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All Journal International Journal of Public Health Science (IJPHS) Jurnal Kebidanan Jurnal Kesehatan Lingkungan indonesia Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Medical Journal of Indonesia Jurnal Kesehatan MEDISAINS Jurnal Ilmu Keperawatan dan Kebidanan Health Notions JPKMI (Jurnal Publikasi Kesehatan Masyarakat Indonesia) Jurnal Kesehatan Reproduksi Jurnal Epidemiologi Kesehatan Komunitas Indonesian Journal of Medicine Proceedings of the International Conference on Applied Science and Health Global Health Management Journal Jambura Journal of Health Sciences and Research Jurnal Kesehatan Ibu dan Anak Jurnal Riset Kesehatan Poltekkes Depkes Bandung South East Asia Nursing Research Medica Hospitalia Health Information : Jurnal Penelitian Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Amalee: Indonesian Journal of Community Research & Engagement Pena Medika : Jurnal Kesehatan Jurnal Borneo Akcaya : Jurnal Penelitian dan Pengembangan Pelayanan Publik Jurnal Kesehatan Kusuma Husada JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA Media Penelitian dan Pengembangan Kesehatan
Suharyo Hadisaputro
Ilmu Penyakit Dalam Universitas Diponegoro Semarang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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THE EFFECT OF HOLISTIC PROGRAMS ON CORTISOL SERUM LEVELS IN POLYCISTIC OVARIUM SYNDROME Hadisaputro, Suharyo; Suwandono, Agus; Kurniawati, Erna Yovi
Indonesian Journal of Medicine Vol 4, No 4 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (368.477 KB)

Abstract

Background: The increasing prevalence of polycystic ovary syndrome (PCOS) in Indonesia reaches 8-10%. Patients with polycystic ovary syndrome are at risk of experiencing complex psychological disorders and decreased well-being. Psychological disorders in polycystic ovary syndrome are at risk of developing physical symptoms and increasing insulin resistance. The Holistic Program consists of a combination of diet yoga and remembrance therapy as an integrated holistic therapy. There is no non-pharmacological therapy that is holistically integrated to reduce serum cortisol levels in polycystic ovary syndrome. This study aimed to examine the effect of holistic programs on cortisol serum levels in polycistic ovarium syndrome.Subjects and Method: This was a randomized controlled trials conducted in Yogyakarta. A sample of 30 women patients with PCOS aged 19-40 years old was selected for this study. The sample was divided into 2 groups. The intervention group received holistic program for 14 days. The dependent variable was cortisol serum. The independent variable was holistic program. Cortisol serum and insulin levels were measure by ELISA method at the Integrated Research and Testing Laboratory, Universitas Gadjah Mada, Yogyakarta. Insulin resistance was calculated using the HOMA IR method. The data were analyzed by independent t-test and different test Paired t-testResults: Serum cortisol levels in the intervention group were lower than the control group. Serum cortisol levels decrease after the implementation of a holistic program.Conclusion: The holistic program that was carried out for 14 days in polycystic ovary syndrome is effective to reduce serum cortisol levels.Keywords: holistic program, cortisol serum, polycystic ovary syndromeCorrespondence: Erna Yovi Kurniawati. Masters Program in Applied Midwifery, School of Health Polytechnics, Ministry of Health Semarang. Jl. Tirto Agung, Pedalangan, Banyumanik, Semarang 50239, Central Java. Mobile: +6287739122352. Email: yovi.raharjanto@gmail.comIndonesian Journal of Medicine (2019), 4(4): 376-382https://doi.org/10.26911/theijmed.2019.04.04.11
PENGARUH AKUPRESUR PERIKARDIUM 6 TERHADAP MUAL MUNTAH KEHAMILAN KURANG 16 MINGGU Djanah, Nur; Hadisaputro, Suharyo; Hardjanti, Triana Sri
Jurnal Kesehatan Ibu dan Anak Vol 5 No 1 (2014): Juli
Publisher : Poltekkes Kemenkes Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.456 KB) | DOI: 10.29238/kia.v5i1.393

Abstract

Nausea and vomiting in pregnancy is a common problem, which can be serious for both mother and baby. More than half (50-90%) of pregnant women experiencing nausea vomiting. Numerous attempts have been made to reduce the nausea vomiting with pharmacological and nonpharmacological approaches. Acupressure Pericardium 6 is one of the non-pharmacological approach, which is related closely to acupuncture, is considered as a key point in reducing the symptoms of nausea and vomiting, but some studies show contradictory results. The purpose of this research was to describes the effect of acupressure Pericardium 6 to decrease the frequency of nausea vomiting of pregnancy less 16 weeks.The design used was randomized pre-post test control group design. Total sample 33 consists of 17 intervention group and 16 control group, who meets the criteria of inclusion and exclusion. The mother?s age, gravidity, obesity levels and hiperemesis gravidarum history matched between groups. The intervention group were given a treatment of acupressure on acupoint Pericardium 6, while the control group acupressure on three fingers on top of acupoint Pericardium 6, it was done every 5 minutes for four days. There are significant differences on decreases of the duration of nausea (p = 0.002) and episodes of nausea vomiting (p = 0,015) between the intervention group and control group after intervention, while episodes of retching vomiting there are no significant differences (p = 0,159). The conclusion was that the acupressure Pericardium 6 can decreases of the frequency of nausea vomiting of pregnancy. Acupressure Pericardium 6 can be applied as a non-pharmacological therapy to decrease frequency of nausea vomiting in pregnancy less than 16 weeks.
Long Bean Leaf Extract for Improving Haematological Status of Female Adolescent with Anemia that Gets Fe Supplementation Nurjanah, Fatihah Wari; Hadisaputro, Suharyo; Fatmasari, Diyah
KEMAS: Jurnal Kesehatan Masyarakat Vol 16, No 1 (2020)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v16i1.23203

Abstract

The incidence of anemia among female adolescent in Indonesia is 48.9%, due to menstruation, poor nutrition intake and worm investment. Long-term effects of anemia in female adolescent can occur stunting. Pharmacological anemia management by taking Fe supplements but these supplements can cause nausea. Nausea can be avoided by non-pharmacological anemia treatment by consuming Fe-containing foods such as long bean leaves. Long bean leaf contains Fe which can accelerate the absorption process of it in the body. The objective of the research was to analyze the effect of long bean leaf extract on changes in anemia status of female adolescent given Fe supplementation. Quasy experiment research design with pretest posttest with control group design. Data was collected for 14 days with 38 respondents. The treatment group was given 200 mg / day long bean leaf extract and Fe supplement, while the control group was given Fe supplement. Hemoglobin, hematocrit and erythrocyte levels were measured before and after the intervention. Data analysis used paired and independent sample t tests. The results showed the treatment group experienced increased levels of hemoglobin, hematocrit and erythrocytes by 1.45 gr / dL (p: 0.02), 3.61% (p: 0.019) and 0.53 x 106 / µl (p: 0.013 ). 200 mg / day long bean leaf extract given to young women with anemia who received iron supplementation for 14 days improved hematological status as indicated by an increase in hemoglobin levels, hematocrit and erythrocyte counts.
BERBAGAI FAKTOR RISIKO KEJADIAN TB PARU DROP OUT ( Studi Kasus di Kabupaten Jepara dan Pati) Himawan, Ari Budi; Hadisaputro, Suharyo; Suprihati, Suprihati
Jurnal Publikasi Kesehatan Masyarakat Indonesia Vol 2, No 1 (2015): April 2015
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpkmi.v2i1.2711

Abstract

AbstrakTB masih menjadi beban yang tinggi bagi masalah kesehatan di Indonesia yang menduduki peringkat ke-4 dunia dalam kejadian TB. Drop out merupakan salah satu penyebab terjadinya kegagalan pengobatan yang meningkatkan kemungkinan terjadinya MDR TB. MDR TB memerlukan biaya pengobatan lebih banyak dan waktu yang lebih lama. Tujuan penelitian adalah untuk menjelaskan pengaruh karakteristik individu dan lingkungan sebagai faktor risiko kejadian TB DO.Penelitian ini dilakukan secara observasional analitik dengan desain kasus kontrol dengan ditunjang analisa kualitatif. Jumlah subyek 70 orang, dengan rincian 35 kasus TB DO dan 35 kontrol( menyelesaikan pengobatan) yang tercatat antara tahun 2012-2013, dipilih secara consecutive sampling. Analisis data secara bivariat dengan uji chi Square dan multivariat dengan uji regresi logistik.Faktor risiko kejadian TB DO yang terbukti yaitu kurangnya pengetahuan tentang TB ( OR =78,6, 95% CI=11,697-528,218 ,p=0,000), pengalaman merasakan ESO ( OR=6,338, 95% CI=1,279-31,420,p=0,024), dan menggunakan obat tradisional (OR=7,451, 95% CI=1,315-42,209, p=0,023). Variabel yang tidak terbukti adalah umur, jenis kelamin, pekerjaan, penghasilan, tingkat pendidikan, akses menuju tempat pengobatan).Faktor risiko kejadian TB DO adalah kurangnya pengetahuan tentang TB, pengalaman merasakan ESO dan menggunakan obat tradisional. Kata-kata Kunci : TB DO, Efek samping obat, obat tradisional AbstractTuberculosis is still a high burden for health problems in Indonesia, which was ranked 4th in the worl . Drop out TB treatment was noted as one of the causes  that related to treatment failure, which is more risk to be MDR. MDR TB treatment will take more cost and time to cure it . The purpose of study was to investigate the risk factors, individual characteristics and environment, for incidence of TB DO. The study using analytic observational case-control design and enhanced by qualitative analysis. There are 70 subjects consists  of 35 cases of TB defaulter and 35 controls (complete treatment ) that reported between 2012 and 2013, consecutive sampling was used to selected respondent. Bivariate analysis using chi Square test and logistic regression for multivariate analysis. Multivariate analysis show that risk factors for TB DO include  lack of knowledge about TB ( OR = 78.6 , 95 % CI = 11.697 to 528.218 , p = 0.000 ) , the experience drug side effect ( OR = 6.338 , 95 % CI = 1.279 to 31.420 , p = 0.024 ) , and using traditional medicine (OR = 7.451 , 95 % CI = 1.315 to 42.209 , p = 0.023 ) . Elder age , sex male , occupation , lower income , level of education and access were not associated for TB DO. Risk factors for  TB DO is a lack of knowledge about TB , the experience side effect medicine and using traditional medicine . Keywords : TB DO , side effect of drug , traditional medicine
FAKTOR RISIKO KEJADIAN HIV DAN AIDS PADA REMAJA 14-24 TAHUN Arfan, Iskandar; Hadisaputro, Suharyo; Anies
JURNAL BORNEO AKCAYA Vol 2 No 1 (2015): Jurnal Penelitian dan Pengembangan Pelayanan Publik
Publisher : Badan Penelitian dan Pengembangan Provinsi Kalimantan Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51266/borneoakcaya.v2i1.82

Abstract

Abstract. Adolescents are associated with risky activities so as to be a group at risk for HIV infection. Associated with the course of HIV infection, can be understood if the infection usually begins when adolescence. The purpose of this study was to prove the influence of the host and environmental factors that influence the incidence of HIV and AIDS in adolescents 14-24 years of age. The design was used a case-control design and reinforced with qualitative studies with the number of respondents was 110 respondents, including 55 cases and 55 controls, were selected by purposive sampling attention to inclusion and exclusion criteria. Quantitative data were collected by questionare interview, qualitative data were collected by indepth interview. Analysis of bivariate data using a chi-square test and multivariate data using logistic regression. Factor that proved to affect the incidence of infection HIV and AIDS in adolescents 14-24 years is risky behavior (unprotected sex) (OR = 12.41 and 95% CI = 3.37-45.71), the communication of parents (OR = 11 , 66 and 95% CI = 4.24- 32.07). The analysis also shows that if adolescents experience both of the above, then the chances of being infected with HIV and AIDS is equal to (86%). Factors that are not proven effect is education, residency status, risky behaviors (drug injection), the use of media television/handphone (see porn picture or video), the use of the Internet media (see porn picture or video), the condition of the parents (parents of adolescents in the context complete and not divorce or dead), parental supervision, relationship with parents, peer pressure (sex) and pressure peer (injectable drugs). Risk factors for the incidence of HIV and AIDS among adolescents 14-24 years is risky behavior (unprotected sex) high and communications poor parents, Adolescent expected to always understand about (HIV and AIDS, reproductive health, n drug) to avoid unsafe sex and fill leisure time with sports and positive behaviour. Parents / families are also expected to have knowledge about (HIV and AIDS, reproductive health, n drug) establish communication, attention, rules and open to discuss problems of children.
Analisis Faktor Risiko yang Berpengaruh Terhadap Kejadian Keracunan Pestisida Organofosfat pada Petani Penyemprot Hama Tanaman di Kecamatan Bulu, Kabupaten Temanggung, 2002. Mualim, Khabib; Setiani, Onny; Hadisaputro, Suharyo
Jurnal Kesehatan Lingkungan Indonesia Vol 1, No 2 (2002): OKTOBER 2002
Publisher : Master Program of Environmental Health, Faculty of Public Health, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkli.1.2.56 - 60

Abstract

ABSTRACT Background : Pesticides spraying which does not follow the regulation, will give many effect to human health. For example, the farmers will be Poisoning Pesticides Poisoning can be found by the examination of the blood cholinesterase activities. The factor that influence to the occurrence of pesticides poisoning are factors from the inside of the human body (internal) and the outside of the human body (external). Based on the result of examination of the farmer’s blood cholinesterase activities  that had been carried on  for four  times, it showed that in year 1994, 58.4% from 65 person were Poisoned; in year 1997, 36.3% from 85 person were Poisoning in year 1999, 30.7% from 80 person were Poisoning, in year 2000, 65.3% from 80 persons were Poisoned. Methods : Research design used case-control study with 104 cases and 104 controls. Risk factors were the  research area,  age, nutritional status, anemia, pesticides processing, using of personal protective equipment, pesticides dose, the number of pesticides used, work duration, spraying duration, spraying frequency, spraying action in the same wind direction, and spraying time. The research was carried on in the  sub district of Bulu, district of Temanggung, Central Java. Results : the number of Poisoning occurences in Pakurejo village are 30.3%, age group of 30 – 39 years are 30.8%  and  SD Graduation 59.1%. Risk factors that influence to the occurrence of pesticides Poisoning are  nutritional status < 18.5 (OR = 6.78; 95% CI = 2.08 – 22.62); not properly  pesticides dose (OR = 6.46; 95% Cl = 2.52-16.57); the number of pesticides types ³ 3 types (OR = 5.37; 95% Cl = 2.23-12.92); anemia (OR = 5.03; 95% Cl = 1.54-16.46); spraying frequency ³ 3 times (OR = 4.95; 95% Cl = 2.03-12.7); bad sprying times (OR = 3.94; 95% Cl = 1.70-9.17); age ³ 40 year (OR = 3.83; 95% Cl = 1.64-8.94); sprying action opposites the wind direction (OR = 3.43; 95% Cl = 1.37-8.62); and using of un complete personal protective equipment (OR = 2.83; 95% Cl = 1.19-19.68). Conclusion, nutritional status risk factor < 18.5 is the most influenced risk factor to the occurrence of organophosphate pseticides Poisoning at the sprayer farmers of plant pest. Key Word: Rick factors, Cholinesterease activities, Organophosphate Pesticides poisoning
High Ultrafiltration Increasing Intradialytic Blood Pressure on Hemodialysis Patients Armiyati, Yunie; Hadisaputro, Suharyo; Chasani, Shofa; Sujianto, Untung
South East Asia Nursing Research Vol 3, No 1 (2021)
Publisher : University of Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/seanr.3.1.2021.8-15

Abstract

The increase in blood pressure when the patient is undergoing hemodialysis is experienced by patients with intradialytic hypertension. This condition can be very dangerous for the patient, must be prevented and needs to be controlled. Prevention can be done by controlling variables that can affect intradialytic blood pressure, including ultrafiltration during hemodialysis. This study aims to analyze the relationship between ultrafiltration (ultrafiltration goal, ultrafiltration rate) and intradialytic blood pressure. This research was a descriptive-analytic study with a cross-sectional design, with 112 samples at two centres of dialysis in Semarang. Data were analyzed using the Spearman Rho. The finding obtained showed that ultrafiltration goal (UFG) and ultrafiltration rate (UFR) correlated with intradialytic blood pressure (systolic, diastolic and mean arterial pressure). The magnitude of UFG an associated with increase in intradialytic systolic (p=0,024; r=0,213), increase in intradialytic diastolic (p=0,007; r=0,252) and increase in mean arterial pressure (p=0,016; r=0,227). High UFR is associated with with increase in intradialytic systolic (p=0,037; r=0,211), increase in intradialytic diastolic (p=0,001; r=0,320) and increase in mean arterial pressure (p=0,034; r=0,200). Determination of ultrafiltration during hemodialysis must be done carefully and precisely to prevent an increase in intradialytic blood pressure.
EFEKTIVITAS FOOT HAND MASSAGE TERHADAP RESPON FISIOLOGIS DAN INTENSITAS NYERI PADA PASIEN INFARK MIOKARD AKUT : STUDI DI RUANG ICCU RSUD.DR. ISKAK TULUNGAGUNG Hariyanto, Awan; Hadisaputro, Suharyo; -, Supriyadi
Jurnal Ilmu Keperawatan dan Kebidanan Vol 7, No 3 (2015): Desember 2015
Publisher : Jurnal Ilmu Keperawatan dan Kebidanan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar Belakang : Infark miokard akut (IMA) terjadi kerusakan jaringan jantung akibat kekurangan suplai oksigen menimbulkan nyeri dada, nyeri ini dapat menyebabkan frustasi dan penurunan kualitas hidup. Berbagai intervensi dapat dilakukan untuk mengatasi nyeri dada baik dengan farmakologis dan non farmakologis, salah satu intervensi nonfarmakologis adalah foot hand massage. Metode : Desain penelitian ini menggunakan  Randomized Pretest-Postest Control Group Design. Pengambilan sampel dengan simple random sampling besar sampel  36 responden terdiri 18 kelompok perlakuan dan 18 kelompok kontrol. Analisis data secara univariat dengan table distribusi frekuensi dan analisis bivariat dengan paired t-test, wilcoxon untuk kelompok berpasangan, untuk kelompok tidak berpasangan menggunakan independen t-test, mann-whitney dengan taraf signifikansi ≤ 0,05 Hasil: Foot hand massage berpengaruh terhadap respon fisiologis nyeri ( kelompok berpasangan ) p-value: tekanan darah systole  0,001 diastole 0,004, nadi 0,004, respirasi 0,001, suhu 0,059, lekosit 0,001, intensitas nyeri 0,001. Kelompok tidak berpasangan sesudah perlakuan p-value : tekanan darah sistole 0,034, diastole 0,010 nadi 0,001, respirasi 0,024, suhu 0,557, lekosit 0,019, intensitas nyeri 0,001. Simpulan: Pasien infark miokard akut yang diberikan foot hand massage selama 4 kali 20 menit dalam 2 hari bersama dengan pengobatan standart dapat memberikan respon fisiologis nyeri pada tekanan darah sistole, diastole, nadi , respirasi, lekosit darah dan pada kelompok perlakuan 94% intensitas nyeri menurun skala ringan, tapi tidak berespon terhadap suhu. Saran: Foot hand massage sangat efektif dan dapat digunakan sebagai salah satu intervensi keperawatan non farmakologi untuk mengatasi nyeri infark miokard akut Kata Kunci : Foot Hand Massage, Nyeri, Infark Miokard Akut
Factors Contributing to Intradialytic Hypertension in Hemodialysis Patients Armiyati, Yunie; Hadisaputro, Suharyo; Chasani, Shofa; Sujianto, Untung
South East Asia Nursing Research Vol 3, No 2 (2021)
Publisher : University of Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/seanr.3.2.2021.73-80

Abstract

Intradialytic hypertension (IDH) is the most common complication of hemodialysis patients in Indonesia. It must be controlled, to maintain the patient's quality of life and prevent worsening conditions. Some factors affecting IDH include predialysis fluid overload characterized by excessive interdialytic weight gain (IDWG), low adherence to fluid restriction and increased ultrafiltration during haemodialysis. The study aims to identify contributing factors of IDH. A case-control design was used in this study. A purposive sampling technique was used to recruit 92 samples at two centres of dialysis in Semarang, which was divided into case group (n=46) and control group (n=46). Data were analyzed using the Chi-square test by calculating Odds Ratios (OR). The finding showed that excessive IDWG (p=0,000, OR=16.95, 95% CI:5,56-51,65), low fluid adherence (p=0,001, OR=4,41, 95% CI:1,82-10,68) and excessive ultrafiltration (p=0,000, OR = 29,52, 95% CI:9,23-94,46) showed significant result. However, the incidence of IDH was not correlated with sex, age and length of haemodialysis. A greater increase in interdialytic weight requires lower fluid and higher ultrafiltration factors must be controlled precisely because those are considered as the risk factors for the high incidence of IDH. Excessive ultrafiltration is the most dominant risk factor in the high incidence of IDH.
Pengaruh Vitamin D terhadap Faktor Metabolik pada Perempuan dengan Sindroma Ovarium Polikisitik (SOPK): Systematic Review - Meta Analysis Andriana, Andriana -; Hadisaputro, Suharyo; Santjaka, Aris
Amalee: Indonesian Journal of Community Research and Engagement Vol 3 No 2 (2022): Amalee: Indonesian Journal of Community Research and Engagement
Publisher : LP2M INSURI Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/amalee.v3i2.2759

Abstract

Deficiency of Vitamin D is one of the causes of Polycystic Ovary Syndrome (PCOS). Vitamin D deficiency can affect metabolic factors in women with PCOS. The purpose of this study was to analyze the effect of vitamin D on the metabolic factors of women with PCOS. The method used is the Systematic Review-Meta Analysis study design. The databases used for searching articles are Sciencedirect, PubMed, and Proquest. Keywords combined with Boolean Operators Inclusion criteria: publications with RCT designs from 2015 to 2020, women aged 18 to 49 years with PCOS, type of vitamin D intervention. Outcomes measured were levels of FPG, insulin, triglycerides, total kolesterol, LDL, HDL, and HOMA-IR. The results of the research where 12 studies were analyzed because they met the eligibility criteria. Administration of vitamin D significantly affected total kolesterol (WMD, -7.94; 95% CI, -15.74 to -0.13, P = 0.05), and HDL (WMD, ̶ 3.24; 95% CI, ̶ 4.32 to ̶ 2.16, P < 0.00001). Vitamin D intervention had no significant effect on FPG, insulin, triglycerides, LDL, and HOMA-IR levels. The conclusions from this study stated that Vitamin D influenced total kolesterol and HDL levels. Defisiensi Vitamin D merupakan salah satu penyebab terjadinya Sindrom Ovarium Polikistik (SOPK). Defisiensi vitamin D dapat mempengaruhi faktor-faktor metabolik pada perempuan yang mengalami SOPK. Tujuan penelitian ini untuk menganalisis pengaruh vitamin D terhadap faktor metabolik perempuan dengan SOPK. Metode yang digunakan yaitu Desain studi Systematic Review-Meta Analysis. Database yang digunakan untuk pencarian artikel adalah Sciencedirect, PubMed, dan Proquest. Kata kunci dikombinasikan dengan Boolean Operators Kriteria inklusi: publikasi dengan desain RCT tahun 2015 sampai 2020, perempuan usia 18 sampai 49 tahun dengan SOPK, jenis intervensi vitamin D. Hasil yang diukur adalah kadar FPG, insulin, triglycerides, total kolesterol, LDL, HDL, and HOMA-IR. Hasil penelitiannya adalah 12 studi dianalisis karena memenuhi kriteria kelayakan. Pemberian vitamin D berpengaruh secara signifikan terhadap kadar total kolesterol (WMD, -7.94; 95% CI, -15.74 to -0.13, P = 0.05), dan HDL (WMD, ̶ 3.24; 95% CI, ̶ 4.32 to ̶ 2.16, P < 0.00001). Intervensi vitamin D tidak berpengaruh secara signifikan pada kadar FPG, insulin, triglycerides, LDL, dan HOMA-IR. Simpulan dari penelitian ini dinyatakan bahwa Vitamin D berpengaruh terhadap kadar total kolesterol dan HDL.
Co-Authors Abdul Ghofur Adam, Oktaviana Thresia Monika Barbara Ag Soemantri Agus Suwandono Agustinus Soemantri Amin, Dewita Rahmatul Andriana, Andriana - Ani Margawati Anies Anies Anies Annastasia Ediati Arfan, Iskandar Ari Budi Himawan Ari Suwondo Aris Santjaka Astuti, Ismi Puji Awan Hariyanto, Awan Ayu Diana Meilantika Azzahra, Ilya Nur Aulia Bagoes Widjanarko Banundari Rachmawati Dilla, Tasya Nurlaila Diyah Fatmasari Djamaluddin Ramlan, Djamaluddin Djokomoeljanto Djokomoeljanto Dwi Pudjonarko Eny Retna Ambarwati Fajri, Umi Nur Fara, Yetty Dwi Farah Salsabila, Farah Ganda Gumilar, Argo Gumilar, Argo Ganda Gustiya, Sherly Dwi Hadi Hadi Hamdan, Yusuf Lensa Harfaina, Harfaina Haryono, Nathasia Elga Henry Setyawan Susanto Henry Setyawan Susanto Heri Nugroho Herliani, Emy Herman Kristanto Hikmah, Kholisotul Imam Djamaluddin Mashoedi Iswari Setianingsih Jaleha, Jaleha Jayawarsa, A.A. Ketut Julian Dewantiningrum K. Heri Nugroho HS, K. Heri Kamilah Budhi Rahardjani, Kamilah Budhi Khabib Mualim, Khabib Kumorwulan, Suryati Kurniawati, Erna Yovi Lestariningsih Lestariningsih Lukmono, Djoko Trihadi Maria Mexitalia Mateus Sakundarno Adi, Mateus Sakundarno Melyana Nurul Widyawati Moedrik Tamam Muflihah Isnawati Muhammad Saleh Muliawati, Ratna Muzaroah Ermawati Ulkhasanah Nildawati . Noor Pramono Nur Djanah, Nur Nurjanah, Fatihah Wari Nurul Aeni Oktavia, Eva Zuli Oktaviarini, Eka Onny Setiani Pratiwi, Tia Purwanti, Sumy Hastry Pusaka, Semerdanta Rahmah, Aulia Agyanti Resty Ryadinency Rini Astuti Rini, Sulistio Roesipin, Sri Wahyuningsih Rr. Sri Endang Pujiastuti Safira, Rahma Salma, Baiq Desi Sayono Sayono Selamat Budijitno Shofa Chasani Siti Patimah Soejoenoes, Ariawan Soejoenoes, Ariawan Sofro, Muchlis AU SRI RAHAYU Sri Sumarni Sri Wahyuni Sudiyono Suprihati - Supriyadi - Supriyana Supriyana, Supriyana Suryati Kumorowulan Sutaryo Sutaryo Thaariq, Nurul Aziza Ath Tjokorda Gde Dalem Pemayun Triana Sri Hardjanti, Triana Sri Untung Sujianto Widiastuti Samekto Widjarnarko, Bagoes Yunie Armiyati