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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Natur Indonesia Indonesian Journal of Forestry Research Natural B JURNAL BIOLOGI INDONESIA Akuatikisle: Jurnal Akuakultur, Pesisir dan Pulau-Pulau Kecil Jurnal Akuatiklestari Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) Journal of Tropical Marine Science Akuatikisle: Jurnal Akuakultur, Pesisir dan Pulau-Pulau Kecil Jurnal Abdi Masyarakat Indonesia BIOVALENTIA: Biological Research Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Hippocampus: Jurnal Pengabdian Kepada Masyarakat AMMA : Jurnal Pengabdian Masyarakat Indonesian Science Education Journal (ISEJ) Jurnal Perikanan Indonesian Journal of Forestry Research Berita Biologi Analit: Analytical And Environmental Chemistry
Widiastuti, Endang Linirin
Universitas Lampung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Pelatihan Pembuatan Minuman Herbal untuk Immune Booster Staff Kebun Raya Liwa Di Masa Pandemi Covid-19 Setyaningrum, Endah; Widiastuti, Endang Linirin; Arifiyanto, Achmad
Hippocampus: Jurnal Pengabdian Kepada Masyarakat Vol 1 No 2 (2022): December 2022
Publisher : PUSAT PENELITIAN DAN PENGABDIAN PADA MASYARAKAT (PPPM) POLITEKNIK NEGERI SAMBAS

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (219.931 KB) | DOI: 10.47767/hippocampus.v1i2.418

Abstract

The Sars-Cov2 virus, also known as the Covid-19 pandemic, has led in a rise in the usage of immune-boosting supplement items. This situation resulted in higher prices and a scarcity of stock on the market. This program seeks to motivate and educate UPT Liwa Botanical Garden (KRL) employees about the necessity of utilizing herbs to boost body ’s immune system during the Covid-19 outbreak. The activity's target audience is workers, who interact often with tourists from various locations. Twenty persons participated, including KRL officials, Lumbok Seminung Kehati Park Managers, and KRL apprentice students. This activity takes the form of providing content, question and answer sessions, demonstrations on how to make herbal beverages, and training assessment using pre and post-test questionnaires. The results of the training implementation revealed an increase in participants' motivation and understanding of the importance of herbal functions and the skills of making herbal drinks, as evidenced by their enthusiasm in the discussion both before and after the demonstration of making herbal drinks.
PROBIOTIC CANDIDATE PROTEOLYTIC Bacillus sp. COLLECTED FROM MANGROVE OF MARGASARI, LAMPUNG Sumardi, Sumardi; Rima, Komang; Farisi, Salman; Linirin Widiastuti, Endang
Indonesian Journal of Forestry Research Vol. 8 No. 1 (2021): Indonesian Journal of Forestry Research
Publisher : Association of Indonesian Forestry and Environment Researchers and Technicians

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59465/ijfr.2021.8.1.73-82

Abstract

Intensive shrimp culture has encountered many problems, such as declining water quality through disease caused by pathogenic microbes, which affected mortality. This study aimed to determine any potential probiotic from Bacillus sp. collected from mangrove in East Lampung, which could be used to improve the cultured shrimps' proteolytic and probiotic activity. This is a descriptive research with sampling and data collection of bacteria from many samples of mangrove. Result shows 128 isolates Bacillus from which then it has arrived at five potential probiotic Bacillus sp. The study five Bacillus sp. has been isolated with potential properties for probiotic (KPP212, IP121, UJ131, UJ132, SB141). Each isolate has characteristics with proteolytic property, growth in a wide range of pH 4–10 and osmotic stress (0–6% NaCl), non-pathogenic, ability for glucose fermentation, non-motile, and has negative catalase activity. The five potential Bacillus sp. can be used as probiotics for shrimp farming.
UJI SITOTOKSISITAS TAURIN DAN EKSTRAK ETANOL MAKROALGA COKELAT DENGAN METODE BSLT (Brine Shrimp Lethality Test) Bareta, Ainun Rohmawati; Widiastuti, Endang Linirin; Nurcahyani, Nuning
Berita Biologi Vol 22 No 2 (2023): Berita Biologi
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/beritabiologi.2023.660

Abstract

Makroalga cokelat Padina australis dan Sargassum duplicatum diketahui mengandung metabolit sekunder yang bermanfaat bagi kesehatan, salah satunya sebagai bahan baku antikanker. Tujuan dari penelitian ini untuk mengetahui kandungan senyawa bioaktif yang terdapat dalam ekstrak etanol P. australis dan S. duplicatum dari perairan Pantai Dollar Beach Padada, Kec. Ketapang, Lampung Selatan dan perairan Pantai Tegal Mas, Kec. Teluk Pandan, Pesawaran, serta mengetahui toksisitas dari taurin, ekstrak etanol P. australis dan S. duplicatum dengan metode BSLT (Brine Shrimp Lethality Test). Hasil dari penelitian ini menunjukkan bahwa ekstrak etanol P. australis dan S. duplicatum mengandung saponin, steroid, alkaloid dan flavonoid. Toksisitas taurin, ekstrak etanol P. australis dan S. duplicatum tergolong dalam toksisitas rendah terhadap Artemia salina dengan nilai LC50 berturut-turut adalah 133,73 ppm, 176,95 ppm, dan 140,42 ppm.
POTENSI PRODUK ALAMI LAUT DARI EKSTRAK ETANOL Sargassum duplicatum DAN Padina australis SECARA SITOTOKSIK TERHADAP SEL HeLa Saputra, Yosi Dwi; Widiastuti, Endang Linirin; Berliana, Melisa Intan; Nurcahyani, Nuning
Berita Biologi Vol 23 No 1 (2024): Berita Biologi
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/beritabiologi.2024.661

Abstract

Salah satu penyebab utama kematian wanita Indonesia adalah kanker serviks. Pertumbuhan sel jaringan tubuh yang tidak terkendali yang berubah menjadi tumor adalah akar penyebab penyakit ini. Banyak peneliti sedang menyelidiki beragam bahan kimia alami dari habitat laut sebagai pilihan pengobatan antikanker karena pengobatan kanker serviks memiliki efek samping yang besar dan durasi pengobatan yang panjang. Makroalga merupakan salah satu organisme laut yang dapat berpotensi sebagai sumber obat alami untuk terapi kanker. Bahan aktif seperti flavonoid, alkaloid, saponin dan steroid berpotensi sebagai agen anti kanker yang diduga dapat mempengaruhi siklus sel dalam pertumbuhan kanker melalui mekanisme apoptosis. Penelitian ini bertujuan untuk menganalisis pengaruh senyawa bioaktif yang terkandung didalam ekstrak Sargassum duplicatum dan Padina australis terhadap sitotoksisitas sel kanker serviks, HeLa. Aktivitas sitotoksik terhadap sel HeLa dievaluasi dengan menggunakan metode WST-8 dengan variasi kosentrasi ekstrak etanol 62,5; 125; 250; 500; 1.000; dan 2.000 ppm. Hasil uji sitotoksik memperlihatkan bahwa ekstrak S. duplicatum dan P. australis memiliki aktivitas sitotoksik terhadap sel HeLa. Nilai IC50 Sargassum duplicatum dan Padina australis terhadap sel HeLa masing-masing sebesar 1.108,7 dan 681,1 μg/ml. Hasil penelitian mengindikasikan bahwa S. duplicatum dan P. australis mempunyai aktivitas sitotoksik melawan sel HeLa, sehingga dapat dijadikan sumber obat antikanker serviks.
PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT POTENTIAL OF EXTRACTS ETHANOL MACROALGAE Padina australis FROM TEGAL MAS ISLAND LAMPUNG Fatimah Alhafizoh; Endang Linirin Widiastuti; Nuning Nurcahyani; Ni Luh Gede Ratna Juliasih; Endah Setyaningrum
Analit : Analytical and Environmental Chemistry Vol. 9, No. 01 April (2024) Analit : Analytical and Environmental Chemistry
Publisher : Jurusan Kimia FMIPA Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/analit.v9i01.178

Abstract

In the seas of Lampung, a kind of brown macroalgae known as Padina australis is commonly seen.. Padina australis is widely used in the food industry as a gelling agent, emulsifier, thickener, stabilizer and also in the medical industry. The content of phytochemical compounds that can be developed as phytopharmaceutical agents is one of them as antioxidants. The aim of this study was to analyze the phytochemical content and potential antioxidant activity of the macroalgae Padina australis. The method used was extraction by maceration in 70% ethanol as a solvent. The phytochemical test was performed qualitatively by a color reagent test. The FTIR test was performed to analyze the functional groups of the active ingredients, while the antioxidant test used the DPPH (1,1-diphenyl-2-picrylhydrazil) method. The results obtained show that the ethanol extract of Padina australis contains chemical compounds such as saponins, steroids, tannins, alkaloids, and flavonoids. Padina australis extract shows its potential as an alternative source of natural antioxidant compounds because it is able to reduce free radicals with an IC50 value of 407.96 ppm, which is classified as very weak antioxidant activity. Further research needs to be done to obtain other concentration doses so as to get the best antioxidant activity results that can be developed clinically for health products.    
Pelatihan Pemanfaatan Tanaman Obat Untuk Peningkatan SDM Di Desa Banjar Agung Udik, Tanggamus, Lampung Nida Lidya Susanti; Endah Setyaningrum; Nuning Nurcahyani; Endang Linirin Widiastuti
AMMA : Jurnal Pengabdian Masyarakat Vol. 3 No. 11 : Desember (2024): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Community Service Program aims to provide training on using technology-based medicinal plants to improve human resources and the health of the Banjar Agung Udik village community, Tanggamus, Lampung. This activity will ultimately provide insight, knowledge, abilities, and skills to Banjar Agung Udik village residents in utilizing natural materials in the surrounding environment as health drinks. This work was conducted on Tuesday, August 6, 2024 at 08.00-12.00 WIB with targeted audience are teenagers, PKK members and men in Banjar Agung Udik village. In addition, village officials also attended this activity. The training activity began with preparing plan and dividing the tasks of the service team, preparing the tools and materials needed during the training, and determining the training schedule. The activity ended with socialization and direction on making healthy drinks based on local natural resources. The results of this activity showed that the community was enthusiastic and actively involved in participating in the health drink-making training. With ongoing training, participants are expected to have the knowledge and skills that can be used to improve the quality of health, and even support community economic needs.
Pengenalan Penyakit Leptospirosis Pada Ibu-Ibu Majelis Taklim Miftahul Jannah Kelurahan Labuhan Ratu Kecamatan Labuhan Ratu Bandar Lampung Endang Linirin Widiastuti; Yulianty; Nuning Nurcahyani; Sri Wahyuningsih
AMMA : Jurnal Pengabdian Masyarakat Vol. 4 No. 3 : April (2025): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Leptospirosis is a disease caused by the bacterium Leptoslira. Banteri that can be transmitted from animals to humans. The spread can be through the urine of infected animals Leptospirosis disease increases during floods. Labuhan Ratu urban village in Bandar Lampung is one of the urban villages affected by flooding during high rainfall. An understanding of this disease is needed by the community, especially members of Majelis Taklim Miftahul Jannah in Labuhan Ratu Village. This is to be more vigilant in dealing with floods. The pre-test results of the Community Service Participants were 63.37. The post-test results showed an increase with a score of 90. These results prove an increase in understanding of Community Service participants by 26.33 points. The existence of this service is expected that members of Majelis Taklim Miftahul Jannah, Labuhan Ratu Village can understand the knowledge about leptorspirosis disease and the information obtained can be disseminated to the community in Labuhan Ratu.  Translated with DeepL.com (free version)
Analysis of Serum Glutamate Pyruvate Transaminase (SGPT) and Serum Glutamate Oxaloacetate Transaminase (SGOT) Levels in the Blood of Rat Offspring (Rattus norvegicus) Treated with Soybean (Glycine max L.) Extract and Zinc Hafidz, Muhammad Al Hafidz; Busman, Hendri; Kanedi, M. Kanedi; Widiastuti, Endang Linirin
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 14 No. 1 (2026): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v14i1.41788

Abstract

Background: The liver is the largest metabolic organ and plays an important role in the body. Nutritional fulfilment is one factor in maintaining liver health. Liver function can be evaluated by measuring the levels of SGPT and SGOT enzymes in the blood. Soybean juice and zinc can support liver health by keeping SGPT and SGOT enzyme levels normal. Methods: This study was conducted between October and December 2024 at the Zoology Laboratory of the University of Lampung. This study used a Completely Randomized Design (CRD) included four treatment groups. Each treatment included five mice: control (K), treatment 1 (P1)- induced Soybean juice 0,6 mL/kg body weight (P2) induced Soybean 0,3 mL/kg body weight and Zinc 0,3 mL/kg body weight, and (P3) induced Soybean 0,6 mL/kg body weight and Zinc 0,6 mL/kg body weight for 14 days. Normal and homogeneous data were analyzed using analysis of variance (ANOVA) to determine whether the treatment's effect was significant. Differences were considered statistically significant at p < 0.05. Duncan's multiple interval post hoc test (=5%) was used to identify the most effective treatment. Result: Based on the results of the one-way ANOVA test with a 95% confidence interval, the average SGPT and SGOT levels in the K, P1, P2, and P3 treatments differ significantly. The average SGPT levels above show that the P2 and P3 groups experienced a significant decrease compared to the K and P1 treatments. Conclusion: Analysis of variance (ANOVA) showed that administering soya juice and zinc at an optimum dose of 1.2 mL/kg body weight can affect and maintain normal SGPT and SGOT levels.
Policy Implementation on the Standard Size of Blue Swimming Crab (Portunus spp.) Catched  on the East Coast of Lampung Rizani; Indra Gumay Yudha; Endang Linirin Widiastuti; Novita Tresiana; Indra Gumay Febryano
Journal of Tropical Marine Science Vol 9 No 1 (2026): Journal of Tropical Marine Science
Publisher : Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jour.trop.mar.sci.v9i1.7625

Abstract

The government has issued a policy on the standard size of blue swimming crabs caught to support fisheries management, but it is difficult for business actors to comply with. This study aims to analyze the implementation of the Regulation of the Minister of Marine Affairs and Fisheries No. 7 of 2024 concerning Blue swimming crab Management on the East Coast of Lampung. The research uses a qualitative approach with a case study method, with in-depth interviews, participatory observations, focus group discussions, and documentation studies. The analysis of policy implementation examines fishermen's compliance with the blue swimming crab size standards set by the government. The results of the study show that the cause of the difficulty in implementing the blue swimming crab size provisions is the limited supervision and the lack of sanctions for violations. The orientation of fishermen's behavior still focuses on profits and the limitations of fishing technology that are not selective and destructive. The government must involve all business actors in the trading chain of blue swimming crab commodities to unify perceptions and increase fishermen's understanding of sustainable fisheries management policies on the East Coast of Lampung.
Pembuatan Jamu Kunyit Asam Dengan Komposisi Bahan Dasar Yang Berbeda Untuk Kesehatan Tubuh Bagi Ibu-Ibu PKK RT 04 Kelurahan Labuhan Ratu Bandar Lampung Yulianty; Endang Linirin Widiastuti; Nuning Nurcahyani; Enur Azizah; Primasari Pertiwi
AMMA : Jurnal Pengabdian Masyarakat Vol. 5 No. 5 : Juni (2026): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Turmeric is a plant with numerous health benefits. The most commonly used parts are the rhizome and the leaves. Generally, people use the rhizome as a cooking spice. Given the curcumin content in turmeric rhizomes, it should be developed into health-promoting beverages, such as Turmeric and Tamarind Jamu. This herbal drink is excellent for maintaining health, so the community in RT 04 Labuhan Ratu, Bandar Lampung, needs training in making Turmeric and Tamarind Jamu. The well-balanced composition of Turmeric and Tamarind Jamu can provide benefits by adding a refreshing flavor. Following the training on making Turmeric and Tamarind Jamu, there was an increase in knowledge among the participants. The initial pre-test score was 62.5 and after the training, the post-test score increased to 85. This represents an increase of 22.5 points.
Co-Authors ', Sutyarso Abdullah Aman Damai Agata, Annisa Agus Budi Utomo Agus Setyawan Alhafizoh, Fatimah Ardiansyah, Budi Khoiri Arifiyanto, Achmad Arlanda, Revilarita Azizah, Enur Berliana, Melisa Intan Elfa Verda Puspita Endah Setyaningrum Endah Setyaningrum, Endah Endang Nurcahyani Erna Rochana Ernawiati, Eti Fadilah Suci Farisi, Salman Fatimah Alhafizoh Gina Dania Pratami, Gina Dania Gita Puspitasari Hafidz, Muhammad Al Hafidz Hartoyo Hartoyo Hendri Busman Henni Wijayanti Henni Wijayanti Maharani Indra Gumay Febryano Indra Gumay Yudha Juliasih, Ni Luh Gede Ratna Kanedi, M. Kanedi Khairunnisa, Indah Khasana, Devi Ardiyati Khoirunisa Komang Rima Kresna Tri Dewi Leni, Yusyam Lestari, Sepnina Like Lia Anggraini Lili Chrisnawati Marlinda, Henny Mastuti Widianingsih Maya Riantini, Maya Nababan, Yolanda Ni Luh Gede Ratna Juliasih Nida Lidya Susanti Nita Sari Novita Tresiana Novriadi Novriadi Nugroho Ekowati, Christina Nuning Nurcahyani Nurafiah, Eva Nursafitri, Umy Pamungkas, Galuh Rara Primasari Pertiwi Putri Dara Yunda Qadar Hasani Radella Hervidea, Radella Rikha Aryanie Surya Rima, Komang Rizani Rohmawati Bareta, Ainun Romaskila, Ulfanida Roselyn, Arini Pradita RR. Ella Evrita Hestiandari Salman Farisi Saputra, Yosi Dwi Sari, Mutiara Pradita Sarno Sarno Siswahyudianto Sri Murwani Sri Wahyuningsih Sumardi . Sumardi, Sumardi Supono Supono Susanto, G. Nugroho Susanto, G. Nugroho Susanto, Gregorius Nugroho Susanto, Gregorius Nurgroho Sutyarso Sutyarso , Sutyarso Sutyarso Sutyarso Tugiyono Tugiyono Tugiyono Tugiyono Tugiyono Tugiyono Yolanda Nababan Yulianty Yulianty Soeradji Yulianty Yulianty Yuni Astuti