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All Journal Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Zuriat Niagawan JURNAL AGROTEKNOLOGI Jurnal Teknologi Informasi dan Ilmu Komputer ODONTO Dental Journal Jurnal Agro Jurnal Ilmu Produksi dan Teknologi Hasil Peternakan Kultivasi Indonesian Journal of Learning and Instruction JUTIS : Jurnal Teknik Informatika Jurnal Pustaka Mitra : Pusat Akses Kajian Mengabdi Terhadap Masyarakat Cakrawala Bahasa Odonto dental journal Jurnal Bilingual Jurnal Kajian Budaya dan Humaniora (JKBH) Kabuyutan: Jurnal Kajian Iilmu Sosial dan Humaniora Berbasis Kearifan Lokal
Ade Ismail
Deparments of Paediatrics and Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan.
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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Journal : ODONTO Dental Journal

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Antibacterial Effectivity of Nanoemulgel Phaleria macrocarpa’s leaf on the Porphyromonas gingivalis ATCC 33277 Biofilm Thickness Pratiwi, Rosa; Ratnawati, Irma Dewi; Ismail, Ade; Nurhapsari, Arlina; Amelia, Rosalita
Odonto : Dental Journal Vol 11, No 1 (2024): July 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.1.168-174

Abstract

Porphyromonas gingivalis is an oppoturnistic microorganism in periodontal disease that is formed at the stage maturation of biofilm formation. One of the natural materials biofilm reduction is the Phaleria macrocarpa. Phaleria macrocarpa’s leaf contains chemical compounds such as flavonoids, tannins, alkaloids, saponins that function as antibacterials.The aim of this research is to determine the effectiveness of the nanoemulsion of the gel Phaleria macrocarpa’s leaf  on the thickness of the P. gingivalis bacterial biofilm. The research design was carried out with a post test only with a total of 28 samples, then divided into 4 groups of treatment of Phaleria macrocarpa’s leaf extract nanoemulsion gel preparations with variations in concentrations of 30%, 40%, and 50%, as well as a control group of 25% metronidazole gel. The reading of the anti-biofilm thickness test results was measured by OD (Optical density) using an ELISA-reader. One way Anova parametric test among obtained p<0.000 results showing the effect of Phaleria macrocarpa’ leaf gel nanoemulsion extract on the decrease in the thickness of the Porphyromonas gingivalis bacterial biofilm. It can be concluded that the nanoemulsion gel formulation of Phaleria macrocarpa’s leaf extract concentrations of 30%, 40%, and 50% is effective, with a concentration 50% was most effective against reducing the thickness of the bacterial biofilm Porphyromonas gingivalis.
Co-Authors A. Hidayat Abdulrahman, Yuli Yanti Aep Wawan Irwan Agung Karuniawan Agus Wahyudin Al Hadid Firdaus, Vipkas Amelia, Rosalita Anggraeni, Tiffani Dias ANNE NURAINI ANNE NURBAITY Anwar Ismail, Anwar Anwar, Indry Widyasti Arlina Nurhapsari Badrun, Fitriana Bari, Ichsan Nurul Bella Dian Ratnasari., Bella Dian Citra Bakti, Citra D Ustari, D D. Arief, D. D. Ruswandi, D. D. Veronika, D. Debby Ustari Dedi Ruswandi Elok Nur Hamdana Erni Suminar F. Kasim, F. Fadhilah, Rifat Farid Angga Pribadi, Farid Angga Farida Damayanti Firmansyah Firmansyah Fitri, Aida Furqon, Agung Hesya Hasibuan, John Hendra Parlindungan Hijril Ismail, Hijril I. N. Hafhittry, I. N. Ika Yuliasari Indrajati, Septian Intan Ratna Dewi Anjarsari Irsyad Arif Mashudi Khalisha, Ana Kusumah, Fajar Maulana Wijaya Laela, Ela M. Rachmadi, M. Maulana , Haris Maulana, Haris Meddy Rachmadi N. Wicaksana, N. Neni Rostini Noladhi Wicaksana Novanda Sari, Dwi Nugraha, Shandy Odim, Cecep Pangestika, Kintan Widya Pramudhita, Agung Nugroho Pratiwi, Vika Faraditha Ratnawati, Irma Dewi Rija Sudirja Rosa Pratiwi, Rosa Rudianto, Damayanti Rudianto, Safira Damayanti Sailuddin, Sartika Putri Santi Rosniawaty Saprudin, Alviera Zulfiana Shabrina, Rahmaini Afifah Sintanawati, Yuli Siswanto, Shantosa Yudha Sitanawati, Yuli Sukmayadi, K. Syihab, Fakhri Nasharul T. K. Putri, T. K. WARID ALI QOSIM Wawan Sutari WICAKSONO, ARIF AFFAN Widya Andini, Amelia Wijaya Kusumah, Fajar Maulana Yamin, Desiratnawati Yani Maharani, Yani Yetty Yetty Yudithia Maxiselly, Yudithia Yuyun Yuwariah Z. Daulati, Z.