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<![CDATA[POTENSI KEANEKARAGAMAN UMUR NYAMUK Culex quinquefasciatus SEBAGAI VEKTOR FILARIASIS DI DAERAH ENDEMIS KOTA PEKALONGAN ]]>
<![CDATA[Ghofur, Abdul]]>;
<![CDATA[Hadisaputro, Suharyo]]>;
<![CDATA[Sayono, Sayono]]>;
<![CDATA[Ganda Gumilar, Argo]]>
<![CDATA[ Jurnal Kesehatan Kusuma Husada Vol. 15 No. 1, Januari 2024 ]]>
Publisher : <![CDATA[Universitas Kusuma Husada Surakarta ]]>
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DOI: 10.34035/jk.v15i1.1213
<![CDATA[Filariasis adalah penyakit menular menahun yang disebabkan oleh cacing filaria dan ditularkan melalui nyamuk (vector borne disiese). WHO menetapkan kesepakatan global sebagai upaya untuk mengeliminasi filariasis pada tahun 2020 melalui Global Programme to Eliminate Lymphatic Filariasis (GPELF), tetapi sampai tahun 2023 di Kelurahan Jenggot Kota Pekalongan masih menjadi daerah endemis filariasis dengan ditemukannya kasus baru. Nyamuk berpotensi sebagai vektor filriasis apabila memenuhi persyaratan populasi spesies yang bersangkutan secara umum mempunyai umur cukup untuk menjadi vektor masa inkubasi eksternal dari filaria. Tujuan penelitian ini adalah untuk mengetahui umur nyamuk Culex quinquefasciatus sebagai vektor filariasis di daerah Endemis Kelurahan Jenggot Kota Pekalongan. Cx. quinquefasciatus dipilih karena menjadi spesies terbanyak di daerah penelitian dan berpotensi menjadi vektor filariasis. Desain penelitian ini adalah deskriptif kuantitatif dengan menggunakan 200 sampel nyamuk betina dengan metode dilatasi ovarium. yaitu dengan membedah ovarium nyamuk untuk memeriksa parousitasnya. Selanjutnya, jumlah dilatasi dikalikan dengan siklus gonotropik nyamuk, sehingga diperoleh spesies vektor yang berpotensi sebagai penular penyakit bila dikaitkan dengan umur siklus hidup ekstrinsik parasit. Hasil penelitian didapatkan rata – rata umur nyamuk Cx. quinquefasciatus adalah 17.2 hari sedangkan masa inkubasi ekstrinsik filaria dari L1 sampai L3 adalah 10-13 hari. Dari hasil penelitian dapat disimpulkan bahwa nyamuk Cx. quinquefasciatus memiliki umur yang berpotensi menjadi vektor filariasis. Filariasis is a chronic infectious disease caused by filarial worms and transmitted through mosquitoes (vector borne disease). WHO established a global agreement as an effort to eliminate filariasis by 2020 through the Global Program to Eliminate Lymphatic Filariasis (GPELF), but until 2023 Jenggot Village, Pekalongan City, is still an endemic area for filariasis with the discovery of new cases. Mosquitoes have the potential to be vectors of filariasis if they meet the requirements for the population of the species concerned to generally have sufficient age to become a vector for the external incubation period of filariasis. The aim of this research is to determine the age of the Culex quinquefasciatus mosquito as a filariasis vector in the endemic area of Jenggot Village, Pekalongan City. Cx. quinquefasciatus was chosen because it is the most abundant species in the study area and has the potential to be a filariasis vector. The design of this research was descriptive quantitative using 200 samples of female mosquitoes using the ovarian dilatation method. namely by dissecting the mosquito's ovary to check its parousity. Next, the number of dilations is multiplied by the mosquito's gonotrophic cycle, to obtain a vector species that has the potential to transmit disease when related to the age of the parasite's extrinsic life cycle. The research results showed that the average lifespan of Cx mosquitoes. quinquefasciatus is 17.2 days while the incubation period for extrinsic filaria from L1 to L3 is 10-13 days. From the research results it can be concluded that the mosquito Cx. quinquefasciatus has the potential to become a filariasis vector.]]>
<![CDATA[POLISI LALU LINTAS DI KOTA SEMARANG BERISIKO OBESITAS ]]>
<![CDATA[Herliani, Emy]]>;
<![CDATA[Saleh, Muhammad]]>;
<![CDATA[Adi, Sakundarno]]>;
<![CDATA[Anies, Anies]]>;
<![CDATA[Widjanarko, Bagoes]]>;
<![CDATA[Hadisaputro, Suharyo]]>;
<![CDATA[Purwanti, Sumy Hastry]]>
<![CDATA[ Pena Medika Jurnal Kesehatan Vol 5, No 1 (2015): PENA MEDIKA JURNAL KESEHATAN ]]>
Publisher : <![CDATA[Universitas Pekalongan ]]>
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DOI: 10.31941/pmjk.v5i1.350
<![CDATA[Obesity is a condition due to the imbalance of calories in the body. Obesity which appears in adolescence tend to continue into adulthood, and until the elder years. The purpose of this study is to determine the influence of obesity risk factors in traffic police.Methods : The design used case-control. The number of respondents were 90, which consist of 45 cases and 45 controls, which were selected using simple random sampling. Bivariate data analysis used chi-square and multivariate used logistic regression.Results : Two variables that were significantly associated are excessive calorie intake rate (OR = 10.95 and 95% CI = 3.22 to 37.16) and lack of physical activity (OR = 3.78 and 95% CI = 1.04 to 13 ,66). If respondents possess both of the factors, chances for obesity will equal to ( 88 % ).Conclusion : Risk factors are excessive calorie intake rate and lack of physical activity. It is expected to increase the role of leaders and institutions involved in the promotion of healthy living and obesity prevention through socialization. Keywords : Obesity, risk factors, excessive calorie intake rate, lack of physical activity]]>
<![CDATA[Fetal Growth Cut-Off Point To Predict Neonatal Outcome In Pregnancy With Normal And Deficient Vitamin D Levels: Intergrowth-21, World Health Organization Fetal Growth Curve, And Hadlock’s Estimated Fetal Weight ]]>
<![CDATA[Dewantiningrum, Julian]]>;
<![CDATA[Kristanto, Herman]]>;
<![CDATA[Pudjonarko, Dwi]]>;
<![CDATA[Mexitalia, Maria]]>;
<![CDATA[Ediati, Annastasia]]>;
<![CDATA[Soejoenoes, Ariawan]]>;
<![CDATA[Hadisaputro, Suharyo]]>
<![CDATA[ Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 2 (2023): Med Hosp ]]>
Publisher : <![CDATA[RSUP Dr. Kariadi ]]>
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DOI: 10.36408/mhjcm.v10i2.877
<![CDATA[Purpose : Analyze the cut-off point of fetal growth based on the Intergrowth-21, World Health Organization (WHO), and Hadlock’s estimated fetal weight (EFW) in pregnant women with normal or deficient vitamin D levels to predict neonatal outcomes. Method: This cross sectional study to develop a diagnostic test, included 120 of pregnant women who completed follow up until children aged 2 years, divided into normal and deficient vitamin D group. Ultrasound and maternal vitamin D level examined during the second trimester of pregnancy. EFW was calculated using Hadlock’s formula and plotted on the Intergrowth-21 and WHO curves. The reference standards were the neonatal outcome, LBW, stunting, and neurocognitive impairment. Significant odds ratio (OR) value and area under the curve (AUC) of 0.6 are used to determine the cut-off point to be used. Result: Fetal growth curve was based on the WHO at the 5th percentile to predict LBW to have an AUC of 0.6 and OR of 6, 95% confidence interval (CI) of 1.36–26.45. The AUC for predicting LBW based on Intergrowth and Hadlock were 0.45 and OR not significant. As well as the AUC estimated stunting based on Hadlock, the Intergrowth-21 and the WHO fetal growth curves is <0.6 with OR not statistically significant. The AUC predicted neurocognitive impairment based on WHO’s chart was 0.6 but OR not statistically significant. Conclusion: The WHO fetal growth curve can be used to predict LBW. The cut-off point of the fetal growth curve and which percentile is determined by the neonatal outcome.]]>
<![CDATA[Factors associated with pregnancy-related anxiety: a health facility-based study ]]>
<![CDATA[Wahyuni, Sri]]>;
<![CDATA[Pramono, Noor]]>;
<![CDATA[Hadisaputro, Suharyo]]>;
<![CDATA[Ediati, Annastasia]]>
<![CDATA[ International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024 ]]>
Publisher : <![CDATA[Intelektual Pustaka Media Utama ]]>
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DOI: 10.11591/ijphs.v13i3.24327
<![CDATA[Pregnancy is a critical phase for human beings, which can lead to various mental health issues, including anxiety. It is important to recognize that pregnancy-related anxiety can increase over time and should be addressed. This study aimed to explore the multifactor of pregnancy-related anxiety during the first trimester. A cross-sectional health facility-based study was conducted in four Semarang, Central Java, Indonesia public health centers. A total of 129 pregnant women were involved and identified some exposures, such as socio-demographics, nausea and vomiting during pregnancy (NVP), emotion regulation, social support, and anxiety levels. The average age of participants was 27.3 years. Their anxiety level was moderate to severe (37.2%), and 62.8% were identified as having mild anxiety. This study suggests that pregnant women who lack social support (AOR=4.105; 1.824-9.237) and emotion dysregulation (AOR=2.749; 1.244-6.075) were identified as the risk factors of maternal anxiety during the first trimester. Being employed (AOR=0.410; 0.182-0.922) protects the high anxiety during pregnancy. This study suggests that the lack of social support, including social interaction most influences pregnant women’s mental well-being. Therefore, it may be helpful to establish an intervention plan that strengthens social support to improve maternal mental well-being.]]>
<![CDATA[Moringa Leaf Nanoparticles as an Alternatives to Improve Hemoglobin and Hematocrit Levels in Stunting Toddlers ]]>
<![CDATA[Gustiya, Sherly Dwi]]>;
<![CDATA[Hadisaputro, Suharyo]]>;
<![CDATA[Sumarni, Sri]]>
<![CDATA[ Jurnal Kebidanan Vol 11, No 2 (2022): August 2022 ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/jk.11.2.2022.157-166
<![CDATA[Background: Stunting is a condition of short toddlers is a discrepancy between height for age which is measured based on the z-score <-2 SD. The highest prevalence of stunting in Central Java was in Magelang Districts by 37.6%. Aims: The objective of this study is to prove that consuming Moringa Oleifera leaf nanoparticles influences the increase in hemoglobin and hematocrit levels in stunting toddlers. Method: This is a quasy experimental study with pretest and posttest with control group design. The number of samples were 40 stunting toddlers who measured based on the z score <-2 SD. Those were divided into treatment groups (Moringa Oleifera leaf nanoparticles dose of 65 mg/day and supplementary feeding) and control groups (supplementary feeding) each group consisted from 20 toddlers. Interventions were given for 21 days. Examination of hemoglobin and hematocrit levels using the Hematology Analyzer method. Results: The hemoglobin level increased significantly from 11,365 g/dL to 12,610 g/dL with a value of p=0.001 in the intervention group. Moreover, hemoglobin level in the control group a slightly increased from 11.455 g/dL to 11.610 g/dL with a value of p=0.648. Hematocrit levels increased significantly (p=0.001) from 35.810% to 43.575% in the intervention group. Hematocrit level also improved slightly in the control group from 31.330% to 31.690%. However, it was not significantly with p=0.455. Conclusion: It is Proved that Moringa Oleifera leaf nanoparticles improves hemoglobin and hematocrit levels in stunting toddlers. The increase hemoglobin and hematocrit levels are greater in the intervention group rather than the control group.]]>
<![CDATA[Stres, Kecemasan dan Kadar Kortisol Serum Wanita dengan Sindrom Ovarium Polikistik (SOPK) ]]>
<![CDATA[Kurniawati, Erna Yovi]]>;
<![CDATA[Hadisaputro, Suharyo]]>;
<![CDATA[Suwandono, Agus]]>
<![CDATA[ JURNAL KESEHATAN REPRODUKSI Vol 10, No 3 (2023) ]]>
Publisher : <![CDATA[Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM ]]>
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DOI: 10.22146/jkr.72468
<![CDATA[Latar Belakang: SOPK dikaitkan dengan risiko kesehatan mental jangka panjang seperti disfungsi seksual, gangguan kesehatan, gangguan mood, kecemasan, dan depresi. Kadar kortisol mempengaruhi fungsi endokrin lain dalam tubuh dan dapat mempengaruhi resistensi insulin dan anovulasi.Tujuan: Mengetahui tingkat stress, tingkat kecemasan dan kadar kortisol serum wanita dengan sindrom ovarium polikistik (SOPK)Metode: Penelitian deskriptif, metode sampel pusposive sampling dengan jumlah responden 30 wanita dengan sindrom ovarium polikistik di Yogyakarta. Instrumentasi menggunakan Kuesioner State Anxiety dan Trait Anxiety (STAI), Perceived Stress Scale-10 (PSS-10), dan Kadar kortisol serum dengan ELISA di LPPT UGM.Hasil dan Pembahasan: Seluruh responden mengalami kecemasan, sebesar 53% responden mengalami kecemasan berat, dan seluruh responden mengalami tingkat stress berat. Rerata kadar kortisol serum 124.98 mcg/dl.Kesimpulan: Faktor psikologis sebagai indikator psikologis yang perlu dicegah atau dikelola saat merawat SOPK. Kombinasi terapi fisik dan psikoterapi atau mindfulness diperlukan untuk efektivitas terapi yang optimal.]]>
<![CDATA[In vivo study of the antihypertensive effect of bidara leaf (Ziziphus spina-christi) during pregnancy ]]>
<![CDATA[Dilla, Tasya Nurlaila]]>;
<![CDATA[Hadisaputro, Suharyo]]>;
<![CDATA[Santjaka, Aris]]>
<![CDATA[ MEDISAINS Vol 19, No 2 (2021) ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Purwokerto ]]>
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DOI: 10.30595/medisains.v19i2.11431
<![CDATA[Background: Bidara is drought tolerant and very easy to grow in tropical climates such as Indonesia. Bidara contains a combination of calcium, potassium, and magnesium, and active flavonoid compounds, and antioxidant activity that play a role in inhibiting free radical damage, improving endothelial function so that it can potentially lower blood pressure. Previous studies explained that a dose variant of no more than 300mg/kg BW is beneficial while minimizing pathological changes. However, there has been no research related to the effect of bidara leaf in lowering blood pressure, so it is necessary to do related research.Objective: Analyze the effect of bidara leaf extract at a 200 mg/kg BW dose and 300 mg/kg BW on systolic and diastolic blood pressure.Methods: 24 pregnant female Wistar rats induced hypertension, aged 6-8 weeks with a weight of 130-230 grams. The rats were randomized so that they consisted of 2 control groups and two experimental groups, which were given various doses of bidara leaf for nine days. Blood pressure was measured using non-invasive CODA.Results: The blood pressure of rats in the bidara leaf extract group at doses of 200mg/kg BW and 300mg/kg BW decreased systolic and diastolic compared to the control group (p<0.05). The 200mg/kg BW dose group experienced a decrease in blood pressure of 12.3% for systolic and 16.32% for diastolic; the 300mg/kg BW dose group experienced a decrease in blood pressure of 19.99% for systolic and 27.73% for diastolic.Conclusion: Bidara leaf extract can reduce the blood pressure of pregnant rats with hypertension.]]>
<![CDATA[Effect of pomegranate extract (Punica granatum L.) on blood pressure and nitric oxide in gestational hypertension ]]>
<![CDATA[Salsabila, Farah]]>;
<![CDATA[Hadisaputro, Suharyo]]>;
<![CDATA[Sunarjo, Lanny]]>
<![CDATA[ MEDISAINS Vol 21, No 2 (2023) ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Purwokerto ]]>
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DOI: 10.30595/medisains.v21i2.17484
<![CDATA[Background: As a complication of pregnancy, uncontrolled hypertension will continue to be a complication that harms both mother and baby. Pomegranate peel, which contains high antioxidants, is potentially used as an antihypertensive of adjuvant pharmacological therapy. However, there has been no research on the effect of pomegranate extract in lowering blood pressure, so it is necessary to do related research.Purpose: Analyze the effect of pomegranate peel extract on blood pressure and nitric oxide levels in gestational hypertension.Methods: This is a quasi-experiment design pre-post-test with the control group. Through purposive sampling techniques, 32 respondents were divided into two groups. During 14 days, the intervention group received nifedipine 10 mg/day with 500 mg of pomegranate peel extract, while another group was only given nifedipine 10 mg/day.Results: The blood pressure of the intervention group decreased compared to the control group (p<0.05). Meanwhile, the nitric oxide level of the intervention group is increased compared to the control group (p<0.05).Conclusions: Pomegranate peel extract can reduce blood pressure and enhance nitric oxide levels in gestational hypertension.]]>
<![CDATA[Calcium supplementation from chicken eggshells to increase nitric oxide levels and control blood pressure in gestational hypertension ]]>
<![CDATA[Rahmah, Aulia Agyanti]]>;
<![CDATA[Hadisaputro, Suharyo]]>;
<![CDATA[Ambarwati, Eny Retna]]>
<![CDATA[ MEDISAINS Vol 20, No 1 (2022) ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Purwokerto ]]>
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DOI: 10.30595/medisains.v20i1.13378
<![CDATA[Background: Hypertension is one of the highest causes of death in pregnant women. Calcium deficiency can lead to hypertension. Chicken eggshell can be used as a natural calcium supplementation therapy in hypertension.Purpose: Analyze the effect of chicken eggshell on blood pressure through the increased nitric oxide level in gestational hypertension.Methods: This is Quasy experiment research with pretest and posttest with control group design. Respondents were ≥20 weeks pregnant women with gestational hypertension. Determination of respondents by purposive sampling obtained experimental group (n=12) and control group (n=12). 1.1 g/day of eggshell flour was given for 14 days.Result: Mean of systolic and diastolic blood pressure in experimental group decreased 14.25 mmHg or 9.5% (p=0.000) and 12.84 mmHg or 13.04% (p=0.000) after received chicken eggshell flour for 14 days compared to control group mean of systolic and diastolic blood pressure increased 1.92 mmHg or 1.35% (p=0.000) and 0.33 mmHg or 0,34% (p=0.121). Nitrit oxide level of experimental group increased 8.250 μmol/L or 20.93% (p=0.020) and control group decreased 3.083 μmol/L or 7.20% (p=0.488).Conclusion: Chicken eggshell flour affects increasing nitric oxide levels and controls systolic and diastolic blood pressure in gestational hypertension.]]>
<![CDATA[The effect of warm water foot bath therapy on the blood pressure and cortisol levels in gestational hypertension ]]>
<![CDATA[Amin, Dewita Rahmatul]]>;
<![CDATA[Hadisaputro, Suharyo]]>;
<![CDATA[Isnawati, Muflihah]]>
<![CDATA[ MEDISAINS Vol 20, No 3 (2022) ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Purwokerto ]]>
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DOI: 10.30595/medisains.v20i3.14899
<![CDATA[Background: Pregnant women are susceptible to anxiety disorders that result in hypertension. Previous studies that have been carried out with warm water foot bath therapy, which can relax the body, previous research only measured the level of anxiety psychologically and never seen a physiological/molecular increase in blood pressure from the indicator of cortisol levels.Purpose: To analyze the effect of warm footbath therapy on the blood pressure and cortisol levels in gestational hypertension.Methods: This experimental study has a randomized pre-post-test control group design. They involved 40 subjects in two groups. The control group was given 10 mg of nifedipine, while the intervention group was given 10 mg of nifedipine and a warm water foot bath at 40-43oC for 15 minutes for 14 consecutive days. Pre-post cortisol levels were measured with the ELISA method cortisol test.Results: A warm water foot bath therapy effectively decreased systolic blood pressure in the intervention group, which was 43 mm Hg compared to the control group, 19 mm Hg (p<0.05). Diastolic blood pressure in the intervention group was 15.5 mmHg compared to the control group's 6.5 mmHg (p<0.05), and cortisol levels in the intervention group: 48.1 ng/ml compared to the control 14.5 ng/ml (p<0.05).Conclusion: Warm water foot bath therapy at 40-43oC for 15 minutes for 14 consecutive days reduces systolic blood pressure by decreasing cortisol levels in hypertensive pregnant women.]]>
