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All Journal Jurnal Kedokteran Brawijaya AL KAUNIYAH El-Hayah : Jurnal Biologi Biology, Medicine, & Natural Product Chemistry Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Universa Medicina Jurnal Biologi Tropis Pharmasipha Journal of Dedicators Community Biota Jurnal Kesehatan Islam : Islamic Health Journal INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Jurnal Pemberdayaan Masyarakat Universitas Al Azhar Indonesia Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Jurnal Riset Biologi dan Aplikasinya JSMARTech : Journal of Smart Bioprospecting and Technology BioEksakta : Jurnal Ilmiah Biologi Unsoed J-PEN Borneo : Jurnal Ilmu Pertanian Jurnal Sains Alami (Known Nature) Berkala Penelitian Hayati Agrikan: Jurnal Agribisnis Perikanan Jurnal Kedokteran Hewan Jurnal Sains Alami (Known Nature) ICONESTH KOPEMAS Jurnal Ragam Pengabdian Jurnal Agroindustri Halal
Nour Athiroh Abdoes Sjakoer
Universitas Islam Malang
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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METODE PEMBELAJARAN KONSEP BIOLOGI MOLEKULER MELALUI PENDEKATAN IN SILICO DI SMA DIPONEGORO, NEGARA, BALI Gatra Ervi Jayanti; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarakati
Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024 Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) 2020
Publisher : Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024

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Abstract

Kemajuan teknologi yang pesat akan membawa pengaruh terhadap kehidupan. Penggunaan teknologi yang tepat akan memudahkan aktivitas manusia, contohnya dalam bidang pendidikan. Pendidikan dapat diakses dengan mudah melalui komputer, laptop dan ponsel pintar. Berbagai bidang ilmu memanfaatkan kecanggihan teknologi, salah satu contohnya adalah Biologi. Ilmu Biologi menggunakan perangkat lunak untuk permodelan, dan prediksi, yang biasa disebut in silico. Tujuan dari kegiatan pengabdian masyarakat ini adalah untuk mengenalkan ilmu Biomolekuler secara sederhana dan aplikasinya melalui pendekatan in silico pada siswa SMA. Metode pelaksanaan kegiatan ini dengan menjelaskan materi tentang in silico dan penerapannya dalam kehidupan, serta diadakan tanya jawab. Hasil dari pengabdian ini terlihat dari tanggapan positif dan antusias siswa.  
DISEMINASI RAMUAN KOMBINASI BENALU TEH DAN BENALU MANGGA SEBAGAI ANTIHIPERTENSI DI GRIYA JAMU KOTA BATU Nour Athiroh Abdoes Sjakoer; Erna Sulistyowati; Yudi Purnomo; Majida Ramadhan; Anita Puspa Widiyana; Husain Latucosina
Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024 Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) 2022
Publisher : Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024

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Abstract

Ramuan kombinasi benalu teh-benalu mangga merupakan produk yang dapat mengurangi resiko hipertensi. Diseminasi kombinasi benalu teh-benalu mangga yang diikuti oleh peserta bertujuan menyelesaikan permasalahan mitra meliputi pemahaman terhadap hipertensi, pemeriksaaan terhadap tekanan darah, asam urat, dan kolestrol, serta penilaian diseminasi ramuan kombinasi benalu teh-benalu mangga. Metode yang dilakukan meliputi diseminasi dan sosialisasi program PkM, pelatihan dan praktik langsung pembuatan ramuan kombinasi benalu teh-benalu mangga, pembentukan kelompok, melaksanakan FGD, seminar hasil PkM, monitoring dan evaluasi internal dan eksternal, evaluasi PkM, laporan program PkM, Publikasi, pendampingan dan rencana tindak lanjut. Penilaian beberapa aspek dianalisis melalui uji t berpasangan. Hasil penilaian tingkat pemahaman responden terhadap hipertensi menunjukkan bahwa terjadi peningkatan pengetahuan yang signifikan setelah dilakukan sosialisasi khususnya tentang ciri-ciri penderita, pola makan sehat penderita hipertensi, dan pencegahan hipertensi. Pemeriksaaan tekanan darah, asam urat dan kolestrol menunjukkan hasil yang cenderung tinggi. penilaian pengetahuan terhadap ramuan kombinasi benalu teh-benalu mangga juga meningkat secara signifikan. Beberapa faktor penting menjadi pendukung peningkatan pengetahuan tentang hipertensi dan herbal benalu teh-benalu mangga, serta hasil pemeriksaan kesehatan.
Exploration and Identification of Endophytic Molds on Leaves and Stem of the Mango’s Mistletoe (Dendrophthoe Pentandra (L.) Miq) Ayu Pertiwi, Chintya; Abdoes Sjakoer, Nour Athiroh; Jadid Mubarakati, Nurul; Fatimah, Fatimah
Jurnal Riset Biologi dan Aplikasinya Vol. 5 No. 2 (2023)
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jrba.v5n2.p79-88

Abstract

Mango’s mistletoe is one of the herbal plants’ rich in bioactivity. Secondary metabolites are not only produced by plants but also by microorganisms that live in tissues. One of these microorganisms is endophytic mold. The ability of endophytic molds to synthesize secondary metabolites is an opportunity for large-scale production in a short time without causing the exploitation of natural materials. This research aimed to explore and identify endophytic molds from the leaves and stem of the mango mistletoe to obtain the genus of molds. The stages of this research consisted of isolation by direct planting with sterilization, purification, growth rate measurement, characterization, and identification carried out macroscopically and microscopically. DBM 1 and DBM 2 belong to Aspergillus sp., DBM 3 belongs to Cladosporium sp., DBM 4 belongs to Neurospora sp., TDBM 1, TDBM 2, and TDBM 3 belong to Hormiscium sp. The growth rate of Aspergillus sp. relatively fast, with the increase in diameter of Aspergillus sp.1 colony from 2.45 cm to 5.05 cm and that of Aspergillus sp.2 from 2.73 cm to 5.35 cm. In the Cladosporium sp., there was an exponential phase with an increase in diameter from 2.15 cm to 4.65 cm. In Neurospora sp., there was an exponential phase with an increase in diameter from 0.63 cm to 3.65 cm. The growth rate of Hormiscium sp. is quite fast, with an exponential phase with an increase in the diameter of the colonies of Hormiscium sp.1 from 2.63 cm to 7.21 cm, Hormiscium sp.2 from 2.45 cm to 6.94 cm and Hormiscium sp.3 from 2.85 cm to 7.85 cm.
A COMPARISON OF ANTIOXIDANT ACTIVITY IN TEA MISTLETOE (Scurrula atropurpurea (Bl.) Dans.) LEAF EXTRACTS USING DPPH ASSAY Forrela Zahwa Salamah; Nour Athiroh Abdoes Sjakoer; Majida Ramadhan
International Conference on Education, Science, Technology and Health (ICONESTH) 2024: The 2nd ICONESTH
Publisher : International Conference on Education, Science, Technology and Health (ICONESTH)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46244/iconesth.vi.430

Abstract

The general public often regards mistletoe as a parasitic plant that can harm other plants. However, some communities aware of its benefits have utilized mistletoe as an alternative treatment for various diseases. Tea mistletoe (Scurrula atropurpurea (Bl.) Dans.) is one type of mistletoe that the community has used to treat various ailments. Based on phytochemical analysis, this plant contains active compounds such as flavonoids, alkaloids, steroids, tannins, saponins, phenolics, and glycosides, which act as antioxidants. Therefore, this study was conducted to provide new information about the potential of tea mistletoe (Scurrula atropurpurea (Bl.) Dans.) leaf extract as a natural antioxidant with low toxicity effects through the DPPH method and to demonstrate the effectiveness of this natural antioxidant in inhibiting free radicals. This research is an experimental laboratory study with a quantitative approach. A series of sample concentrations was prepared, with 0,15 mL of each concentration placed into a 12-well plate and homogenized with 2,85 mL of 0,1 mM DPPH solution. The mixture was incubated for 30 minutes before its absorbance was measured using a UV-Visible Spectrophotometer. The results of this study showed that tea mistletoe (Scurrula atropurpurea (Bl.) Dans.) leaf extract exhibited very strong antioxidant activity, with an IC50 value of 3,32 ppm, comparable to quercetin. Keywords: tea mistletoe, DPPH, antioxidant, extract.
Pengaruh pemberian benalu teh dan benalu mangga terhadap kadar malondialdehid serum pada tikus wistar jantan Ma'ruf, Muhammad; Sjakoer, Nour Athiroh Abdoes; Mubarakati, Nurul Jadid; Kumalasari, Eka
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 9 No. 1 (2025): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v9i1.12534

Abstract

Tea mistletoe and mango mistletoe are plants known to possess strong antioxidant activity. The antioxidants in these plants play a role in combating free radicals, inhibiting cell oxidation, and reducing the risk of cellular damage. The active compounds present in tea and mango mistletoe have the potential to reduce malondialdehyde (MDA) levels caused by free radical exposure. This study aimed to evaluate the effect of tea and mango mistletoe (BTBM) administration on MDA levels in male Wistar rats induced with deoxycorticosterone acetate (DOCA)-salt. This study used 25 male Wistar rats, divided into five groups: normal, control (DOCA-salt), and three treatment groups receiving BTBM at doses of 50, 100, and 200 mg/kgBW. The study lasted 28 days, beginning with BTBM administration for 14 days, followed by DOCA-salt induction alongside BTBM administration from day 15 to day 28. MDA levels were measured using the Thiobarbituric Acid Reactive Substances (TBARS) method with a UV-Vis spectrophotometer at a wavelength of 531 nm. Data were statistically analyzed using one-way ANOVA, followed by a Post Hoc Tukey test to determine differences between groups. The results showed that BTBM administration at a dose of 50 mg/kgBW significantly (p<0.05) reduced MDA levels compared to the control group. Thus, it can be concluded that the combination of tea and mango mistletoe has potential as an antioxidant agent in reducing MDA levels, with 50 mg/kgBW as the optimal dose in the DOCA-salt-induced rat model.      
Potensi Antikapang Ekstrak Etanol Daun Benalu teh (Scurrula atropurpurea (Bl.) Dans) terhadap Candida albicans Secara in Vitro Husain, Muhammad Hafizh; Sjakoer, Nour Athiroh Abdoes; Faisal, Faisal
BioEksakta : Jurnal Ilmiah Biologi Unsoed Vol 7 No 2 (2025): BioEksakta
Publisher : Fakultas Biologi Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.bioe.2025.7.2.15801

Abstract

Benalu teh (Scurrula atropurpurea (Bl.) Dans) merupakan tanaman yang mengandung senyawa bioaktif seperti flavonoid, alkaloid, tanin, fenolik, dan terpenoid yang berpotensi sebagai antifungi alami. Candida albicans adalah jamur oportunistik yang secara alami terdapat dalam tubuh manusia, namun dapat menyebabkan infeksi apabila terjadi ketidakseimbangan sistem imun atau perubahan lingkungan mikroba. Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak etanol daun benalu teh dalam menghambat pertumbuhan Candida albicans secara in vitro. Metode yang digunakan adalah eksperimen dengan desain Rancangan Acak Lengkap (RAL) menggunakan teknik pengenceran bertingkat (serial dilution) dan metode sebar (spread plate) pada media Potato Dextrose Broth (PDB) dan Potato Dextrose Agar (PDA). Hasil penelitian menunjukkan bahwa ekstrak mulai efektif terhadap Candida albicans pada konsentrasi ≥12,5%, dengan Kadar Hambat Minimum (KHM) optimal pada 6,25% (OD 1,310 nm). Uji ANOVA menunjukkan adanya perbedaan yang signifikan terhadap pertumbuhan Candida albicans (p<0,05). Ekstrak etanol daun benalu teh memiliki potensi sebagai antifungi terhadap Candida albicans. Kata kunci : Antikapang, Benalu teh, Candida albicans.
Potential Combination of Cermai (Phyllanthus acidus) and Mulberry (Morus alba) Fruit Extract as a Candidate For Tyrosinase Inhibitor Susanti, Erna; AS, Nour Athiroh; Ramadhan, Majida; Mardhiyah, Mardhiyah; Noor, Mahanem Mat
Al-Kauniyah: Jurnal Biologi Vol 18, No 2 (2025): AL-KAUNIYAH JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v18i2.42571

Abstract

Melanin, a pigment derived from UV radiation, is crucial in preventing skin damage and can cause aesthetic and dermatological problems such as hyperpigmentation or hypopigmentation. Melanogenesis is a complex process involving enzymes and cytokines, with UV being a primary contributor. Tyrosinase is a key enzyme in melanin synthesis. This study aims to test the potential of combining cermai fruit extract (CE) and mulberry fruit (ME) as a tyrosinase inhibitor. The tests included antioxidant activity using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method, total phenolic content using the Folin Ciocalteu method, flavonoid content using the AlCl3 colorimetric method, and sun protection factor (SPF) value using UV-Vis spectrophotometric method. The results showed that the highest total phenolic content was observed in (CE), followed by the combination of ME: CE in the ratio of 1:3, 1:1, 3:1, and then ME. The same pattern was seen in the flavonoid content assay results. The antioxidant activity, as indicated by the IC50 values, followed the following order CE 418.30%; ME: CE (1:3) 400.49%; ME: CE (1:1) 367.73%; ME: CE (3:1) 358.04%; and ME 344.43%. The highest SPF value was observed in ME. It can be concluded that this study shows that the combination of CE and ME extracts has potential as a tyrosinase inhibitor and skin protective agent from hyperpigmentation due to UV exposure.
Edukasi jamu dan ramuan herbal dan untuk mencegah COVID-19 pada kader penggerak PKK Kota Batu Sulistyowati, Erna; Purnomo, Yudi; Latuconsina, Husain; Ramadhan, Majida; Widiyana, Anita Puspa; Hidayatullah, Muhammad Fahmi; AS, Nour Athiroh
Journal of Dedicators Community Vol 6, No 3 (2022)
Publisher : Universitas Islam Nahdlatul Ulama Jepara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34001/jdc.v6i3.2853

Abstract

Pandemi Coronavirus disease atau yang biasa disebut COVID-19 menimbulkan dampak di berbagai sektor kehidupan masyarakat. Perlu upaya serius untuk meningkatkan ketahanan tubuh dengan memanfaatkan ramuan herbal yang banyak kita jumpai di kebun tanaman obat keluarga. Program edukasi kader penggerak PKK tentang ramuan herbal pencegahan COVID-19 ini dilaksanakan di Kota Batu propinsi Jawa Timur. Penyampaian program melalui ceramah, pelatihan dan FGD UMKM Griya Jamu Siti Ara Kota Batu pada Desember 2021. Edukasi interaktif dengan memberikan materi berupa ceramah tentang khasiat jamu/herbal dan pelatihan keterampilan meracik jamu/herbal.  Analisis uji korelasi Kendall’s tau-b menunjukkan adanya hubungan karakteristik sosioekonomi dan pendidikan dengan persepsi COVID-19. Uji korelasi Pearson menunjukkan tidak terdapat hubungan paparan COVID-19 dengan persepsi peserta engan COVID-19. Danlagi, uji Chi-Square menunjukkan tidak terdapat hubungan karakteristik sosioekonomi dan pendidikan peserta dengan perilaku konsumsi jamu atau herbal. Sejumlah 35 peserta terlibat aktif selama kegiatan. Domisili mereka meliputi seluruh wilayah Kota Batu, Malang Jawa Timur. Dapat disimpulkan bahwa program edukasi ramuan herbal pada penggerak kader PKK mampu meningkatkan pengetahuan dan pemahaman masyarakat dalam pemanfaatan jamu/herbal untuk mencegah COVID-19 kepada seluruh lapisan masyarakat.
Phytochemical Screening and Determination of Total Flavonoid Content of Keji Beling Leaves Ethanol Extract (Strobilanthes crispa Bl.) Mahyantika, Seftya Putri; Husain, Muhammad Hafizh; Nirwana, Linggar; Aldina, Devana Rahma; Gemilang, Satria; Nafisa, Nafisa; Ramadhan, Majida; Sjakoer, Nour Athiroh Abdoes; Faisal, Faisal
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.219-224

Abstract

This study aims to determine the total flavonoid content in the ethanol extract of keji beling (Strobilanthes crispa) leaves using the UV-Vis spectrophotometric method with AlCl3 reagent. The research process includes maximum wavelength testing, preparation of quercetin standard solution, and analysis of total flavonoid levels. The results showed that the total flavonoid content in the extract was 144.347 ± 134.854 mg QE/g extract, with an extract yield of 0.4% and extract moisture content of 5.256%, which showed good potential in preventing the growth of microorganisms. Phytochemical screening revealed the presence of alkaloids, flavonoids, and tannins, while saponins, triterpenoids, and steroids were not detected. These findings confirm the importance of secondary metabolite compounds in plants and the potential of keji beling leaf extract as a source of active compounds with health benefits, including antioxidant and antibacterial activities. This study provides a basis for further research into the medical applications of this plant extract.
Identification of Secondary Metabolite compounds and Testing of Flavonoid Levels in Beluntas Leaves (Pluchea indica L.) Salamah, Forrela Zahwa; Ramadhani, Mieta Widya; Wahidah, Shinta Nuriyah; Rahmawati, Rizka Dwi; Sjakoer, Nour Athiroh Abdoes; Savana, Amartya Gesit; Ramadhan, Majida; Faisal, Faisal; Nafisa, Nafisa
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8473

Abstract

Most Indonesian people still use traditional medicine because Indonesian medicinal plants can potentially be the main ingredient in medicine They contain various types of natural chemical compounds with diverse pharmacological and biodiversity effects. Several plants that usually grow around the yard and are easy to grow are beluntas (Pluchea indica (L.)). Beluntas are consumed as an additional ingredient when eating or processed as a herbal concoction. This study identified secondary metabolite compounds and total flavonoid levels in beluntas leaves. Beluntas leaves (Pluchea indica (L.)) were extracted using ethanol solvents and then tested using several reagents to identify their compound content. The total flavonoid test in the beluntas leaf extract was also conducted by adding a 10% aluminum chloride solution, sodium acetate, and aquadest to the extract sample, then incubated and measured for absorption using UV-Vis spectrophotometry in the wavelength range between 415-440 nm. This study demonstrates that beluntas leaves contain bioactive compounds including steroids, alkaloids, flavonoids, and tannins with a total flavonoid content recorded at 71.567±70.446 mg/g.
Co-Authors Abdur Rohman Wahid Ahmad Baidarus Ahmad Taufiq Aisyah Aisyah Aldina, Devana Rahma Andini, Saskia Ade Hutami Fery Anita Puspa Widiyana Anna Fathiah Annisatul Hakimah Ar Rahmah, Mumtazunnisa As Sufiyah Argus Argus Argus Mahyan Ari Hayati Ari Hayati Arina Roikhana Ariski Vevi Liswandari Ayu Pertiwi, Chintya Baidarus, Ahmad Dea Fatimatu Zahroh Devi Qurroti A'yun Dewi Qurrot &#039;Aini Dewi Qurrot 'Aini Doti Wahyuningsih Dwi Kartika Wati Dwi Mareta Nur hidayati Dyan Aprillia Susanti Eka Kumalasari Eko Noerhayati Erna Sulistyowati Erna Susanti fahmiy, Rakhmawati Faisal Faisal Faisal Faisal Fajrin, Siti Awaliah Fatimah Abdul Sammad fatimah Fatimah Fatimah Fatimah Fatur rohman Rohman Forrela Zahwa Salamah Gatra Ervi Jayanti Gemilang, Satria Hari Santoso hari santoso Hari Santoso Hari Santoso Hari Santoso Hari Santoso Hasan Zayadi Hasanah, Durrotul Hatif Khusnin Nida' Herlinda Rahayu Husain Latuconsina Husain Latucosina Husain, Muhammad Hafizh Istirochah Pujiwati Jadid Mubarakati, Nurul Jihan Farah Zakia Kammal Nizam Amrullah Laili Mihmidati Lestari, Tengku Anggun Luluk Rofiatul Mafluhah M. Abdul Qodir Jailani M. Mas’ud Said Ma'ruf, Muhammad Mahanem Mat Noor, Mahanem Mat Mahyantika, Seftya Putri Maidhatul Rosidha Widyanti Majida Ramadhan Malia Anjani Mardhiyah, Mardhiyah Masyhuri Masyhuri Mihmidati, Laili Mohammad Mabrur Mubarokati, Nurul Jadid Muhammad Fahmi Hidayatullah Nafisa Nafisa Nafisa, Nafisa Nia Novita Nurrohmah Nirwana, Linggar Nur hidayati, Dwi Mareta Nur Mufida Nur Permatasari Nur Shofiyah Munawaroh Nur Shofiyah Munawaroh, Nur Shofiyah Nurrohmah, Nia Novita Nurul Jadid Mubarakati Nurul Jadid Mubarakati Nurul Jadid Mubarokati Oktaviana, Nimas Ajeng Rahayu Dwi Lestari Rahmawati, Rizka Dwi Rakhmawati fahmiy Ramadhan, Majida Ramadhani, Mieta Widya Ratna Djuniwati Lisminingsih Ratna Juniwati Lisminingsih Rizki Kusuma Hantika Saimul Laili Salamah, Forrela Zahwa Salsabilatul Mukarommah Saputri, Syntia Diyah Hayu Ria Savana, Amartya Gesit Shinta mayangsari Sholikha alaiya Sholikha alaiya, Sholikha Silfi hamidatul lailiyah Silvia, Putri Azizatul Siti Asmaniyah Mardiayani Siti Awaliah Fajrin Siti Imama Khoiriyah Siti Qurrotul Aini Suroyya, Mariyam Susanti, Dyan Aprillia Tania Putri Nur Yasinta Tengku Anggun Lestari Umu Intan Kinasih Uyunul Hikmah Wahidah, Shinta Nuriyah Yudi Purnomo Zahroh, Dea Fatimatu Zakia, Jihan Farah