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All Journal Medula Juke Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati Journal Syifa Sciences and Clinical Research (JSSCR) JK Unila (Jurnal Kedokteran Universitas Lampung) Indonesian Community Empowerment Journal Jurnal Pengabdian Masyarakat JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Muhammad Ricky Ramadhian
Fakultas Kedokteran, Universitas Lampung
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Juke

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Bakteriological Quality Of Refill Drinking Water At Refill Drinking Water Depots In Bandar Lampung Ety Apriliana; M Ricky Ramadhian; Meta Gapila
JUKE Unila Vol 4, No 07 (2014)
Publisher : Fakultas Kedokteran Universitas Lampung

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Abstract

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INHERITED VARIATIONS IN DRUGS EFFECT INDEPENDENT IN PHARMACOKINETIC: POLYMORPHISM IN PHASE II BIOTRANSFORMATION ENZYMES Muhammad Ricky Ramadhian
JUKE Unila Vol 4, No 8 (2014)
Publisher : Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (235.959 KB)

Abstract

Phase II enzymes play an important role in the biotransformation of endogenous compounds and xenobiotics to more easily excretable forms as well as in the metabolic inactivation of pharmacologically active substances. The purpose of phase II biotransformation is to perform conjugating reactions. These include glucuronidation, sulfation, methylation, acetylation, glutathione, and amino acid conjugation. In general, the respective conjugates are more hydrophilic than the parent compounds. Polymorphism in Phase II drug metabolism enzymes may have role in diseases, cancer, and others. This review discuss brief about polymorphism in Phase II drug metabolism enzyme. [JuKe Unila 2014; 4(8):254-268]
Co-Authors Ade Marantika Adisti, Fransiska Afriyani, Afriyani Akbar, Fareel Wahyu Anggraini, Dian Isti Aprina Adha Widiastini Asep Sukohar Atika Threenesia Balqis, Aurelia Corrinna Benny Bradley Pradana Pangaribuan Betta Kurniawan, Betta Daulay, Suryani Agustina Delvi Rusitaini Putri Diana Mayasari Efrida Warganegara Ekki Pirmansyah Ermin Rachmawati Ety Apriliana Ety Apriliana Falamy, Ryan Farhry Alvini Rahmania Fitria, Aghniya Rizqy George Pestalozi Gultom, Dea Debora Romauli Hanna Mutiara, Hanna Hendra Tarigan Sibero Intanri Kurniati Iswandi Darwis Jhons Fatriyadi Suwandi Khairil Pahmi Khairil Pahmi Khairun Nisa Kurniawaty, Evi Lusina, Septia Eva M Sidratullah Marcellia, Selvi Meta Gapila Muhammad Maulana Muhammad Taupik Nadhifa, Farin Nasution, Salwa Salsabila Nora Ramkita Novita Carolia Nurul Sahana Rahmadhini Nurul Utami Oktadoni Saputra, Oktadoni Putri, Abrila Tamara Ratna, Maya Ganda Reni Zuraida Rifda Khairunnisa Rika Lisiswanti Risti Graharti Septiani, Linda Shinta Nareswari, Shinta Suryadi Islami Sutarto Sutarto Syafira Salsabila Syazili Mustofa Tri Umiana Sholeha Tri Umiana Soleha Tri Umiana Soleha Yuniarti, Wulan Yuningrum, Hesti