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Pengaruh Pola Makan terhadap Kejadian Karies Gigi Anak Akmal Alif Muzakki; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 2 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i2.2354

Abstract

Dental caries is a dental tissue disease characterized by tissue damage, starting from the surface of the tooth (grooves, fissures, and interproximal areas) extending towards (Braurer). Cariogenic foods are foods that can cause dental caries. The nature of cariogenic foods is that they contain lots of carbohydrates, are sticky and break down easily in the mouth. The purpose of this article is to determine the effect of food type, food frequency, and amount of food on the incidence of dental caries. The research method used was a literature review of various current scientific literature, including journals, textbooks and research articles. According to the results of research conducted by Febrian, et al., (2015), it shows that there is a significant relationship between types of cariogenic snacks and the incidence of caries. There is an influence of food frequency on the occurrence of dental caries in children. The amount of food consumed by a person or group of people at a certain time can trigger bacteria in the oral cavity to produce acid, causing the pH of saliva to decrease and demineralization to occur which will last for 30 to 40 minutes after eating.
Pengaruh Kesakitan pada Nefron Terhadap Terjadinya Penyakit Gagal Ginjal Elsa Trisna Sari; Nur Aini Fatna Fadilla; Tyara Avrilyanti Ghea Indriansyah; Liss Dyah Dewi Arini
Student Scientific Creativity Journal Vol. 3 No. 2 (2025): Student Scientific Creativity Journal
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/sscj-amik.v3i2.5498

Abstract

Nephrons are the smallest functional units in the kidneys that are responsible for filtering blood, regulating fluid balance, and excreting waste through urine. When nephrons are damaged or diseased, kidney function can be significantly impaired. Nephron damage is usually caused by various factors, such as hypertension, diabetes, kidney infections, or certain drug toxicity. In the early stages, nephron damage can cause a decrease in glomerular filtration rate (GFR). As a result, metabolic waste products such as urea and creatinine accumulate in the blood, known as azotemia. Over time, progressive damage to the nephrons can trigger chronic kidney disease (CKD). In more severe cases, when most of the nephrons are no longer functioning, the kidneys lose their ability to maintain the body's homeostasis. This results in electrolyte imbalance, metabolic acidosis, and excess fluid buildup, known as end-stage renal disease (ESRD). At this stage, patients require renal replacement therapy such as dialysis or kidney transplantation to survive. Prevention of nephron damage is very important, including through the management of comorbidities such as diabetes and hypertension, adequate fluid intake, and avoiding exposure to toxic substances that damage the kidneys. Thus, the risk of kidney failure can be minimized.
Peran Asam Nukleat dalam Proses Sintesis Protein: Analisis Mekanisme DNA, RNA, dan Ribosom dalam Regulasi Genetik Amelia Putri Az Azahra; Pramesti Listanto; Khotimah Nur Ramadhani; Tyara Avrilyanti Ghea Indriansyah; Latifa Alya Khairunnisa; Liss Dyah Dewi Arini
Student Scientific Creativity Journal Vol. 3 No. 2 (2025): Student Scientific Creativity Journal
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/sscj-amik.v3i2.5501

Abstract

Nucleic acids play a vital role in the process of protein synthesis, which is the core of genetic regulation in cells. This process involves a complex mechanism of DNA, RNA, and ribosomes working in a coordinated manner. DNA (deoxyribonucleic acid) functions as a genetic blueprint that stores information for protein synthesis. Through the process of transcription, DNA is transcribed into messenger RNA (ribonucleic acid) (mRNA) in the cell nucleus. mRNA carries the genetic code to the cytoplasm, where ribosomes act as translation centers. Ribosomes, together with transfer RNA (tRNA), read the codon sequence on mRNA to determine the sequence of amino acids that will be assembled into polypeptides. This process, called translation, involves complex interactions between mRNA, tRNA, and ribosomes to ensure that the resulting protein is in accordance with genetic instructions. In addition, the role of non-coding RNA, such as microRNA and riboswitches, is also important in regulating gene expression post-transcriptionally. A deep understanding of the mechanisms of DNA, RNA, and ribosomes has opened up great opportunities in biotechnology and medicine, such as gene therapy and RNA-based drug development. Thus, the analysis of the role of nucleic acids becomes an important foundation in the exploration of molecular biology and genetics.
Potensi Pangan Fermentasi Tempe dalam Mengatasi Kejadian Malnutrisi Devina Adira Azzahra; Desi Rahmasari; Hanayu Anindya Nareswari; Margaretha Alesandria Natasya Weka; Rizka Fellithia; Liss Dyah Dewi Arini
Student Scientific Creativity Journal Vol. 3 No. 2 (2025): Student Scientific Creativity Journal
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/sscj-amik.v3i2.5511

Abstract

Malnutrition remains a significant public health challenge, particularly in developing countries like Indonesia. Tempeh, a fermented soybean product, is highly nutritious and has the potential to address malnutrition. The fermentation process by Rhizopus oligosporus enhances the bioavailability of essential nutrients such as protein, iron, and vitamin B12, which are crucial for growth and development. Additionally, tempeh contains natural prebiotics and probiotics that support digestive health and improve nutrient absorption. A literature review in this study indicates that regular consumption of tempeh can help improve nutritional status, particularly among vulnerable groups such as children and pregnant women. With its affordability and wide availability, tempeh serves as a sustainable food solution that can be optimized to reduce malnutrition rates in Indonesia.
Studi Toksikologi Biokimia : Dampak Senyawa Beracun Terhadap Proses Metabolisme Seluler dan Kesehatan Manusia David Valentino Iskandar; Karina Sella Juwitasari; Erlanda Islami Pasha; Elsa Trisna Sari; Liss Dyah Dewi Arini
Student Scientific Creativity Journal Vol. 3 No. 2 (2025): Student Scientific Creativity Journal
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/sscj-amik.v3i2.5520

Abstract

Biochemical toxicology studies are disciplines that study the impact of toxic compounds on biochemical processes in the human body. Toxic compounds, whether from the environment, industrial chemicals, drugs, or natural products, can interfere with cellular metabolic mechanisms and potentially cause damage to organs or body systems. This study aims to analyze how toxic compounds interact with biomolecules, such as proteins, enzymes, and nucleic acids, which play a role in cellular metabolic processes. Disruption of metabolic enzymes can affect key metabolic pathways, such as energy synthesis, detoxification, and homeostasis regulation. These toxic impacts can contribute to the development of acute and chronic diseases, including liver, kidney, nervous system disorders, and cancer. In this study, we also discuss the detoxification mechanisms involving enzymes such as cytochrome P450 and glutathione-S-transferase in reducing the toxic effects of these compounds. A deeper understanding of toxic interactions and their impact on cellular metabolism is essential in developing preventive and therapeutic strategies for poisoning or toxicity-related diseases. This research is expected to provide insight into the development of more effective drugs and medical approaches in overcoming the effects of toxic toxins on humans.
Management of Cancer in the Digestive System Liss Dyah Dewi Arini; Warsi Maryati; Puguh Ika Listyorini; Devi Pramita Sari
International Journal of Health and Medicine Vol. 1 No. 3 (2024): July : International Journal of Health and Medicine
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhm.v1i3.33

Abstract

Cancer is a non-communicable disease characterized by the presence of abnormal cells/tissues that are malignant, grow quickly and uncontrollably and can spread to other places in the patient's body. Cancer cells are malignant and can invade and damage the function of the tissue. Digestive cancer, also called gastrointestinal cancer, attacks the organs of the digestive system. Digestive cancer also includes gastrointestinal cancer, liver cancer, stomach cancer, colorectal cancer, and pancreatic cancer. Risk factors for digestive cancers are varied because many different organs can be affected. Some factors that contribute to cancer throughout the digestive system include age, heavy drinking (alcohol), smoking, and diabetes sufferers. This type of liver cancer is cancer that grows in liver cells. Liver cancer is a type of cancer that ranks second as the cancer that causes the most deaths in the world. Gastric cancer is a group of malignant diseases that have multifactorial causes, namely genetic, lifestyle and environmental factors. The symptoms caused by stomach cancer are initially not as typical as the symptoms of general digestive complaints. The diagnosis of colorectal cancer can be carried out in stages, including through an appropriate history, physical examination, and supporting examinations in the form of laboratory examinations, both from clinical laboratories and anatomical pathology laboratories. The etiology of colorectal cancer is currently still unknown. Symptoms of colorectal cancer are varied and non-specific. The main complaints of patients with colorectal cancer relate to the size and location of the tumor. Tumors in the right colon, where the contents of the colon are fluid, tend to remain hidden until they are very advanced.
Optimalisasi Pertumbuhan Bakteri Propionibacterium Acnes pada Media Nutrien Agar Nadia Budi Agustina; Nadya Bening Putri Febriyani; Piana Astuti; Tessalonika Ersaputri; Liss Dyah Dewi Arini
Intellektika : Jurnal Ilmiah Mahasiswa Vol. 3 No. 3 (2025): Intellektika : Jurnal Ilmiah Mahasiswa
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/intellektika.v3i3.2661

Abstract

Propionibacterium acnes is an anaerobic bacteria that plays an important role in dermatological research, especially in the context of skin diseases such as acne vulgaris. This study aims to optimize the growth conditions of Propionibacterium acnes in sodium media in order to increase the effectiveness of bacterial culture on a laboratory scale. The parameters tested include media pH, sodium concentration, incubation temperature, and incubation time. The research method was carried out systematically and controlled with a completely randomized design using several environmental condition treatments. The results showed that optimal growth of Propionibacterium acnes was achieved in media with a pH of 6.5–7.0, a sodium concentration of 1.5%, an incubation temperature of 37°C, and an incubation time of 72 hours in conditions without oxygen (anaerobic). By knowing the right conditions, Propionibacterium acnes bacteria can grow faster and optimally, so that it can help in dermatological research or product development related to skin health.
Efektivitas Penggunaan Pewarna Metilen Blue dalam Pengamatan Bentuk Sel pada kulit katak Azzahra Nabilla Atha; Erika Dwi Susanti; Azizah Zahra Nur Fitria; Erlanda Islami Pasha; Elsa Trisna Sari; Nur Aini Fatna Fadilla; David Valentino Iskandar; Liss Dyah Dewi Arini
Nian Tana Sikka : Jurnal ilmiah Mahasiswa Vol. 3 No. 4 (2025): Nian Tana Sikka : Jurnal ilmiah Mahasiswa
Publisher : Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59603/niantanasikka.v3i4.928

Abstract

This study aims to evaluate the effectiveness of using Methylene Blue stain in the microscopic observation of frog skin cell structures. Cell staining is an essential technique in histological studies, as it enhances the visibility of cellular components that are otherwise difficult to observe without contrast. Methylene Blue is known to have a high affinity for acidic components within the cell nucleus, thus providing a clearer depiction of nuclear and cell membrane structures. This research employed a descriptive experimental method by preparing frog skin tissue samples stained with Methylene Blue and observing them under a light microscope. The results indicated that Methylene Blue staining produced high contrast, allowing for the identification of hexagonal-shaped cells and dark, centralized nuclei. The obtained microscopic images revealed a uniform distribution of cells with clearly observable morphological structures. Therefore, Methylene Blue is proven to be effective in enhancing the microscopic visualization of epithelial tissue in frog skin and is recommended for use in both educational and basic biological research contexts.
Peningkatan Pengetahuan Ibu-Ibu Peserta Posyandu di Posyandu Salak, Celengan, Tasikmadu Mengenai Pengaruh Pasteurisasi Terhadap Jumlah Koloni Bakteri pada Susu Segar dan UHT Liss Dyah Dewi Arini; Fredericus Pramonodjati; Saryadi, Saryadi
Jurnal Pengabdian Bidang Kesehatan Vol. 3 No. 2 (2025): Jurnal Pengabdian Bidang Kesehatan
Publisher : PPNI UNIMMAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jpbidkes.v3i2.184

Abstract

Mother is a leader in a family whose duties include managing the family's healthy food and drink needs. One of the nutritious drinks that must be consumed by family members is milk. However, many family members do not understand about pasteurization or heating and non-pasteurization in cow's milk. In milk that has undergone pasteurization, the number of bacteria is less than in milk that has not undergone pasteurization. This community service activity aims to provide an understanding to the mothers of the Posyandu in Celengan, Kaling, Tasikmadu, Karanganyar villages to find out about contamination in pasteurized and non-pasteurized milk, to provide counseling to the mothers of the Posyandu about pasteurized milk and non-pasteurized milk. The counseling method is carried out using the lecture method and explanations about pasteurized and non-pasteurized milk and bacterial contamination in milk with posters and power points. The results of this community service activity are that the mothers of the Posyandu understand the differences between pasteurized and non-pasteurized milk and the presence of more bacterial contamination in non-pasteurized milk. The conclusion of this community service activity is that Posyandu mothers can learn the benefits of pasteurized milk for the body.
Optimalisasi Pertumbuhan Bakteri Propionibacterium Acnes pada Media Nutrien Agar Nadia Budi Agustina; Nadya Bening Putri Febriyani; Piana Astuti; Tessalonika Ersaputri; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 3 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i3.2691

Abstract

Propionibacterium acnes is an anaerobic bacteria that plays an important role in dermatological research, especially in the context of skin diseases such as acne vulgaris. This study aims to optimize the growth conditions of Propionibacterium acnes in sodium media in order to increase the effectiveness of bacterial culture on a laboratory scale. The parameters tested include media pH, sodium concentration, incubation temperature, and incubation time. The research method was carried out systematically and controlled with a completely randomized design using several environmental condition treatments. The results showed that optimal growth of Propionibacterium acnes was achieved in media with a pH of 6.5–7.0, a sodium concentration of 1.5%, an incubation temperature of 37°C, and an incubation time of 72 hours in conditions without oxygen (anaerobic). By knowing the right conditions, Propionibacterium acnes bacteria can grow faster and optimally, so that it can help in dermatological research or product development related to skin health.
Co-Authors Aan Riski Susanto Achsanul Ghiffari As Syafi Adelia Bekti Widyaningrum ADITYA KURNIAWAN Afrian Yohans Fernandho Agostinha Morais Assis Belo Akmal Alif Muzakki Aldona Diva Aurelia Alicia Syifa Alifah Gita Cahyani Roqimah Alifia Fara Yuliananda Alma Danita Aloysius Ekawardaya Alya Afriana Syahrani Alya Sagita Alysia Ivanda Candra Ramadhani Amalia Bintang Firshana Ambar Setiti Amelia Putri Az Azahra Amelia Putri Az Zahra Ananda Meyrika Arthama Ananda Olivia Febriyani Anang Kurniawan Anastasya Elisa Cahya Dewi Andhini Saskia Andreas Danang Saputra Angella Putri Ramadhani Anggelli Marsha Pattinama Anggraini Sih Prabandari Ani Nur Fauziah Anik Sulistiyanti Anindita Hidayatul Qolbiyah Anisa Putri Utami Anisya Candra Denvisintami Annatsa Yolantiara Mahanani Annisa Birrul Annisa Nur Agustin Annisa Yuli Kartika Sari Apriani Esma Aqila Widya Ardina Rayshabilah Ariana Agustin Ariangesty Safitri Arifatul Khoirunnisak Arinda Sumarna Ariska Sukma Romadhani Arya Listyo Adi Aryanti Putri Lestari Aryna Agustin Nur Hidayah Assyifa Friska Astrid Tyas Wardhani Aula Nafit Aurel Tata L Avelino Gomes dos Santos AYU WULANDARI Az-zhara Diah Putri Nugroho Azahra Salma Salsabila Putri Azizah Nabhila Azizah Zahra Nur Fitria Azlinatul Lulu Kharolaini Azzahra Nabilla Atha Bagus Muhamad Ridwan Bana Handaga Bangun Prajadi Cipto Utomo Bernadytha Ratriani Putri Celsi Olivia Chika Adelia Saftri Chika Muthi’atul Fadhilah Claudia Aulia Danian Pasha Pratama Darah Ifalahma David Valentino David Valentino Iskandar Della Nur’Aini Denisya Risqi Amelia Desi Rahmasari Desianti Cahya Nugraheni Devi Pramita Sari Devi Pramita Sari Devina Adira Azzahra Devina Saraswati Dhionisius David Mario Dhita Widya Ananta Dhuwi Noviyanti Dian Elizar Dinda Cinthya Nur Novalinda Dinda Daniela Sri Putri Diva Precillia Sari Dwi Ratih Rahayu Dwi Setia Ningsih Dwinanda Novitasari Echa Ananta Perdani Eka Yolanda Putri Ellen Nur Fauziah Elsa Oktavia Ramadhani Elsa Trisna Sari Eni Retnaningsih Enjeli Kurnia Safitri Erika Dwi Susanti Erlanda Islami Pasha Erma Nurhayati Firdaus Etik Yuniarsih Evanda Gita Septiana Evans Tiandra Tenoyo Evi Cahyaningrum FA Elang Pujangga Fadhila, Melaila Nurul Fanny, Nabilatul Fansisca Rindu Ananta Fany Dwi Yulianti Farras Fatikhatul Al Mumtazzah Fatikha Aulya Rahma Marfuah Febi Yuspa Nastiti Febri Nur Hidayah Febriana Rachmawati Feni Atika Tsuroya Feni Atika Tsuroyya Fernanda Della Fitriana Amalia Al Wafi Fredericus Pramonodjati Frida Nur Wahidah Genovia Judit De Carvalho Lake Guterres Gita Laili Maulida Syarifa Hadjar Binar Panggalih Hanayu Anindya Nareswari Hendri Safitri Hidayah Indah Paramesthi Hussein Omar Savero Ika Restu Kaeksi Ikrima Ikrima Ikrima Rahmasari Ilham Ary Pangestu Indah Nur Aini Indra Agung Yudhistira Indra Hastuti Irginia Sofianthi Jihan Aulia Roiska Juwita Ramadhani Octavianingrum Karina Sella Karina Sella Juwitasari Keyzia Karinina Mutiara Bintang Kharisma Putri Cahya Ningrum Khotimah Nur Ramadhani KM. Lathifah Kumawati Rofidah Latifa Alya Khairunnisa latifah nur azizah Lelyana Sekar Rahmaputri Levina Arum Hindiani Liliek Prasetijaningsih Linda Widyaningrum Linda Widyaningrum Lintang Setyaningsih Lulu Antasari Luluk Chotimah Luluk Listyowati Luluq Apriliana Fauziah Luqyana Shifa Andaini Luthfiana Permata Bunda M. Eka Hidayatullah Maisela Arya Rahmawati Margaretha Alesandria Natasya Weka Marisca Windi Absari Maryati, Warsi Maulana Charisma Ardiansyah Maulana Rahmadani Maya Dila Aprilia Maya Olivia Mayla Fara Azzahra Meisye Eka Saputri Meita Dwi Purwanri Melisa Rusmalasari Mellisa Intan Permatasari Miftakhul Janah Monica Setyowati Muhammad Afda Nuzula Muhammad Daffa Radithya Muhammad langlang Tahta Raharja Muhammad Luthfi Musta'in Musta'in Musta'in Musta'in Musta’in Musta’in Mutiara Syaharani Dewi Nabila Aulia Rasya Nabila Fatimatu Az-Zahra Nabila Fredlina M Nabila Meilani Nur Azzahra Nabila Meilani Nur Azzahrra Nabila Putri Sari Dewi Nabila Rahma Nur Aini Nabulatul Fanny Nadia Budi Agustina Nadia Vivin Melani Nadya Bening Putri Febriyani Nafi' Atun Najwa Choirunnisa Nanda Lina Oryza Septiviana Nara Indriani Naswa Lathifah Ainur Risma Naya Herdiana Nayla Az-zahra Wahyudi Nazwa Nur Fadhila Nazwa Rumaysa Aulia Nelia Canizio Nina Mur Sabekti Nira Putriana Nisa Wahyuningsih Nizar Athallah Nopita Cahyaningrum Nur Aini Fatna Fadilla Nur Indah Ramadhani Nurisma Mega Putri Nurma Ayu Puspita Ocha Avriela Oktaviana Eka Rahmadani Oliva Virvizat Prasastin Olivia Salma Ramadhani Oviantika Dwi Safitri Paramita Inka Piana Astuti Pramai Sheila Eka Khoireina Pramesti Listanto Puguh Ika Listyorini Rahaju Muljo Wulandari Rahaju Muljo Wulandari Rahayu Kurniadew Rahayu, Istiyawati Rahayu, Septi Rahmdani Eva Nur Salma Ratih Pujiastuti Ratnasari Nur Rohmah Reggy Orlando Resita Aprilia Sandhi Resti Ayu Wahyuningsih Revalina Aulia R Rina Fitriani Rizka Fellithia Rohmad Nur Huda Rohmat Nur Salim Rosa Adelia Anhar Sabrina Fadilah Diana Danifah Safira Aurelia Wulandari Salsabila Audrina Putri Salsabila, Rara Nur Salsabilla Fauziyah Salwa Ramadanni Saryadi Saryadi Saryadi Sekar Citra Prasetya Sekar Keriswanie Septi Puspita Kurniawati Setiawan Wisnu Aji Shafa' Luthfiana Widya Susanti Shelina Dwi Ambarwati Sherli Olivia Khairatunisa Shonza Affina S Silvia Nur Anggraini Sinta Nabela Siska Anggraini Yudha Pertiwi Sonia Putri Sonia Renata Reva Sovie Hidayatun N Sri Wahyuningsih Nugraheni Sri Widodo Steffy Desiandra Puteri Suci Rahmawati Syafira Ayu Damayanti Syilvana Agustina Dewi Wulandari Tasbita Anit Sulastri Tessalonika Ersaputri Tiara Pratiwi Tirla Puspita Dewi Titin Syahwarani Tri Yuniarti Tyara Avrilyanti Ghea Indriansyah Udi Budi Harsiwi Udi Budi Harsiwi Vanesha Bilqis Nur Faiz Vania Nabila Arisanti Via Aulia Ramadani Virgiana Amanda Dwi Herlina Widia Nur Fatimah Winda Nafisha Wulan Dwi Utami Wulan Indriani Yeni Nurmalitasari Yogheswaran Gopalan Yogi Khoirunnisa Sabila Yulianing Sukma Yuna Julia Choirunisa Zahra Adinda Prabawati Sulendro Zahra Aninda Zalianti Zahra Aulia Fauziah Zal Sabilla Putri Febrianti Zurni Faulina