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Journal : Medula

LITERATUR REVIEW: TRIKIASIS Gerliandi, Egi Oktarian; Mustofa, Syazili; Lisiswanti, Rika; Sukohar, Asep
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.1008

Abstract

Trichiasis is a pathological disorder characterized by the abnormal growth of eyelashes towards the eyeball, resulting in irritation, pain, and potential harm to the eye. This research utilizes a method of sear Trichiasis is a pathological disorder characterized by the abnormal growth of eyelashes towards the eyeball, resulting in irritation, pain, and potential harm to the eye. The pathophysiology of trichiasis originates with alterations in the structure of the eyelashes and eyelids. Trichiasis is classified into six categories according to the source and location of abnormal eyelash development. The clinical presentation of trichiasis differs according on the extent of the condition. Trichiasis can be diagnosed by assessing the patient's medical history and doing a thorough physical examination. The history encompasses the patient's medical background, record of medication usage, past eye surgical procedures, and the patient's reported symptoms. The physical examination encompasses assessments of visual acuity, biomicroscopic inspection, evaluation of eyelid margins, and the administration of the Schirmer test. The treatment for trichiasis is determined by the extent of eyelash involvement, which includes factors such as the Soft Contact Lense Base Curve. Treatment options may include eyelash removal and surgical procedures, depending on the specific form of trichiasis that the patient is suffering. ching for articles on Google Scholar, PubMed, and NCBI. The search is limited to a specific year range determined by the researcher. The search is conducted using keywords such as trichiasis, etiology of trichiasis, pathophysiology of trichiasis, classification of trichiasis, clinical manifestations of trichiasis, diagnosis of trichiasis, and management of trichiasis. The study's findings revealed that the cause of trichiasis remained unknown, however it was hypothesized to be a result of infection. The pathophysiology of trichiasis originates with alterations in the structure of the eyelashes and eyelids. Trichiasis is classified into six categories according to the source and location of abnormal eyelash development. The clinical presentation of trichiasis differs according on the extent of the condition. Trichiasis can be diagnosed by assessing the patient's medical history and doing a thorough physical examination. The history encompasses the patient's medical background, record of medication usage, past eye surgical procedures, and the patient's reported symptoms. The physical examination encompasses assessments of visual acuity, biomicroscopic inspection, evaluation of eyelid margins, and the administration of the Schirmer test. The treatment for trichiasis is determined by the extent of eyelash involvement, which includes factors such as the Soft Contact Lense Base Curve. Treatment options may include eyelash removal and surgical procedures, depending on the specific form of trichiasis that the patient is suffering.
Sepsis pada Pneumonia: Literature Review Farhana, Shabrina; Wahyuni, Ari; Lisiswanti, Rika
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1075

Abstract

Sepsis is a clinical syndrome that occurs as a complication of severe infection and systemic inflammation and widespread tissue damage. Over the past three decades, the incidence of sepsis has continued to increase and has become the leading cause of death compared to other common diseases in Western countries. The incidence of sepsis reaches 750,000 every year with mortality reaching 50% in patients experiencing sepsis and septic shock. Pneumonia is the most common primary infection that occurs in sepsis patients. Pneumonia ranks third highest worldwide. Pneumonia sufferers with sepsis account for 40% of all pneumonia sufferers. Severe sepsis can be triggered by infections that occur during medical treatment or can also occur from community-acquired infections (Community Acquired Pneumonia). The aim of this literature review is to provide an overview of epidemiology, pathophysiology, clinical manifestations, and therapy that can be carried out in patients with pneumonia complicated by sepsis. The results of this literature study show that clinical manifestations in patients are influenced by the location of the infection, the type of organism, and the severity or lightness of the infection. Therapy that can be carried out in patients with pneumonia with sepsis is initial resuscitation which includes administering 0.9% NaCL for 6 hours and vasopressors to maintain the patient's hemodynamics, as well as administering empiric antibiotics followed by antibiotics according to the culture results and resistance in the patient.
Insomnia pada Mahasiswa Kedokteran: Sebuah Tinjauan Pustaka Fuad Fadillah; Lisiswanti, Rika; Rudiyanto, Waluyo; Oktafany, Oktafany
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1416

Abstract

A person who struggles to fall asleep and/or stay asleep is said to have insomnia. In Southeast Asia, 67% of 1,508 persons suffer from insomnia worldwide, and 7.3% of those who suffer from it are students. About 67% of Indonesians suffer from insomnia, with mild insomnia accounting for 55.8% and moderate insomnia for 23.3% of cases. Students who suffer from insomnia suffer, particularly those studying medicine. Medical students' usage of devices and the stress that comes with learning are linked to insomnia. By interfering with the body's sleep and wake cycle and blocking the melatonin hormone's function, using electronics at night, particularly shortly before bed, can make it difficult for the body to regulate and manage the ideal time to go to sleep and the time to be awake. Through the HPA-axis mechanism, which is triggered by corticosteroid releasing factor (CRF) and arginine vasopressin (AVP), anxiety can result in sleeplessness. This may lead the body to produce more cortisol, which would raise the wakefulness system and result in insomnia. Those who suffer from insomnia, particularly the medical students in this piece, incur unpleasant consequences. Fatigue, memory loss, and concentration issues are some of the issues that cause insomnia and impact a person's performance during the day. Disrupting concentration makes learning ineffective, which can ultimately impact medical students' performance and the quality of graduates.
Peran Resiliensi dalam Mengurangi Stres Mahasiswa Kepaniteraan Klinik: Tinjauan Pustaka Syafira Salsabila; Lisiswanti, Rika; Yuningrum, Hesti; Ramadhian, Muhammad Ricky
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1417

Abstract

The transition from the preclinical to the clinical phase of medical education, characterized by a significant difference in the learning system and increased demands, often leads to stress among medical students. A very packed schedule, tight deadlines, and the need to adapt to a dynamic clinical environment are primary stressors for medical students during their clerkship. Prolonged high levels of stress can negatively impact mental health, academic performance, and the quality of medical care, increasing the risk of medical malpractice. Resilience, defined as an individual's ability to recover from difficult situations, has proven to be a crucial protective factor in mitigating the effects of stress. Resilience is a dynamic process demonstrated when individuals take adaptive actions in the face of adversity. It is not a genetic trait but a behavior that can be developed by strengthening the factors that support it. These factors can be internal, external, or interpersonal. One way to enhance resilience is through resilience training programs that involve interactive, independent, and reflective workshops. High levels of resilience among medical students are associated with increased subjective well-being, reduced stress levels, and a more positive perception of quality of life and the educational environment. Therefore, by enhancing resilience, medical students can better cope with the pressures of clerkship, maintain mental health, and optimize academic performance in medical care.
Fluktuasi Nilai HbA2 pada Carrier β-Thalasemia: Literature Review Qoriba, Fathan; Sangging, Putu Ristyaning Ayu; Maulana, Muhammad; Lisiswanti, Rika
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1306

Abstract

Thalassemia is a form of microcytic anemia caused by impaired synthesis of the globin protein in hemoglobin, with β-thalassemia being one of the most common types. β-thalassemia arises from mutations in the β-globin gene located on chromosome 11, resulting in reduced or absent production of the β-globin chain. According to the World Health Organization (WHO, 2019), the global prevalence of β-thalassemia major is estimated at 39.96 million people (5.2% of the world’s population), with 1.5% identified as carriers. In Indonesia, the 2018 Riskesdas survey reported 7,209 cases of β-thalassemia. The decreased synthesis of the β-globin chain leads to elevated levels of HbA2 and HbF. β-thalassemia is classified into three categories: minor, intermediate, and major. This review focuses on the characteristics of HbA2 and its significance in diagnosing the β-thalassemia carrier. This article is a narrative literature review that examines various studies on HbA2 (HbA2) and its role in the β-thalassemia carrier. The literature reviewed was sourced from several databases, including PubMed, Google Scholar, and Elsevier, using the keywords "Carrier β-thalassemia" and "HbA2." The selected studies span from 2010 to 2024. Hemoglobin A (HbA) is the primary type of hemoglobin found in adults, with HbA2 and HbF serving as minor components. Individuals with β-thalassemia exhibit reduced or absent production of the β-globin chain, leading to an imbalance between α and β chains and an associated increase in HbA2 levels. Elevated HbA2 levels are commonly observed in β-thalassemia carriers, making this measurement important for predicting the risk of β-thalassemia major in their offspring. Studies suggest that HbA2 levels can be influenced by conditions such as megaloblastic anemia and iron deficiency. Additionally, factors like pregnancy and serum ferritin levels have been investigated, with mixed findings on their potential impact on HbA2 levels.  
Relationship between Student Engagement in Learning and Grade Point Average of Students Kristiani, Rini; Oktafany; Setiawan, Gigih; Lisiswanti, Rika
Medula Vol 14 No 11 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i11.1353

Abstract

Student engagement in learning is a form of student participation in the learning process. There are three dimensions in student involvement, namely behavioral, emotional, and cognitive dimensions. This study aims to find the relationship between student engagement in learning and its dimensions on GPA in students of the Medical Education Study Program, Faculty of Medicine, Lampung University (PSPD FK Unila). This research design is descriptive analytic with a cross-sectional approach conducted on students of class 2022 PSPD FK Unila with the sampling technique is total sampling. The data collection process used the University Student Engagement Inventory (USEI) questionnaire along with demographic data for GPA. The research was conducted in October-November 2024. The analysis was conducted using the spearman test. The results showed that the level of student engagement The highest was in the medium + low category totaling 168 students (80.8%), the most dominant dimension in engagement was behavioral engagement, then cognitive, and the lowest was emotional. Most students' GPA is in the very satisfactory category (64.5%), followed by praise (20.2%), and the last is satisfactory (15.3%). There was a significant relationship between student engagement in learning and GPA (p value = 0.027, r = 0.155). Further analysis found that there was a relationship between behavioral engagement on GPA (p value = 0.014, r = 0.173) and cognitive engagement on GPA (p value = 0.021, r = 0.162), while emotional engagement showed no significant relationship on GPA (p value = 0.558). There is a significant relationship between student engagement in learning and GPA in FK Unila PSPD students. The dimensions that are significantly related to GPA are the dimensions of behavioral and cognitive engagement, while the emotional dimension does not show a significant relationship to student GPA.
Budaya Keselamatan Pasien Terhadap Keselamatan Pasien Rumah Sakit : Tinjauan Pustaka Hendri, Kevin; Anggileo Pramesona, Bayu; Ganda Ratna, Maya; Lisiswanti, Rika
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1374

Abstract

Patient safety culture is an important aspect of healthcare that focuses on risk reduction and improved patient safety. Patient safety goals are efforts to prevent incidents that can harm patients and health institutions that are designed to improve patient safety by reducing the risk of injury, error, or danger during the provision of health services. Patient safety goals have six points including correct patient identification, effective communication, safety of medications that must be watched out, ensuring the correct surgical site, correct procedures and correct patients, reducing the risk of infection due to health care and reducing the risk of patients falling. Factors that affect patient safety culture include communication, lifelong learning, working hours and occupational safety culture affecting patient safety. Things that greatly contribute to the patient safety culture include openness in communication (67.54%), cooperation in hospital units (67.48%), organizational learning and sustainable development (66.90%) and non-punitive responses in case of mistakes (65.07%).  The conclusion of this study is that all units have a role in patient safety. Patient safety culture and patient safety goals are very closely related to patient safety in hospitals. However, further research is needed related to other factors that affect patient safety culture, especially regarding family involvement in patient safety.
Cystatin C sebagai Biomarker Fungsi Ginjal: Literature Review Pestalozi, George; Akbar, Fareel Wahyu; Ramadhian, Muhammad Ricky; Graharti, Risti; Lisiswanti, Rika
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1410

Abstract

Kidneys are the primary organs responsible for the excretion of metabolic waste products. Glomerular Filtration Rate (GFR) serves as a critical parameter for assessing renal function, with serum creatinine traditionally utilized as the primary biomarker. However, the accuracy of creatinine-based assessments is limited by its susceptibility to external variables, including age, sex, muscle mass, and dietary intake. These factors can lead to variability in results and reduce diagnostic precision. To overcome these limitations, cystatin C (CysC) has gained prominence as a superior alternative biomarker. Unlike creatinine, serum CysC levels are minimally influenced by external factors, offering greater stability and sensitivity in detecting acute kidney injury (AKI), chronic kidney disease (CKD), and other renal impairments such as diabetic nephropathy. Cystatin C provides notable advantages in the reclassification of CKD stages, particularly in cases where GFR measurements are borderline. CysC has demonstrated superior reliability over creatinine in predicting complications such as delayed graft function (DGF), a condition often necessitating hemodialysis. Preoperative measurement of CysC levels is instrumental in predicting long-term renal function and identifying patients at elevated risk for adverse outcomes. Elevated serum CysC concentrations in patients with renal cell carcinoma (RCC) have been correlated with poorer prognoses and an increased likelihood of postoperative renal injury. Despite its clinical advantages, the routine adoption of CysC is constrained by certain limitations. Chief among these is the significantly higher cost of CysC assays compared to traditional creatinine tests, which restricts its widespread application to confirmatory diagnostics or complex clinical scenarios.
The Role of Between Scenario Quality and Prior Knowledge on the Effectiveness of Tutorial Discussions in Problem-Based Learning (PBL): Literature Review Mu'izabby, Iffah Salma; Oktafany, Oktafany; Ratna, Maya Ganda; Lisiswanti, Rika
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1460

Abstract

Problem-Based Learning (PBL) is a learning method that puts students at the centre of the learning process, encouraging them to learn independently through problem solving. One of the main approaches in PBL is tutorial discussion, which plays an important role in promoting deep learning. The effectiveness of tutorial discussions is influenced by three main aspects: the quality of the problem scenario, students' prior knowledge, and tutor performance. The scenario should be authentic, relevant to the students' level of understanding, and able to stimulate independent learning. Students' prior knowledge also affects their contribution to the discussion, as adequate understanding allows for more active engagement. In addition, the tutor's role in facilitating the discussion also influences the success of the PBL method. The quality of the scenario and prior knowledge play an important role in the effectiveness of Problem-Based Learning (PBL) discussions, although their relationship is not always statistically significant. The quality of a well-designed scenario can stimulate meaningful discussions, motivate students, and support the achievement of learning objectives. Prior knowledge, while not necessarily determining the success of the discussion, influences how students integrate new information. Groups with lower prior knowledge can show higher discussion effectiveness through active exploration. Overall, the effectiveness of PBL is influenced by the interaction between the quality of learning design and student characteristics, suggesting the need for a holistic approach in designing PBL scenarios.
Faktor-Faktor yang Memengaruhi Empati pada Mahasiswa Kedokteran Alifah, Rahmah; Lisiswanti, Rika; Ratna, Maya Ganda; Oktafany
Medula Vol 14 No 11 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i11.1468

Abstract

Empathy in medical students is an important aspect that affects how medical students interact with patients and understand their feeling. In the medical world, empathy can enhance the doctor-patient relationship, improve patient satisfaction, and can even affect clinical outcomes. Patients who feel empathy from their doctors are more likely to fully explain their symptoms and actively engage in the doctor-patient relationship. Research shows that empathetic doctors tend to have more satisfied and compliant patients. A number of studies have identified that the level of empathy in medical students varies and is influenced by several factors. The purpose of this literature review is to identify the factors that affect empathy in medical students. The journal were obtained from Google Scholar and Pubmed database with keyword (Empathy) and (Medical Student) for publication in 2015-2024. Journal inclusion criteria used were medical student population, journals that discussed the relationship between several factors with empathy levels, and published between 2015-2024. Exclusion criteria are journals that cannot be accessed completely. The method of analysis carried out in this literature review is a descriptive method, which describes and explains through narratives of the articles found. Based on the results of review from several journals, it was found that factors such as stress, role models, empathy training, mental health, self-control, self-motivation, social awareness, and social skills, perception of learning environment, personality, self-reflection, emotional intelligence, and gratitude.