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All Journal ACTA VETERINARIA INDONESIANA Hemera Zoa Jurnal Sain Veteriner Veterinary Biomedical and Clinical Journal Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pusat Inovasi Masyarakat Jurnal Veteriner dan Biomedis Current Biomedicine Asian Journal of Social and Humanities Indonesian Journal of Jamu Jurnal Veteriner
Lina Noviyanti Sutardi
Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Veterinary

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Studi Kasus: Terapi Prostatitis Disertai Urolithiasis pada Anjing Lokal Diaz, Fariz Arrachman; Nurdiansyah, Rio Dwi Haryadi; Bachmid, Salma Safitri; Mufida, Anis Arifatu; May, Ng U; Purwono, Rini Madyastuti; Fitri, Arni Diana; Budiono, Novericko Ginger; Prasetyo, Bayu Febram; Sutardi, Lina Noviyanti; Anisa, Rahma
Jurnal Veteriner dan Biomedis Vol. 2 No. 1 (2024): Maret
Publisher : Sekolah Kedokteran Hewan dan Biomedis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jvetbiomed.2.1.43-47.

Abstract

Prostatitis pada anjing dapat disertai dengan urolithiasis. Keduanya dapat disebabkan oleh adanya infeksi bakteri yang masuk melalui saluran kemih. Anjing bernama Momo yang merupakan pasien RSHP IPB University datang dengan keluhan stranguria, hematuria, muntah, dan susah makan di malam sebelumnya. Pemeriksaan dilakukan dengan pemeriksaan fisik dan pemeriksaan penunjang ultrasonography (USG). Hasil pemeriksaan menunjukkan bahwa Momo menderita urolithiasis disertai prostatitis. Sediaan Cefixime, Batugin® Elixir, Meloxicam, Glucosamine, Asam Traneksamat, dan pakan Royal Canin Urinary® diberikan sebagai penanganan. Kumpulan sediaan tersebut diberikan dalam rangka terapi kausatif dan simptomatik dari kasus urolithiasis disertai prostatitis.
Effect of Bosswelic Acid On Hematological Parameters In Sprague Dawley Rats (Rattus novergicus) Induced By Cyclophosphamide Maret Daulay, Lingga Surya; Wientarsih, Ietje; Esfandiari, Anita; Sutardi, Lina Noviyanti; Asmilia, Nuzul
Asian Journal of Social and Humanities Vol. 2 No. 5 (2024): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v2i5.239

Abstract

Chemotherapy drug “cyclophosphamide (SP)” can trigger oxidative stress that causes hematotoxicity and myelotoxicity, therefore an agent that can suppress the negative effects of cyclophosphamide is needed. Boswellic acid is an herbal medicine that has anti-oxidant and anti-inflammatory effects. The aim of this study was to determine the effect of boswellic acid (BA) in hematology parameter rats induced by cyclophosphamid. Animal were allocated in to six groups, each group consists of 5 rats, the KS: healthy group, KSP: cyclophosphamide group; KSD: comparison group, and BA groups (K1;K2;K3). The treatment groups were given cyclophosphamide (SP) at dose of 150 mg/kg body weight (BW) i.p. The BA groups (K1,K2,K3) were given BA at dose of 250 mg/kg BW orally for 6 consecutive days and SP on day 1 (K1), day 4 (K2), day 6 (K3). The results showed that BA administration (K2 and K3) can help increase/maintain the amount of hematological parameters including hemoglobin, hematocrit, and erythrocytes. Administrating BA for 6 days consecutively before SP (K3) has shown best results on hematological parameters than the others including the comparison group. These results suggest that BA may have a potential herbal therapeutic agents that can mitigate cyclophosphamide-induced hematotoxicity manifestations.
The In Silico Toxicity of Serai Wangi (Cymbopogon nardus) and Mimba (Azadirachta indica anggraeni, Henny endah; Purwono, Rini Madyastuti; Sutardi, Lina Noviyanti; Mustika, Aulia Andi; Manalu, Wasmen; Andriyanto, Andriyanto
Acta VETERINARIA Indonesiana Vol. 13 No. 3 (2025): November 2025
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avi.13.3.278-285

Abstract

Natural active-ingredient-based shampoos offer an effective and eco-friendly solution for maintaining the skin and hair health of companion animals. This study aimed to predict the toxicity of phytochemical compounds from citronella oil (Cymbopogon nardus) and neem oil (Azadirachta indica) using an in silico approach with the ProTox-II platform. The analyzed compounds included limonene, farnesene, eucalyptol, menthol, oleic acid, p-cymene, indole, (9Z)-9- octadecenamide, amylbenzene, p-cresol, camphor, and dieugenol, selected based on LC-MS/MS analysis. The evaluated toxicological parameters comprised oral acute toxicity (LD50), hepatotoxicity, immunotoxicity, genotoxicity (cytotoxicity, mutagenicity, carcinogenicity), as well as nuclear receptor signaling and stress response pathways. The results revealed that p-cymene exhibited the highest toxicity (LD50 = 3 mg/kg, class I), followed by oleic acid (LD50 = 48 mg/kg, class II), whereas amylbenzene was classified as non-toxic (LD50 = 6430 mg/kg, class VI). All compounds were predicted to be non-hepatotoxic and non-immunotoxic; however, p-cymene, indole, and amylbenzene showed potential carcinogenicity. Limonene was predicted to be active against AhR, ER, MMP, and ATAD5 receptors, while dieugenol was active against nrf2/ARE, HSE, and MMP. These predictions suggest that most compounds are safe for shampoo applications, except for p-cymene, which requires further evaluation. This study provides preliminary insights for the development of safe and effective natural-based shampoos.
A comparison of the Hematology Profiles from Preventive and Curative Tests on Lissachatina fulica Snail Mucin Cream for Atopic Dermatitis Supiyani, Atin; Manalu, Wasmen; Sutardi, Lina Noviyanti; Subangkit, Mawar; Andriyanto, Andriyanto
Acta VETERINARIA Indonesiana Vol. 13 No. 3 (2025): November 2025
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avi.13.3.296-302

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin disease. Continuous use of topical NSAIDs in AD cases has been shown to cause adverse effects. Lissachatina fulica mucin (LFM) cream, a natural alternative, has been used for wound healing and can be used as a preventative or curative agent in AD. The objective of this study is to assess the efficacy of LFM cream, exploring its potential as a preventative and curative measure in AD. A total of 36 male BALB/c mice were divided into three cream dosage groups: 0%, 5%, and 10%. The two treatments were preventive and curative, and the two testing times were 0 and 5 days, with three replicates each. Mice were induced with atopic dermatitis by applying 1% DNCB to a 1x1 cm area on their dorsal area for seven days. The preventive group used LFM cream for seven days before DNCB, while the curative group used it after DNCB. Blood samples were collected on days 0 and 5 of the treatment period and analyzed using a hematology analyzer. The data were analyzed using a two-way ANOVA with GraphPad Prism 10, followed by Tukey's test at a 95% confidence level. The toxicity test confirmed that the LFM cream is non-toxic and safe for topical use. The DNCB compound 1% exhibited four main symptoms of atopic dermatitis: pruritus, erythema, excoriation, and lichenification. LFM cream was highly effective, significantly suppressing AD symptoms, with the ADSI score remaining below 2 (p<0.05). Specifically, the curative efficacy was demonstrated by a significant decrease in the ADSI score on day 5 (p<0.05). Hematological analysis revealed statistically significant differences (p<0.05) in the number of lymphocytes, neutrophils, and thrombocytes across groups. The LFM cream is effective and safe for preventative use and successfully treats acute AD at 5% concentration.
Efektivitas In Vitro Antelmintik Ekstrak Etanol Meniran (Phyllanthus niruri Linn) terhadap Heterakis gallinarum Risa Tiuria; Geby Magdalena Simanjuntak; Lina Noviyanti Sutardi
Jurnal Veteriner Vol. 26 No. 4 (2025)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19087/

Abstract

Kejadian infeksi cacing gastrointestinal ayam masih cukup tinggi dan Heterakis gallinarum adalah salah satu parasit nematoda saluran pencernaan yang sering menginfeksi ayam. Rendahnya efikasi antelmintik farmasi membuat kendala bagi pengobatan dan pengendalian kecacingan serta adanya peningkatan yang nyata dalam resistansi cacing terhadap antelmintik.  Meniran (Phyllanthus niruri Linn.) merupakan salah satu tanaman obat yang tersebar di seluruh negara tropis dan subtropis di dunia. Tujuan penelitian ini adalah untuk mengetahui efektivitas meniran sebagai antelmintik H. gallinarum secara in vitro. Cacing dewasa H. gallinarum yang segar dan aktif merupakan sampel yang digunakan dan rancangan acak kelompok sebagai rancangan percobaan dalam studi ini.  Cacing H. gallinarum ditempatkan di cawan petri yang berisi dua cacing dewasa untuk setiap perlakuan yang diulang tiga kali.   Kelompok perlakuan ekstrak etanol meniran pada dosis 250 μg/mL, 500 μg/mL, dan 1000 μg/mL yang digunakan untuk pengamatan motilitas dan mortalitas H. gallinarum. Larutan NaCl 0,9% digunakan sebagai kelompok kontrol negatif, sementara antelmintik Albendazol 500 μg/mL digunakan sebagai kelompok kontrol positif. Semua dosis ekstrak etanol meniran mengakibatkan kematian H. gallinarum pada jam kedua setelah paparan. Pada kontrol positif, H. gallinarum mati pada jam keempat setelah paparan akan tetapi H. gallinarum tetap hidup hingga jam ke empat setelah paparan pada kontrol negatif. Dosis ekstrak etanol meniran 250 μg/mL, 500 μg/mL dan 1000 μg/mL mempunyai efektivitas sebagai antelmintik terhadap H. gallinarum. Akan tetapi, efektivitas ekstrak etanol meniran sebagai antelmintik paling nyata diperlihatkan pada dosis 500 μg/mL.  
Pemetaan Digital Wilayah Sebaran Stunting di Desa Suniarsih, Kabupaten Tegal Nisa, Kamilatun; Afifah, Nina Indria; Marsha, Shabrina; Afrizal, Deni; Ahadiah, Shabrina Rizki; Ramadhan, Dhiya Puja; Nurmahfuzhah, Nisrina; Sutardi, Lina Noviyanti; Prajanto, Guna
Jurnal Pusat Inovasi Masyarakat Vol. 4 No. 2 (2022): Oktober 2022
Publisher : Direktorat Pengembangan Masyarakat Agromaritim, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jpim.4.2.31-39

Abstract

Stunting di Indonesia hingga saat ini masih menjadi isu nasional karena dampaknya terhadap keberlangsungan kualitas sumber daya manusia, tak terkecuali di Desa Suniarsih, Kabupaten Tegal. Program yang diinisiasi pada kegiatan Kuliah Kerja Nyata Tematik (KKN-T) ini bertujuan untuk membantu optimalisasi kinerja posyandu dan validasi data stunting melalui pemetaan digital sebagai upaya mempermudah penanganan kejadian stunting di Desa Suniarsih, Kabupaten Tegal. Kegiatan ini dilaksanakan melalui observasi dan wawancara pada 16 keluarga dengan balita stunting yang diambil melalui teknik random sampling dari empat wilayah posyandu di Desa Suniarsih, Kabupaten Tegal. Berdasarkan hasil observasi dan wawancara kemudian dilakukan pengolahan data menggunakan WHO anthro. Hasil tersebut kemudian digunakan sebagai bahan untuk pemetaan digital wilayah persebaran kasus stunting di Desa Suniarsih dilakukan di 16 titik lokasi yang terpilih.
PELATIHAN PEMBUATAN JAMU TERNAK UNTUK DOMBA DI AL-BAROQAH FARM KECAMATAN DRAMAGA, KABUPATEN BOGOR: Jamu Ternak Bayu Febram Prasetyo; Rini Madyastuti Purwono; Lina Noviyanti Sutardi; Anisa Rahma; Baharun Rasyid
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 6 No. 4 (2025): Volume 6 No 4 Tahun 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v6i4.48460

Abstract

Kesehatan ternak merupakan aspek krusial dalam mendukung keberhasilan usaha peternakan, khususnya pada sektor peternakan domba. Namun ketergantungan peternak terhadap obat-obatan sintetis masih tinggi, yang berdampak pada biaya produksi dan risiko resistensi antimikroba. Untuk mengatasi permasalahan ini, dilakukan kegiatan pengabdian kepada masyarakat berupa pelatihan pembuatan jamu ternak berbahan herbal lokal sebagai alternatif pengobatan alami. Kegiatan dilaksanakan secara partisipatif bersama peternak mitra Al-Baroqah Farm di Kecamatan Dramaga, Bogor. Materi pelatihan meliputi pengenalan bahan herbal (kunyit, kayu manis, lada, sambiloto, dan indigofera), teknik formulasi jamu fermentasi, serta praktik aplikasi pada domba. Hasil kegiatan menunjukkan bahwa peternak sangat antusias dan mampu mengikuti seluruh tahapan pelatihan dengan baik. Jamu yang diformulasikan terbukti dapat meningkatkan nafsu makan, imunitas, serta produktivitas domba, sekaligus mengurangi ketergantungan terhadap obat sintetis. Pelatihan ini berhasil memperkenalkan model pemeliharaan peternakan yang sehat, ekonomis, dan berkelanjutan berbasis kearifan lokal.
Co-Authors Adi Winarto Afifah, Nina Indria Afrizal, Deni Ahadiah, Shabrina Rizki Alifin Wisnu Ananta Alpayet, Rahmat Amaq Fadholly Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Andriyanto Anggraeni, Henny Endah Anggraini, Lutvi Anisa Rahma Anisa Rahma, Anisa Anisa, Rahma Anita Esfandiari April Hari Wardhana April Hari Wardhana Ardi Sandriya Aulia Andi Mustika Aulia Andri Mustika Aulia Mustika Bachmid, Salma Safitri Baharun Rasyid Bambang Pontjo Priosoeryanto Bayu Febram Prasetyo Budiono, Novericko Ginger Christina Clarice Leksono Diah Nugrahani Pristihadi Diaz, Fariz Arrachman Dodi Darmakusuma Dodi Darmakusumah Ekowati Handharyani Elpita Tarigan Elpita Tarigan Elpita Tarigan Esti Dhamayanti Eva Harlina Fedik Abdul Rantam Fitri Ariyani Fitri, Arni Diana Geby Magdalena Simanjuntak Gunanti . Hadri Latif Hamdika Yendri Hamdika Yendri Hamdika Yendri Putra Hamdika Yendri Putra IETJE WIENTARSIH Inayati ilmi Khonsa Khonsa Kusdiantoro Mohamad Kusdiantoro Muhamad Leliana Nugrahaning Widi Leliana Nugrahaning Widi Leliana Widi Leliana Widi Lingga Surya Maret Daulay Madyastuti, Rini Maret Daulay, Lingga Surya Marsha, Shabrina May, Ng U Mufida, Anis Arifatu Muhammad Bintang Nababan, Ratna Kristiani Nabilah, Avida Shahnaz Nisa, Kamilatun Nurdiansyah, Rio Dwi Haryadi Nurmahfuzhah, Nisrina Nuzul Asmilia Nuzul Asmilia Prajanto, Guna Purohita, Adwisto Saktika Rachmi Ridho Ramadhan, Dhiya Puja Raphaella widiastuti Ridi Arif Riki Siswandi Rindy Fazni Nengsih Rindy Fazni Nengsih Rindy Fazni Nengsih Rindy Fazni Nengsih Rini, Dian Cipta Risa Tiuria Riski Rostantinata Riski Rostantinata Rizki Rostantinata Safitri, Nadiya Santosa, Alfian Silmy Kamila Widyanti Siti Rabi’ah SM Leluala Subangkit, Mawar Supiyani, Atin Sus Derthi Widhyari Trioso Purnawarman Utami Idha Pangesti Waras Nurcholis Wasmen Manalu Wiwin Winarsih Yessy Anastasia Yusa Irarang Yusa Irarang Yusa Irarang