AV (group A), 50 mg/kg BW brown (B), 50 mg/kg BW combination of AV and chocolate (C), given 75 mg/kg BW AV (D), given 75 mg/kg BW brown (E), given 75 mg/kg BW combination of AV and chocolate (F), and control (without prebiotic administration), K). Mice that were given 75 mg/kg BW AV/chocolate/AV+chocolate had a better ability to reduce the number of bacteria than those that were given 50 mg/kg BW AV/chocolate/AV+chocolate. In addition, rats that were given AV and chocolate together had a better ability to reduce the number of bacteria than those that were given either only AV or chocolate alone. Prebiotics are both found in AV and chocolate but with different substances. This causes mice given a combination of prebiotics to be considered better than those given only one type of prebiotic source.
Lipid Profile of Prolanis Patients in Pontianak City Ari Nuswantoro; Dinasti Aprillia; Juliana Cristyaningsih
Jurnal teknologi Kesehatan Borneo Vol 4 No 1 (2023): Jurnal teknologi Kesehatan Borneo
Publisher : POLTEKKES KEMENKES PONTIANAK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jtkb.v4i1.209

Abstract

Perubahan lingkungan, teknologi dan gaya hidup memicu naiknya kasus penyakit tidak menular, seperti diabetes melitus (DM) dan hipertensi (HT), yang bersifat kronis dan membawa risiko kematian terutama di negara berkembang seperti Indonesia. Dua penyakit tersebut dapat dideteksi dengan menilai profil lipid individu dimana kondisi dislipidemia dapat dianggap mengarah pada risiko terjadinya penyakit kardiovaskuler. Pemerintah Indonesia meluncurkan program Prolanis terhadap pasien DM dan HT yang salah satu kegiatannya adalah pemeriksaan profil lipid yang meliputi kadar kolesterol, trigliserida, HDL-kolesterol, dan LDL-kolesterol. Dari hasil pemeriksaan ini dapat dinilai rasio trigliserida terhadap HDL-kolesterol, yang merupakan prediktor paling kuat terhadap penyakit kardiovaskuler. Penelitian ini mengambil data pemeriksaan profil lipid dari 337 pasien Prolanis di Kota Pontianak. Hasil penelitian menunjukkan bahwa pasien DM didominasi oleh orang dengan hiperkolesterolemia (63,03%), trigliserida normal (56,36%), HDL-kolesterol normal (91,51%), LDL-kolesterol tinggi (83,03%), dan rasio trigliserida/HDL-kolesterol normal (60%). Demikian pula pada pasien HT, hiperkolesterolemia dan LDL-kolesterol tinggi dialami sebagian besar pasien (69,76 dan 84,30%), sedangkan trigliserida normal, HDL-kolesterol normal, dan rasio Trigliserida/HDL-kolesterol normal lebih mendominasi dengan persentase 61,61%, 94,19%, dan 68,03%. Hasil penelitian ini menunjukkan bahwa baik pasien DM maupun HT memiliki kecenderungan profil lipid yang normal dan menuju dislipidemia.
Co-Authors Adawiyah, Rabi’atul Aditia Aditia Aditia, Aditia Affifatuzahara Affifatuzahara Affifatuzahara, Affifatuzahara Agus Dimas Ratulangi Al-qorifah, Fahma Ajeng Alfianita, Riska Anisya Nur Shafitri Anjelica, Benedikta Aprilia, Dinasti Ardhani, Adha Riesta Arifah, Rizki Zanuba Artanti, Lina Yunda Aufani, Destia Aulia, Annisa Syafa Azura, Azura Azzahra, Larasabella Bagus Muhammad Ihsan Benedikta Anjelica Desi Wahyumarniasari Devi Nurfitri Bintang Diana Novita Dinasti Aprillia Djohan, Herlinda Edi Santoso Emilda Sari Etiek Nurhayati Fadilla, Alda Nur Fahma Ajeng Al-qorifah Fahrani, Chantika Lailatussa'adah Fitra Fathuhudin Fitri Mega Astuti Fitri Ulya Hartati Grovindo Grovindo Hendra Budi Sungkawa, Hendra Budi Herlinda Djohan Ihsan, Bagus Muhammad Imma Fatayati Indah Purwaningsih Indah Purwaningsih Indrawati, Ratih Jessica Ningtyas Berlianti Jordan, Aristo Juliana Cristyaningsih Kartini Kartini Laila Kamilla Laila Kamilla Linda Triana Linda Triana Liza Harum Nur Annisa Maretalinia Maretalinia Maretalinia, Maretalinia Maulidiyah Salim Merda Sri Rahayu Monalita, Ria Muhammad Ihsan, Bagus Munardi, Fhatia Natasya Natasya Intan Ramadhani Natasya Intan Ramadhani Nur Reza Nurhayati, Etiek Nurul Uq'ma P Purwanto Panyada Cholsakhon Perdede, Lusi Hernawati Pratiwi, Tarisya Fitri Rahayu, Merda Sri Ramadan, Aditiya Ratnawaty, Gervacia Jenny Reza Setiawan Reza, Nur Rezky, Muhammad Andyka Riska Alfianita Rizki Zanuba Arifah Rizki, Sri Yuniarti Romadi Romadi Sadid, Randy Samwidya, Veronika Sriayu Sen, Sharen Shafitri, Anisya Nur Slamet Slamet Sri Tumpuk Sugito Sugito Sugito Sugito Sutriswanto Sutriswanto Suwandi, Edy Syahdilla, Ade Syopingi Syopingi Syopingi, Syopingi Tantri Rahmatika Theresia Indah Budhy Sulisetyawati Tika, Dian Tumpuk, Sri Uq'ma, Nurul Veny Veny Wahdaniah Wahyudi Wicaksono, Didik Yunus, Mohd