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Isolation and Characterization of Ethyl Acetate Fraction from Abroma augusta L as an Anti-Inflammatory Agent Latief, Madyawati; Tarigan, Indra Lasmana; Muhaimin, Muhaimin; Amanda, Hilda; Yulianti, Nike Desvi
Makara Journal of Science Vol. 25, No. 2
Publisher : UI Scholars Hub

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Abstract

Abroma augusta is a bush plant that lives on the edge of the river. This plant is commonly used as an anti-inflammatory drug for joints and broken bones. It contains several secondary metabolites, such as alkaloids, triterpenoids, steroids, and flavonoids, which exhibit anti-inflammatory activity. UV-visible (UV-Vis) spectrophotometry of isolate 1.3 indicated absorption at a maximum wavelength of 282 nm. The wavelength suggested that the electron transition π–π* is the absorption of UV spectra typical for triterpenoid compounds that have chromophores in the form of non-conjugated double bonds. FT-IR spectrophotometer characterization data from isolate 1.3 revealed the presence of triterpenoid compounds having carboxyl groups C-O (ester), C-(CH3)2 (gem-dimethyl), carbonyl C = O esters, and C-H (alkyl). Analyses of UV-Vis, FT-IR, GC-MS, 1H-NMR, and 13C-NMR spectra showed that the compound obtained was the triterpenoid β-amyrin. Activity test demonstrated that isolate 1.3 with a 10 mg dose showed stronger anti-inflammatory activity than the positive control of sodium diclofenac.
ANTI INFLAMMATORY ACTIVITY OF SUNGKAI LEAVES (Peronema canescens JACK) ETHANOL EXTRACT IN CARRAGEENAN INDUCED MICE Madyawati Latief; Anggun Tri Fisesa; Putri Maya Sari; Indra Lasmana Tarigan
Jurnal Farmasi Sains dan Praktis Vol 7 No 2 (2021)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v7i2.4532

Abstract

Anti-inflammatory compounds play a role by inhibiting the formation of prostaglandin mediators, inhibiting the migration of leukocytes to the area of ​​inflammation, and inhibiting the release of prostaglandins from the cells where they are located. Several plant-derived compounds that can act as anti-inflammatory candidates are flavonoids, saponins, alkaloids, and phenols. This study aims to determine the anti-inflammatory activity of the ethanol extract of Sungkai leaves and to determine the effect of the concentration given on the level of anti-inflammatory activity. The method used was the formation of granuloma pockets and edema on the mice's backs by inducing subcutaneous carrageenan using ethanol extract of Sungkai leaves with various concentrations of 5%, 10%, and 15%, respectively. The results of anti-inflammatory activity showed that the ethanol extract of Sungkai leaves had a significant effect on the average exudate volume and the percentage of inflammation inhibition. At a concentration of 15%, the extract was able to reduce the volume of exudate by 46,67 ± 5,506 µl and inhibition of inflammation by 87.78%. In addition, the ethanol extract of Sungkai leaves significantly affected lymphocytes, stem neutrophils, and segment neutrophils, but did not significantly affect the number of monocyte cells. At a concentration of 15%, the ethanol extract of Sungkai leaves showed the smallest number of leukocyte cell types, namely 50.11 ± 2.389 lymphocyte cells; stem neutrophil cells 10,44 ± 0,475; segmented neutrophil cells were 19.78 ± 0.596 and monocyte cells 2,0 ± 0,236. It can be concluded that the ethanol extract of Sungkai leaves has anti-inflammatory activity but has not approached the effect of anti-inflammatory drugs in general.
Diseminasi Teknologi Sambung Pucuk Tanaman Kopi Liberika di Desa Jati Mulyo Dendang Kabupaten Tanjung Jabung Timur Elis Kartika; Lizawati Lizawati; Fitry Tafzi; Yusnaidar Yusnaidar; Addion Nizori; Sutrisno Sutrisno; Indra Lasmana Tarigan; Ratih Dyah Puspitasari; Madyawati Latief
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 4, No 3 (2022)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v4i3.6090

Abstract

Desa Jati Mulyo menjadi salah satu desa yang pertumbuhan lahan kopi Liberika cukup tinggi, melalui bantuan bibit dari Dinas Perkebunan masyarakat mulai beralih dan fokus pada Kopi. Produksi bibit kopi serta upaya membentuk sentra produksi bibit kopi diperlukan penguatan pada penangkar bibit, sehingga dengan adanya penangkar bibit tersertifikasi dapat dihasilkan bibit kopi yang unggul dan bermutu tinggi. Teknologi sambung pucuk secara umumnya dilakukan pada tanaman kopi Liberika ini bertujuan untuk memperoleh tanaman anakan (baru) dengan karakteristik kualitas tanaman dan buahnya identik dengan induknya, yang diperoleh dari tanaman unggul. Kegiatan PKM bertujuan untuk mendiseminasikan teknologi sambung pucuk pada masyarakat Petani Kopi di Desa Jati Mulyo agar keunggulan kopi Liberika dapat dipertahankan. Kegiatan ini dilaksanakan pada Oktober Tahun 2021. Metode dalam pelaksanaan kegiatan pengabdian ini meliputi pembelajaran masyarakat melalui kegiatan penyuluhan, sharing dan diskusi, demonstrasi serta praktik langsung. Hasil kegiatan menunjukkan bahwa diseminasi teknologi sambung pucuk dirasakan petani sangat bermanfaat dan sangat dibutuhkan. Melalui kegiatan pengabdian kepada masyarakat ini terjadi peningkatan pengetahuan masyarakat petani dalam melalukan grafting, masyarakat sangat antusias dalam mengikuti kegiatan pelatihan. Melalui kegiatan ini juga petani berharap dapat berkesinambungan guna menghasilkan bibit kopi Liberika yang berkualitas. Kegiatan diseminasi ini mendorong masyarakat untuk semakin fokus mengembangkan kopi Liberika dengan kekhasan wilayah gambut. Jati Mulyo village is one of the villages where the growth of Liberica coffee land is quite high, through the assistance of seeds from the Plantation Service, the community began to shift and focus on coffee. Coffee seed production and efforts to establish coffee seed production centers require strengthening of seed breeders, so that with the existence of certified seed breeders, superior and high quality coffee seeds can be produced. The Top grafting technology is generally carried out on Liberica coffee plants with the aim of obtaining (new) saplings with identical plant and fruit quality characteristics to the parent, obtained from superior plants. This activity aims to disseminate top grafting technology to the coffee farmer community in Jati Mulyo Village so that the superiority of Liberica coffee can be maintained. This activity was carried out in October 2021. The method of implementing this activity includes community learning through counseling activities, sharing and discussions, demonstrations and hands-on practice. The results of the activity show that the dissemination of shoot grafting technology is felt by farmers to be very useful and very much needed. Through this community service activity, there is an increase in the knowledge of the farming community in doing grafting, the community is very enthusiastic in participating in training activities. Through this activity, farmers also hope to be sustainable in producing quality Liberica coffee seeds. This dissemination activity encourages the community to focus more on developing Liberika coffee with the uniqueness of the peat area.
UJI IRITASI DAN EFEKTIFITAS SPRAY HANDSINITIZER EKSTRAK ETANOL DAUN JERUJU (Achantus Ilicifolious) SEBAGAI ANTIBAKTERI Lestari, Uce; Suci, Ulan; Latief, Madyawati
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 1 (2021): Special Issues: JAMHESIC 2020
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (197.387 KB) | DOI: 10.22437/jmj.v9i0001.12891

Abstract

ABSTRAKPendahuluan: Acanthus ilicifolius.L merupakan tanaman mangrove yang banyak dimanfaatkan sebagaitanaman obat. Kandungan flavonoid dan fenolik yang terkandung didalamnya dapat digunakan sebagaiantibakteri. Setiap hari tangan kita menyentuh barang yang penuh dengan bakteri, salah satunya Staphylococcusaureus yang dapat mengakibatkan terjadinya infeksi kulit. Untuk mencegah penyebaran bakteri tersebut makadibuatlah spray hand sanitizer ekstrak etanol daun jeruju dengan konsentrasi 6%.Metode: Penelitian ini bertujuan untuk memformulasi sediaan farmasi yang memiliki aktivitas daya hambatterhadap bakteri penyebab infeksi kulit. Spray Hand sanitizer ini dipilih karena lebih praktis, tidak lengket dancepat menyebar pada kulit. Tahapan penelitian terdiri dari uji iritasi, hedonik dan aktivitas antibakteri terhadapStaphylococcus aureus sebelum dan sesudah penggunaan spray hand sanitizer. Menggunakan 10 orangpanellist rentang usia 25 s/d 30 tahun kategori kulit tangan normal.Hasil: Hasil menyatakan bahwa tidak ada satupun panellist yang mengalami iritasi, gatal, bengkak ataupunkemerahan pada kulit, 80% menyukai warna, aroma dan bau dari spray hand sanitizer, nilai daya hambatminimum terhadap bakteri Staphylococcus aureus sebesar 5,66 mm dan jumlah koloni sebelum penggunakansebanyak 88 koloni sedangkan setelah penggunaan sebanyak 10 koloni.Kesimpulan: Dapat disimpulkan bahwa spray hand sanitizer ekstrak etanol daun jeruju 6% aman padapenggunaannya serta memiliki kemampuan untuk menghambat bakteri Staphylococcus aureus penyebab infeksikulit.Kata kunci: Jeruju, spray handsinitizer, Staphylococcus Aureus
Antidiabetic Activity of the Methanol Fraction of Sungkai Leaves (Peronema canescens Jack) Indra Lasmana Tarigan; Anggi Ayunda Triani; Madyawati Latief
The Journal of Pure and Applied Chemistry Research Vol 12, No 2 (2023): May-August 2023
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jpacr.2023.012.02.699

Abstract

Diabetes Mellitus (DM) is one of a group of metabolic diseases characterized by hyperglycemia caused by a disturbance in insulin so that blood glucose levels increase. Prevention of absorption of blood glucose by the intestine can be done with the help of the enzyme α-glucosidase. Based on the results of phytochemical tests, it is known that the methanol fraction of sungkai leaves contains flavonoid compounds. The Fourier Transform Infra-Red (FTIR) spectrum showed that the isolates had phenolic O-H groups (3,354.53 cm-1, 1,359.28 cm-1), aromatic C=C group (1,615.48 cm-1), C-O-C ether group (1,046.60 cm-1) and aromatic C-H group (822.21 cm-1). In vivo antidiabetic activity test was carried out using test animals of white male mice which were induced by alloxan. Antidiabetic testing was carried out using 6 treatment groups with glibenclamide, Na-Carboxymethyl cellulose (Na-CMC) 0.5%, dose 175 mg/kgBW, 350 mg/kgBW, 700 mg/kg Body Weight (BW) and isolates 2 mg/kgBW. The results showed that the methanol fraction of sungkai leaves had the best antidiabetic activity at a dose of isolate and 700 mg/kgBW which was able to reduce blood glucose levels by 42.20% and 42.00%. In vitro antidiabetic testing through α-glucosidase enzyme inhibition mechanism did not show any antidiabetic activity at concentrations of fractions 5, 10, 25, 50 and 100 ppm.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK N-HEKSAN, ETIL ASETAT, DAN ETANOL DAUN DURIAN (Durio zibethinus Linn.) TERHADAP BAKTERI Propionibacterium acnes dan Staphylococcus epidermidis Shindi Amanda Rizki; Madyawati Latief; Fitrianingsih Fitrianingsih; Havizur Rahman
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 10 No. 3 (2022): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.275 KB)

Abstract

The durian plant is believed to have medicinal properties and has a distinctive name in each region, such as durian selat from Selat Village in Jambi. Parts of the durian plant such as durian skin and durian seeds have been shown to have antibacterial activity. This study aimed to determine the antibacterial activity and the diameter of the inhibition zone of strait durian leaves (Durio zibethinus Linn.) against Propionibacterium acnes and Staphylococcus epidermidis bacteria. Antibacterial activity testing was carried out using the disc diffusion method. Based on the results obtained, n-hexane, ethyl acetate, and ethanol extract of durian leaves have antibacterial activity at 1% to 6% concentration with weak level against Propionibacterium acnes bacteria and moderate level against Staphylococcus epidermidis bacteria. The highest inhibition zone diameter was obtained from ethyl acetate extract 4.76 mm (weak category) against P. acnes bacteria and the highest inhibition zone diameter was obtained from ethyl acetate extract 6.26 mm (medium category) against S. epidermidis bacteria with MIC values ​​(Minimum Inhibitory Concentration) at 1% concentration.
Senyawa Turunan Terpenoid dari Ekstrak Aseton Daun Perepat (Sonneratia alba) dan Aktivitasnya Terhadap Escherichia coli Muhaimin Muhaimin; Kurnia Nastira Ningsih; Madyawati Latief
Journal of The Indonesian Society of Integrated Chemistry Vol. 13 No. 2 (2021): Journal of The Indonesian Society of Integrated Chemistry
Publisher : Pendidikan Kimia FKIP Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jisic.v13i2.14714

Abstract

Perepat (Sonneratia alba) secara tradisional masih digunakan untuk pengobatan luka, diare dan demam. Diare disebabkan oleh Escherichia coli. Daun perepat mengandung alkaloid, fenolat, triterpenoid, flavonoid, tanin, saponin, steroid dan glikosida. Terpenoid berpotensi sebagai antibakteri. Penelitian ini bertujuan untuk isolasi senyawa turunan terpenoid dan uji aktivitasnya terhadap Escherichia coli. Proses isolasi dilakukan dalam 3 tahap yaitu kromatografi vakum cair, kromatografi kolom gravitasi pertama dan kromatografi kolom gravitasi kedua. Isolat F2.2.2 murni sebagai kristal putih tajam. Titik leleh isolat F2.2.2 pada 210,2-211,1 °C. Hasil spektrofotometer UV-Vis memiliki serapan maksimum pada 203 nm dan 212 nm yang menunjukkan adanya transisi elektron π→π* yang menunjukkan adanya gugus kromofor yang khas pada sistem ikatan rangkap C=C terisolasi. Hasil interpretasi data FTIR menunjukkan senyawa memiliki gugus -OH (3277,20 cm-1), -C-O (1047,39 cm-1), -C=C terisolasi (1656,92 cm-1), -C-H alifatik (2896,24 cm-1) dan gem dimetil (1463,07 cm-1 dan 1377,23 cm-1) sebagai karakteristik senyawa triterpenoid. Berdasarkan hal tersebut diduga isolat F2.2.2 merupakan senyawa turunan triterpenoid lupan yaitu Lupeol. Hasil uji aktivitas antibakteri terhadap Escherichia coli menunjukkan bahwa ekstrak aseton daun perepat memiliki aktivitas yang lemah, sedangkan isolat F2.2.2 tidak memiliki aktivitas.
Isolasi Senyawa Turunan Kuinon dari Ekstrak Aseton Daun Perepat (Sonneratia Alba) dan Uji Aktivitas Terhadap Staphylococcus Aureus Muhaimin Muhaimin; Dwi Wahyu Ramadhan; Madyawati Latief
Journal of The Indonesian Society of Integrated Chemistry Vol. 14 No. 1 (2022): Journal of The Indonesian Society of Integrated Chemistry
Publisher : Pendidikan Kimia FKIP Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jisic.v14i1.18213

Abstract

[Isolation of Quinone Derivative Compound from Acetone Extract of Perepat Leaves (Sonneratia alba) and Activity Testing Against Staphylococcus aureus] Staphylococcus aureus merupakan salah satu patogen paling umum yang menyebabkan infeksi nosokomial. Kemudian dengan cepatnya perkembangan resistensi yang ditunjukkan S. Aureus terhadap antibiotik yang ada, maka pengembangan terus dilakukan baik secara sintesis maupun dari bahan alam. Berdasarkan beberapa penelitian terdahulu S. Alba memiliki aktivitas antimikroba yang baik dari beberapa bagian tumbuhannya. Penelitian ini bertujuan untuk isolasi senyawa dari ekstrak aseton daun S. alba dan pengujian aktivitasnya terhadap pertumbuhan bakteri S. aureus. Tahapan yang dilakukan dalam penelitian ini meliputi skrining fitokimia, isolasi senyawa dengan menggunakan kromatografi vakum dan kromatografi grafitasi dan karakterisasi dengan spektrofotometri UV-vis dan FTIR serta uji antibakteri dengan metode difusi kertas cakram. Hasil isolasi diperoleh isolat F.5.2 menunjukkan hasil positif pada uji kuinon dan triterpenoid. Berdasarkan karakterisasi spektrofotometri UV-Vis diperoleh pita serapan maksimum pada 257 nm dan 301,2 nm yang menandakan gugus kromofor C=O terkonjukasi dan berdasarkan spektrum FTIR diperoleh beberapa serapan pada bilangan gelombang 3264,57 cm-1 (ulur O-H), 2921,06 cm-1 (C-H alifatik), 1692,80 cm-1 (C=O), 1611,28 cm-1 (ulur C=C) dan 1315,93 cm-1 (C-O). Berdasarkan uji antibakteri terhadap S. aureus oleh ekstrak aseton daun S. Alba dan isolat F.5.2 menunjukkan adanya aktivitas penghambatan pertumbuhan bakteri S. aureus
X-Ray Fluorescence Monitoring Metal Content and Nutrient Elements for Predicting Soil Fertility Parameters Based on pH in Ultisol Soil Samsidar, Samsidar; Maison, Maison; Ermadani, Ermadani; Latief, Madyawati; Pebralia, Jesi; Riany, Hesti; Amanda, Dwi Rahma; Maulana, Lucky Zaehir
International Journal of Hydrological and Environmental for Sustainability Vol. 2 No. 3 (2023): International Journal of Hydrological and Environmental for Sustainability
Publisher : CV FOUNDAE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58524/ijhes.v2i3.290

Abstract

Soil fertility parameters, including macronutrients, micronutrients, and metal content, are very important for optimizing agricultural and plantation land management. Ultisol is a type of soil that is commonly used as a planting medium for oil palm plantations, rubber, and various types of vegetables. Continuous land use causes variations in nutrient and metal content. This change is also caused by the fertilization process and the characteristics of the plants grown in the area. In this study, an analysis of soil fertility parameters (macronutrients, micronutrients, and metal content) was analyzed using X-Ray Fluorescence (XRF) on Ultisol soil taken from Muara Jambi Regency, Indonesia. This analysis was conducted across land-use areas (Palm, Rubber, Vegetables, and Forest). Subsequently, the obtained measurements were used to model correlations with soil pH values to predict soil fertility parameters. The quantitative results showed that the metal content values were reasonably consistent across all locations regarding metal types and their percentage concentrations. However, locations 1 (T1) and 2 (T2) have higher aluminum (Al) content than locations 3 and 4 and lower magnesium (Mg) content. The modeling, when correlated with pH values, indicated that metal elements correlated 0.938, macronutrients 0.934, and micronutrients 0.767. From these correlations, it can be qualitatively inferred that there is a strong relationship between pH and the presence of metal content, macronutrients, and micronutrients. In the future, this can serve as a model for estimating the presence of soil fertility parameters.
Encapsulation of Jeruju Leaves Ethanol Extract (Acanthus ilicifolius L.) and It's Antiinflammatory Activities Against Carrageenan-Induced Mice Tarigan, Indra Lasmana; Kharisma, Tiara; Bemis, Restina; Sutrisno, Sutrisno; Latief, Madyawati
Molekul Vol 18 No 3 (2023)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2023.18.3.8820

Abstract

Jeruju (Acanthus ilicifolius) leaves ethanol extract contains flavonoids that function as an antiinflammatory source. So it is necessary to research to increase the utilization of ethanol extract of Acanthus ilicifolius leaves (A. ilicifolius L.) in encapsulations to increase the stability of antiinflammatory chemical compounds. Concentrated dyestuff extracts are often unstable, so they need to be converted into solid form, and one technique that can be done is encapsulation. Encapsulation aims to protect sensitive components of the material and reduce the degradation of active compounds in the material. The research method begins with preparing samples to be extracted with ethanol solvent, extract phytochemical screening tests, validation determination tests for the analysis method of ethanol extract levels of jeruju leaves, encapsulated formulations, encapsulated physics and chemical properties test and anti-inflammatory tests. In this research, the secondary metabolite compounds contained in the ethanol extract of Jeruju Leaves were flavonoids, phenolics, steroids, and saponins. The determination of the validation of the analysis method of ethanol extract levels of jeruju leaves was obtained by measurement using a UV-vis spectrophotometer and obtained extract levels of 1367,831 mg/g. This research used maltodextrin coating material for encapsulation formulation because it has low viscosity in many ratios, high solubility, has no taste. The freeze-dryer method was used in this study because it produces better drying quality than other drying methods. The physical property test was carried out by analysis using FTIR and SEM while the chemical properties of encapsulation obtained the highest yield proportion of 58.81%, and the highest solubility proportion of 98.76%. Anti-inflammatory testing is carried out using male mice as test animals. Anti-inflammatory testing in mice based on the Rat hind paw oedema method. The average percent inhibition of each dose administered is calculated based on the data results. The high average percent inhibition obtained for Diclofenac Na is 80%. In the research Encapsule 1:12, the 120 mg/KgBW dose had a significant percentage of inhibition of 75.55%, with Na Diclofenac dose of 10 mg/KgBW being 80%.
Co-Authors -, Maison Addion Nizori Ahmad Fadhil Alfi Khatib, Alfi Alrizal, Alrizal Amanda, Dwi Rahma Amanda, Hilda Anggi Ayunda Triani Anggun Tri Fisesa Ardhica, Jammes Arum, Dewi Azizah, Regina Wan Batubara, Ummi Mardhiah Bela, Anisa Betharia Juli Mas Tambunan Br Sembiring, Vera Lorensya Budiyanto Budiyanto Budiyati Ichwan Bulan, Catherine Putri Delviani, Delviani Dewi, Tribuana Tungga Dwi Wahyu Ramadhan Dyah Puspitasari, Ratih Elis Kartika Ermadani Ermadani Faizar Farid Farah, Farah Fauzan Azima Fikriansyah, Muhammad Fiolita Etsa Aurora Fisesa, Anggun Tri Fitrianingsih Fitrianingsih FITRY TAFZI Havizur Rahman Helmina Mandalahi Helmina Mandalahi, Helmina Hengky Irawan, Hengky Heriyanti Heriyanti Heriyanti Heriyanti, Heriyanti Humaryanto, Humaryanto Husna, Naimul Ihsan, Mahya Ilmavia Wilantika Indra Lasmana Tarigan Jamaludin Al-Anshori Kharisma, Tiara Kurnia Nastira Ningsih Lenny Marlinda Lince Muis Lince Muis Lizawati Lizawati Lucky Zaehir Maulana Maharani, Rizky Maharani, Viola Giary Rizkillah Masruri Masruri Melani, Fitria Muhaimin Muhaimin Muhaimin Muhaimin Mursyid Djawas Nabila, Annisa Candra Nadia Rahmasari Natasya, Dian Nelson Nelson Nelson Nindita Clourisa Amaris Susanto Nurjannah, Sofia Nurul Huda Oktavioni, Marsella Pebralia, Jesi Prabawa, Satria Prahandika, Graha Puspitasari, Ratih Dyah Putri Maya Sari Putri Maya Sari Putri Maya Sari Putri, Silvi Ayudiah Putri, Yunika Eka qurrota aini Rahayu Sindy Ramadhan, Ilham Ifandi Ratih Dyah Puspitasari Razai, Tengku Said Resta, Ichy Lucya Restina Bemis Restina Bemis, Restina Riany, Hesti Rizki Ananda Rosi Rahayu Saharin, Siti Munirah Samsidar Samsidar Saputra, Muhammad Furqon Novryan Sarah Aknesia Marbun Sari, Tika Seow, Eng Keng Shadrina, Putri Nur Shindi Amanda Rizki Sholeha Annisa Martines Silaban, Desy Vania Silvi Leila Rahmi Sinurat, Julius Alvin Novensius Suci, Ulan Susanto, Nindita Clourisa Amaris Sutrisno Sutrisno, Sustrisno Sutrisno, Sutrisno Tarigan, Indra L. Uce Lestari Vitadella, Veronika Warni, Tri Wazzan, Huda Winda Dwi Setiawati Wulan Safitri, Wulan Yana Cahyana Yoza Fendriani Yulianti, Nike Desvi Yusnaidar Yusnaidar Yusnaidar, Yusnaidar Yusof, Yus Aniza Zulnita, Anis