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Potensi Pangan Fermentasi Tempe dalam Mengatasi Kejadian Malnutrisi Devina Adira Azzahra; Desi Rahmasari; Hanayu Anindya Nareswari; Margaretha Alesandria Natasya Weka; Rizka Fellithia; Liss Dyah Dewi Arini
Student Scientific Creativity Journal Vol. 3 No. 2 (2025): Student Scientific Creativity Journal
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/sscj-amik.v3i2.5511

Abstract

Malnutrition remains a significant public health challenge, particularly in developing countries like Indonesia. Tempeh, a fermented soybean product, is highly nutritious and has the potential to address malnutrition. The fermentation process by Rhizopus oligosporus enhances the bioavailability of essential nutrients such as protein, iron, and vitamin B12, which are crucial for growth and development. Additionally, tempeh contains natural prebiotics and probiotics that support digestive health and improve nutrient absorption. A literature review in this study indicates that regular consumption of tempeh can help improve nutritional status, particularly among vulnerable groups such as children and pregnant women. With its affordability and wide availability, tempeh serves as a sustainable food solution that can be optimized to reduce malnutrition rates in Indonesia.
Studi Toksikologi Biokimia : Dampak Senyawa Beracun Terhadap Proses Metabolisme Seluler dan Kesehatan Manusia David Valentino Iskandar; Karina Sella Juwitasari; Erlanda Islami Pasha; Elsa Trisna Sari; Liss Dyah Dewi Arini
Student Scientific Creativity Journal Vol. 3 No. 2 (2025): Student Scientific Creativity Journal
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/sscj-amik.v3i2.5520

Abstract

Biochemical toxicology studies are disciplines that study the impact of toxic compounds on biochemical processes in the human body. Toxic compounds, whether from the environment, industrial chemicals, drugs, or natural products, can interfere with cellular metabolic mechanisms and potentially cause damage to organs or body systems. This study aims to analyze how toxic compounds interact with biomolecules, such as proteins, enzymes, and nucleic acids, which play a role in cellular metabolic processes. Disruption of metabolic enzymes can affect key metabolic pathways, such as energy synthesis, detoxification, and homeostasis regulation. These toxic impacts can contribute to the development of acute and chronic diseases, including liver, kidney, nervous system disorders, and cancer. In this study, we also discuss the detoxification mechanisms involving enzymes such as cytochrome P450 and glutathione-S-transferase in reducing the toxic effects of these compounds. A deeper understanding of toxic interactions and their impact on cellular metabolism is essential in developing preventive and therapeutic strategies for poisoning or toxicity-related diseases. This research is expected to provide insight into the development of more effective drugs and medical approaches in overcoming the effects of toxic toxins on humans.
Management of Cancer in the Digestive System Liss Dyah Dewi Arini; Warsi Maryati; Puguh Ika Listyorini; Devi Pramita Sari
International Journal of Health and Medicine Vol. 1 No. 3 (2024): July : International Journal of Health and Medicine
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhm.v1i3.33

Abstract

Cancer is a non-communicable disease characterized by the presence of abnormal cells/tissues that are malignant, grow quickly and uncontrollably and can spread to other places in the patient's body. Cancer cells are malignant and can invade and damage the function of the tissue. Digestive cancer, also called gastrointestinal cancer, attacks the organs of the digestive system. Digestive cancer also includes gastrointestinal cancer, liver cancer, stomach cancer, colorectal cancer, and pancreatic cancer. Risk factors for digestive cancers are varied because many different organs can be affected. Some factors that contribute to cancer throughout the digestive system include age, heavy drinking (alcohol), smoking, and diabetes sufferers. This type of liver cancer is cancer that grows in liver cells. Liver cancer is a type of cancer that ranks second as the cancer that causes the most deaths in the world. Gastric cancer is a group of malignant diseases that have multifactorial causes, namely genetic, lifestyle and environmental factors. The symptoms caused by stomach cancer are initially not as typical as the symptoms of general digestive complaints. The diagnosis of colorectal cancer can be carried out in stages, including through an appropriate history, physical examination, and supporting examinations in the form of laboratory examinations, both from clinical laboratories and anatomical pathology laboratories. The etiology of colorectal cancer is currently still unknown. Symptoms of colorectal cancer are varied and non-specific. The main complaints of patients with colorectal cancer relate to the size and location of the tumor. Tumors in the right colon, where the contents of the colon are fluid, tend to remain hidden until they are very advanced.
Optimalisasi Pertumbuhan Bakteri Propionibacterium Acnes pada Media Nutrien Agar Nadia Budi Agustina; Nadya Bening Putri Febriyani; Piana Astuti; Tessalonika Ersaputri; Liss Dyah Dewi Arini
Intellektika : Jurnal Ilmiah Mahasiswa Vol. 3 No. 3 (2025): Intellektika : Jurnal Ilmiah Mahasiswa
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/intellektika.v3i3.2661

Abstract

Propionibacterium acnes is an anaerobic bacteria that plays an important role in dermatological research, especially in the context of skin diseases such as acne vulgaris. This study aims to optimize the growth conditions of Propionibacterium acnes in sodium media in order to increase the effectiveness of bacterial culture on a laboratory scale. The parameters tested include media pH, sodium concentration, incubation temperature, and incubation time. The research method was carried out systematically and controlled with a completely randomized design using several environmental condition treatments. The results showed that optimal growth of Propionibacterium acnes was achieved in media with a pH of 6.5–7.0, a sodium concentration of 1.5%, an incubation temperature of 37°C, and an incubation time of 72 hours in conditions without oxygen (anaerobic). By knowing the right conditions, Propionibacterium acnes bacteria can grow faster and optimally, so that it can help in dermatological research or product development related to skin health.
Efektivitas Penggunaan Pewarna Metilen Blue dalam Pengamatan Bentuk Sel pada kulit katak Azzahra Nabilla Atha; Erika Dwi Susanti; Azizah Zahra Nur Fitria; Erlanda Islami Pasha; Elsa Trisna Sari; Nur Aini Fatna Fadilla; David Valentino Iskandar; Liss Dyah Dewi Arini
Nian Tana Sikka : Jurnal ilmiah Mahasiswa Vol. 3 No. 4 (2025): Nian Tana Sikka : Jurnal ilmiah Mahasiswa
Publisher : Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59603/niantanasikka.v3i4.928

Abstract

This study aims to evaluate the effectiveness of using Methylene Blue stain in the microscopic observation of frog skin cell structures. Cell staining is an essential technique in histological studies, as it enhances the visibility of cellular components that are otherwise difficult to observe without contrast. Methylene Blue is known to have a high affinity for acidic components within the cell nucleus, thus providing a clearer depiction of nuclear and cell membrane structures. This research employed a descriptive experimental method by preparing frog skin tissue samples stained with Methylene Blue and observing them under a light microscope. The results indicated that Methylene Blue staining produced high contrast, allowing for the identification of hexagonal-shaped cells and dark, centralized nuclei. The obtained microscopic images revealed a uniform distribution of cells with clearly observable morphological structures. Therefore, Methylene Blue is proven to be effective in enhancing the microscopic visualization of epithelial tissue in frog skin and is recommended for use in both educational and basic biological research contexts.
Peningkatan Pengetahuan Ibu-Ibu Peserta Posyandu di Posyandu Salak, Celengan, Tasikmadu Mengenai Pengaruh Pasteurisasi Terhadap Jumlah Koloni Bakteri pada Susu Segar dan UHT Liss Dyah Dewi Arini; Fredericus Pramonodjati; Saryadi, Saryadi
Jurnal Pengabdian Bidang Kesehatan Vol. 3 No. 2 (2025): Jurnal Pengabdian Bidang Kesehatan
Publisher : PPNI UNIMMAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jpbidkes.v3i2.184

Abstract

Mother is a leader in a family whose duties include managing the family's healthy food and drink needs. One of the nutritious drinks that must be consumed by family members is milk. However, many family members do not understand about pasteurization or heating and non-pasteurization in cow's milk. In milk that has undergone pasteurization, the number of bacteria is less than in milk that has not undergone pasteurization. This community service activity aims to provide an understanding to the mothers of the Posyandu in Celengan, Kaling, Tasikmadu, Karanganyar villages to find out about contamination in pasteurized and non-pasteurized milk, to provide counseling to the mothers of the Posyandu about pasteurized milk and non-pasteurized milk. The counseling method is carried out using the lecture method and explanations about pasteurized and non-pasteurized milk and bacterial contamination in milk with posters and power points. The results of this community service activity are that the mothers of the Posyandu understand the differences between pasteurized and non-pasteurized milk and the presence of more bacterial contamination in non-pasteurized milk. The conclusion of this community service activity is that Posyandu mothers can learn the benefits of pasteurized milk for the body.
Optimalisasi Pertumbuhan Bakteri Propionibacterium Acnes pada Media Nutrien Agar Nadia Budi Agustina; Nadya Bening Putri Febriyani; Piana Astuti; Tessalonika Ersaputri; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 3 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i3.2691

Abstract

Propionibacterium acnes is an anaerobic bacteria that plays an important role in dermatological research, especially in the context of skin diseases such as acne vulgaris. This study aims to optimize the growth conditions of Propionibacterium acnes in sodium media in order to increase the effectiveness of bacterial culture on a laboratory scale. The parameters tested include media pH, sodium concentration, incubation temperature, and incubation time. The research method was carried out systematically and controlled with a completely randomized design using several environmental condition treatments. The results showed that optimal growth of Propionibacterium acnes was achieved in media with a pH of 6.5–7.0, a sodium concentration of 1.5%, an incubation temperature of 37°C, and an incubation time of 72 hours in conditions without oxygen (anaerobic). By knowing the right conditions, Propionibacterium acnes bacteria can grow faster and optimally, so that it can help in dermatological research or product development related to skin health.
Penggunaan Safranin sebagai Pewarna Alternatif dalam Pengamatan Mikroskopik Daun Bayam Amelia Putri Az Zahra; Azlinatul Lulu Kharolaini; Feni Atika Tsuroya; Khotimah Nur Ramadhani; Pramai Sheila eka khoireina; Septi Puspita Kurniawati; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 3 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i3.2925

Abstract

Microscopic staining is an important technique in observing plant tissue to increase contrast and clarify cellular structures. One of the dyes commonly used in plant tissue studies is Safranin, a cationic base compound from the azo group that has a high affinity for cell components that produce negative impacts such as lignin and nucleic acids. This study aims to determine the effectiveness of Safranin as an alternative dye in microscopic observation of spinach leaf tissue (Amaranthus spp.). The practicum was carried out using the wet preparation method, using cross-sections of spinach leaves stained with Safranin solution, then observed under a light microscope. The results showed that Safranin was able to provide good red color contrast to cell walls, cell nuclei, and blood vessel tissue, so that structures such as epidermis, palisade tissue, sponges, and xylem and phloem could be clearly identified. However, obstacles arise in the regulation of concentration and duration of staining, where excess of both can cause excess and excessive structural accuracy. Therefore, adjustment of technical parameters is needed to obtain optimal results. These findings indicate that Safranin is effective as a microscopic dye and has the potential to be used in educational practicum activities, because it is economical, safe, and easy to apply. This study also applies the interdisciplinary application of chemistry and biology in science learning.
Pentingnya Mengetahui Golongan Darah Anda: Dampaknya pada Kesehatan dan Kehidupan Sehari-hari Tyara Avrilyanti Ghea Indriansyah; Karina Sella Juwitasari; Margaretha Alesandria Natasya Weka; Pramesti Listanto; Latifa Alya Khairunnisa; Juwita Ramadhani Octavianingrum; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 3 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i3.2947

Abstract

Knowledge of one’s blood type plays a crucial role in supporting individual health and preparedness in medical emergencies. This literature review explores the relationship between the ABO and Rhesus blood group systems and various health outcomes, including susceptibility to infections, cardiovascular risks, and biochemical implications in personalized medicine. Based on a synthesis of ten scholarly sources, the findings reveal that blood type influences vulnerability to COVID-19, gastrointestinal infections, and elevates cardiovascular disease risk particularly among non-O blood types. These results emphasize the importance of early education and blood type screening as preventive measures. The study also highlights the need for integrating blood type data into national health care systems.
Efektivitas Penggunaan Pewarna Metilen Blue dalam Pengamatan Bentuk Sel pada Kulit Katak Azzahra Nabilla Atha; Erika Dwi Susanti; Azizah Zahra Nur Fitria; Erlanda Islami Pasha; Elsa Trisna Sari; Nur Aini Fatna Fadilla; David Valentino Iskandar; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 3 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i3.3021

Abstract

This study aims to evaluate the effectiveness of using Methylene Blue stain in the microscopic observation of frog skin cell structures. Cell staining is an essential technique in histological studies, as it enhances the visibility of cellular components that are otherwise difficult to observe without contrast. Methylene Blue is known to have a high affinity for acidic components within the cell nucleus, thus providing a clearer depiction of nuclear and cell membrane structures. This research employed a descriptive experimental method by preparing frog skin tissue samples stained with Methylene Blue and observing them under a light microscope. The results indicated that Methylene Blue staining produced high contrast, allowing for the identification of hexagonal-shaped cells and dark, centralized nuclei. The obtained microscopic images revealed a uniform distribution of cells with clearly observable morphological structures. Therefore, Methylene Blue is proven to be effective in enhancing the microscopic visualization of epithelial tissue in frog skin and is recommended for use in both educational and basic biological research contexts.
Co-Authors Aan Riski Susanto Achsanul Ghiffari As Syafi Adelia Bekti Widyaningrum ADITYA KURNIAWAN Afrian Yohans Fernandho Agostinha Morais Assis Belo Akmal Alif Muzakki Aldona Diva Aurelia Alicia Syifa Alifah Gita Cahyani Roqimah Alifia Fara Yuliananda Alma Danita Aloysius Ekawardaya Alya Afriana Syahrani Alya Sagita Alysia Ivanda Candra Ramadhani Amalia Bintang Firshana Ambar Setiti Amelia Putri Az Azahra Amelia Putri Az Zahra Ananda Meyrika Arthama Ananda Olivia Febriyani Anang Kurniawan Anastasya Elisa Cahya Dewi Andhini Saskia Andreas Danang Saputra Angella Putri Ramadhani Anggelli Marsha Pattinama Anggraini Sih Prabandari Ani Nur Fauziah Anik Sulistiyanti Anindita Hidayatul Qolbiyah Anisa Putri Utami Anisya Candra Denvisintami Annatsa Yolantiara Mahanani Annisa Birrul Annisa Nur Agustin Annisa Yuli Kartika Sari Apriani Esma Aqila Widya Ardina Rayshabilah Ariana Agustin Ariangesty Safitri Arifatul Khoirunnisak Arinda Sumarna Ariska Sukma Romadhani Arya Listyo Adi Aryanti Putri Lestari Aryna Agustin Nur Hidayah Assyifa Friska Astrid Tyas Wardhani Aula Nafit Aurel Tata L Avelino Gomes dos Santos AYU WULANDARI Az-zhara Diah Putri Nugroho Azahra Salma Salsabila Putri Azizah Nabhila Azizah Zahra Nur Fitria Azlinatul Lulu Kharolaini Azzahra Nabilla Atha Bagus Muhamad Ridwan Bana Handaga Bangun Prajadi Cipto Utomo Bernadytha Ratriani Putri Celsi Olivia Chika Adelia Saftri Chika Muthi’atul Fadhilah Claudia Aulia Danian Pasha Pratama Darah Ifalahma David Valentino David Valentino Iskandar Della Nur’Aini Denisya Risqi Amelia Desi Rahmasari Desianti Cahya Nugraheni Devi Pramita Sari Devi Pramita Sari Devina Adira Azzahra Devina Saraswati Dhionisius David Mario Dhita Widya Ananta Dhuwi Noviyanti Dian Elizar Dinda Cinthya Nur Novalinda Dinda Daniela Sri Putri Diva Precillia Sari Dwi Ratih Rahayu Dwi Setia Ningsih Dwinanda Novitasari Echa Ananta Perdani Eka Yolanda Putri Ellen Nur Fauziah Elsa Oktavia Ramadhani Elsa Trisna Sari Eni Retnaningsih Enjeli Kurnia Safitri Erika Dwi Susanti Erlanda Islami Pasha Erma Nurhayati Firdaus Etik Yuniarsih Evanda Gita Septiana Evans Tiandra Tenoyo Evi Cahyaningrum FA Elang Pujangga Fadhila, Melaila Nurul Fanny, Nabilatul Fansisca Rindu Ananta Fany Dwi Yulianti Farras Fatikhatul Al Mumtazzah Fatikha Aulya Rahma Marfuah Febi Yuspa Nastiti Febri Nur Hidayah Febriana Rachmawati Feni Atika Tsuroya Feni Atika Tsuroyya Fernanda Della Fitriana Amalia Al Wafi Fredericus Pramonodjati Frida Nur Wahidah Genovia Judit De Carvalho Lake Guterres Gita Laili Maulida Syarifa Hadjar Binar Panggalih Hanayu Anindya Nareswari Hendri Safitri Hidayah Indah Paramesthi Hussein Omar Savero Ika Restu Kaeksi Ikrima Ikrima Ikrima Rahmasari Ilham Ary Pangestu Indah Nur Aini Indra Agung Yudhistira Indra Hastuti Irginia Sofianthi Jihan Aulia Roiska Juwita Ramadhani Octavianingrum Karina Sella Karina Sella Juwitasari Keyzia Karinina Mutiara Bintang Kharisma Putri Cahya Ningrum Khotimah Nur Ramadhani KM. Lathifah Kumawati Rofidah Latifa Alya Khairunnisa latifah nur azizah Lelyana Sekar Rahmaputri Levina Arum Hindiani Liliek Prasetijaningsih Linda Widyaningrum Linda Widyaningrum Lintang Setyaningsih Lulu Antasari Luluk Chotimah Luluk Listyowati Luluq Apriliana Fauziah Luqyana Shifa Andaini Luthfiana Permata Bunda M. Eka Hidayatullah Maisela Arya Rahmawati Margaretha Alesandria Natasya Weka Marisca Windi Absari Maryati, Warsi Maulana Rahmadani Maya Dila Aprilia Maya Olivia Mayla Fara Azzahra Meisye Eka Saputri Meita Dwi Purwanri Melisa Rusmalasari Mellisa Intan Permatasari Miftakhul Janah Monica Setyowati Muhammad Afda Nuzula Muhammad Daffa Radithya Muhammad langlang Tahta Raharja Muhammad Luthfi Musta'in Musta'in Musta'in Musta'in Musta’in Musta’in Mutiara Syaharani Dewi Nabila Aulia Rasya Nabila Fatimatu Az-Zahra Nabila Fredlina M Nabila Meilani Nur Azzahra Nabila Meilani Nur Azzahrra Nabila Putri Sari Dewi Nabila Rahma Nur Aini Nabulatul Fanny Nadia Budi Agustina Nadia Vivin Melani Nadya Bening Putri Febriyani Nafi' Atun Najwa Choirunnisa Nanda Lina Oryza Septiviana Nara Indriani Naswa Lathifah Ainur Risma Naya Herdiana Nayla Az-zahra Wahyudi Nazwa Nur Fadhila Nazwa Rumaysa Aulia Nelia Canizio Nina Mur Sabekti Nira Putriana Nisa Wahyuningsih Nizar Athallah Nopita Cahyaningrum Nur Aini Fatna Fadilla Nur Indah Ramadhani Nurisma Mega Putri Nurma Ayu Puspita Ocha Avriela Oktaviana Eka Rahmadani Oliva Virvizat Prasastin Olivia Salma Ramadhani Oviantika Dwi Safitri Paramita Inka Piana Astuti Pramai Sheila Eka Khoireina Pramesti Listanto Puguh Ika Listyorini Rahaju Muljo Wulandari Rahaju Muljo Wulandari Rahayu Kurniadew Rahayu, Septi Rahmdani Eva Nur Salma Ratih Pujiastuti Ratnasari Nur Rohmah Reggy Orlando Resita Aprilia Sandhi Resti Ayu Wahyuningsih Revalina Aulia R Rina Fitriani Rizka Fellithia Rohmad Nur Huda Rohmat Nur Salim Rosa Adelia Anhar Sabrina Fadilah Diana Danifah Safira Aurelia Wulandari Salsabila Audrina Putri Salsabila, Rara Nur Salsabilla Fauziyah Salwa Ramadanni Saryadi Saryadi Saryadi Sekar Citra Prasetya Sekar Keriswanie Septi Puspita Kurniawati Setiawan Wisnu Aji Shafa' Luthfiana Widya Susanti Shelina Dwi Ambarwati Sherli Olivia Khairatunisa Shonza Affina S Silvia Nur Anggraini Sinta Nabela Siska Anggraini Yudha Pertiwi Sonia Putri Sonia Renata Reva Sovie Hidayatun N Sri Wahyuningsih Nugraheni Sri Widodo Steffy Desiandra Puteri Suci Rahmawati Syafira Ayu Damayanti Syilvana Agustina Dewi Wulandari Tasbita Anit Sulastri Tessalonika Ersaputri Tiara Pratiwi Tirla Puspita Dewi Titin Syahwarani Tri Yuniarti Tyara Avrilyanti Ghea Indriansyah Udi Budi Harsiwi Udi Budi Harsiwi Vanesha Bilqis Nur Faiz Vania Nabila Arisanti Via Aulia Ramadani Virgiana Amanda Dwi Herlina Widia Nur Fatimah Winda Nafisha Wulan Dwi Utami Wulan Indriani Yeni Nurmalitasari Yogheswaran Gopalan Yogi Khoirunnisa Sabila Yulianing Sukma Yuna Julia Choirunisa Zahra Adinda Prabawati Sulendro Zahra Aninda Zalianti Zahra Aulia Fauziah Zal Sabilla Putri Febrianti Zurni Faulina