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THE IMPACT OF ADMINISTRATION OF GUMITIR FLOWER SIMPLICIA OINTMENT ON COLLAGEN TISSUE DENSITY IN THE HEALING OF WHITE RAT BURNS I Gede Yoga Sukya Sumantara; I Wayan Gorda; Ida Ayu Pasti Apsari; I Made Merdana; Ida Bagus Oka Winaya
Buletin Veteriner Udayana Bul. Vet. Udayana. October 2024 Vol. 16 No. 5
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2024.v16.i05.p01

Abstract

Burns are a form of damage or loss of skin tissue caused by direct contact with heat sources such as fire, hot water, electricity and radiation. The wound healing process is not only limited to local regeneration processes, but is also greatly influenced by endogenous factors such as age, nutrition, immunology, use of drugs. One of the medicines made from nature is gumitir flowers. Gumitir flowers contain antioxidants which can help the healing process of burn wounds. This research was conducted with the aim of determining the effectiveness of administering gumitir flower simplicia ointment on collagen density in white rats that had suffered burns. In this study, 24 male Wistar rats were used and divided into 4 groups using RAL (completely randomized design). Then the mice were burned using a modified soldering iron, the wounds were made on the mice's backs at a temperature of 800C for 10 seconds. The results of the study showed that there was a difference in collagen density in the skin of white mice between white mice given gumitir flower simplicia ointment with a concentration of 0% (pure vaseline) with concentrations of 12.5%, 25% and 37.5%. The conclusion of this research is that gumitir flower simplicia ointment can help the healing process of burn wounds seen from its collagen density.
CANINE PARVOVIRUS ENTERITIS INFECTION IN LOCAL DOGS IN SAMPLANGAN VILLAGE, GIANYAR REGENCY, BALI Fauzia Hadista Anjani; Ida Bagus Kade Suardana; I Gusti Ketut Suarjana; Ida Bagus Oka Winaya; Ida Ayu Pasti Apsari
Buletin Veteriner Udayana Bul. Vet. Udayana. October 2025 Vol. 17 No. 5
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i05.p01

Abstract

A common disease that poses a threat to dogs is Canine Parvovirus (CPV). Puppies tend to be more susceptible to CPV infection due to a period called the window of susceptibility. The purpose of this case study is to determine clinical changes that include anatomical pathology, histopathology, and laboratory examinations to establish a definitive diagnosis of the case animal. The animal used in the case study was a four-month-old female local puppy from Gianyar, Bali. The case dog was found freshly dead, and had been sick for 4 days. The dog showed symptoms of weakness, anorexia, and vomiting, bloody diarrhea. Polymerase Chain Reaction (PCR) test results were positive for Canine Parvovirus infection. Anatomical pathology changes found were congestion of the brain, hemorrhage of the trachea, swelling of the heart, hemorrhage of the liver, hemorrhage of the patu-peru, hyperemia of the renal medulla, blackening and swelling of the spleen, hemorrhage of the intestines, and bleeding of the stomach. Histopathological changes observed were tracheitis, necrotizing bronchopneumonia, myocarditis, hemorrhagic glomerulo-nephritis, speinitis, gastritis, and necrotizing enteritis. Based on clinical symptoms, anatomical and histopathological pathology observations, and Polymerase Chain Reaction (PCR) results, it can be concluded that the case dog was infected with Canine Parvovirus type enteritis. It is necessary to vaccinate dogs and pay attention to environmental cleanliness to minimize the transmission of Canine Parvovirus infection.
CASE OF STREPTOCOCCOSIS IN PIGLET AT TUA VILLAGE, MARGA, TABANAN, BALI Ni Kadek Puspa Dewi; I Gusti Ketut Suarjana; Ida Bagus Kade Suardana; Ida Bagus Oka Winaya; Ida Ayu Pasti Apsari
Buletin Veteriner Udayana Bul. Vet. Udayana. June 2025 Vol. 17 No. 3
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i03.p53

Abstract

Streptococcosis is a disease caused by streptococcal bacterial infection and can cause outbreaks in pig farms. This case study aims to discuss the pathological anatomy, histopathology, and laboratory test results to obtain a definitive diagnosis of the disease that attacks 7-day-old pigs from Tua Village, Marga, Tabanan. Data collection in the form of clinical signs, anamnesis, epidemiology, and laboratory tests to be further analyzed descriptively qualitatively. Clinical signs of pig cases are thin, weak, nervous symptoms (tremors, loss of balance, lying sideways, and cycling or rowing movements), white diarrhea, fatigue, and swelling of the leg joints. Epidemiological data show a morbidity of 8.13%, mortality of 3.25%, and a case fatality rate of 40%. Pathological anatomy examination was carried out through a necropsy procedure and found congestion of the brain, heart, and intestines, hemorrhage in the lungs, kidneys, stomach, and intestines, the spleen changed color to dark and swollen and the liver was swollen and uneven in color. Histopathological examination began with the preparation of histological preparations using Hematoxylin-Eosin (HE) staining, measurements were made by observing changes descriptively using a binocular light microscope with a magnification of 100x-1000x. The results of histopathological examination showed that the brain had meningoencephalitis hemorrhagica, lungs bronchopneumonia hemorrhagica, heart myocarditis, liver hepatitis, spleen splenitis hemorrhagica, kidney glomerulonephritis hemorrhagica et necrotican, stomach Gastritis hemorrhagica et necrotican, and intestine enteritis hemorrhagica et necrotican. Examination of histopathological preparations found inflammation dominated by neutrophil cells and macrophage cells. Bacteriological examination confirmed the presence of Streptococcus sp. bacterial infection in the brain, lungs, liver, and heart organs. Based on anamnesis, clinical signs, epidemiology, examination of anatomical and histopathological pathological changes, and bacteriological examination, it can be concluded that the pigs were infected with Streptococcosis due to Streptococcus suis bacteria. In pig farming management, optimal biosecurity and sanitation must be implemented to minimize the risk of contamination by disease agents.
Co-Authors Achoiro Wati Rasid Aida Lousie Tenden Rompis Alya Nita Shena Gayanti Anak Agung Ayu Mirah Adi Anak Agung Ayu Mirah Adi Anak Agung Bagus Bramardipa Anak Agung Keswari Krisnandika Anak Agung Oka Wijaya Anak Agung Sagung Kendran Aras, Fatmawati Astuti, Ni Made Widy Matalia Baiq Renny Kamaliani BERATA BERATA Bire, Ienoliski Rohi Brigietta Vincencia Simanihuruk Cahyani, Ni Kadek Devi Desak Wiga Puspita Dewi Dewa Odiec Purnawan Djara, Devita Vanessa Sukmawati DWI SURYANTO Dzikri Nurma'rifah Takariyanti Elyda . Fatmawati Aras Fauzia Hadista Anjani Febrianty, Ni Made Dhea Guru, Yohana Cendyka Kartika Dewi Gusti Agung Ayu Putu Adriyati, Gusti Agung Ayu Gusti Ayu Yuniati Kencana Gusti Ayu Yuniati Kencana Hapsari Mahatmi Husain, Anugrah Fitria I Dewa Made Adhiwitana I Gede Made Andy Pratama I Gede Yoga Sukya Sumantara I Gusti Agung Arta Putra I Gusti Agung Gede Putra Pemayun I Gusti Ketut Suarjana I Gusti Ketut Suarjana I Gusti Ketut Suarjana I Gusti Made Krisna Erawan I Gusti Ngurah Kade Mahardika I Gusti Ngurah Kade Mahardika I Gusti Ngurah Narendra Putra1, I Kadek Parnayasa I Ketur Berata I Ketut Berata I Ketut Eli Supartika I Ketut Eli Supartika I Ketut Eli Supartika I Ketut Suarjana I Made Damriyasa I Made Dwinata I Made Kardena I Made Merdana I Made Merdana I Made Merdana I Made Sukada i Nengah Wandia I Nyoman Mantik Astawa I NYOMAN MANTIK ASTAWA I Nyoman Suarsana I Nyoman Suartha I Putu Arya Adikara I Putu Cahyadi Putra I Putu Cahyadi Putra, I Putu Cahyadi I Wayan Gorda I Wayan Gorda I Wayan Sudarmayasa I Wayan Sudira I Wayan Wirata I.K. Berata IB. KADE SUARDANA Ida Ayu Adhistania Pidada Ida Ayu Pasti Apsari Ida Ayu Pasti Apsari Ida Ayu Pasti Apsari Ida Ayu Pasti Apsari Ida Ayu Pasti Apsari Ida Ayu Sri Chandra Dewi Ida Bagus Kade Suardana Ida Bagus Kade Suardana Ida Bagus Kade Suardana Ida Bagus Komang Ardana Ida Bagus Made Oka Ida Bagus Ngurah Swacita Ida Bagus Windia Adnyana Iwan Harjono Utama Iwan Haryono Utama Kadek Karang Agustina Komang Andika Purnama Komang, Nadia Eprillia Sary Darma Ni Kurnia, Ida Ayu Gintan Aristi Luh Made Sudimartini LUH PUTU AGUSTINI Luh Putu Ratna Suhita Lutviana, An'nisafitri M. Farhan Al Ma'arif Marissa Divia Dayanti Marissa Divia Dayanti Marson, Fransiska Gratia Sonita MAS DJOKO RUDYANTO Mia Monica Ni Kadek Eka Widiadnyani Ni Kadek Nining Laksmi Dewi Ni Kadek Puspa Dewi Ni Komang Wijayani Ni Luh Aricahyani Ni Luh Eka Setiasih Ni Luh Putu Ratna Suhita Ni Nyoman Werdi Susari Ni Putu Trisna Asih NINING HARTANINGSIH Nur Baiti Palagan Senopati Sewoyo Palagan Senopati Sewoyo Pinem, Nuh Lasjuardi Purnama, Komang Andika Purnasari, Maria Elisabeth Putra, I Putu Werdikta Jayantika Putu Agus Trisna Kusuma Antara Putu Henrywaesa Sudipa Putu Intan Kusuma Wardani Rahmat Grahadi RAHMI MUSTABA Ryan Helmi Habibi Samsuri Samsuri Sartika, Nola Alfien Sartika, Nola Alfieni Sewoyo, Palagan Senopati Shafira Laili Aulia Shafira Laili Aulia Sri Kayati Widyastuti Sugiyarto - Tampubolon, Yandri Putra Lumatas Theresia Ene Tjok Gde Oka Pemayun Tjokorda Sari Nindhia Tono PG, I Ketut TRI KOMALA SARI Tyas Pandieka Yoga Velia Chyntia Victoria Wijaya, Anak Agung Gede Oka Wira, Amar Yasa, Gede Sastra Darma Yeni Ratna Sari Yeyen Agustianingsi Yolla Noviolita Yoshihiro Hayashi YUNNY DAMAYANTI Yustisia, Anggia