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All Journal HAYATI Journal of Biosciences Khizanah al-Hikmah : Jurnal Ilmu Perpustakaan, Informasi, dan Kearsipan Nursing News : Jurnal Ilmiah Keperawatan MIX : Jurnal Ilmiah Manajemen AFEBI Economic and Finance Review Journal of Midwifery and Nursing FITOFARMAKA: Jurnal Ilmiah Farmasi MANAGERIA: Jurnal Manajemen Pendidikan Islam Jurnal FARMAKU (Farmasi Muhammadiyah Kuningan) Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming JIMF (JURNAL ILMIAH MANAJEMEN FORKAMMA) Proceedings of International Conference on Da'wa and Communication International Journal of Economics Development Research (IJEDR) HERBAPHARMA : Journal of Herb Farmacological Jurnal Aksioma Al-Musaqoh ABDI MOESTOPO: Jurnal Pengabdian pada Masyarakat Mejuajua International Journal of Science and Society (IJSOC) Journal of Islamic Management Abdimas Indonesian Journal Journal of Islamic Economics Lariba Innovative: Journal Of Social Science Research Warta LPM International Journal of Islamicate Social Studies Al-Urwatul Wutsqo: Jurnal Ilmu Keislaman Dan Pendidikan Jurnal Siber Transportasi dan Logistik Society
Imas Maesaroh
IAIN Syekh Nurjati Cirebon
Religion Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Anticancer Activities and Metabolite Profiling of UHPLC-HRMS Method from Chrysanthemum x morifolium (Ramat.) Hemsl Leaves Maesaroh, Imas; Barliana, Melisa Intan; Abdulah, Rizky; Muhaimin, Muhaimin
HAYATI Journal of Biosciences Vol. 33 No. 1 (2026): January 2026
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.33.1.167-180

Abstract

The Chrysanthemum morifolium Ramat, traditionally used for cancer treatment, including breast cancer, possesses anticancer properties. The aim of this study is metabolite profiling using ultra-high-performance liquid chromatography in conjunction with the high-resolution mass spectrometry (UHPLC-HRMS) technique and its correlation with the cytotoxic activity of the extract and ethyl acetate fraction of Chrysanthemum x morifolium (Ramat.) Hemsl leaves on cancer cells. The ethyl acetate fraction from the hydrolyzed ethanol extract of (Chrysanthemum x morifolium (Ramat.) Hemsl) leaves has anticancer activity against the MCF-7 breast cancer cells. Metabolite profiling was used to understand the presence of metabolites that have anticancer activity. UHPLC-HRMS was used to profile their metabolites. Compound Discoverer 3.3 software finished data processing and metabolite annotation. Anticancer activity was performed using the 2-[2-methoxy-4-nitrophenyl]-3[4-nitrophenyl]-5[2,4-disulfophenyl]-2H-tetrazolium (WST-8) assay. As many as 57 secondary metabolites were identified by UHPLC-HRMS analysis. Secondary metabolites that have the potential as anti-breast cancer are glycitein, diosmetin, kaempferol, esculetin, scopoletin, dihydroartemisinin, and Chrysin, with successive percentages of 31.39%, 19.91%, 5.61%, 2.63%, 0.82%, 0.14%, and 0.05%. Ethyl acetate fraction showed stronger cytotoxic activity than ethanol extract against MCF-7 cells with IC50 values of 66.31 ppm at 24 hours incubation and 40.35 ppm at 48 hours. Further research can be conducted on the isolation of flavonoids from the ethyl acetate fraction, as well as the analysis of cell cycle apoptosis stimulation and gene expression mechanisms.
The Influence of Ownership Structure and Specific Characteristics To Capital Structure in Public Banks in Indonesia Maesaroh, Imas; H, Angga Sucitra; R, Radis Diding
AFEBI Economic and Finance Review Vol. 1 No. 1 (2016): June
Publisher : Asosiasi Fakultas Ekonomi dan Bisnis Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47312/aefr.v1i1.635

Abstract

This study aims to determine the effect of ownership structure and the specific characteristics of the capital structure in banks Indonesia. The results showed that partial ownership structure and the specific characteristics of the bank (profitability, size, and credit risk) had no significant effect on the capital structure, while the bank characteristics (expenses management) partially significant effect on the capital structure. JEL Classification: E50, G10, G21Keyword: capital structure, ownership structure, specific characteristics of bank
Analisis Total Quality Management (TQM) dalam Manajemen Operasional di Intanaya Tour and Travel Cabang Surabaya Purnama, Siska; Maesaroh, Imas
Journal of Islamic Management Vol. 1 No. 1 (2021): January
Publisher : Program Studi Manajemen Dakwah Fakultas Dakwah dan Komunikasi UIN Sunan Ampel Surabaya, UIN Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.164 KB) | DOI: 10.15642/jim.v1i1.388

Abstract

This study is to determine and analyze the concept of Total Quality Management and its implementation in the Surabaya Branch of Intanaya Tour and Travel. Researchers used descriptive qualitative methods. The results of the study illustrate that the concept of Total Quality Management in Intanaya Tour and Travel is a customer value strategy in the form of a questionnaire strategy and business planning in congregational mapping. Secondly, an organizational system in the form of employees who focus on providing customer value, a communication system that upholds service quality and a leader control system for employees. Thirdly, quality improvement at Intanaya Tour and Travel in the form of planning by the manager. The implementation of Total Quality Management at Intanaya Tour and Travel has three phases: preparation, planning and implementation. It includes an operational manager who focuses on quality control, the application of PDCA (Plan-Do-Check-Adjust) activities in the quality control system and an evaluation system for employees and congregational services.
Pengaruh Dukungan Rekan Kerja dan Keterikatan Kerja Terhadap Intensi Turnover Pada Karyawan Tetap Indomaret di Kecamatan Jonggol Maesaroh, Imas; Ahmad Fadili, Dadan
Innovative: Journal Of Social Science Research Vol. 4 No. 4 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i4.14368

Abstract

Intensi turnover pada Karyawan tetap Indomaret di Kecamatan Jonggol dapat dipengaruhi oleh berbagai faktor diantaranya dukungan rekan kerja dan keterikatan kerja karyawan. Penelitian ini bertujuan untuk menganalisis, mengetahui, dan menjelaskan mengenai pengaruh dukungan rekan kerja dan keterikatan kerja terhadap intensi turnover. Metode penelitian yang digunakan yaitu metode kuantitatif. Teknik analisis data yang digunakan yaitu analisis jalur dengan menggunakan software microsoft excel dan SPSS dengan sumber data utama yaitu kuesioner yang disebarkan kepada karyawan tetap Indomaret Kecamatan Jonggol sebanyak 100 karyawan. Hasil penelitian menunjukkan bahwa korelasi antara dukungan rekan kerja dan keterikatan kerja memiliki hubungan yang cukup kuat yaitu sebesar 0,457. Terdapat pengaruh yang negatif dan signifikan antara dukungan rekan kerja terhadap intensi turnover, terdapat pengaruh yang negatif dan signifikan antara keterikatan kerja terhadap intensi turnover, dan terdapat pengaruh secara simultan antara dukungan rekan kerja dan keterikatan kerja terhadap intensi turnover pada karyawan tetap Indomaret di Kecamatan Jonggol sebesar 14,8% sedangkan sisanya yaitu sebesar 85,2% dipengaruhi oleh variabel lain yang tidak diteliti dalam penelitian ini.
Environmentally Responsible Behavior: The Roles of Personal Norms, Perceived Value, and Destination Social Responsibility Ginting, Ginta; Dewi, Ike Janita; Maesaroh, Imas
MIX: JURNAL ILMIAH MANAJEMEN Vol 14, No 3 (2024): MIX: Jurnal Ilmiah Manajemen
Publisher : Universitas Mercu Buana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22441/jurnal_mix.2024.v14i3.002

Abstract

Objective: The objective of the study is to analyze the factors that shape tourists' environmentally responsible behavior. The proposed research model integrates norm activation theory, stakeholder theory, and a utilitarian perspective. From the norm activation theory perspective, two variables, namely awareness of consequences and ascribed responsibility, are included in the model as antecedents of personal norms. Destination social responsibility, as a stakeholder effort to promote environmental protection, can strengthen the influence of personal norms on environmentally responsible behavior. Furthermore, the utilitarian perspective in the form of perceived value, which is the benefit that tourists obtain from traveling to a destination, is also a moderating influence of personal norms on environmentally responsible behavior. Methodology: This study involved 255 respondents who had visited Yogyakarta. Data were processed using Smart-PLS to determine the relationships between variables. Finding: The results show that awareness of consequences and ascribed responsibility are factors in forming personal norms. Personal norms have a positive influence on environmentally responsible behavior. Furthermore, the data supported the role of perceived value as a moderator. However, destination social responsibility does not moderate the influence of personal norms on environmentally responsible behavior. Conclusion: The study concludes that the norms activation theory holds that personal norms are antecedents to environmentally responsible behavior. Personal norms’s influence on environmentally responsible behavior is strengthened by perceived value.
The Relationship Between Mothers' Participation Level in Integrated Health Posts (Posyandu) and the Nutritional Status of Toddlers Rukmasari, Ema Arum; Maesaroh, Imas; Mamuroh, Lilis
International Journal of Science and Society Vol 6 No 1 (2024): International Journal of Science and Society (IJSOC)
Publisher : GoAcademica Research & Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54783/ijsoc.v6i1.1077

Abstract

Mother's participation in posyandu is one of the efforts to monitor the nutritional status of children under five. However, there are still mothers who do not use health facilities for their toddlers. The purpose of this study was to determine the relationship between the level of participation of mothers in Posyandu and the nutritional status of children under five. The research method with retrospective cohort approach. The population in this study were 422 mothers with a study sample of 215 mothers. Random sampling technique. The Instrument of Nutritional Status of Children Based on Index was used in this study. Univariate and bivariate analysis of Kendall's tau_b is the analysis of the data used. The results of this study showed that the participation of active mothers to posyandu amounted to 172 people (80%) and inactive as many as 23 people (13%). The nutritional status of toddlers in Sindangkasih Village is mostly in the category of nutritional status at risk of nutrition of more than 129 toddlers (60%), good nutrition of 38 toddlers (17.7%), poor nutrition of 38 toddlers (17.7%), malnutrition of 7 toddlers (3%), nutrition of more than 2 toddlers (0.9%), and obesity of 1 toddler (0.5%). There was no relationship between maternal participation rates and the nutritional status of toddlers and gis. 0.310 > 0.05. The conclusion of the study was that there was no relationship between maternal participation and the nutritional status of toddlers with p = 0.310 > 0.05. This can be caused by a lack of knowledge and attitudes of mothers towards the nutritional status of toddlers. Community Health Centers can conduct outreach and counseling to cadres and mothers who use health services to detect nutritional problems, including malnutrition, as early as possible.
Terapi Bermain Video Game Pada Anak Usia Sekolah Dengan Diagnosa Medis Hipospadia Post Op Uretroplasti : Studi Kasus Maesaroh, Imas; Maryam, Nenden Nur Asriyani; Rukmasari, Ema Arum
Nursing News : Jurnal Ilmiah Keperawatan Vol 8, No 2 (2024)
Publisher : Tribhuwana Tunggadewi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/nn.v8i2.2929

Abstract

Hipospadia merupakan salah satu kelainan bawaan yang sering terjadi pada anak laki-laki. Penatalaksanaan yang dilakukan adalah pembedahan dan pada fase post operasi akan dirasakan nyeri akut. Studi kasus ini untuk mengetahui apakah penatalaksanaan nyeri dengan bermain game dapat mengurangi nyeri akut yang dirasakan pada anak. Tujuan studi kasus ini untuk memberikan salah satu penatalaksanaan manajemen nyeri non farmakologi terapi bermain video game untuk mengurangi  nyeri akut post op pada anak usia sekolah. Metode menggunakan studi kasus pada nyeri akut post operasi uretroplasti anak usia sekolah. Metode pengumpulan data secara primer yang dilakukan dengan wawancara, observasi, pengkajian fisik, serta secara sekunder melalui rekam medis. Intervensi keperawatan terapi bermain video game diberikan dengan durasi 3 jam per harinya. Hasil studi kasus ini yaitu penerapan terapi bermain video game pada anak usia sekolah dapat menurunkan intensitas nyeri. Manajemen nyeri dengan penatalaksanaan terapi bermain video game dapat menurunkan intensitas nyeri post op pada anak usia sekolah
Co-Authors ABDUL MUJIB Adhitama, Tias Satria Ahmad Fadili, Dadan Albert Gamot Malau Ami Pujiwati Andriyansah . Anggraeni, Silvi Annisa, Hanun Nur Aprilia, Ilma Astuti, Luvhy Dwi Bambang Aditya Nugraha Basir, Mohammad Cucu Suhartini Devi Ayuni Diputra, Angga Anugra Eha Saleha Ema Arum Rukmasari Faizal Madya Fatkhurrohmah, Nurindah Firmansyah Firmansyah Fu'adi, Ahmad Najib Ginta Ginting, Ginta H, Angga Sucitra Hadiwidjaja, Rini Dwiyani Hadiyana Sukandar, Hadiyana Hana Handayani Hanny Hafiar Hasna, Lathifah Hastuti, Hediati Hendrayanaama, Angga Sucitra Hidayah, Zainur Ike Janita Dewi Ilmi, Muhammad Nasrulloh Irmawaty Irmawaty, Irmawaty Kartikawati, Rr. Lisa Karwati, Karwati Kholis, Nur Komar Priatna, Deden Ledy Yolanda Lestari Pujiastuti, Sri Lilis Mamuroh marsigid, didik Mawaddah, Isdiadatul Meiliani Meiliani Melisa Intan Barliana, Melisa Intan Minrohayati . Muhaimin Muhaimin Muhammad Naufal, Ilham Muhrodi, Odi Nareswara, Anastu Regita Nasoha, Mohamad Nenah Sunarsih Nenden Nur Asriyani Maryam Nopiana, Medi Nur Kholis Nursolihah, Siti Pradypta, Putu Gyzca Praningtyas, Elisabeth Ria Viana Pratiwi, Adinda Syani Prawesthi, Endang Prihananto, Prihananto Puji, Sri Lestari Purnama, Siska Putri Utami, Putri R, Radis Diding Rakhmini Juwita Ria Viana Praningtya, Elisabeth Riana, Kurnia Endah Ridwan, Ridwan Rima Yulia Senja, Rima Yulia Rini Subekti Riski Maulana, Riski Rizky Abdulah Rustina, Ina Salsabila, Dania Saputra, Sherly Annisa Siti Aisyah Siti Nurasiah, Siti Sri Lestari Pujiastuti, Sri Lestari Sukmawati Sukmawati Sylvana, Andi Tarsilah, Tarsilah Thaibd, Dina Wardaya, Ahmad Wildan Wisnu Widiya Avianti Wijayanti, Silvia Wiryani, Ani Siti